1α,25-dihydroxyvitamin D3 stimulates steroid sulphatase activity in HL60 and NB4 acute myeloid leukaemia cell lines by different receptor-mediated mechanisms

Journal of Cellular Biochemistry

Volumn 94, Issue 6, 2005, Pages 1175-1189

  Hughes, Philip J ^a   Steinmeyer, Andreas ^b   Chandraratna, Roshantha A S ^c   Brown, Geoffrey ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b BAYER PHARMA AG   (Germany)

^c ALLERGAN INC   (United States)

Author keywords

1 ,25 dihydroxyvitamin D3; Membrane associated vitamin D receptor; Myeloid cells; Nuclear vitamin D receptor; Steroid sulphatase

Indexed keywords

1,3,24 TRIHYDROXY 26,27 CYCLO 9,10 SECOCHOLESTA 5,7,10(19),22 TETRAENE 25 CARBOXYLIC ACID BUTYL ESTER; 1ALPHA,25 DIHYDROXYLUMISTEROL 3; AGN 194310; AGN 195393; ANDROGEN; CALCITRIOL; COLECALCIFEROL DERIVATIVE; ESTROGEN; RECEPTOR BLOCKING AGENT; RETINOID X RECEPTOR; STERYL SULFATASE; UNCLASSIFIED DRUG; VITAMIN D DERIVATIVE; VITAMIN D RECEPTOR; XYLAZINE; CALCITRIOL RECEPTOR; CHOLESTEROL; MEMBRANE LIPID;

ACUTE GRANULOCYTIC LEUKEMIA; ARTICLE; BIOSYNTHESIS; BONE MARROW CELL; CELL MEMBRANE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME REGULATION; HUMAN; HUMAN CELL; LEUKEMIA CELL; PRIORITY JOURNAL; DRUG ANTAGONISM; ENZYME ACTIVATION; METABOLISM; PHYSIOLOGY; TUMOR CELL LINE; UPREGULATION;

CALCITRIOL; CELL LINE, TUMOR; CHOLESTEROL; ENZYME ACTIVATION; HUMANS; MEMBRANE LIPIDS; RECEPTORS, CALCITRIOL; STERYL-SULFATASE; UP-REGULATION;

EID: 26444502685     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20377     Document Type: Article

References (69)

1. 3. J Cell Biochem 78:34-46.
2. Belandia B, Parker MG. 2003. Nuclear receptors: A rendezvous for chromatin remodelling factors. Cell 114:277-280.
3. Berger C, Horrocks B, Datta H. 1999. Direct non-genomic effect of steroid hormones on superoxide anion generation in bone resorbing osteoclasts. Mol Cell Endocrinol 148:53-59.
4. 3 prime NB4 cells for monocytic differentiation via non-genomic signalling pathways involving calcium and calpain. Endocrinol 140:4779-4788.
5. 3 stimulates expression and translocation of protein kinase Cα and Cδ via a non-genomic mechanism and rapidly induces phosphorylation of a 33-kDa protein in acute promyelocytic NB4 cells. J Biol Chem 271:16090-16096.
6. 3 stimulates phosphorylation of IκBα and synergises with NF-κB during monocytic differentiation of NB4 leukaemia cells. Exp Cell Res 272:176-184.
7. Bettoun D, Burris T, Houck K, Buck D, Stayrook K, Khalifa B, Lu J, Chin W, Nagpal S. 2003. Retinoid X receptor is a non-silent major contributor to vitamin D receptor-mediated transcriptional activation. Mol Endocrinol 17:2320-2328.
8. Bettoun D, Lu J, Khalifa B, Lee Y, Chin W, Nagpal S. 2004. Ligand modulates VDR-Ser/Thr protein phosphatase interaction and p70S6 kinase phosphorylation in a cell-context-dependent manner. J Steroid Biochem Molec Biol 89-90:195-198.
9. 3 is independent of nuclear receptor binding. J Biol Chem 270:15962-15965.
10. 3 by VDR-dependent and -independent mechanisms in muscle cells. Steroids 67:477-482.
11. Broquet A, Thomas G, Masliah J, Trugnan G, Bachelet M. 2003. Expression of the molecular chaperone Hsp70 in detergent-resistant microdomains correlates with its membrane delivery and release. J Biol Chem 278:21601-21606.
12. 3 regulation of the map kinase pathway in muscle cells. J Biol Chem 278:2199-2205.
13. 3 induces the translocation of the vitamin D receptor (VDR) to the plasma membrane in skeletal muscle cells. J Cell Biochem 86:128-135.
14. 3 in MCF-7 breast cancer cells. J Cell Biochem 98:384-397.
15. Carlberg C. 2003a. Current understanding of the function of the nuclear vitamin D receptor in response to its natural and synthetic ligands. Recent Results Cane Res 164:29-42.
16. Carlberg C. 2003b. Molecular basis of the selective activity of vitamin D analogues. J Cell Biochem 88:274-281.
17. 3-induced differentiation in human osteoblasts. Immunopharmacol Immunotoxicol 21:31-41.
18. De Boland A, Boland R. 1994. Non-genomic signal transduction pathway of vitamin D. Cell Signal 6:717-724.
19. 3 in primary human keratinocytes. J Cell Biochem 93:951-967.
20. 3- transactivation of the rat cytochrome p450C24 (CYP24) promoter. Specific functions for ERK1/ERK2 and ERK5. J Biol Chem 277:29643-29653.
21. + channels. J Membr Biol 90:137-143.
22. Enjuanes A, Garcia-Giralt N, Supervia A, Nogues X, Melibovsky L, Carbonell J, Grinberg D, Balcells S, Diez-Perez A. 2003. Regulation of CYP19 gene expression in primary human osteoblasts: Effects of vitamin D and other treatments. Eur J Endocrinol 148:519-526.
23. 3 in human keratinocytes. J Invest Derm 106:1212-1217.
24. Hammond L, Van Krinks C, Durham J, Tomkins S, Burnett R, Jones E, Chandraratna R, Brown G. 2001. Antagonists of retinoic acid receptors (RARs) are potent growth inhibitors of prostate carcinoma cells. Br J Cancer 85:453-462.
25. 3-induced myeloid cell differentiation is regulated by a vitamin D receptor-phosphatidylinositol 3-kinase signalling complex. J Exp Med 190:1583-1594.
26. 3. Biochem J 365:361-371.
27. 3 in vivo and in vitro. Mol Endocrinol 18:2660-2671.
28. Huo H, Guo X, Hong S, Jiang M, Liu X, Liao K. 2003. Lipid rafts/caveolae are essential for insulin-like growth factor-1 receptor signalling during 3T3-L1 pre-adipocyte differentiation induction. J Biol Chem 278:11561-11569.
29. Jacob F, Homann D, Adamski J. 1995. Expression of aromatase and 17β-hydroxysteroid dehydrogenase type 4 in human THP1 leukaemia cells. J Steroid Biochem Molec Biol 55:555-567.
30. 3-induced monocytic differentiation of HL60 cells. Cane Res 64:370-377.
31. 3, involves nuclear vitamin D receptor (nVDR) and non-nVDR-mediated pathways. J Cell Physiol 191:198-207.
32. 3 stimulates activator protein 1 DNA-binding activity by a phosphatidylinositol 3-kinase/Ras/MEK/ extracellular signal regulated kinase 1/2 and c-jun N-terminal kinase 1-dependent increase in c-Fos, Fra1, and c-jun expression in human keratinocytes. J Invest Dermatol 120:561-570.
33. 2+ concentration in pancreatic β-cells through non-genomic signal transduction. Endocrinol 140:4706-4712.
34. 3-occupied vitamin D receptors with cellular membrane acceptance sites. Endocrinology 137:3649-3658.
35. Kinuta K, Tanaka H, Moriake T, Aya K, Kato S, Seino Y. 2000. Vitamin D is an important factor in estrogen biosynthesis in both female and male gonads. Endocrinology 141:1317-1324.
36. 3. I. Calcium transport, receptor kinetics and signal transduction in intestine of male chickens. Endocrinol 144:1726-1735.
37. Lee J, Hmama Z, Mui A, Reiner N. 2004. Stable gene silencing in human monocytic cell lines using lentiviral-delivered siRNA: Silencing of the p110α isoform of phosphoinositide 3-kinase reveals differential regulation of adherence induced by 1α,25-dihydroxycholecalciferol and bacterial lipopolysaccharide. J Biol Chem 279:9379-9388.
38. Li H, Appelbaum F, Wilman C, Zager R, Banker D. 2003. Cholesterol-modulating agents kill acute myeloid cells and sensitize them to therapeutics by blocking adaptive cholesterol responses. Blood 101:3628-3634.
39. 3-induced differentiation of HL-60 cells. Biochem J 331:21-27.
40. Marcinkowska E, Kutner A. 2002. Side chain modified vitamin D analogs require activation of both PI 3-K and Erk1,2 signal transduction pathways to induce differentiation of human promyelocytic leukaemia cells. Acta Biochim Pol 48:393-406.
41. 3 stimulation of calcium uptake by rat intestinal cells involves a dihydropyridine-sensitive cAMP-dependent pathway. Cell Signalling 3:299-304.
42. 3-26,23-lactone analogs antagonize differentiation of human leukaemia (HL-60 cells) but not of human acute promyelocytic leukaemia cells (NB4 cells). FEBS Letts 460:297-302.
43. 3. J Cell Biochem 91:852-863.
44. 3 signaling. Proc Natl Acad Sci USA 101:12876-12881.
45. Mountford J, Bunce C, Hughes S, Drayson M, Webb D, Hewison M. 1999. Estrone potentiates myeloid cell differentiation a role for 17β- hydroxysteroid dehydrogenase in modulating hemopoiesis. Exp Haematol 27:451-460.
46. Nakata T, Takashima T, Shiotsu Y, Murakata C, Ishida H, Akinaga S, Li P, Sasano H, Suzuki T, Saeki T. 2003. Role of steroid sulphatase in local formation of estrogen in post-menopausal breast cancer patients. J Ster Biochem Molec Biol 86:455-460.
47. 3. Endocrinology 115:1476-1483.
48. 3-MARRS) and phosphate uptake in intestinal cells. Proc Natl Acad Sci 101:7392-7397.
49. 3 require the VDR and influence 24-hydroxylase activity: Studies in human skin fibroblasts bearing vitamin D receptor mutations. J Biol Chem 279:7591-7597.
50. 3 endocrine system to mediate genomic and rapid responses. Steroids 66:147-158.
51. 3 is present in an intestinal caveolae membrane fraction. Biochem Biophys Res Commun 298:414-419.
52. Norman A, Mizwicki M, Norman D. 2004. Steroid-hormone rapid actions. Membrane receptors and a conformational ensemble model. Nat Rev Drug Discov 3:27-41.
53. 3 receptor. Canc Res 62:7050-7058.
54. 3 induces vascular smooth muscle cell migration via activation of phosphatidylinositol 3-kinase. Circ Res 91:17-24.
55. 3 modulated growth plate chondrocyte physiology via protein kinase C-dependent phosphorylation of extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase. Endocrinology 143:2775-2786.
56. 3 regulates chondrocyte matrix vesicle protein kinase C (PKC) directly via G-protein-dependent mechanisms and indirectly via incorporation of PKC during matrix vesicle biogenesis. J Biol Chem 277:11828-11837.
57. 3. J Biol Chem 270:6639-6643.
58. 3 in promyelocytic NB4 leukaemia cells. A structure-function study. Endocrinology 139:457-465.
59. 3, retinoic acid and TPA augment forskolin-induced cyclic AMP accumulation in the absence of altered isozyme expression. Arch Dermatol Res 290:407-412.
60. 3 receptor antagonists. Mol Pharm 59:1478-1485.
61. 3 stimulates adenylyl cyclase pathway in muscle cells by a GTP-dependent mechanism which presumably involved phosphorylation Gαi. 234:125-128.
62. Xiao J, Ghosn C, Hinchman C, Forbes C, Wang J, Snider R, Cordey A, Zhao Y, Chandraratna R. 2003. Adenomatous polyposis coli (APC)-independent regulation of catenin degradation via a retinoid X receptor-mediated pathway. J Biol Chem 278:29954-29962.
63. 3 regulated keratinocyte differentiation. Steroids 66:339-345.
64. 3 and androgens. J Steroid Biochem Molec Biol 86:393-397.
65. Yoshizawa T, Handa Y, Uematsu Y, Takeda S, Sekine Y, Yoshihara Y, Kawakami T, Arioka K, Sato H, Uchiyama Y, Masushige S, Fukamizu A, Matsumoto T, Kato M. 1997. Mice lacking the vitamin D receptor exhibit impaired bone formation uterine hypoplasia and growth retardation after weaning. Nat Genet 16:391-396.
66. 3 of whole cell chloride currents in osteoblastic ROS 17/2.8 cells: A structure-function study. J Biol Chem 272:22617-22622.
67. 3 rapid modulation of three ion channel activities in osteoblasts. Bone 33:71-79.
68. 3 and their physiological significance in osteoblasts. Steroids 69:561-565.
69. 3 requires presence of a functional vitamin D nuclear receptor. Proc Natl Acad Sci USA 101:1589-1594.