메뉴 건너뛰기




Volumn 128, Issue 10, 2005, Pages 2383-2395

Astrogliosis in epilepsy leads to overexpression of adenosine kinase, resulting in seizure aggravation

Author keywords

Adenosine; Adenosine kinase; Astrogliosis; Epilepsy; Transgenic mice

Indexed keywords

ADENOSINE KINASE; ADENOSINE KINASE INHIBITOR; KAINIC ACID; METHYLTESTOSTERONE; UBIQUITIN;

EID: 26044440838     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awh555     Document Type: Article
Times cited : (162)

References (34)
  • 1
    • 13544274000 scopus 로고    scopus 로고
    • Adenosine and epilepsy: From therapeutic rationale to new therapeutic strategies
    • Boison D. Adenosine and epilepsy: from therapeutic rationale to new therapeutic strategies. Neuroscientist 2005; 11: 25-36.
    • (2005) Neuroscientist , vol.11 , pp. 25-36
    • Boison, D.1
  • 2
    • 0032728754 scopus 로고    scopus 로고
    • Seizure suppression in kindled rats by intraventricular grafting of an adenosine releasing synthetic polymer
    • Boison D, Scheurer L, Tseng JL, Aebischer P, Mohler H. Seizure suppression in kindled rats by intraventricular grafting of an adenosine releasing synthetic polymer. Exp Neurol 1999; 160: 164-74.
    • (1999) Exp Neurol , vol.160 , pp. 164-174
    • Boison, D.1    Scheurer, L.2    Tseng, J.L.3    Aebischer, P.4    Mohler, H.5
  • 4
    • 0020639120 scopus 로고
    • Evidence for a substrate cycle between AMP and adenosine in isolated hepatocytes
    • USA
    • Bontemps F, Van den Berghe G, Hers HG. Evidence for a substrate cycle between AMP and adenosine in isolated hepatocytes. Proc Natl Acad Sci USA 1983; 80: 2829-33.
    • (1983) Proc Natl Acad Sci , vol.80 , pp. 2829-2833
    • Bontemps, F.1    Van Den Berghe, G.2    Hers, H.G.3
  • 5
    • 0032956116 scopus 로고    scopus 로고
    • Effects of adenosine receptor agonists and antagonists on audiogenic seizure-sensible DBA/2 mice
    • De Sarro G, De Sarro A, Di Paola ED, Bertorelli R. Effects of adenosine receptor agonists and antagonists on audiogenic seizure-sensible DBA/2 mice. Eur J Pharmacol 1999; 371: 137-45.
    • (1999) Eur J Pharmacol , vol.371 , pp. 137-145
    • De Sarro, G.1    De Sarro, A.2    Di Paola, E.D.3    Bertorelli, R.4
  • 6
    • 0029885802 scopus 로고    scopus 로고
    • Brain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation
    • Delaney SM, Geiger JD. Brain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation. J Neurosci Methods 1996; 64: 151-6.
    • (1996) J Neurosci Methods , vol.64 , pp. 151-156
    • Delaney, S.M.1    Geiger, J.D.2
  • 7
    • 0023280998 scopus 로고
    • 8-Cyclopentyl 1,3-dimethylxanthine prolongs epileptic seizures in rats
    • Dragunow M, Robertson HA. 8-Cyclopentyl 1,3-dimethylxanthine prolongs epileptic seizures in rats. Brain Res 1987; 417: 377-9.
    • (1987) Brain Res , vol.417 , pp. 377-379
    • Dragunow, M.1    Robertson, H.A.2
  • 8
    • 0032613394 scopus 로고    scopus 로고
    • Adenosine and suppression of seizures
    • Dunwiddie TV. Adenosine and suppression of seizures. Adv Neurol 1999; 79: 1001-10.
    • (1999) Adv Neurol , vol.79 , pp. 1001-1010
    • Dunwiddie, T.V.1
  • 9
    • 0034923094 scopus 로고    scopus 로고
    • The role and regulation of adenosine in the central nervous system
    • Dunwiddie TV, Masino SA. The role and regulation of adenosine in the central nervous system. Annu Rev Neurosci 2001; 24: 31-55.
    • (2001) Annu Rev Neurosci , vol.24 , pp. 31-55
    • Dunwiddie, T.V.1    Masino, S.A.2
  • 10
    • 0026459032 scopus 로고
    • Adenosine: A potential mediator of seizure arrest and postictal refractoriness
    • During MJ, Spencer DD. Adenosine: a potential mediator of seizure arrest and postictal refractoriness. Ann Neurol 1992; 32: 618-24.
    • (1992) Ann Neurol , vol.32 , pp. 618-624
    • During, M.J.1    Spencer, D.D.2
  • 11
    • 2442532969 scopus 로고    scopus 로고
    • Endogenous adenosine modulates epilepti-form activity in rat hippocampus in a receptor subtype-dependent manner
    • Etherington LA, Frenguelli BG. Endogenous adenosine modulates epilepti-form activity in rat hippocampus in a receptor subtype-dependent manner. Eur J Neurosci 2004; 19: 2539-50.
    • (2004) Eur J Neurosci , vol.19 , pp. 2539-2550
    • Etherington, L.A.1    Frenguelli, B.G.2
  • 13
    • 33845216127 scopus 로고    scopus 로고
    • Adenosine and neuroprotection
    • Fredholm BB. Adenosine and neuroprotection. Int Rev Neurobiol 1997; 40: 259-80.
    • (1997) Int Rev Neurobiol , vol.40 , pp. 259-280
    • Fredholm, B.B.1
  • 14
    • 0345561561 scopus 로고    scopus 로고
    • Actions of caffeine in the brain with special reference to factors that contribute to its widespread use
    • Fredholm BB, Battig K, Holmen J, Nehlig A, Zvartau EE. Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol Rev 1999; 51: 83-133.
    • (1999) Pharmacol Rev , vol.51 , pp. 83-133
    • Fredholm, B.B.1    Battig, K.2    Holmen, J.3    Nehlig, A.4    Zvartau, E.E.5
  • 15
    • 13844315635 scopus 로고    scopus 로고
    • Actions of adenosine at its receptors in the CNS: Insights from knockouts and drugs
    • Fredholm BB, Chen JF, Masino SA, Vaugeois JM. Actions of adenosine at its receptors in the CNS: insights from knockouts and drugs. Annu Rev Pharmacol Toxicol 2005; 45: 385-412.
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 385-412
    • Fredholm, B.B.1    Chen, J.F.2    Masino, S.A.3    Vaugeois, J.M.4
  • 16
    • 0037478606 scopus 로고    scopus 로고
    • 1 receptor activation in a mouse model of pharmacoresistant epilepsy
    • 1 receptor activation in a mouse model of pharmacoresistant epilepsy. Epilepsia 2003; 44: 877-85.
    • (2003) Epilepsia , vol.44 , pp. 877-885
    • Gouder, N.1    Fritschy, J.M.2    Boison, D.3
  • 17
    • 0842284006 scopus 로고    scopus 로고
    • Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis
    • Gouder N, Scheurer L, Fritschy J-M, Boison D. Overexpression of adenosine kinase in epileptic hippocampus contributes to epileptogenesis. J Neurosci 2004; 24: 692-701.
    • (2004) J Neurosci , vol.24 , pp. 692-701
    • Gouder, N.1    Scheurer, L.2    Fritschy, J.-M.3    Boison, D.4
  • 20
    • 0033995205 scopus 로고    scopus 로고
    • Therapeutic potential of adenosine kinase inhibitors
    • Kowaluk EA, Jarvis MF. Therapeutic potential of adenosine kinase inhibitors. Expert Opin Investig Drugs 2000; 9: 551-64.
    • (2000) Expert Opin Investig Drugs , vol.9 , pp. 551-564
    • Kowaluk, E.A.1    Jarvis, M.F.2
  • 21
    • 0032506161 scopus 로고    scopus 로고
    • Structure of human adenosine kinase at 1.5 angstrom resolution
    • Mathews, II, Erion MD, Ealick SE. Structure of human adenosine kinase at 1.5 angstrom resolution. Biochemistry 1998; 37: 15607-20.
    • (1998) Biochemistry , vol.37 , pp. 15607-15620
    • Mathews, I.I.1    Erion, M.D.2    Ealick, S.E.3
  • 22
    • 13444273445 scopus 로고    scopus 로고
    • Anticonvulsant and antinociceptive actions of novel adenosine kinase inhibitors
    • McGaraughty S, Cowart M, Jarvis MF, Berman RF. Anticonvulsant and antinociceptive actions of novel adenosine kinase inhibitors. Curr Top Med Chem 2005; 5: 43-58.
    • (2005) Curr Top Med Chem , vol.5 , pp. 43-58
    • McGaraughty, S.1    Cowart, M.2    Jarvis, M.F.3    Berman, R.F.4
  • 24
    • 0344198500 scopus 로고    scopus 로고
    • Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses
    • USA
    • Moore KA, Nicoll RA, Schmitz D. Adenosine gates synaptic plasticity at hippocampal mossy fiber synapses. Proc Natl Acad Sci USA 2003; 100: 14397-402.
    • (2003) Proc Natl Acad Sci , vol.100 , pp. 14397-14402
    • Moore, K.A.1    Nicoll, R.A.2    Schmitz, D.3
  • 25
    • 0027935403 scopus 로고
    • Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices
    • Pak MA, Haas HL, Decking UKM, Schrader J. Inhibition of adenosine kinase increases endogenous adenosine and depresses neuronal activity in hippocampal slices. Neuropharmacology 1994; 33: 1049-53.
    • (1994) Neuropharmacology , vol.33 , pp. 1049-1053
    • Pak, M.A.1    Haas, H.L.2    Decking, U.K.M.3    Schrader, J.4
  • 26
    • 0032584389 scopus 로고    scopus 로고
    • Adenosine A1 and A2A receptor antagonists stimulate motor activity: Evidence for an increased effectiveness in aged rats
    • Popoli P, Reggio R, Pezzola A, Fuxe K, Ferre S. Adenosine A1 and A2A receptor antagonists stimulate motor activity: evidence for an increased effectiveness in aged rats. Neurosci Lett 1998; 251: 201-4.
    • (1998) Neurosci Lett , vol.251 , pp. 201-204
    • Popoli, P.1    Reggio, R.2    Pezzola, A.3    Fuxe, K.4    Ferre, S.5
  • 27
    • 0042819806 scopus 로고    scopus 로고
    • Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats
    • Rebola N, Coelho JE, Costenla AR, Lopes LV, Parada A, Oliveira CR, et al. Decrease of adenosine A1 receptor density and of adenosine neuromodulation in the hippocampus of kindled rats. Eur J Neurosci 2003; 18: 820-8.
    • (2003) Eur J Neurosci , vol.18 , pp. 820-828
    • Rebola, N.1    Coelho, J.E.2    Costenla, A.R.3    Lopes, L.V.4    Parada, A.5    Oliveira, C.R.6
  • 29
    • 0033562590 scopus 로고    scopus 로고
    • The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions
    • Svenningsson P, Nomikos GG, Fredholm BB. The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions. J Neurosci 1999; 19: 4011-22.
    • (1999) J Neurosci , vol.19 , pp. 4011-4022
    • Svenningsson, P.1    Nomikos, G.G.2    Fredholm, B.B.3
  • 30
    • 0027332570 scopus 로고
    • 6-cyclopentyl adenosine and 8-cyclopentyl-1,3- dipropylxanthine on N-methyl-D-aspartate induced seizures in mice
    • 6-cyclopentyl adenosine and 8-cyclopentyl-1,3-dipropylxanthine on N-methyl-D-aspartate induced seizures in mice. Eur J Pharmacol 1993; 249: 265-70.
    • (1993) Eur J Pharmacol , vol.249 , pp. 265-270
    • Von Lubitz, D.K.J.E.1    Paul, I.A.2    Carter, M.3    Jacobson, K.A.4
  • 32
    • 0028158694 scopus 로고
    • Status epilepticus may be caused by loss of adenosine anticonvulsant mechanisms
    • Young D, Dragunow M. Status epilepticus may be caused by loss of adenosine anticonvulsant mechanisms. Neuroscience 1994; 58: 245-61.
    • (1994) Neuroscience , vol.58 , pp. 245-261
    • Young, D.1    Dragunow, M.2
  • 33
    • 0028172348 scopus 로고
    • Endogenous adenosine deaminase does not modulate synaptic transmission in rat hippocampal slices under normoxic or hypoxic conditions
    • Zhu PJ, Krnjevic K. Endogenous adenosine deaminase does not modulate synaptic transmission in rat hippocampal slices under normoxic or hypoxic conditions. Neuroscience 1994; 63: 489-97.
    • (1994) Neuroscience , vol.63 , pp. 489-497
    • Zhu, P.J.1    Krnjevic, K.2
  • 34
    • 0037109262 scopus 로고    scopus 로고
    • The use of real-time PCR with fluorogenic probes for the rapid selection of mutant neuroectodermal grafts
    • Zumsteg V, Boison D. The use of real-time PCR with fluorogenic probes for the rapid selection of mutant neuroectodermal grafts. J Neurosci Methods 2002; 120: 85-94.
    • (2002) J Neurosci Methods , vol.120 , pp. 85-94
    • Zumsteg, V.1    Boison, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.