Parathyroid hormone (PTH) and hematopoiesis: New support for some old observations

Journal of Cellular Biochemistry

Volumn 96, Issue 2, 2005, Pages 278-284

  Whitfield, James F ^a  

^a NATIONAL RESEARCH COUNCIL CANADA   (Canada)

Author keywords

catenin; Adenylyl cyclase; Apoptosis; Bone marrow transplants; CFU S (colony forming units spleen); Cyclic AMP; Hematopoiesis; HSC (hematopoietic stem cells); Jagged 1; N cadherin; Notch receptors; PTH (parathyroid hormone); PTHR1 receptor; Stem cell niche

Indexed keywords

ADENYLATE CYCLASE; BETA CATENIN; CALCIUM ION; CALCIUM SENSING RECEPTOR; CYCLIC AMP; EDETIC ACID; JAGGED1; NERVE CELL ADHESION MOLECULE; NOTCH RECEPTOR; PARATHYROID HORMONE; PARATHYROID HORMONE RECEPTOR 1; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; CELL DIFFERENTIATION; COLONY FORMING UNIT S; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL; MOUSE; NONHUMAN; OSTEOBLAST; PARATHYROID GLAND; PRIORITY JOURNAL; RAT; TRABECULAR BONE; X IRRADIATION;

ANIMALS; CHELATING AGENTS; EDETIC ACID; HEMATOPOIESIS; HUMANS; PARATHYROID HORMONE;

BOVINAE; RODENTIA;

EID: 26444461623     PISSN: 07302312     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcb.20526     Document Type: Article

References (57)

1. Becker AJ, McCulloch EA, Siminovitch L, Till JE. 1965. The effect of differing demands for blood cell production on DNA synthesis by hemopoietic colony-forming cells of mice. Blood 26:296-308.
2. Bellido T, Plotkin LI, Davis J, Manolagas SC, Jilka RL. 2001. Protein kinase A-dependent phosphorylation and inactivation of the pro-apoptotic protein Bad mediates the anti-apoptotic effect of PTH on osteoblastic cells. J Bone Miner Res 16:S203.
3. Bertho JM, Mathieu E, Lauby A, Frick J, Demarquay C, Gourmelon P, Gorin NC, Thierry D. 2004. Feasibility and limits of bone marrow mononuclear cell expansion following irradiation. Int J Radiat Biol 80:73-81.
4. Byron JW. 1977. Cyclic nucleotides and the cell cycle of the hematopoietic stem cell. In: Abou-Sabe M, editor. Cyclic nucleotides and the regulation of cell growth. Stroudsburg, Pennsylvania: Dowden, Hutchinson & Ross, Inc., pp 81-93.
5. Calvi LM, Adams GB, Weibrecht KW, Weber JM, Olson DP, Knight MC, Martin RP, Schipani E, Divieti P, Bringhurst FR, Milner LA, Kronenberg HM, Scadden DT. 2003. Osteoblastic cells regulate the haematopoietic stem cell niche. Nature 425:841-846.
6. Chae H-J, Chae S-W, An N-H, Kim J-H, Kim C-W, Yoo S-K, Kim H-H, Lee Z-H, Kim H-R. 2001. Cyclic AMP inhibits nitric oxide-induced apoptosis in human osteoblast: The regulation of caspase-3, -6, -9 and the release of cytochrome c in nitric oxide-induced apoptosis by cAMP. Biol Pharm Bull 24:453-460.
7. Chen XD, Stewart SA, Manolagas SC, Jilka RL. 2004. Dissection of PTH-induced signaling newwork in osteoblastic cells using a novel bioinformatics approach. J Bone Miner Res 19:S76.
8. + cell proliferation and differentiation. Stem Cells 17:273-285.
9. Duncan AW, Rattis FM, DiMascio LN, Congdon KL, Pazianos G, Zhao C, Yoon K, Cook JM, Willert K, Gaiano N, Reya T. 2005. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance. Nature Immunol 6:314-322.
10. Findik D, Song Q, Hidaka H, Lavin M. 1995. Protein kinase A inhibitors enhance radiation-induced apoptosis. J Cell Biochem 57:12-21.
11. Gallien-Lartigue O, Carrez D. 1974. Induction in vitro de la phase S dans les cellules souches multipotentes de la moelle osseuse par l'hormone parathyroïdienne. C R Acad Sc D Paris 278:1765-1768.
12. Garcia-Bermejo L, Pérez C, Vilaboa N, deBlas E, Aller P. 1998. cAMP increasing agents attenuate the generation of apoptosis by etoposide in promonocytic leukemia cells. J Cell Sci 111:637-644.
13. Goud SN. 1999. Effects of sublethal radiation on bone marrow cells: Induction of apoptosis and inhibition of antibody formation. Toxicology 135:69-76.
14. Hastings RH, Araiza F, Burton DW, Bedley M, Deftos LJ. 2004. Parathyroid hormone-related protein regulates apoptosis in lung cancer cells through protein kinase A. Am J Physiol Cell Physiol 287:C1616-1622.
15. Keller G. 1992. Clonal analysis of hematopoletic stem cell development in vivo. Topics Microbiol Immunol 177:41-57.
16. Li M, Wang X, Meintzer MK, Laessig T, Birnbaum MJ, Heidenreich KA. 2000. Cyclic AMP promotes neuronal survival by phosphorylation of glycogen synthase kinase 3β. Mol Cell Biol 20:9356-9363.
17. Lord BI. 1990. The architecture of bone marrow cell populations. Int J Cell Cloning 8:317-331.
18. Lord BI, Testa NG, Hendry JH. 1975. The relative spatial distributions of CFUs and CFUc in the normal mouse femur. Blood 46:65-72.
19. Marie PJ. 2002. Role of N-cadherin in bone formation. J Cell Physiol 190:297-305.
20. Martin MC, Allan LA, Lickrish M, Sampson C, Morrice N, Clarke PR. 2005. Protein kinase A regulates caspase-9 activation by Apaf-1 downstream of cytochrome c. J Biolchem 280:15449-15455.
21. Mason TM, Lord BI, Hendry JH. 1989. The development of spatial distributions of CFU-S and in vitro CFC in femora of mice of different ages. Brit J Haematol 73:455-461.
22. Mithal A, Brown EM. 2003. An overview of extracellular calcium homeostasis and the roles of the CaR in parathyroid and C-cells. In: Chattopadhyay N, Brown EM, editors. Calcium-sensing receptors. Boston: Kluwer Academic Publishers, pp.1-27.
23. Nakorn TN, Traver D, Weissman IL, Akashi K. 2002. Myoerythroid-restricted progenitors are sufficient to confer radioprotection and provide the majority of day 8 CFU-S. J Clin Invest 109:1579-1585.
24. 2+ receptor antagonists that stimulate secretion of parathyroid hormone. J Pharmacol Exp Ther 299:323-331.
25. Nilsson SK, Johnson HM, Coverdale JA. 2001. Spatial localization of the transplanted hemopoietic stem cells: Inferences for the localization of stem cell niches. Blood 97:2293-2299.
26. Peng R, Wang D, Xiong C, Li Y, Gao Y, Wang B, Cui Y, Yang H, Hu W. 1998. The changes and significance of c-kit expression in the irradiated bone marrow of mice. J Environ Pathol Toxicol Oncol 17:129-133.
27. Peng R, Wang D, Wang B, Xia G, Li V, Xiong C, Gao Y, Yang H, Cui Y. 1999. Apoptosis of hematopoietic cells in irradiated mouse bone marrow. J Environ Pathol Toxicol Oncol 18:305-308.
28. Perris AD, Whitfield JF. 1966. Calcium and the control of mitosis in the mammal. Nature 216:150-1351.
29. Perris AD, Whitfield JF. 1971. Calcium homeostasis and erythropoietic control in the rat. Can J Physiol Pharmacol 49:22-35.
30. Perris AD, MacManus JP, Whitfield JF, Weiss LA. 1971. Parathyroid glands and mitotic stimulation in rat bone marrow after hemorrhage. Am J Physiol 220:738-773.
31. Plotkin LI, Bellido T, Ali AA, Fu Q, Gubrij I, McCauley LK, O'Brien CA, Manolagas SC, Jilka RL. 2002. Runx2/Cbfa1 is essential for the anti-apoptotic effect of PTH on osteoblasts. J Bone Miner Res 17:8166.
32. Potts JT, Jr., Tregear GW, Keutmann HT, Niall HD, WSauer R, Deftos LJ, Dawson BF, Hogan ML, Aurbach GD. 1971. Synthesis of a biologically active N-terminal tetratriacontapeptide of parathyroid hormone. Proc Natl Acad Sci USA 68:63-67.
33. Reya T, Duncan AW, Allies L, Domen J, Scherer DC, Willert K, Hintz L, Nussel R, Weissman IL. 2003. A role for Wnt signalling in self-renewal of haematopoietic stem cells. Nature 423:409-414.
34. Rixon RH, Whitfield JF. 1961. The radioprotective action of parathyroid extract. Int J Rad Biol 3:361-367.
35. Rixon RH, Whitfield JF. 1969. The relation between the mitogenic and therapeutic actions of milk and sodium caseinate in X-irradiated mice. Rad Res 40:601-612.
36. Rixon RH, Whitfield JF. 1972. Hypoplasia of the bone marrow in rats following removal of the parathyroid glands. J Cell Physiol 79:343-352.
37. Rixon RH, Whitfield JF, Youdale T. 1958. Increased survival of rats irradiated with X-rays and treated with parathyroid extract. Nature 182:1374.
38. Rixon RH, Whitfield JF, MacManus JP. 1970. Stimulation of mitotic activity in rat bone marrow and thymus by exogenous adenosine 3′,5′-monophosphate (cyclic AMP). Exp Cell Res 63:110-116.
39. Schofield R. 1978. The relationship between the spleen colony-forming cell and haematopoietic stem cell. Blood Cells 4:7-25.
40. Schofield R. 1979. The pluripotent stem cell. Clin Haematol 8:221-237.
41. Selye H. 1932. On the stimulation of new bone formation with parathyroid extract and irradiated ergosterol. Endocrinology 16:547-558.
42. Sowa H, Kaji H, Iu MF, Tsukamoto T, Sugimoto T, Chihara K. 2003. Parathyroid hormone-Smad3 axis exerts anti-apoptotic action and augments anabolic action of transforming growth factor β in osteoblasts. J Biol Chem 278:52240-52252.
43. Staal FJT, Clevers HC. 2005. Wnt signalling and haematopoiesis: A Wnt-Wnt situation. Nature Revs Immunol 5:21-30.
44. Suva LJ, Towler DA, Harada S, Lafage MH, Steuckle S, Rosenblatt M. 1994. Hormonal regulation of osteoblast-derived cadherin expression in vitro and in vivo. J Bone Miner Res 9:S123.
45. Swierenga SHH, MacManus JP, Braceland BM, Youdale T. 1976. Regulation of the primary immune response in vivo by parathyroid hormone. J Immunol 117:1608-1611.
46. Till JE, McCulloch EA. 1961. A direct measurement of the radiation sensitivity of normal mouse bone marrow. Radiat Res 14:1419-1430.
47. Tregear GW, van Rietschoten J, Greene E, Niall HD, Keutmann HT, Parsons JA, O'Riordan JL, Potts JT, Jr. 1974. Solid-phase synthesis of the biologically active N-terminal 1-34 peptide of human parathyroid hormone. Hoppe Seylers Z Physiol Chem 355:415-421.
48. + progenitor cells. Folia Biol 48:51-57.
49. Virdee K, Parone PA, Tolkovsky AM. 2000. Phosphorylation of the pro-apoptotic protein BAD on serine 155, a novel site, contributes to cell survival. Curr Biol 10:1151-1154.
50. Whitfield JF. 2004. Taming psoriatic keratinocytes-PTHs' uses go up another notch. J Cell Biochem 93:251-256.
51. Whitfield JF. 2005a. Growing bone. Georgetown Texas Landes Bioscience, Eureka.com.
52. Whitfield JF. 2005b. Osteogenic PTHs and vascular ossification-Is there a danger for osteoporotics? J Cell Biochem 95:437-444.
53. Whitfield JF. 2005c. Parathyroid hormone and leptin-new peptides, expanding clinical prospects. Exp Opin Invest Drugs 14:251-264.
54. Whitfield JF, Brohée H, Youdale T. 1965. The effect of varying the environmental calcium and phosphate concentrations on nuclear damage in x-irradiated cultures of bone marrow and thymus. European Atomic Energy Community Report EUR 2485.e.
55. Willert K, Brown JB, Danenberg E, Duncan AW, Weismann IL, Reya T, Yates JR, Nusse R. 2003. Wnt proteins are lipid-modified and can act as stem cell growth factors. Nature 423:448-452.
56. Zhang J, Niu C, Yo L, Huang H, He X, Tong W-G, Ross J, Haug J, Johnson T, Feng JQ, Harris S, Wiedmann L, Mishina Y, Li L. 2003. Indentification of the haematopoietic stem cell niche and control of niche size. Nature 425:836-841.
57. Zhu J, Emerson SG. 2004. A new bone to pick: Osteoblasts and haematopoietic stem-cell niche. BioEsaays 26:595-599.