Major strain differences in response to chronic systemic administration of the mitochondrial toxin 3-nitropropionic acid in rats: Implications for neuroprotection studies

Neuroscience

Volumn 97, Issue 3, 2000, Pages 521-530

  Ouary, S ^a   Bizat, N ^a   Altairac, S ^a   Menetrat H ^a   Mittoux, V ^a   Conde F ^a   Hantraye, P ^a   Brouillet, E ^a  

^a SERVICE HOSPITALIER FRÉDÉRIC JOLIOT   (France)

Author keywords

Huntington; Mitochondrial toxin; Neurodegeneration; Strain dependence; Striatum

Indexed keywords

3 NITROPROPIONIC ACID; SUCCINATE DEHYDROGENASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN INJURY; CONTROLLED STUDY; DNA STRAND BREAKAGE; HISTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MALE; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; RAT; STRAIN DIFFERENCE; STRESS; SURVIVAL;

ANIMALS; BEHAVIOR, ANIMAL; CELL SURVIVAL; CONVULSANTS; DISEASE MODELS, ANIMAL; DRUG ADMINISTRATION ROUTES; DRUG ADMINISTRATION SCHEDULE; DYSKINESIA, DRUG-INDUCED; HUNTINGTON DISEASE; MALE; MITOCHONDRIA; NEOSTRIATUM; NERVE DEGENERATION; NEUROTOXINS; NITRO COMPOUNDS; PROPIONIC ACIDS; RATS; RATS, INBRED F344; RATS, INBRED LEW; RATS, SPRAGUE-DAWLEY; STRESS; SUCCINATE DEHYDROGENASE;

EID: 0034127284     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4522(00)00020-8     Document Type: Article

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