Uptake of host cell transforming growth factor-β by Trypanosoma cruzi amastigotes in cardiomyocytes: Potential role in parasite cycle completion

American Journal of Pathology

Volumn 167, Issue 4, 2005, Pages 993-1003

  Waghabi, Mariana C ^a   Keramidas, Michelle ^c   Bailly, Sabine ^c   Degrave, Wim ^a   Mendonça Lima, Leila ^a   Soeiro, Maria De Nazaré C ^a   Meirelles, Maria De Nazareth L ^a   Paciornik, Sidnei ^b   Araújo Jorge, Tania C ^a   Feige, Jean Jacques ^c,d  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b PONTIFICAL CATHOLIC UNIVERSITY OF RIO DE JANEIRO   (Brazil)

^c INSERM   (France)

^d CEA GRENOBLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; TRANSFORMING GROWTH FACTOR BETA;

AMASTIGOTE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHAGAS DISEASE; CONTROLLED STUDY; CYTOPLASM; ELECTRON MICROSCOPY; EMBRYO; GENOME; HEART MUSCLE CELL; HOST PARASITE INTERACTION; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITE DEVELOPMENT; PARASITE VIRULENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STAINING; TRYPANOSOMA CRUZI;

EID: 26244462870     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9440(10)61189-3     Document Type: Article

References (38)

1. Umezawa ES, Stolf AM, Corbett CE, Shikanai-Yasuda MA: Chagas disease. Lancet 2001, 357:797-799
2. De Souza W: From the cell biology to the development of new chemotherapeutic approaches against trypanosomatids: dreams and reality. Kinetoplastid Biol Dis 2002, 1:3
3. Rossi MA, Bestetti RB: The challenge of chagasic cardiomyopathy. The pathologic roles of autonomic abnormalities, autoimmune mechanisms and microvascular changes, and therapeutic implications. Cardiology 1995, 86:1-7
4. Higuchi ML, Fukasawa S, De Brito T, Parzianello LC, Bellotti G, Ramires JA: Different microcirculatory and interstitial matrix patterns in idiopathic dilated cardiomyopathy and Chagas' disease: a three dimensional confocal microscopy study. Heart 1999, 82:279-285
5. Araujo-Jorge TC, Waghabi MC, Hasslocher-Moreno AM, Xavier SS, Higuchi ML, Keramidas M, Bailly S, Feige JJ: Implication of transforming growth factor-beta1 in Chagas disease myocardiopathy. J Infect Dis 2002, 186:1823-1828
6. Roberts AB, Sporn MB: The transforming growth factor-βs. Peptide Growth Factors and Their Receptors. Edited by Sporn MB, Roberts AB. Berlin, Springer-Verlag, 1991, pp 419-472
7. Massague J: TGF-beta signal transduction. Annu Rev Biochem 1998, 67:753-791
8. Miyazono K: TGF-beta signaling by Smad proteins. Cytokine Growth Factor Rev 2000, 11:15-22
9. Gleizes PE, Munger JS, Nunes I, Harpel JG, Mazzieri R, Noguera I, Rifkin DB: TGF-beta latency: biological significance and mechanisms of activation. Stem Cells 1997, 15:190-197
10. Waghabi MC, Coutinho CM, Soeiro MN, Pereira MC, Feige JJ, Keramidas M, Cosson A, Minoprio P, Van Leuven F, Araujo-Jorge TC: Increased Trypanosoma cruzi invasion and heart fibrosis associated with high transforming growth factor beta levels in mice deficient in alpha(2)-macroglobulin. Infect Immun 2002, 70:5115-5123
11. Ming M, Ewen ME, Pereira ME: Trypanosome invasion of mammalian cells requires activation of the TGF beta signaling pathway. Cell 1995, 82:287-296
12. Hall BS, Pereira MA: Dual role for transforming growth factor beta-dependent signaling in Trypanosoma cruzi infection of mammalian cells. Infect Immun 2000, 68:2077-2081
13. Silva JS, Twardzik DR, Reed SG: Regulation of Trypanosoma cruzi infections in vitro and in vivo by transforming growth factor beta (TGF-beta). J Exp Med 1991, 174:539-545
14. Zhang L, Tarleton RL: Characterization of cytokine production in murine Trypanosoma cruzi infection by in situ immunocytochemistry: lack of association between susceptibility and type 2 cytokine production. Eur J Immunol 1996, 26:102-109
15. Meirelles MN, de Araujo-Jorge TC, Miranda CF, de Souza W, Barbosa HS: Interaction of Trypanosoma cruzi with heart muscle cells: ultrastructural and cytochemical analysis of endocytic vacuole formation and effect upon myogenesis in vitro. Eur J Cell Biol 1986, 41:198-206
16. Tomlinson S, Vandekerckhove F, Frevert U, Nussenzweig V: The induction of Trypanosoma cruzi trypomastigote to amastigote transformation by low pH. Parasitology 1995, 110:547-554
17. Padgett RW, St. Johnston RD, Gelbart WM: A transcript from a Drosophila pattern gene predicts a protein homologous to the transforming growth factor-beta family. Nature 1987, 325:81-84
18. Ren P, Lim CS, Johnsen R, Albert PS, Pilgrim D, Riddle DL: Control of C. elegans larval development by neuronal expression of a TGF-beta homolog. Science 1996, 274:1389-1391
19. Gomez-Escobar N, Gregory WF, Maizels RM: Identification of tgh-2, a filarial nematode homolog of Caenorhabditis elegans daf-7 and human transforming growth factor beta, expressed in microfilarial and adult stages of Brugia malayi. Infect Immun 2000, 68:6402-6410
20. Laucella SA, Velazquez E, Dasso M, de Titto E: Trypanosoma cruzi and mammalian heart cross-reactive antigens. Acta Trop 1996, 61:223-238
21. Mair G, Shi H, Li H, Djikeng A, Aviles HO, Bishop JR, Falcone FH, Gavrilescu C, Montgomery JL, Santori MI, Stern LS, Wang Z, Ullu E, Tschudi C: A new twist in trypanosome RNA metabolism: cis-splicing of pre-mRNA. Rna 2000, 6:163-169
22. Navarro MC, De Lima AR, Askue J, Contreras VT: Morphological comparison of axenic amastigogenesis of trypomastigotes and metacyclic forms of Trypanosoma cruzi. Mem Inst Oswaldo Cruz 2003, 98:83-91
23. Moses HL, Arteaga CL, Alexandrow MG, Dagnino L, Kawabata M, Pierce Jr DF, Serra R: TGF beta regulation of cell proliferation. Princess Takamatsu Symp 1994, 24:250-263
24. Meyer H, De Souza W: On the fine structure of Trypanososma cruzi in tissue cultures of pigment epithelium from the chick embryo. Uptake of melanin granules by the parasite. J Protozool 1973, 20:590-593
25. Coutinho CM, Cavalcanti GH, van Leuven F, Araujo-Jorge TC: Alpha-2-macroglobulin binds to the surface of Trypanosoma cruzi. Parasitol Res 1997, 83:144-150
26. Huang SS, Ling TY, Tseng WF, Huang YH, Tang FM, Leal SM, Huang JS: Cellular growth inhibition by IGFBP-3 and TGF-beta1 requires LRP-1. FASEB J 2003, 17:2068-2081
27. Cavalier-Smith T: Kingdom protozoa and its 18 phyla. Microbiol Rev 1993, 57:953-994
28. Beall MJ, McGonigle S, Pearce EJ: Functional conservation of Schistosoma mansoni Smads in TGF-beta signaling. Mol Biochem Parasitol 2000, 111:131-142
29. Beall MJ, Pearce EJ: Human transforming growth factor-beta activates a receptor serine/threonine kinase from the intravascular parasite Schistosoma mansoni. J Biol Chem 2001, 276:31613-31619
30. Beall MJ, Pearce EJ: Transforming growth factor-beta and insulin-like signalling pathways in parasitic helminths. Int J Parasitol 2002, 32:399-404
31. Derynck R, Zhang YE: Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 2003, 425:577-584
32. Sowa MP, Coulter LJ, Tait A, Hide G: A novel gene encoding a ras-like GTP-binding protein from Trypanosoma brucei: an evolutionary ancestor of the ras and rap genes of higher eukaryotes? Gene 1999, 230:155-161
33. Nepomuceno-Silva JL, Yokoyama K, de Mello LD, Mendonca SM, Paixao JC, Baron R, Faye JC, Buckner FS, Van Voorhis WC, Gelb MH, Lopes UG: TcRho1, a farnesylated Rho family homologue from Trypanosoma cruzi: cloning, trans-splicing, and prenylation studies. J Biol Chem 2001, 276:29711-29718
34. Ellis J, Sarkar M, Hendriks E, Matthews K: A novel ERK-like, CRK-like protein kinase that modulates growth in Trypanosoma brucei via an autoregulatory C-terminal extension. Mol Microbiol 2004, 53:1487-1499
35. Muller IB, Domenicali-Pfister D, Roditi I, Vassella E: Stage-specific requirement of a mitogen-activated protein kinase by Trypanosoma brucei. Mol Biol Cell 2002, 13:3787-3799
36. Ghansah TJ, Ager EC, Freeman-Junior P, Villalta F, Lima MF: Epidermal growth factor binds to a receptor on Trypanosoma cruzi amastigotes inducing signal transduction events and cell proliferation. J Eukaryot Microbiol 2002, 49:383-390
37. Alexander AD, Villalta F, Lima MF: Transforming growth factor alpha binds to Trypanosoma cruzi amastigotes to induce signaling and cellular proliferation. Infect Immun 2003, 71:4201-4205
38. Waghabi MC, Keramidas M, Feige JJ, Araujo-Jorge TC, Bailly S: Activation of transforming growth factor β by Trypanosoma cruzi. Cell Microbiol 2005, 7:511-517