Chiral synthesis of functionalized tetrahydropyridines: γ-aminobutyric acid uptake inhibitor analogues

Journal of Organic Chemistry

Volumn 70, Issue 20, 2005, Pages 7911-7918

  Ramachandran, P Veeraraghavan ^a   Burghardt, Thomas E ^a   Bland Berry, Layla ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; CARBOXYLATION;

ALLYLBORATION; HOMOALLYLIC AMINES; METATHESIS; TETRAHYDROPYRIDINES;

SYNTHESIS (CHEMICAL);

1 (3,3 DIPHENYLPROPYL) 2 METHYLBUT 3 ENYLAMINE; 1 (3,3 DIPHENYLPROPYL)BUT 3 ENYLAMINE; 1 CYCLOHEXYLBUT 3 EN 1 AMINE; 1 PHENYLBUT 3 EN 1 AMINE; 1 TERT BUTYL 3 ETHYL 6 PHENYL 5,6 DIHYDROPYRIDINE 1,3(2H) DICARBOXYLATE; 2 ETHOXY 1 PHENYLBUT 3 EN 1 AMINE; 2 METHYL 1 PHENYLBUT 3 EN 1 AMINE; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; ETHYL 1 METHYL 6 PHENYL 1,2,5,6 TETRAHYDROPYRIDINE 3 CARBOXYLATE; ETHYL 1,5 DIMETHYL 6 PHENYL 1,2,5,6 TETRAHYDROPYRIDINE 3 CARBOXYLATE; ETHYL 2 [(ACETYLOXY)METHYL]ACRYLATE; ETHYL 2 [[(1 CYCLOHEXYLBUT 3 ENYL]AMINO]METHYL]ACRYLATE; ETHYL 2 [[(1 PHENYLBUT 3 ENYL)AMINO]METHYL]ACRYLATE; ETHYL 2 [[(2 ETHOXY 1 PHENYLBUT 3 ENYL]AMINO]METHYL]ACRYLATE; ETHYL 2 [[(2 METHYL 1 PHENYLBUT 3 ENYL)AMINO]METHYL]ACRYLATE; ETHYL 2 [[(2 METHYL 1 PHENYLBUT 3 ENYL]AMINO]METHYL]ACRYLATE; ETHYL 2 [[1 (3,3 DIPHENYLPROPYL)BUT 3 ENYLAMINO]METHYL]ACRYLATE; ETHYL 2 [[[1 (3,3 DIPHENYLPROPYL) 2 METHYLBUT 3 ENYL]AMINO]METHYL]ACRYLATE; ETHYL 2 [[METHYL(1 PHENYLBUT 3 ENYL)AMINO]METHYL]ACRYLATE; ETHYL 6 (3,3 DIPHENYLPROPYL) 1,2,5,6 TETRAHYDROPYRIDINE 3 CARBOXYLATE; ETHYL 6 (3,3 DIPHENYLPROPYL) 5 METHYL 1,2,5,6 TETRAHYDROPYRIDINE 3 CARBOXYLATE; ETHYL 6 CYCLOHEXYL 1,2,5,6 TETRAHYDROPYRIDINE 3 CARBOXYLATE; ETHYL 6 PHENYL 1,2,5,6 TETRAHYDROPYRIDINE 3 CARBOXYLATE; FORMALDEHYDE; NITRILE; PYRIDINE DERIVATIVE; UNCLASSIFIED DRUG;

4 AMINOBUTYRIC ACID UPTAKE; ADDITION REACTION; ARTICLE; CHIRALITY; CONCENTRATION (PARAMETERS); DIASTEREOISOMER; DRUG SYNTHESIS; ELIMINATION REACTION; ENANTIOMER; RING CLOSING METATHESIS;

ALUMINUM; AMINES; CATALYSIS; GABA ANTAGONISTS; MAGNETIC RESONANCE SPECTROSCOPY; PYRIDINES; VINYL COMPOUNDS;

EID: 25444511851     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0508200     Document Type: Article

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