Enzyme kinetics of zearalenone biotransformation: pH and cofactor effects

Archives of Toxicology

Volumn 79, Issue 10, 2005, Pages 547-553

  Malekinejad, H ^a   Maas Bakker, R F ^a   Fink Gremmels, J ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Zearalenol; Zearalenol; Cofactors; Hepatic biotransformation; Hydroxysteroid dehydrogenase; Zearalenone

Indexed keywords

3(OR 17)BETA HYDROXYSTEROID DEHYDROGENASE; 3ALPHA HYDROXYSTEROID DEHYDROGENASE; ALPHA ZEARALENOL; ANDROSTANEDIONE; BETA ZEARALENOL; PREGNENOLONE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; ZEARALENONE;

ANIMAL TISSUE; ARTICLE; BIOTRANSFORMATION; CELL FRACTIONATION; CONTROLLED STUDY; ENZYME KINETICS; ENZYME SUBSTRATE; IN VITRO STUDY; LIVER METABOLISM; LIVER MICROSOME; LIVER MITOCHONDRION; MALE; METABOLITE; NONHUMAN; PH; PRIORITY JOURNAL; SWINE; TOXICOKINETICS; VELOCITY;

3-ALPHA-HYDROXYSTEROID DEHYDROGENASE (B-SPECIFIC); ANDROSTANES; ANIMALS; BINDING, COMPETITIVE; BIOTRANSFORMATION; COENZYMES; ETIOCHOLANOLONE; HYDROGEN-ION CONCENTRATION; KINETICS; MALE; MICROSOMES, LIVER; MITOCHONDRIA, LIVER; MYCOTOXINS; NAD; NADP; PREGNENOLONE; SWINE; ZEARALENONE; ZERANOL;

SUIDAE; SUS SCROFA;

EID: 26944450472     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-005-0664-6     Document Type: Article

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