Electrical responses to 1α,25(OH)2-Vitamin D3 and their physiological significance in osteoblasts

Steroids

Volumn 69, Issue 8-9, 2004, Pages 561-565

  Zanello, Laura P ^a   Norman, Anthony W ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

1 ,25(OH)2 Vitamin D3; Ion channels; Osteoblasts; Secretion; Steroid

Indexed keywords

CALCITRIOL; ION CHANNEL; VITAMIN D RECEPTOR; CALCITRIOL RECEPTOR;

ANIMAL CELL; ANIMAL CELL CULTURE; CELL ISOLATION; CELL MEMBRANE; CELL SECRETION; CONFERENCE PAPER; CONTROLLED STUDY; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; EXOCYTOSIS; KNOCKOUT MOUSE; MOUSE; NONHUMAN; OSTEOBLAST; RAT; WILD TYPE; ANIMAL; ARTICLE; DRUG EFFECT; GENETIC TRANSCRIPTION; MOUSE MUTANT; PHYSIOLOGY; SECRETION; SIGNAL TRANSDUCTION;

ANIMALS; CALCITRIOL; ELECTROPHYSIOLOGY; EXOCYTOSIS; ION CHANNELS; MICE; MICE, KNOCKOUT; OSTEOBLASTS; RECEPTORS, CALCITRIOL; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC;

EID: 3543029249     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2004.05.003     Document Type: Conference Paper

References (22)

1. Aubin JE, Heersche JNM. In: Feldman D, Glorieux FH, Pike JW, editors. Vitamin D and osteoblasts. 1997. p. 313-28.
2. 3-induced calcium binding protein in bone tissue. Science. 202:1978;70-71
3. 3 on bone. Am J Physiol. 238:1980;494-498
4. Norman AW. Bone and the Vitamin D endocrine system. In: Urist MR, editor. Fundamental and Clinical Bone Physiology. J.B. Lippincott Co.; 1980. p. 242-67.
5. Suda T., Ueno Y., Fujii K., Shinki T. Vitamin D and bone. J Cell Biochem. 88:2003;259-266
6. 3 effects on collagen and DNA synthesis in periosteum and periosteum-free calvaria. Bone. 6:1985;457-460
7. Chen J.J., Jin H., Ranly D.M., Sodek J., Boyan B.D. Altered expression of bone sialoproteins in Vitamin D-deficient rBSP2.7Luc transgenic mice. J Bone Min Res. 14:1999;221-229
8. Bouillon R., Okamura W.H., Norman A.W. Structure-function relationships in the Vitamin D endocrine system. Endocr Rev. 16:1995;200-257
9. 3 metabolites modulate dihydropyridine-sensitive calcium currents in clonal rat osteosarcoma cells. J Biol Chem. 264:1989;20265-20274
10. 3-mediated stimulation of outward anionic currents in osteoblast-like ROS 17/2.8 cells. Biochem Biophys Res Commun. 225:1996;551-556
11. 3 of whole cell chloride currents in osteoblastic ROS 17/2.8 cells: a structure-function study. J Biol Chem. 272:1997;22617-22622
12. 3 rapid modulations. Bone. 33:2003;71-79
13. 3 which mediates rapid activation of protein kinase C. J Bone Min Res. 13:1998;1353-1359
14. 3 through regulation of phospholipase A2 activity and activation of protein kinase A. J Biomed Mater Res. 47:1999;139-151
15. Duncan R.L., Akanbi K.A., Farach-Carson M.C. Calcium signals and calcium channels in osteoblastic cells. Sem Nephrol. 18:1998;178-190
16. 3. Steroids. 67:2002;457-466
17. 3 signal response pathways in osteoblasts: cross-talk between genomic and membrane-initiated pathways. Am J Kidney Dis. 31:1998;729-742
18. Zanello L.P., Norman A.W. Rapid modulation of osteoblasts ion channel responses by 1,25-dihydroxyvitamin D3 requires the presence of a functional Vitamin D nuclear receptor. PNAS. 101:2004;1589-1594
19. Yoshizawa T., Handa Y., Uematsu Y., Takeda S., Sekine K., Yoshihara Y., et al. Mice lacking the Vitamin D receptor exhibit impaired bone formation. Nat Genet. 16:1997;391-396
20. Kallay E., Pietschmann P., Toyokuni S., Bajna E., Hahn P., Mazzucco K., et al. Characterization of a Vitamin D receptor knockout mouse as a model of colorectal hyperproliferation and DNA damage. Carcinogenesis. 22:2001;1429-1435
21. Hamill O.P., Marty A., Neher E., Sakmann B., Sigworth F. Improved path-clamp techniques for high resolution current recording from cells and from cell-free membrane patches. Pflugers Archives. 381:1981;85-100
22. Klyachko V.A., Jackson M.B. Capacitance steps and fusion pores of small and large-dense-core vesicles in nerve terminals. Nature. 418:2003;89-92