7,12-dimethylbenz[a]anthracene-induced bone marrow toxicity is p53-dependent

Toxicological Sciences

Volumn 74, Issue 1, 2003, Pages 85-92

  Page, Todd J ^a   O'Brien, Scott ^a   Holston, Karrie ^a   MacWilliams, Peter S ^a   Jefcoate, Colin R ^a   Czuprynski, Charles J ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Apoptosis; B cell; Bone marrow; DMBA; p53; PAH

Indexed keywords

7,12 DIMETHYLBENZ[A]ANTHRACENE; CARCINOGEN; CASPASE 8; CASPASE 9; CYTOCHROME P450 1B1; IMMUNOTOXIN; POLYCYCLIC AROMATIC HYDROCARBON; PROTEIN P53;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW CELL; BONE MARROW TOXICITY; CARCINOGENICITY; CELL COUNT; COCULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; EVIDENCE BASED MEDICINE; FEMALE; IMMUNOTOXICITY; IN VITRO STUDY; KNOCKOUT MOUSE; MALE; MOUSE; NONHUMAN; PRE B LYMPHOCYTE; SIGNAL TRANSDUCTION; STEM CELL; STROMA CELL;

9,10-DIMETHYL-1,2-BENZANTHRACENE; ANIMALS; APOPTOSIS; B-LYMPHOCYTES; BONE MARROW CELLS; CARCINOGENS; CELL COUNT; CELLS, CULTURED; COLORING AGENTS; FEMALE; GENE EXPRESSION REGULATION; GENES, P53; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROPIDIUM; STEM CELLS; STROMAL CELLS; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA;

EID: 0037817790     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/kfg115     Document Type: Article

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