Functional dissection of sequence-specific NKX2-5 DNA binding domain mutations associated with human heart septation defects using a yeast-based system

Human Molecular Genetics

Volumn 14, Issue 14, 2005, Pages 1965-1975

  Inga, Alberto ^a,c   Reamon Buettner, Stella Marie ^b   Borlak, Juergen ^b   Resnick, Michael A ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b FRAUNHOFER INSTITUTE FOR TOXICOLOGY AND EXPERIMENTAL MEDICINE   (Germany)

^c National Center Research Institute   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HOMEODOMAIN PROTEIN; TRANSCRIPTION FACTOR NKX2.5; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; CONGENITAL HEART MALFORMATION; GENE DOSAGE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HEART ATRIUM SEPTUM DEFECT; HEART DEVELOPMENT; HEART VENTRICLE SEPTUM DEFECT; HUMAN; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; SOMATIC MUTATION; TRANSACTIVATION;

BASE SEQUENCE; CLONING, MOLECULAR; DNA; HEART SEPTAL DEFECTS; HOMEODOMAIN PROTEINS; HUMANS; MUTATION; SACCHAROMYCES CEREVISIAE; TRANSCRIPTION FACTORS;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 25444528571     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddi202     Document Type: Article

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