-
2
-
-
0001996953
-
HIV cDNA integration: Molecular biology and inhibitor development
-
C.M. Farnet, and F.D. Bushman HIV cDNA integration: molecular biology and inhibitor development AIDS 10 1996 S3 S11
-
(1996)
AIDS
, vol.10
-
-
Farnet, C.M.1
Bushman, F.D.2
-
3
-
-
0031434606
-
Molecular mechanisms in retrovirus DNA integration
-
E. Asante-Appiah, and A.M. Skalka Molecular mechanisms in retrovirus DNA integration Antiviral Res. 36 1997 139 156
-
(1997)
Antiviral Res.
, vol.36
, pp. 139-156
-
-
Asante-Appiah, E.1
Skalka, A.M.2
-
4
-
-
0346036088
-
HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells
-
P. Cherepanov, G. Maertens, P. Proost, B. Devreese, J.V. Beeumen, Y. Engelborghs, E.D. Clercq, and Z. Debyser HIV-1 integrase forms stable tetramers and associates with LEDGF/p75 protein in human cells J. Biol. Chem. 278 2003 372 381
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 372-381
-
-
Cherepanov, P.1
Maertens, G.2
Proost, P.3
Devreese, B.4
Beeumen, J.V.5
Engelborghs, Y.6
Clercq, E.D.7
Debyser, Z.8
-
5
-
-
14244264128
-
HIV-1 integrase crosslinked oligomers are active in vitro
-
A.L. Faure, C. Calmels, C. Desjobert, M. Castroviejo, A. Caumont-Sarcos, L. Tarrago-Litvak, S. Litvak, and V. Pariss HIV-1 integrase crosslinked oligomers are active in vitro Nucleic Acids Res. 33 2005 977 986
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 977-986
-
-
Faure, A.L.1
Calmels, C.2
Desjobert, C.3
Castroviejo, M.4
Caumont-Sarcos, A.5
Tarrago-Litvak, L.6
Litvak, S.7
Pariss, V.8
-
6
-
-
0037126629
-
Structure of a two domain fragment of HIV-1 integrase: Implications for domain organization in the intact protein
-
J.Y. Wang, H. Ling, W. Yang, and R. Craigie Structure of a two domain fragment of HIV-1 integrase: implications for domain organization in the intact protein EMBO J. 20 2001 7333 7343
-
(2001)
EMBO J.
, vol.20
, pp. 7333-7343
-
-
Wang, J.Y.1
Ling, H.2
Yang, W.3
Craigie, R.4
-
7
-
-
0034468560
-
Repair of gaps in retroviral DNA integration intermediates
-
K.E. Yoder, and F.D. Bushman Repair of gaps in retroviral DNA integration intermediates J. Virol. 74 2000 11192 11200
-
(2000)
J. Virol.
, vol.74
, pp. 11192-11200
-
-
Yoder, K.E.1
Bushman, F.D.2
-
8
-
-
0032510707
-
Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex
-
T.S. Heuer, and P.O. Brown Photo-cross-linking studies suggest a model for the architecture of an active human immunodeficiency virus type 1 integrase-DNA complex Biochemistry 37 1998 6667 6678
-
(1998)
Biochemistry
, vol.37
, pp. 6667-6678
-
-
Heuer, T.S.1
Brown, P.O.2
-
9
-
-
0037234457
-
Modeling HIV-1 integrase complexes based on their hydrodynamic properties
-
A.A. Podtelezhnikov, and J.A. McCammon Modeling HIV-1 integrase complexes based on their hydrodynamic properties Biopolymers 68 2003 110 120
-
(2003)
Biopolymers
, vol.68
, pp. 110-120
-
-
Podtelezhnikov, A.A.1
McCammon, J.A.2
-
11
-
-
6044232037
-
Spectroscopic studies of diketoacids-metal interactions. a probing tool for the pharmacophoric intermetallic distance in the HIV-1 integrase active site
-
C. Maurin, F. Bailly, E. Buisine, H. Vezin, G. Mbemba, J.F. Mouscadet, and P. Cotelle Spectroscopic studies of diketoacids-metal interactions. A probing tool for the pharmacophoric intermetallic distance in the HIV-1 integrase active site J. Med. Chem. 47 2004 5583 5586
-
(2004)
J. Med. Chem.
, vol.47
, pp. 5583-5586
-
-
Maurin, C.1
Bailly, F.2
Buisine, E.3
Vezin, H.4
Mbemba, G.5
Mouscadet, J.F.6
Cotelle, P.7
-
12
-
-
0030746054
-
Binding of different cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity
-
G. Bujacz, J. Alexandratos, A. Wlodawer, G. Merkel, M. Andrake, R.A. Katz, and A.M. Skalka Binding of different cations to the active site of avian sarcoma virus integrase and their effects on enzymatic activity J. Biol. Chem. 272 1997 18161 18168
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18161-18168
-
-
Bujacz, G.1
Alexandratos, J.2
Wlodawer, A.3
Merkel, G.4
Andrake, M.5
Katz, R.A.6
Skalka, A.M.7
-
13
-
-
0037469137
-
Solution structure of the RNase H domain of the HIV-1 reverse transcriptase in the presence of magnesium
-
K. Pari, and R.E. London Solution structure of the RNase H domain of the HIV-1 reverse transcriptase in the presence of magnesium Biochemistry 42 2003 639 650
-
(2003)
Biochemistry
, vol.42
, pp. 639-650
-
-
Pari, K.1
London, R.E.2
-
14
-
-
0842304431
-
Prediction of HIV-1 integrase/viral DNA interactions in the catalytic domain by fast molecular docking
-
A.A. Adesokan, and J.M. Briggs Prediction of HIV-1 integrase/viral DNA interactions in the catalytic domain by fast molecular docking J. Med. Chem. 47 2004 821 828
-
(2004)
J. Med. Chem.
, vol.47
, pp. 821-828
-
-
Adesokan, A.A.1
Briggs, J.M.2
-
15
-
-
0025908083
-
Crystal structure of the RNase H Domain of HIV-1 reverse transcriptase
-
J.F. Davies, Z. Hostomska, Z. Hostomsky, S.R. Jordan, and D.A. Matthews Crystal structure of the RNase H Domain of HIV-1 reverse transcriptase Science 252 1991 88 95
-
(1991)
Science
, vol.252
, pp. 88-95
-
-
Davies, J.F.1
Hostomska, Z.2
Hostomsky, Z.3
Jordan, S.R.4
Matthews, D.A.5
-
16
-
-
13044295993
-
Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: A platform for antiviral drug design
-
Y. Goldgur, R. Craigie, G.H. Cohen, T. Fujiwara, T. Yoshinaga, T. Fujishita, H. Sugimoto, T. Endo, H. Murai, and D.R. Davies Structure of the HIV-1 integrase catalytic domain complexed with an inhibitor: a platform for antiviral drug design Proc. Natl. Acad. Sci. USA 96 1996 13040 13043
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 13040-13043
-
-
Goldgur, Y.1
Craigie, R.2
Cohen, G.H.3
Fujiwara, T.4
Yoshinaga, T.5
Fujishita, T.6
Sugimoto, H.7
Endo, T.8
Murai, H.9
Davies, D.R.10
-
17
-
-
0032483022
-
Three new structures of the core domain of HIV-1 integrase: An active site that binds magnesium
-
Y. Goldgur, F. Dyda, A.B. Hickman, T.M. Jenkins, R. Craigie, and D.R. Davies Three new structures of the core domain of HIV-1 integrase: an active site that binds magnesium Proc. Natl. Acad. Sci. USA 95 1998 9150 9154
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 9150-9154
-
-
Goldgur, Y.1
Dyda, F.2
Hickman, A.B.3
Jenkins, T.M.4
Craigie, R.5
Davies, D.R.6
-
18
-
-
0029643858
-
The catalytic domain of avian sarcoma virus integrase: Conformation of the active-site residues in the presence of divalent cations
-
G. Bujacz, M. Jaskolski, J. Alexandratos, A. Wlodawer, G. Merkel, R.A. Katz, and A.M. Skalka The catalytic domain of avian sarcoma virus integrase: conformation of the active-site residues in the presence of divalent cations Structure 4 1996 89 96
-
(1996)
Structure
, vol.4
, pp. 89-96
-
-
Bujacz, G.1
Jaskolski, M.2
Alexandratos, J.3
Wlodawer, A.4
Merkel, G.5
Katz, R.A.6
Skalka, A.M.7
-
19
-
-
0034682511
-
Crystal structure of the HIV-1 integrase catalytic core and c-terminal domains: A model for viral DNA binding
-
J.C. Chen, J. Krucinski, L.J. Miercke, J.S. Finer-Moore, A.H. Tang, A.D. Leavitt, and R.M. Stroud Crystal structure of the HIV-1 integrase catalytic core and c-terminal domains: a model for viral DNA binding Proc. Natl. Acad. Sci. USA 97 2000 8233 8238
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 8233-8238
-
-
Chen, J.C.1
Krucinski, J.2
Miercke, L.J.3
Finer-Moore, J.S.4
Tang, A.H.5
Leavitt, A.D.6
Stroud, R.M.7
-
20
-
-
10644290389
-
-
Tripos Inc., 1699 South Hanley Rd, St. Louis, MO, USA
-
SYBYL 6.5 Manual. Tripos Inc., 1699 South Hanley Rd, St. Louis, MO, USA, 1999.
-
(1999)
SYBYL 6.5 Manual
-
-
-
21
-
-
0030986376
-
Solution structure of the N-terminal zinc binding domain of HIV-1 integrase
-
M. Cai, R. Zheng, M. Caffrey, R. Craigie, G.M. Clore, and A.M. Gronenborn Solution structure of the N-terminal zinc binding domain of HIV-1 integrase Nat. Struct. Biol. 4 1997 567 577
-
(1997)
Nat. Struct. Biol.
, vol.4
, pp. 567-577
-
-
Cai, M.1
Zheng, R.2
Caffrey, M.3
Craigie, R.4
Clore, G.M.5
Gronenborn, A.M.6
-
22
-
-
0003916606
-
-
Nijenborgh 4, 9747 AG Groningen, The Netherlands. 2001, Internet:
-
D. Van der Spoel, A.R. van Buuren, E. Apol, P.J. Meulenhoff, D.P. Tieleman, A.L.T.M. Sijbers, B. Hess, K.A. Feenstra, E. Lindahl, R. van Drunen, H.J.C. Berendsen, Gromacs User Manual version 3.0, Nijenborgh 4, 9747 AG Groningen, The Netherlands. 2001, Internet: www.gromaccs.org.
-
Gromacs User Manual Version 3.0
-
-
Van Der Spoel, D.1
Van Buuren, A.R.2
Apol, E.3
Meulenhoff, P.J.4
Tieleman, D.P.5
Sijbers, A.L.T.M.6
Hess, B.7
Feenstra, K.A.8
Lindahl, E.9
Van Drunen, R.10
Berendsen, H.J.C.11
-
23
-
-
0842322676
-
-
The Computational Center for Macromolecular Structures, San Diego Supercomputer Center: San Diego, CA
-
Y. Pommier, A.A. Pilon, K. Bajaj, A. Mazunder, N. Neamati, DOT User's Guide, version 1.0 Beta, The Computational Center for Macromolecular Structures, San Diego Supercomputer Center: San Diego, CA, 1998.
-
(1998)
DOT User's Guide, Version 1.0 Beta
-
-
Pommier, Y.1
Pilon, A.A.2
Bajaj, K.3
Mazunder, A.4
Neamati, N.5
-
24
-
-
9244260409
-
-
University of California, San Francisco
-
D.A. Case, T.A. Darden, T.E. Cheatham III, C.L. Simmerling, J. Wang, R.E. Duke, R. Luo, K.M. Merz, B. Wang, D.A. Pearlman, M. Crowley, S. Brozell, V. Tsui, H. Gohlke, J. Mongan, V. Hornak, G. Cui, P. Beroza, C. Schafmeister, J.W. Galdwell, W.S. Ross, P.A. Kollman, AMBER 8, University of California, San Francisco, 2004.
-
(2004)
AMBER 8
-
-
Case, D.A.1
Darden, T.A.2
Cheatham III, T.E.3
Simmerling, C.L.4
Wang, J.5
Duke, R.E.6
Luo, R.7
Merz, K.M.8
Wang, B.9
Pearlman, D.A.10
Crowley, M.11
Brozell, S.12
Tsui, V.13
Gohlke, H.14
Mongan, J.15
Hornak, V.16
Cui, G.17
Beroza, P.18
Schafmeister, C.19
Galdwell, J.W.20
Ross, W.S.21
Kollman, P.A.22
more..
-
25
-
-
12944270496
-
HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase
-
A.S. Espeseth, P. Felock, A. Wolfe, M. Witmer, J. Grobler, N. Anthony, M. Egbertson, J.Y. Melamed, S. Young, T. Hamill, J.L. Cole, and D.J. Hazuda HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase Proc. Natl. Acad. Sci. USA 97 2000 11244 11249
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 11244-11249
-
-
Espeseth, A.S.1
Felock, P.2
Wolfe, A.3
Witmer, M.4
Grobler, J.5
Anthony, N.6
Egbertson, M.7
Melamed, J.Y.8
Young, S.9
Hamill, T.10
Cole, J.L.11
Hazuda, D.J.12
-
26
-
-
0035964342
-
Electrostatics of nanosystems: Application to microtubules and the ribosome
-
N.A. Baker, D. Sept, S. Joseph, M.J. Holst, and J.A. McCammon Electrostatics of nanosystems: application to microtubules and the ribosome Proc. Natl. Acad. Sci. USA 98 2001 10037 10041
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 10037-10041
-
-
Baker, N.A.1
Sept, D.2
Joseph, S.3
Holst, M.J.4
McCammon, J.A.5
-
27
-
-
0029814410
-
Retroviral integrase, putting the pieces together
-
M.D. Andrake, and A.M. Skalka Retroviral integrase, putting the pieces together J. Biol. Chem. 271 1996 19633 19636
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19633-19636
-
-
Andrake, M.D.1
Skalka, A.M.2
-
28
-
-
0141927229
-
Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking
-
L.D. Luca, A. Pedretti, G. Vistoli, M.L. Barreca, L. Villa, P. Monforte, and A. Chimirri Analysis of the full-length integrase-DNA complex by a modified approach for DNA docking Biochem. Biophys. Res. Commun. 310 2003 1083 1088
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.310
, pp. 1083-1088
-
-
Luca, L.D.1
Pedretti, A.2
Vistoli, G.3
Barreca, M.L.4
Villa, L.5
Monforte, P.6
Chimirri, A.7
-
29
-
-
0026649557
-
Identification of amino acid residues critical for human immunodeficiency virus type 1 protein in vitro
-
A. Engelman, and R. Cragie Identification of amino acid residues critical for human immunodeficiency virus type 1 protein in vitro J. Virol. 66 1992 6361 6369
-
(1992)
J. Virol.
, vol.66
, pp. 6361-6369
-
-
Engelman, A.1
Cragie, R.2
-
30
-
-
0040040066
-
-
Accelrys, Inc., San Diego, CA
-
InsightII, Accelrys, Inc., San Diego, CA, http://www.accelrys.
-
InsightII
-
-
-
31
-
-
0343931519
-
Prediction of protein binding to DNA in the presence of water-mediated hydrogen bonds
-
Y.F. Deng, J. Glimm, Y. Wang, A. Korobka, M. Eisenberg, A.P. Grollman, Prediction of protein binding to DNA in the presence of water-mediated hydrogen bonds, J. Mol. Model. 5 (1999).
-
(1999)
J. Mol. Model.
, vol.5
-
-
Deng, Y.F.1
Glimm, J.2
Wang, Y.3
Korobka, A.4
Eisenberg, M.5
Grollman, A.P.6
|