Adaptive evolution of the human fatty acid synthase gene: Support for the cancer selection and fat utilization hypotheses?

Gene

Volumn 360, Issue 2, 2005, Pages 151-159

  O'Connell, Mary J ^a   McInerney, James O ^b  

^a DUBLIN CITY UNIVERSITY   (Ireland)

^b NATIONAL UNIVERSITY OF IRELAND   (Ireland)

Author keywords

Brain size; Darwinian selection; Metabolism; Protein evolution; Selection

Indexed keywords

FATTY ACID SYNTHASE; MITOGEN ACTIVATED PROTEIN KINASE 1; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2;

ADAPTATION; ARTICLE; CANCER; EVOLUTION; FATTY ACID SYNTHESIS; GENETIC ANALYSIS; GENETIC SELECTION; HUMAN; LIPID METABOLISM; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

EVOLUTION; FATTY ACID SYNTHETASE COMPLEX; FATTY ACIDS; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MODELS, BIOLOGICAL; NEOPLASMS; PROTO-ONCOGENE PROTEINS;

MAMMALIA; VERTEBRATA;

EID: 26844564666     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.gene.2005.06.020     Document Type: Article

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