-
1
-
-
0026609559
-
Alternative excitotoxic hypothesis
-
Albin L. and Greenamyre J. T. (1992) Alternative excitotoxic hypothesis. Neurology 42, 733-738.
-
(1992)
Neurology
, vol.42
, pp. 733-738
-
-
Albin, L.1
Greenamyre, J.T.2
-
2
-
-
0343983913
-
3-Nitropropionate, the toxic substance of Indiofera, is a suicide inactivator of succinate dehydrogenase
-
Alston T. A., Mela L. and Bright H. J. (1977) 3-Nitropropionate, the toxic substance of Indiofera, is a suicide inactivator of succinate dehydrogenase. Proc. Natl. Acad. Sci. USA 74, 3767-3771.
-
(1977)
Proc. Natl. Acad. Sci. USA
, vol.74
, pp. 3767-3771
-
-
Alston, T.A.1
Mela, L.2
Bright, H.J.3
-
3
-
-
0031929675
-
Differential diagnosis of parkinsonism with [18F]fluorodeoxyglucose and PET
-
Antonini A., Kazumata K., Feigin A., Mandel F., Dhawan V., Margouleff C. and Eidelberg D. (1998) Differential diagnosis of parkinsonism with [18F]fluorodeoxyglucose and PET. Mov. Disord. 13, 268-274.
-
(1998)
Mov. Disord.
, vol.13
, pp. 268-274
-
-
Antonini, A.1
Kazumata, K.2
Feigin, A.3
Mandel, F.4
Dhawan, V.5
Margouleff, C.6
Eidelberg, D.7
-
4
-
-
0026584524
-
Does impairment of energy metabolism result in exitotoxic neural death in neurodegenerative illness
-
Beal M. F. (1992) Does impairment of energy metabolism result in exitotoxic neural death in neurodegenerative illness. Ann. Neurol. 31, 119-130.
-
(1992)
Ann. Neurol.
, vol.31
, pp. 119-130
-
-
Beal, M.F.1
-
5
-
-
0032504710
-
Mitochondrial dysfunction in neurodegenerative diseases
-
Beal M. F. (1998) Mitochondrial dysfunction in neurodegenerative diseases. Biochim. Biophys. Acta 1366, 211-223.
-
(1998)
Biochim. Biophys. Acta
, vol.1366
, pp. 211-223
-
-
Beal, M.F.1
-
6
-
-
0027433553
-
Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid
-
Beal M. F., Brouillet E., Jenkins B. G., Ferrante R. J., Kowall N. W., Miller J. M., Storey E., Srivastava R., Rosen B. R. and Hyman B. T. (1993) Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid. J. Neurochem. 13, 4181-4192.
-
(1993)
J. Neurochem.
, vol.13
, pp. 4181-4192
-
-
Beal, M.F.1
Brouillet, E.2
Jenkins, B.G.3
Ferrante, R.J.4
Kowall, N.W.5
Miller, J.M.6
Storey, E.7
Srivastava, R.8
Rosen, B.R.9
Hyman, B.T.10
-
7
-
-
0033681149
-
Chronic systemic pesticide exposure reproduces features of Parkinson's disease
-
Betarbet R., Sherer T. B., MacKenzie G., Garcia-Osuna M., Panov A. V. and Greenamyre J. T. (2000) Chronic systemic pesticide exposure reproduces features of Parkinson's disease. Nat. Neurosci. 3, 1301-1306.
-
(2000)
Nat. Neurosci.
, vol.3
, pp. 1301-1306
-
-
Betarbet, R.1
Sherer, T.B.2
MacKenzie, G.3
Garcia-Osuna, M.4
Panov, A.V.5
Greenamyre, J.T.6
-
8
-
-
0035854087
-
Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat
-
Blum D., Gall D., Cuvelier L. and Schiffinann S. N. (2001) Topological analysis of striatal lesions induced by 3-nitropropionic acid in the Lewis rat. Neuroreport 12, 1769-1772.
-
(2001)
Neuroreport
, vol.12
, pp. 1769-1772
-
-
Blum, D.1
Gall, D.2
Cuvelier, L.3
Schiffinann, S.N.4
-
9
-
-
0031400272
-
Hyperactivity and hypoacfivity in a rat model of Huntington's disease: The systemic 3-nitropropionic acid model
-
Borlongan C., Koutouzis T. K., Freeman T. B., Hauser R. A., Cahill D. W. and Sanberg P. R. (1997) Hyperactivity and hypoacfivity in a rat model of Huntington's disease: the systemic 3-nitropropionic acid model. Brain Res. Protoc. 1, 253-257.
-
(1997)
Brain Res. Protoc.
, vol.1
, pp. 253-257
-
-
Borlongan, C.1
Koutouzis, T.K.2
Freeman, T.B.3
Hauser, R.A.4
Cahill, D.W.5
Sanberg, P.R.6
-
10
-
-
0021883670
-
Regional mitochondrial respiratory activity in Huntington's disease brain
-
Brennan W. A. J., Bird E. D. and Aprille J. R. (1985) Regional mitochondrial respiratory activity in Huntington's disease brain. J. Neurochem. 44, 1948-1950.
-
(1985)
J. Neurochem.
, vol.44
, pp. 1948-1950
-
-
Brennan, W.A.J.1
Bird, E.D.2
Aprille, J.R.3
-
11
-
-
0031914584
-
Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat
-
Brouillet E., Guyot M. C., Mittoux V., Altaire S., Conde F., Palfi S. and Hantraye P. (1998) Partial inhibition of brain succinate dehydrogenase by 3-nitropropionic acid is sufficient to initiate striatal degeneration in rat. J. Neurochem. 70, 794-805.
-
(1998)
J. Neurochem.
, vol.70
, pp. 794-805
-
-
Brouillet, E.1
Guyot, M.C.2
Mittoux, V.3
Altaire, S.4
Conde, F.5
Palfi, S.6
Hantraye, P.7
-
12
-
-
0025854669
-
PET and MR studies of experimental focal stroke
-
Brownell A.-L., Kano M., McKinstry R. C., Moskowitz M. A., Rosen B. R. and Brownell G. L. (1991) PET and MR studies of experimental focal stroke. J. Comput. Assist. Tomogr. 15, 376-380.
-
(1991)
J. Comput. Assist. Tomogr.
, vol.15
, pp. 376-380
-
-
Brownell, A.-L.1
Kano, M.2
McKinstry, R.C.3
Moskowitz, M.A.4
Rosen, B.R.5
Brownell, G.L.6
-
13
-
-
0032449477
-
Dopaminergic modulation of early signs of excitotoxicity in visualized rat neostriatal neurons
-
Cepeda C., Colwell C. S., Itri J. N., Gruen E. and Levine M. S. (1998) Dopaminergic modulation of early signs of excitotoxicity in visualized rat neostriatal neurons. Eur. J. Neurosci. 10, 4391-4397.
-
(1998)
Eur. J. Neurosci.
, vol.10
, pp. 4391-4397
-
-
Cepeda, C.1
Colwell, C.S.2
Itri, J.N.3
Gruen, E.4
Levine, M.S.5
-
14
-
-
0033343644
-
Development of a small animal PET imaging device with resolution approaching 1mm
-
Correia J., Burnham C., Kaufman D. and Fischman A. (1999) Development of a small animal PET imaging device with resolution approaching 1mm. IEEE Trans. Nucl. Sci. 46, 631-635.
-
(1999)
IEEE Trans. Nucl. Sci.
, vol.46
, pp. 631-635
-
-
Correia, J.1
Burnham, C.2
Kaufman, D.3
Fischman, A.4
-
15
-
-
0034068954
-
Early N-acetylaspartate depletion is a marker of neuronal dysfunction in rats and primates chronically treated with the mitochondrial toxin 3-nitropropionic acid
-
Dautry C., Vaufrey F., Brouillet E., Bizat N., Henry P. G., Conde F., Bloch G. and Hantraye P. (2000) Early N-acetylaspartate depletion is a marker of neuronal dysfunction in rats and primates chronically treated with the mitochondrial toxin 3-nitropropionic acid. J. Cereb. Blood Flow Metab. 20, 789-799.
-
(2000)
J. Cereb. Blood Flow Metab.
, vol.20
, pp. 789-799
-
-
Dautry, C.1
Vaufrey, F.2
Brouillet, E.3
Bizat, N.4
Henry, P.G.5
Conde, F.6
Bloch, G.7
Hantraye, P.8
-
16
-
-
0031906152
-
Asymmetry of basal gan glia glucose metabolism and dopa responsiveness in parkinsonism
-
Dethy S., van Blercom N., Damhaut P., Wikler D., Hildebrand J. and Goldman S. (1998) Asymmetry of basal gan glia glucose metabolism and dopa responsiveness in parkinsonism. Mov. Disord. 13, 275-280.
-
(1998)
Mov. Disord.
, vol.13
, pp. 275-280
-
-
Dethy, S.1
Van Blercom, N.2
Damhaut, P.3
Wikler, D.4
Hildebrand, J.5
Goldman, S.6
-
17
-
-
0023195431
-
Positron emission tomography using [18F]fluorodeoxyglucose in brain tumors. A powerful diagnostic and prognostic tool
-
Di Chiro G. (1987) Positron emission tomography using [18F]fluorodeoxyglucose in brain tumors. A powerful diagnostic and prognostic tool. Invest. Radiol. 22, 360-371.
-
(1987)
Invest. Radiol.
, vol.22
, pp. 360-371
-
-
Di Chiro, G.1
-
18
-
-
0028353005
-
Cortical glucose metabolism in Parkinson's disease without dementia
-
Eberling J., Richardson B. C., Reed B. R., Wolfe N. and Jagust W. J. (1994) Cortical glucose metabolism in Parkinson's disease without dementia. Neurobiol. Aging 15, 329-335.
-
(1994)
Neurobiol. Aging
, vol.15
, pp. 329-335
-
-
Eberling, J.1
Richardson, B.C.2
Reed, B.R.3
Wolfe, N.4
Jagust, W.J.5
-
19
-
-
9244234394
-
Regional metabolic correlates of surgical outcome following unilateral pallidotomy for Parkinson's disease
-
Eidelberg D., Moeller J. R., Ishikawa T. et al. (1996) Regional metabolic correlates of surgical outcome following unilateral pallidotomy for Parkinson's disease. Ann. Neurol. 39, 452-459.
-
(1996)
Ann. Neurol.
, vol.39
, pp. 452-459
-
-
Eidelberg, D.1
Moeller, J.R.2
Ishikawa, T.3
-
20
-
-
0035211142
-
Perseverative behavior underlying attentional set-shifting deficit in rats chronically treated with the neurotoxin 3-nitropropionic acid
-
El Massioui N., Ouary S., Cheruel F., Hantraye P. and Brouillet E. (2001) Perseverative behavior underlying attentional set-shifting deficit in rats chronically treated with the neurotoxin 3-nitropropionic acid. Exp. Neurol. 172, 172-181.
-
(2001)
Exp. Neurol.
, vol.172
, pp. 172-181
-
-
El Massioui, N.1
Ouary, S.2
Cheruel, F.3
Hantraye, P.4
Brouillet, E.5
-
21
-
-
0029923617
-
Energy and glutamate dependency of 3-nitropropionic acid neurotoxicity in culture
-
Fink S. L., Ho D. Y. and Sapolsky R. M. (1996) Energy and glutamate dependency of 3-nitropropionic acid neurotoxicity in culture. Exp. Neurol. 138, 298-304.
-
(1996)
Exp. Neurol.
, vol.138
, pp. 298-304
-
-
Fink, S.L.1
Ho, D.Y.2
Sapolsky, R.M.3
-
22
-
-
0001954415
-
SAAM II: Simulation, analysis and modeling software
-
Foster D. M. (1994) SAAM II: simulation, analysis and modeling software. BMES Bull. 18, 19-21.
-
(1994)
BMES Bull.
, vol.18
, pp. 19-21
-
-
Foster, D.M.1
-
23
-
-
0037088935
-
The mitochondrial toxin 3-nitropropionic acid induces striatal neurodegeneration via a c-Jun N-terminal kinase/c-Jun module
-
Garcia M., Vanhoutte P., Pages C., Besson M. J., Brouillet E. and Caboche J. (2002) The mitochondrial toxin 3-nitropropionic acid induces striatal neurodegeneration via a c-Jun N-terminal kinase/c-Jun module. J. Neurosci. 22, 2174-2184.
-
(2002)
J. Neurosci.
, vol.22
, pp. 2174-2184
-
-
Garcia, M.1
Vanhoutte, P.2
Pages, C.3
Besson, M.J.4
Brouillet, E.5
Caboche, J.6
-
24
-
-
0034088054
-
Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: Preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid beta-peptide, iron, and 3-nitropropionic acid
-
Guo Z., Ersoz A., Butterfield D. A. and Mattson M. P. (2000) Beneficial effects of dietary restriction on cerebral cortical synaptic terminals: preservation of glucose and glutamate transport and mitochondrial function after exposure to amyloid beta-peptide, iron, and 3-nitropropionic acid. J. Neurochem. 75, 314-320.
-
(2000)
J. Neurochem.
, vol.75
, pp. 314-320
-
-
Guo, Z.1
Ersoz, A.2
Butterfield, D.A.3
Mattson, M.P.4
-
25
-
-
0030997707
-
Quantifiable bradykinesia, gait abnormalities and Huntington's disease-like striatal lesions in rats chronically treated with 3-nitropropionic acid
-
Guyot M.-C., Hantraye P., Dolan R., Palfi S., Maziere M. and Brouillet E. (1997) Quantifiable bradykinesia, gait abnormalities and Huntington's disease-like striatal lesions in rats chronically treated with 3-nitropropionic acid. Neuroscience 79, 45-56.
-
(1997)
Neuroscience
, vol.79
, pp. 45-56
-
-
Guyot, M.-C.1
Hantraye, P.2
Dolan, R.3
Palfi, S.4
Maziere, M.5
Brouillet, E.6
-
26
-
-
0033978780
-
FDG PET measurement of the proliferative potential of non-small cell lung cancer
-
Higashi K., Ueda Y., Yagishita M., Arisaka Y., Sakurai A., Ogushi M., Seki H., Nambu Y., Tonami H. and Yamamoto I. (2000) FDG PET measurement of the proliferative potential of non-small cell lung cancer. J. Nucl. Med. 41, 85-92.
-
(2000)
J. Nucl. Med.
, vol.41
, pp. 85-92
-
-
Higashi, K.1
Ueda, Y.2
Yagishita, M.3
Arisaka, Y.4
Sakurai, A.5
Ogushi, M.6
Seki, H.7
Nambu, Y.8
Tonami, H.9
Yamamoto, I.10
-
27
-
-
0027480960
-
A novel gene containing a trinucleotide repeat is expanded and unstable on Huntington's disease chromosomes
-
Huntington's Disease Collaborative Group (1993) A novel gene containing a trinucleotide repeat is expanded and unstable on Huntington's disease chromosomes. Cell 72, 971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
28
-
-
0029866972
-
Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging
-
Jenkins B. G., Brouillet E., Chen Y. C., Storey E., Schultz J. B., Kirschner P., Beal M. F. and Rosen B. R. (1996) Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging. J. Cereb. Blood Flow Metab. 16, 450-461.
-
(1996)
J. Cereb. Blood Flow Metab.
, vol.16
, pp. 450-461
-
-
Jenkins, B.G.1
Brouillet, E.2
Chen, Y.C.3
Storey, E.4
Schultz, J.B.5
Kirschner, P.6
Beal, M.F.7
Rosen, B.R.8
-
29
-
-
0033945809
-
Dopamine toxicity following long term exposure to low doses of 3-nitropropionic acid (3-NP) in rats
-
Johnson J., Robinson B. L., Ali S. F. and Binienda Z. (2000) Dopamine toxicity following long term exposure to low doses of 3-nitropropionic acid (3-NP) in rats. Toxicol. Lett. 116, 113-118.
-
(2000)
Toxicol. Lett.
, vol.116
, pp. 113-118
-
-
Johnson, J.1
Robinson, B.L.2
Ali, S.F.3
Binienda, Z.4
-
30
-
-
0035116104
-
Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum
-
Kim G. W. and Chan P. H. (2001) Oxidative stress and neuronal DNA fragmentation mediate age-dependent vulnerability to the mitochondrial toxin, 3-nitropropionic acid, in the mouse striatum. Neurobiol. Dis. 8 (1 Part B), 114-126.
-
(2001)
Neurobiol. Dis.
, vol.8
, Issue.1 PART B
, pp. 114-126
-
-
Kim, G.W.1
Chan, P.H.2
-
31
-
-
0033923563
-
Temporal changes of cerebral metabolites and straital lesions in acute 3-nitropropionic acid intoxication in the rat
-
Lee W.-T., Lee C.-S., Pan Y.-L. and Chang C. (2000) Temporal changes of cerebral metabolites and straital lesions in acute 3-nitropropionic acid intoxication in the rat. Magn. Reson. Med. 44, 29-34.
-
(2000)
Magn. Reson. Med.
, vol.44
, pp. 29-34
-
-
Lee, W.-T.1
Lee, C.-S.2
Pan, Y.-L.3
Chang, C.4
-
32
-
-
0026357457
-
3-Nitropropionic acid - Exogenous animal neurotoxin and possible human striatal toxin
-
Ludolph A. C., He F., Spencer P. S., Hammerstad J. and Sabri M. (1991) 3-nitropropionic acid - Exogenous animal neurotoxin and possible human striatal toxin. Can. J. Neurol. Sci. 18, 492-498.
-
(1991)
Can. J. Neurol. Sci.
, vol.18
, pp. 492-498
-
-
Ludolph, A.C.1
He, F.2
Spencer, P.S.3
Hammerstad, J.4
Sabri, M.5
-
33
-
-
0034127284
-
Major strain differences in response to chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid in rats: Implications for neuroprotection studies
-
Ouary S., Bizat N., Altairac S., Menetrat H., Mittoux V., Conde F., Hantraye P. and Brouillet E. (2000) Major strain differences in response to chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid in rats: implications for neuroprotection studies. Neuroscience 97, 521-530.
-
(2000)
Neuroscience
, vol.97
, pp. 521-530
-
-
Ouary, S.1
Bizat, N.2
Altairac, S.3
Menetrat, H.4
Mittoux, V.5
Conde, F.6
Hantraye, P.7
Brouillet, E.8
-
34
-
-
0025260716
-
Local cerebral glucose utilization in monkeys with hemiparkinsonism induced by intracarotid infusion of the neurotoxin MPTP
-
Palombo E., Porrino L. J., Bankiewicz K. S., Crane A. M., Sokoloff L. and Kopin I. J. (1990) Local cerebral glucose utilization in monkeys with hemiparkinsonism induced by intracarotid infusion of the neurotoxin MPTP. J. Neurosci. 10, 860-869.
-
(1990)
J. Neurosci.
, vol.10
, pp. 860-869
-
-
Palombo, E.1
Porrino, L.J.2
Bankiewicz, K.S.3
Crane, A.M.4
Sokoloff, L.5
Kopin, I.J.6
-
35
-
-
0030946503
-
Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: Acute excitotoxic necrosis and delayed apoptosis
-
Pang Z. and Geddes J. W. (1997) Mechanisms of cell death induced by the mitochondrial toxin 3-nitropropionic acid: acute excitotoxic necrosis and delayed apoptosis. J. Neurosci. 17, 3064-3073.
-
(1997)
J. Neurosci.
, vol.17
, pp. 3064-3073
-
-
Pang, Z.1
Geddes, J.W.2
-
36
-
-
0018582265
-
Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18)2-fluoro-2-deoxy-D-glucose: Validation of method
-
Phelps M. E., Huang S. C., Hoffman E. J., Selin C., Sokoloff L. and Kuhl D. (1979) Tomographic measurement of local cerebral glucose metabolic rate in humans with (F-18)2-fluoro-2-deoxy-D-glucose: Validation of method. Ann. Neurol. 6, 371-388.
-
(1979)
Ann. Neurol.
, vol.6
, pp. 371-388
-
-
Phelps, M.E.1
Huang, S.C.2
Hoffman, E.J.3
Selin, C.4
Sokoloff, L.5
Kuhl, D.6
-
37
-
-
0032402138
-
Dopamine modulates the susceptibility of striatal neurons to 3-nitropropionic acid in the rat model of Huntington's disease
-
Reynolds D. S., Carter R. J. and Morton J. (1998) Dopamine modulates the susceptibility of striatal neurons to 3-nitropropionic acid in the rat model of Huntington's disease. J. Neurosci. 18, 10116-10127.
-
(1998)
J. Neurosci.
, vol.18
, pp. 10116-10127
-
-
Reynolds, D.S.1
Carter, R.J.2
Morton, J.3
-
38
-
-
0017368491
-
The (C-14) deoxy glucose method for the measurement of local cerebral glucose utilization: Theory, procedure, the normal values in the conscious and anesthetized albino rat
-
Sokoloff L., Reivich M., Kennedy C., Des Rosiers M. H., Patlak C. S., Pettigrew K. D., Sakurada D. and Shinohara M. (1977) The (C-14) deoxy glucose method for the measurement of local cerebral glucose utilization: Theory, procedure, the normal values in the conscious and anesthetized albino rat. J. Neurochem. 28, 897-916.
-
(1977)
J. Neurochem.
, vol.28
, pp. 897-916
-
-
Sokoloff, L.1
Reivich, M.2
Kennedy, C.3
Des Rosiers, M.H.4
Patlak, C.S.5
Pettigrew, K.D.6
Sakurada, D.7
Shinohara, M.8
-
39
-
-
0033930553
-
3-Nitropropionic acid in organotypic striatal and cortico-striatal slice cultures is dependent on glucose and glutamate
-
Storgaard J., Kornblit B. T., Zimmer J., Bert J. and Gramsbergen P. (2000) 3-nitropropionic acid in organotypic striatal and cortico-striatal slice cultures is dependent on glucose and glutamate. Exp. Neurol. 164, 227-235.
-
(2000)
Exp. Neurol.
, vol.164
, pp. 227-235
-
-
Storgaard, J.1
Kornblit, B.T.2
Zimmer, J.3
Bert, J.4
Gramsbergen, P.5
-
40
-
-
0033379783
-
3-Nitropropionic acid induces a spectrum of Huntington's disease-like neuropathology in rat striatum
-
Vis J. C., Verbeek M. M., De Waal R. M., Ten Donkelaar H. J. and Kremer H. P. (1999) 3-Nitropropionic acid induces a spectrum of Huntington's disease-like neuropathology in rat striatum. Neuropathol. Appl. Neurobiol. 25, 513-521.
-
(1999)
Neuropathol. Appl. Neurobiol.
, vol.25
, pp. 513-521
-
-
Vis, J.C.1
Verbeek, M.M.2
De Waal, R.M.3
Ten Donkelaar, H.J.4
Kremer, H.P.5
-
42
-
-
0021346318
-
Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
-
Wyllie A. H., Morris R. G., Smith A. L. and Dunlop D. (1984) Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J. Pathol. 142, 67-77.
-
(1984)
J. Pathol.
, vol.142
, pp. 67-77
-
-
Wyllie, A.H.1
Morris, R.G.2
Smith, A.L.3
Dunlop, D.4
|