-
1
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. 1994 Positional cloning of the mouse obese gene and its human homologue. Nature. 372:425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
2
-
-
0029066265
-
Effects of the obese gene product on body weight regulation in ob/ob mice
-
Pelleymounter MA, Cullen MJ, Baker MB, et al. 1995 Effects of the obese gene product on body weight regulation in ob/ob mice. Science. 269:540-543.
-
(1995)
Science
, vol.269
, pp. 540-543
-
-
Pelleymounter, M.A.1
Cullen, M.J.2
Baker, M.B.3
-
3
-
-
0029048408
-
Recombinant mouse OB protein: Evidence for a peripheral signal linking adiposity and central neural networks
-
Campfield LA, Smith FJ, Guisez Y, Devos R, Burn P. 1995 Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science. 269:546-549.
-
(1995)
Science
, vol.269
, pp. 546-549
-
-
Campfield, L.A.1
Smith, F.J.2
Guisez, Y.3
Devos, R.4
Burn, P.5
-
4
-
-
2442654859
-
Identification and expression cloning of a leptin receptor, OB-R
-
Tartalgia LA, Dembski M, Weng X, et al. 1995 Identification and expression cloning of a leptin receptor, OB-R. Cell. 83:1263-1271.
-
(1995)
Cell
, vol.83
, pp. 1263-1271
-
-
Tartalgia, L.A.1
Dembski, M.2
Weng, X.3
-
5
-
-
0031010408
-
Anatomic localization of alternatively spliced leprin receptors (Ob-R) in mouse brain and other tissues
-
Fei H, Okano HJ, Li C, et al. 1997 Anatomic localization of alternatively spliced leprin receptors (Ob-R) in mouse brain and other tissues. Proc Natl Acad Sci USA. 94:7001-7005.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 7001-7005
-
-
Fei, H.1
Okano, H.J.2
Li, C.3
-
6
-
-
0030434655
-
Leptin and OB-R: Body weight regulation by a cytokine receptor
-
White DW, Tartalgia LA. 1996 Leptin and OB-R: body weight regulation by a cytokine receptor. Cytokine Growth Factor Rev. 7:303-309.
-
(1996)
Cytokine Growth Factor Rev
, vol.7
, pp. 303-309
-
-
White, D.W.1
Tartalgia, L.A.2
-
7
-
-
0030015417
-
Defective STAT signaling by the leptin receptor in diabetic mice
-
Ghilardi N, Ziegler S, Wiestner A, Stoffel R, Heim MH, Skoda RC. 1996 Defective STAT signaling by the leptin receptor in diabetic mice. Proc Natl Acad Sci USA. 93:6231-6235.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6231-6235
-
-
Ghilardi, N.1
Ziegler, S.2
Wiestner, A.3
Stoffel, R.4
Heim, M.H.5
Skoda, R.C.6
-
8
-
-
0029739826
-
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice
-
Vaisse C, Halaas JL, Horvath CM, Darnell Jr JE, Stoffel M, Friedman JM. 1996 Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice. Nat Genet. 14:95-97.
-
(1996)
Nat Genet
, vol.14
, pp. 95-97
-
-
Vaisse, C.1
Halaas, J.L.2
Horvath, C.M.3
Darnell Jr., J.E.4
Stoffel, M.5
Friedman, J.M.6
-
9
-
-
0030250892
-
A role for leptin and its cognate receptor in hematopoiesis
-
Bennett BD, Solar GP, Yuan JQ, Mathias J, Thomas GR, Matthews W. 1996 A role for leptin and its cognate receptor in hematopoiesis. Curr Biol. 6:1170-1180.
-
(1996)
Curr Biol
, vol.6
, pp. 1170-1180
-
-
Bennett, B.D.1
Solar, G.P.2
Yuan, J.Q.3
Mathias, J.4
Thomas, G.R.5
Matthews, W.6
-
10
-
-
0023720145
-
Human fetal adenohypophysis. Electron microscopy and ultrastructural immunocytochemical analysis
-
Asa SL, Kovacs K, Horvath E, et al. 1988 Human fetal adenohypophysis. Electron microscopy and ultrastructural immunocytochemical analysis. Neuroendocrinology. 48:423-431.
-
(1988)
Neuroendocrinology
, vol.48
, pp. 423-431
-
-
Asa, S.L.1
Kovacs, K.2
Horvath, E.3
-
11
-
-
0025869055
-
Human fetal adenohypophysis: Morphological and functional analysis in vitro
-
Asa SL, Kovacs K, Singer W. 1991 Human fetal adenohypophysis: morphological and functional analysis in vitro. Neuroendocrinology. 53:562-572.
-
(1991)
Neuroendocrinology
, vol.53
, pp. 562-572
-
-
Asa, S.L.1
Kovacs, K.2
Singer, W.3
-
12
-
-
0027278474
-
Effects of growth hormone (GH)-releasing factor and somatostatin on GH secretion from early to midgestation human fetal piruitaries
-
Goodyer CG, Branchaud CL, Lefebvre Y. 1993 Effects of growth hormone (GH)-releasing factor and somatostatin on GH secretion from early to midgestation human fetal piruitaries. J Clin Endocrinol Metab. 76:1259-1264.
-
(1993)
J Clin Endocrinol Metab
, vol.76
, pp. 1259-1264
-
-
Goodyer, C.G.1
Branchaud, C.L.2
Lefebvre, Y.3
-
13
-
-
0021746013
-
Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction
-
Williams T, Berelowitz M, Joffe SN, et al. 1984 Impaired growth hormone responses to growth hormone-releasing factor in obesity. A pituitary defect reversed with weight reduction. N Engl J Med. 311:1403-1407.
-
(1984)
N Engl J Med
, vol.311
, pp. 1403-1407
-
-
Williams, T.1
Berelowitz, M.2
Joffe, S.N.3
-
14
-
-
0027745253
-
National Advisory Panel on Ethics in reproduction. Policy forum: The future of the fetal tissue bank
-
Cohen CB, Jonsen Ar. 1993 National Advisory Panel on Ethics in reproduction. Policy forum: the future of the fetal tissue bank. Science. 262:1663-1665.
-
(1993)
Science
, vol.262
, pp. 1663-1665
-
-
Cohen, C.B.1
Jonsen, Ar.2
-
15
-
-
0030754627
-
Cytokine-dependent gp130 receptor subunit regulates human fetal pituitary adrenocorticotropin hormone and growth hormone
-
Shimon I, Yan X, Ray DW, Melmed S. 1997 Cytokine-dependent gp130 receptor subunit regulates human fetal pituitary adrenocorticotropin hormone and growth hormone. J Clin Invest. 100:357-363.
-
(1997)
J Clin Invest
, vol.100
, pp. 357-363
-
-
Shimon, I.1
Yan, X.2
Ray, D.W.3
Melmed, S.4
-
16
-
-
0028117163
-
Cytokine signal transduction
-
Kishimoto T, Taga T, Akira S. 1994 Cytokine signal transduction. Cell. 76:253-262.
-
(1994)
Cell
, vol.76
, pp. 253-262
-
-
Kishimoto, T.1
Taga, T.2
Akira, S.3
-
17
-
-
0029776030
-
The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors
-
Baumann H, Morella KK, White DW, et al. 1996 The full-length leptin receptor has signaling capabilities of interleukin 6-type cytokine receptors. Proc Natl Acad Sci USA. 93:8374-8378.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 8374-8378
-
-
Baumann, H.1
Morella, K.K.2
White, D.W.3
-
19
-
-
0031019079
-
Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat
-
Zamorano PL, Mahesh VB, De Sevilla LM, Chorich LP, Bhat GK, Brann DW. 1997 Expression and localization of the leptin receptor in endocrine and neuroendocrine tissues of the rat. Neuroendocrinology. 65:223-228.
-
(1997)
Neuroendocrinology
, vol.65
, pp. 223-228
-
-
Zamorano, P.L.1
Mahesh, V.B.2
De Sevilla, L.M.3
Chorich, L.P.4
Bhat, G.K.5
Brann, D.W.6
-
20
-
-
0030010388
-
Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin
-
Chebab FF, Lim ME, Lu R. 1996 Correction of the sterility defect in homozygous obese female mice by treatment with the human recombinant leptin. Nat Genet. 12:318-320.
-
(1996)
Nat Genet
, vol.12
, pp. 318-320
-
-
Chebab, F.F.1
Lim, M.E.2
Lu, R.3
-
21
-
-
0031019763
-
Role of leptin in hypothalamic-pituitary function
-
Yu WH, Kimura M, Walczewska A, Karanth S, McCann SM. 1997 Role of leptin in hypothalamic-pituitary function. Proc Natl Acad Sci USA. 94:1023-1028.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 1023-1028
-
-
Yu, W.H.1
Kimura, M.2
Walczewska, A.3
Karanth, S.4
McCann, S.M.5
-
22
-
-
0031014413
-
Early onset of reproductive function in normal female mice treated with leptin
-
Chehab FF, Mounzih K, Lu R, Lim ME. 1997 Early onset of reproductive function in normal female mice treated with leptin. Science. 275:88-90.
-
(1997)
Science
, vol.275
, pp. 88-90
-
-
Chehab, F.F.1
Mounzih, K.2
Lu, R.3
Lim, M.E.4
-
23
-
-
0030868077
-
Leptin accelerates the onset of puberty in normal female mice
-
Ahima RX, Dushay J, Flier SN, Prabakaran D, Flier JS. 1997 Leptin accelerates the onset of puberty in normal female mice. J Clin Invest. 99:391-395.
-
(1997)
J Clin Invest
, vol.99
, pp. 391-395
-
-
Ahima, R.X.1
Dushay, J.2
Flier, S.N.3
Prabakaran, D.4
Flier, J.S.5
-
24
-
-
0029953957
-
Leptin is a metabolic signal to the reproductive system
-
Barash IA, Cheung CC, Weigle DS, et al. 1996 Leptin is a metabolic signal to the reproductive system. Endocrinology. 137:3144-3147.
-
(1996)
Endocrinology
, vol.137
, pp. 3144-3147
-
-
Barash, I.A.1
Cheung, C.C.2
Weigle, D.S.3
-
25
-
-
16944364768
-
Human leptin levels are pulsatile and inversely related to pituitary-adrenal function
-
Licinio J, Mantzoros C, Negaro AB, et al. 1997 Human leptin levels are pulsatile and inversely related to pituitary-adrenal function. Nat Med. 3:575-579.
-
(1997)
Nat Med
, vol.3
, pp. 575-579
-
-
Licinio, J.1
Mantzoros, C.2
Negaro, A.B.3
-
26
-
-
0030937007
-
Regulation of in vivo growth hormone secretion by leptin
-
Carro E, Senaris R, Considine RV, Casanueva FF, Dieguez C. 1997 Regulation of in vivo growth hormone secretion by leptin. Endocrinology 138:2203-2206.
-
(1997)
Endocrinology
, vol.138
, pp. 2203-2206
-
-
Carro, E.1
Senaris, R.2
Considine, R.V.3
Casanueva, F.F.4
Dieguez, C.5
-
27
-
-
0030683692
-
Leptin inhibits in vitro hypothalamic somatostatin secretion and somatostatin mRNA levels
-
Quintela M, Senaris R, Heiman ML, Casanueva FF, Dieguez C. 1997 Leptin inhibits in vitro hypothalamic somatostatin secretion and somatostatin mRNA levels. Endocrinology. 138:5641-5644.
-
(1997)
Endocrinology
, vol.138
, pp. 5641-5644
-
-
Quintela, M.1
Senaris, R.2
Heiman, M.L.3
Casanueva, F.F.4
Dieguez, C.5
-
28
-
-
0029131574
-
Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity
-
Frederich RC, Lollmann B, Hamann A, et al. 1996 Expression of ob mRNA and its encoded protein in rodents. Impact of nutrition and obesity. J Clin Invest. 96:1658-1663.
-
(1996)
J Clin Invest
, vol.96
, pp. 1658-1663
-
-
Frederich, R.C.1
Lollmann, B.2
Hamann, A.3
-
29
-
-
0031023373
-
Effects of food deprivation on the GH axis: Immunocytochemical and molecular analysis
-
Brogan RS, Fife SK, Conley LK, Giustina A, Wehrenberg WB. 1997 Effects of food deprivation on the GH axis: immunocytochemical and molecular analysis. Neuroendocrinology. 65:129-135.
-
(1997)
Neuroendocrinology
, vol.65
, pp. 129-135
-
-
Brogan, R.S.1
Fife, S.K.2
Conley, L.K.3
Giustina, A.4
Wehrenberg, W.B.5
-
30
-
-
0028836575
-
Adults with growth hormone deficiency have abnormal body composition hut normal energy metabolism
-
Hoffman DM, O'Sullivan AJ, Freund J, Ho KK. 1995 Adults with growth hormone deficiency have abnormal body composition hut normal energy metabolism. J Clin Endocrinol Metab. 80:72-77.
-
(1995)
J Clin Endocrinol Metab
, vol.80
, pp. 72-77
-
-
Hoffman, D.M.1
O'Sullivan, A.J.2
Freund, J.3
Ho, K.K.4
-
31
-
-
0024854194
-
The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency
-
Salomon F, Cuneo RC, Hesp RC, Sonksen PH. 1989 The effects of treatment with recombinant human growth hormone on body composition and metabolism in adults with growth hormone deficiency. N Engl J Med. 321:1797-1803.
-
(1989)
N Engl J Med
, vol.321
, pp. 1797-1803
-
-
Salomon, F.1
Cuneo, R.C.2
Hesp, R.C.3
Sonksen, P.H.4
-
32
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
Halaas JL, Gajiwala KS, Maffei M, et al. 1995 Weight-reducing effects of the plasma protein encoded by the obese gene. Science. 269:543-546.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
-
34
-
-
0030929962
-
Leptin concentration in cord blood correlates with intrauterine growth
-
Koistinen HA, Koivisto VA, Andersson S, et al. 1997 Leptin concentration in cord blood correlates with intrauterine growth. J Clin Endocrinol Metab. 82:3328-3330.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 3328-3330
-
-
Koistinen, H.A.1
Koivisto, V.A.2
Andersson, S.3
-
35
-
-
0030911730
-
Functional GH receptors and GH are expressed by preimplantation mouse embryos: A role for GH in early embryogenesis?
-
Pantaleon M, Whiteside EJ, Harvey MB, Barnard RT, Waters MJ. 1997 Functional GH receptors and GH are expressed by preimplantation mouse embryos: a role for GH in early embryogenesis? Proc Natl Acad Sci USA. 94:5125-5130.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 5125-5130
-
-
Pantaleon, M.1
Whiteside, E.J.2
Harvey, M.B.3
Barnard, R.T.4
Waters, M.J.5
-
36
-
-
0029812890
-
Ontogeny of GH receptors in human tissues: An immunohistochemical study
-
Simard M, Manthos H, Giaid A, Lefebvre, Goodyer CG. 1996 Ontogeny of GH receptors in human tissues: an immunohistochemical study. J Clin Endocrinol Metab. 81:3097-3102.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 3097-3102
-
-
Simard, M.1
Manthos, H.2
Giaid, A.3
Lefebvre4
Goodyer, C.G.5
-
37
-
-
0031792737
-
Human fetal pituitary expresses functional growth hormone (GH) releasing peptide receptors
-
Shimon I, Yan X, Melmed S. 1998 Human fetal pituitary expresses functional growth hormone (GH) releasing peptide receptors. J Clin Endocrinol Metab. 83:174-178.
-
(1998)
J Clin Endocrinol Metab
, vol.83
, pp. 174-178
-
-
Shimon, I.1
Yan, X.2
Melmed, S.3
|