Enzyme redesign: Two mutations cooperate to convert cycloartenol synthase into an accurate lanosterol synthase

Journal of the American Chemical Society

Volumn 127, Issue 41, 2005, Pages 14132-14133

  Lodeiro, Silvia ^a   Schulz Gasch, Tanja ^b   Matsuda, Seiichi P T ^a  

^a RICE UNIVERSITY   (United States)

^b F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOARTENOL SYNTHASE; LANOSTEROL SYNTHASE;

ARTICLE; ENZYME ENGINEERING; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; MUTAGENESIS; MUTATION;

ANIMALS; ARABIDOPSIS; CATALYSIS; ENZYME ACTIVATION; INTRAMOLECULAR TRANSFERASES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MUTAGENESIS; PROTEIN CONFORMATION; PROTEIN ENGINEERING; SQUALENE;

EID: 26844446540     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja053791j     Document Type: Article

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