Hypoxia inducible factor-1α and expression of vascular endothelial growth factor and its receptors in cerebral arteriovenous malformations

Journal of Clinical Neuroscience

Volumn 12, Issue 7, 2005, Pages 794-799

  Ng, Ivan ^a   Tan, Wan Loo ^a   Ng, Puay Yong ^a   Lim, Joyce ^a  

^a TAN TOCK SENG HOSPITAL   (Singapore)

Author keywords

Cerebral arteriovenous malformation; Hypoxia Inducible factor 1; Pathogenesis; Vascular endothelial growth factor

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; VASCULOTROPIN; VASCULOTROPIN RECEPTOR; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3;

ADULT; ARTICLE; BRAIN ARTERIOVENOUS MALFORMATION; BRAIN HEMORRHAGE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MALE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; SURGICAL TECHNIQUE;

ADOLESCENT; ADULT; CHI-SQUARE DISTRIBUTION; FEMALE; GENE EXPRESSION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1; IMMUNOHISTOCHEMISTRY; INTRACRANIAL ARTERIOVENOUS MALFORMATIONS; MALE; MIDDLE AGED; MODELS, NEUROLOGICAL; RECEPTORS, VASCULAR ENDOTHELIAL GROWTH FACTOR; STATISTICS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 26244462183     PISSN: 09675868     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jocn.2005.02.005     Document Type: Article

References (62)

1. J.M. Bruner, R.D. Tien, and R.E. McLendon Tumours of vascular origin D.D. Bigner R.E. McLendon J.M. Bruner Russell and Rubinstein's Pathology of Tumours of the Nervous System Vol. 2 1998 Arnold London 239 293
2. V.R. Challa, D.M. Moody, and W.R. Brown Vascular malformations of the central nervous system J Neuropathl Exp Neurol 54 1995 609 621
3. W.F. McComick The pathology of vascular ("arteriovenous") malformations J Neurosurg 24 1966 807 816
4. T. Hashimoto, R. Mesa-Tejada, and C.M. Quick Abnormal pattern of Tie-2 and vascular endothelial growth factor receptor expression in human cerebral arteriovenous malformations Neurosurgery 47 2000 910 918
5. E. Hatva, J. Jaaskelainen, H. Hirvonen, K. Alitalo, and M. Haltia Tie endothelial cell- specific tyrosine kinase is upregulated in the vasculature of arteriovenous malformations J Neuropathol Exp Neurol 55 1996 1124 1133
6. T. Kilic, M.N. Pamir, S. Kullu, F. Eren, M.M. Ozek, and P.M. Black Expression of structural proteins and angiogenic factors in cerebrovascular anomalies Neurosurgery 46 2000 1179 1191
7. T. Koizumi, T. Shiraishi, N. Hagihara, K. Tabuchi, T. Hayashi, and T. Kawano Expression of vascular endothelial growth factors and their receptors in and around intracranial arteriovenous malformations Neurosurgery 50 2000 117 124
8. J. Li, Y. Gao, and M. Zhao Immunohistochemical study of vascular endothelial growth factor, relative receptors and ligands in vascular endothelial cells of cerebral arteriovenous malformations Zhonghua Wai Ke Zha Zhi 39 2001 675 678
9. R. Uranishi, N.I. Baev, P.Y. Ng, J.H. Kim, and I.A. Awad Expression of endothelial cell angiogenesis receptors in human cerebrovascular malformations Neurosurgery 48 2001 359 367
10. N. Ferrara Vascular endothelial growth factor Trends Cardiovasc Med 3 1993 244 250
11. K.H. Plate, G. Brier, H.A. Weich, and W. Risau Vascular endothelial growth factor is a potential tumour angiogenesis factor in human gliomas in vivo Nature 359 1992 845 848
12. D. Shweiki, A. Itin, D. Soffer, and E. Keshet Vascular endothelial growth factor expression induced by hypoxia may mediate hypoxia-initiated angiogenesis Nature 359 1992 843 845
13. P. Speiser, A.M. Gittelsohn, and A. Patz Studies on diabetic retinopathy III. Influence of diabetes on intramural pericytes Arch Opthal 80 1968 332 337
14. K. Guillemin, and M.A. Krasnow The hypoxic response: huffing and HIFing Cell 89 1997 9 12
15. 2 homeostasis Curr Opin Genet Dev 8 1998 588 594
16. S. Salceda, and J. Caro Hypoxia-inducible factor 1 (HIF-1α ) protein is rapidly degraded by the ubiquitin-proteosome system under normoxic conditions: its stabilization by hypoxia depends upon redox-induced changes J Biol Chem 272 1997 22642 22647
17. C.H. Sutter, E. Laughner, and G.L. Semenza Hypoxia-inducible factor 1a protein expression is controlled by oxygen-regulated ubiquitination that is disrupted by deletions and missense mutations Proc Natl Acad Sci USA 97 2000 4748 4753
18. A. Kader, J.T. Goodrich, W.J. Sonstein, B.M. Stein, P.W. Carmel, and W.J. Michelsen Recurrent cerebral arteriovenous malformations after negative postoperative angiograms J Neurosurg 85 1996 14 18
19. D.H. Duong, W.L. Young, and M.C. Vang Feeding artery pressure and venous drainage patterns are primary determinants of hemorrhage from cerebral arteriovenous malformations Stroke 29 1998 1167 1176
20. S.L. Barnwell, S.F. Ciricillo, V.V. Halbech, M.S. Edwards, and P.H. Cogen Intracerebral arteriovenous fistulas associated with intraparenchymal varix in childhood. Case reports Neurosurgery 26 1990 122 125
21. H.H. Batjer, M.D. Devous, and G.B. Seibert Intracranial arteriovenous malformation: relationships between clinical and radiographic factors and ipsilateral steal severity Neurosurgery 23 1988 322 328
22. W. Feindel, Y.L. Yamamoto, and C.P. Hodge Red cerebral veins and the cerebral steal syndrome. Evidence from flourescein angiography and micro-regional blood flow by radioisotopes during excision of an angioma J Neurosurg 35 1971 167 179
23. W. Hassler, and H. Steinmetz Cerebral hemodynamics in AVM patients. An intraoperative study J Neurosurg 67 1987 822 831
24. J.A. Kuske, and W.A. Kelly Embolisation and reduction of the "steal" syndrome in cerebral arteriovenous malformations J Neurosurg 40 1974 313 321
25. K.G. Peters Vascular endothelial growth factor and the angiopoietins: working together to build a better blood vessel Circ Research 83 1998 342 343
26. L.E. Benjamin, I. Hemo, and E. Keshet A plasticity window for blood vessel remodelling is defined by pericyte coverage of the preformed endothelial network and is regulated by PDGF-B and VEGF Development 125 1998 1591 1598
27. R.E. Friese, and T. Maciag Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction FASEB J 9 1995 919 925
28. K.H. Plate, G. Breier, and W. Risau Molecular mechanisms of developmental and tumour angiogenesis Brain Pathol 4 1994 207 218
29. R.F. Nicosia, S.V. Nicosia, and M. Smith Vascular endothelial growth factor, platelet-derived growth factor and insulin-like growth factor-1 promote rat aortic angiogenesis in vitro Am J Patho 145 1994 1023 1029
30. J.M. Rosentein, N. Mani, W.F. Silverman, and J.M. Krum Patterns of brain angiogenesis after vascular endothelial growth factor administration in vitro and in vivo Proc Natl Acad Sci USA 95 1998 7086 7091
31. T. Alon, I. Hemo, A. Itin, J. Pe'er, J. Stone, and E. Keshet Vascular endothelial growth factor acts as a survival factor for newly formed retinal vessels and has implications for retinopathy of prematurity Nat Med 1 1995 1024 1028
32. B. Millauer, S. Wizigmann-Voos, and H. Schnurch High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis Cell 72 1993 835 846
33. K.G. Peters, C. DeVries, and L.T. Williams Vascular endothelial growth factor receptor expression during embryogenesis and tissue repair suggests a role in endothelial differentiation and blood vessel growth Proc Natl Acad Sci USA 90 1993 8915 8919
34. G.H. Fong, J. Rossant, M. Gertsenstein, and M.L. Breitman Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium Nature 376 1995 66 69 (letter)
35. F. Shalaby, J. Rossant, and T.P. Yamaguchi Failure of blood island formation and vasculogenesis in Flk-1 deficient mice Nature 76 1995 62 66f (letter)
36. P. Carmeliet, Y. Dor, and J.M. Herbert Role of HIF-1a in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis Nature 394 1998 485 490
37. E.A. Pierce, R.L. Avery, E.D. Foley, L.P. Aiello, and L.E. Smith Vascular endothelial growth factor/vascular permeability factor expression in a mouse model of retinal neovascularization Proc Natl Acad Sci USA 92 1995 905 909
38. J. Stone, A. Itin, and T. Alon Development of retinal vasculature is mediated by hypoxia-induced vascular endothelial growth factor (VEGF) expression by neuroglia J Neurosci 15 1995 4738 4747
39. S. Banai, D. Shweiki, A. Pinson, M. Chandra, G. Lazarovici, and E. Keshet Upregulation of vascular endothelial growth factor expression induced by myocardial ischaemia: implications for coronary angiogenesis Cardiovas Res 28 1994 1176 1179
40. L.R. Ment, W.B. Stewart, and R. Fronc Vascular endothelial growth factor mediates reactive angiogenesis in the postnatal developing brain Brain Res Dev Brain Res 100 1997 52 61
41. J.A. Forsythe, B.H. Jiang, and N.V. Iyer Activation of vascular endothelial growth factor gene transcription by hypoxia-inducible factor 1 Mol Cell Biol 16 1996 4604 4613
42. A.P. Levy, N.S. Levy, and M.A. Goldberg Hypoxia-inducible protein binding to vascular endothelial growth factor mRNA and its modulation by the von Hippel-Lindau protein J Biol Chem 271 1996 25492 25497
43. Y. Liu, S.R. Cox, T. Morita, and S. Kourembanas Hypoxia regulates vascular endothelial growth factor gene expression in endothelial cells. Identification of a 5′ enhancer Circ Res 77 1995 638 643
44. G.L. Wang, B.H. Jiang, E.A. Rue, and G.L. Semenza Hypoxia inducible factor 1 is a basic-helix-loop-PAS heterodimer regulated by cellular oxygen tension Proc Natl Acad Sci USA 92 1995 5510 5514
45. G.L. Wang, and G.L. Semenza Purification and characterization of hypoxia-inducible factor 1 J Biol Chem 270 1995 1230 1237
46. B.H. Jiang, J.Z. Zheng, S.W. Leung, R. Roe, and G.L. Semenza Transactivation and inhibitory domains of hypoxia-inducible factor 1a. Modulation of transciptional activity by oxygen tension J Biol Chem 272 1997 19253 19260
47. C.W. Pugh, J.F. O'Rourke, M. Nagao, J.M. Gleadle, and P.J. Ratcliffe Activation of hypoxia-inducible factor-1; definition of regulatory domains within the alpha subunit J Biol Chem 272 1997 11205 11214
48. H.P. Gerber, F. Condorelli, J. Park, and N. Ferrara Differential transcriptional regulation of the two vascular endothelial growth factor genes. Flt-1, but not Flk-1/ KDR, is upregulated by hypoxia J Biol Chem 274 1997 23659 23667
49. M. Bergeron, J.M. Gidday, A.Y. Yu, G.L. Semenza, D.M. Ferriero, and F.R. Sharp Role of hypoxia-inducible factor 1 (HIF-1) in hypoxia-induced ischemic tolerance in neonatal rat brain Ann Neurol 48 2000 285 296
50. E. Berra, D. Roux, and D.E. Richard Hypoxia- inducible factor-1a (HIF-1a) escapes O2-driven proteosomal degradation irrespective of its subcellular localization: nucleus or cytoplasm EMBO 7 2000 615 620
51. 2 in patients with arteriovenous malformations J Cereb Blood Flow Metab 16 1997 1383 1386
52. A.M. Norbash, M.P. Marks, and B. Lane Correlation of pressure measurements with angiographic characteristics predisposing to hemorrhage and steal in cerebral arteriovenous malformations Am J Neuroradiol 15 1994 809 813
53. W.L. Young, A. Kader, and I. Prohovnik Pressure autoregulation is intact after arteriovenous malformation resection Neurosurgery 32 1993 491 496
54. W.L. Young, I. Prohovnik, and E. Ornstein The effect of arteriovenous malformation resection on cerebrovascular reactivity to carbon dioxide Neurosurgery 27 1990 257 267
55. E. Ikeda, M.G. Aachen, G. Breier, and W. Risau Hypoxia-induced transcriptional activation and increased mRNA stability of vascular endothelial growth factor in C6 glioma cells J Biol Chem 270 1995 19761 19766
56. A.P. Levy, N.S. Levy, and M.A. Goldberg Post-transcriptional regulation of vascular endothelial growth factor by hypoxia J Biol Chem 271 1996 2746 2753
57. H.H. Marti, and W. Risau Systemic hypoxia changes the organ-specific distribution of vascular endothelial growth factor and its receptors Proc Natl Acad Sci USA 95 1998 15809 15814
58. T. Akitmoto, H. Liapis, and M.R. Hammerman Microvessel formation from mouse embryonic aortic explants is oxygen and VEGF dependent Am J Physiol 283 2002 R487 R495
59. E. Brogi, G. Schatteman, and T.G. Wu Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression J Clin Invest 97 1996 469 476
60. T.S. Li, K. Hamano, K. Suzuki, H. Ito, N. Zempo, and M. Matsuzaki Improved angiogenic potency by implantation of ex vivo hypoxia prestimulated bone marrow cells in rats Am J Physiol 283 2002 H468 H473
61. B. Vasir, J.C. Jonas, and G.M. Steil Gene expression of VEGF and its receptors Flk-1/KDR and Flt-1 in cultured and transplanted rat islets Transplantation 71 2001 924 935
62. Y.M. Lee, C.H. Jeong, and S.Y. Koo Determination of hypoxic region by hypoxic marker in developing mouse embryos in vivo: a possible signal for vessel development Dev Dyn 220 2001 175 186