Glucose transporter-2 (GLUT2) promoter mediated transgenic insulin production reduces hyperglycemia in diabetic mice

FEBS Letters

Volumn 579, Issue 25, 2005, Pages 5759-5764

  Burkhardt, Brant R ^a,b   Parker, Mathew J ^a   Zhang, Y Clare ^a   Song, Sihong ^a   Wasserfall, Clive H ^a   Atkinson, Mark A ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Gene therapy; Glucose transporter 2; Insulin; Liver; Type 1 diabetes

Indexed keywords

BOVINE INSULIN; C PEPTIDE; FURIN; GLUCOSE TRANSPORTER 2; LINBIT; PARVOVIRUS VECTOR; PREPROINSULIN; PROTEIN SUBUNIT; RECOMBINANT HUMAN INSULIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL STRAIN HEPG2; CONTROLLED STUDY; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; HYPERGLYCEMIA; INSULIN BLOOD LEVEL; INSULIN DEPENDENT DIABETES MELLITUS; INSULIN RELEASE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PORTAL VEIN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; STREPTOZOCIN DIABETES; SUSTAINED RELEASE PREPARATION; TRANSGENIC MOUSE; VIRAL GENE DELIVERY SYSTEM; VIRUS CAPSID; VIRUS RECOMBINANT;

ANIMALS; BLOOD GLUCOSE; DEPENDOVIRUS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; GENE THERAPY; GLUCOSE; GLUCOSE TRANSPORTER TYPE 2; HUMANS; INSULIN; LIVER; MICE; PROMOTER REGIONS (GENETICS); TRANSGENES;

ADENO-ASSOCIATED VIRUS; MIRIDAE; MURINAE;

EID: 26844501322     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2005.09.060     Document Type: Article

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