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Volumn 520, Issue 1-3, 2005, Pages 12-21

Blockade of 5-HT3 receptor with MDL72222 and Y25130 reduces β-amyloid protein (25-35)-induced neurotoxicity in cultured rat cortical neurons

Author keywords

Amyloid protein; 5 HT3 receptor; 5 HT3 receptor antagonist; Cortical neuron; MDL72222; Neuroprotection; Neurotoxicity; Y25130

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; AMYLOID BETA PROTEIN[25-35]; AZASETRON; BEMESETRON; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM CHANNEL L TYPE; CALCIUM ION; CASPASE 3; DIZOCILPINE; GLUTAMIC ACID; HOE 33342; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE SYNTHASE INHIBITOR; PHENYLBIGUANIDE; REACTIVE OXYGEN METABOLITE; SEROTONIN 3 ANTAGONIST; SEROTONIN 3 RECEPTOR; TETRAZOLE DERIVATIVE; VERAPAMIL;

EID: 25444475566     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2005.07.021     Document Type: Article
Times cited : (31)

References (48)
  • 2
    • 0024158068 scopus 로고
    • What is the nature of the role of the seretonergic nervous system in learning and memory: Prospects for development of an effective treatment strategy for senile dementia
    • H.J. Altman, and H.J. Normile What is the nature of the role of the seretonergic nervous system in learning and memory: prospects for development of an effective treatment strategy for senile dementia Neurobiol. Aging 9 1988 627 638
    • (1988) Neurobiol. Aging , vol.9 , pp. 627-638
    • Altman, H.J.1    Normile, H.J.2
  • 3
    • 0028980467 scopus 로고
    • β-Amyloid peptide fragment 25-35 potentiates the calcium-dependent release of excitatory amino acids from depolarized hippocampal slices
    • C. Arias, I. Arrieta, and R. Tapia β-Amyloid peptide fragment 25-35 potentiates the calcium-dependent release of excitatory amino acids from depolarized hippocampal slices J. Neurosci. Res. 41 1995 561 566
    • (1995) J. Neurosci. Res. , vol.41 , pp. 561-566
    • Arias, C.1    Arrieta, I.2    Tapia, R.3
  • 4
    • 0028989049 scopus 로고
    • 3 receptor modulation of excitatory amino acid release in the rat nucleus tractus solitarius
    • 3 receptor modulation of excitatory amino acid release in the rat nucleus tractus solitarius Neurosci. Lett. 191 1995 75 78
    • (1995) Neurosci. Lett. , vol.191 , pp. 75-78
    • Ashworth-Preece, M.A.1    Jarrott, B.2    Lawrence, A.J.3
  • 7
    • 0028233494 scopus 로고
    • Hydrogen peroxide mediates amyloid beta protein toxicity
    • C. Behl, J.B. Davis, R. Lesley, and D. Schubert Hydrogen peroxide mediates amyloid beta protein toxicity Cell 77 1994 817 827
    • (1994) Cell , vol.77 , pp. 817-827
    • Behl, C.1    Davis, J.B.2    Lesley, R.3    Schubert, D.4
  • 8
    • 0027270211 scopus 로고
    • Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2- yl)-2,5-diphenyltetrazolium bromide (MTT): Subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction
    • M.V. Berridge, and A.S. Tan Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction Arch. Biochem. Biophys. 303 1993 474 482
    • (1993) Arch. Biochem. Biophys. , vol.303 , pp. 474-482
    • Berridge, M.V.1    Tan, A.S.2
  • 9
    • 0037192392 scopus 로고    scopus 로고
    • Induction of cytochrome c-mediated apoptosis by amyloid β 25-35 requires functional mitochondria
    • S.M. Cardoso, R.H. Swerdlow, and C.R. Oliveira Induction of cytochrome c-mediated apoptosis by amyloid β 25-35 requires functional mitochondria Brain Res. 931 2002 117 125
    • (2002) Brain Res. , vol.931 , pp. 117-125
    • Cardoso, S.M.1    Swerdlow, R.H.2    Oliveira, C.R.3
  • 12
    • 0029923901 scopus 로고
    • Neuropathology of synthetic β-amyloid peptide analogs in vivo
    • S.-Y. Chen, J.W. Harding, and C.D. Barnes Neuropathology of synthetic β-amyloid peptide analogs in vivo Brain Res. 715 1994 44 50
    • (1994) Brain Res. , vol.715 , pp. 44-50
    • Chen, S.-Y.1    Harding, J.W.2    Barnes, C.D.3
  • 13
    • 0006286505 scopus 로고
    • 3 receptor antagonists in the treatment of cognitive disorders
    • F.D. Kin B.J. Jones G.J. Sanger CRC Press
    • 3 receptor antagonists in the treatment of cognitive disorders F.D. Kin B.J. Jones G.J. Sanger 5-Hydroxytryptamine-3 receptor antagonists 1994 CRC Press 203 209
    • (1994) 5-Hydroxytryptamine-3 Receptor Antagonists , pp. 203-209
    • Costal, B.1    Naylor, R.J.2
  • 14
    • 0026713423 scopus 로고
    • Beta-amyloid neurotoxicity: A discussion of in vitro findings
    • C.W. Cotman, C.J. Pike, and A. Copani Beta-amyloid neurotoxicity: a discussion of in vitro findings Neurobiol. Aging 13 1992 587 590
    • (1992) Neurobiol. Aging , vol.13 , pp. 587-590
    • Cotman, C.W.1    Pike, C.J.2    Copani, A.3
  • 16
    • 0033569760 scopus 로고    scopus 로고
    • Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates β-amyloid-induced neurodegeneration
    • F.J. Ekinci, K.U. Malik, and T.B. Shea Activation of the L voltage-sensitive calcium channel by mitogen-activated protein (MAP) kinase following exposure of neuronal cells to beta-amyloid. MAP kinase mediates β-amyloid-induced neurodegeneration J. Biol. Chem. 274 1999 30322 30327
    • (1999) J. Biol. Chem. , vol.274 , pp. 30322-30327
    • Ekinci, F.J.1    Malik, K.U.2    Shea, T.B.3
  • 17
    • 0034728670 scopus 로고    scopus 로고
    • β-Amyloid-induced calcium influx induces apoptosis in culture by oxidative stress rather than tau phosphorylation
    • F.J. Ekinci, M.D. Linsley, and T.B. Shea β-Amyloid-induced calcium influx induces apoptosis in culture by oxidative stress rather than tau phosphorylation Mol. Brain Res. 76 2000 389 395
    • (2000) Mol. Brain Res. , vol.76 , pp. 389-395
    • Ekinci, F.J.1    Linsley, M.D.2    Shea, T.B.3
  • 18
    • 0023115468 scopus 로고
    • Amino acid neurotransmitters in postmortem human brain analyzed by high performance liquid chromatography with electrochemical detection
    • D.W. Ellison, M.F. Beal, and J.B. Martin Amino acid neurotransmitters in postmortem human brain analyzed by high performance liquid chromatography with electrochemical detection J. Neurosci. Methods 19 1987 305 315
    • (1987) J. Neurosci. Methods , vol.19 , pp. 305-315
    • Ellison, D.W.1    Beal, M.F.2    Martin, J.B.3
  • 19
    • 1842471972 scopus 로고    scopus 로고
    • 25-35 inhibits glutamate uptake in cultured neurons and astrocytes: Modulation of uptake as a survival mechanism
    • 25-35 inhibits glutamate uptake in cultured neurons and astrocytes: modulation of uptake as a survival mechanism Neurobiol. Dis. 15 2004 580 589
    • (2004) Neurobiol. Dis. , vol.15 , pp. 580-589
    • Fernández-Tomé, P.1    Brera, B.2    Arévalo, M.A.3    Ceballos, M.L.4
  • 20
    • 0027320359 scopus 로고
    • β-Amyloid neurotoxicity
    • G. Forloni β-Amyloid neurotoxicity Funct. Neurology 8 1993 211 225
    • (1993) Funct. Neurology , vol.8 , pp. 211-225
    • Forloni, G.1
  • 21
    • 0028169905 scopus 로고
    • Secreted forms of β-amyloid precursor protein protect hippocampal neurons against amyloid β-peptide-induced oxidative injury
    • Y. Goodman, and M.P. Mattson Secreted forms of β-amyloid precursor protein protect hippocampal neurons against amyloid β-peptide-induced oxidative injury Exp. Neurol. 128 1994 1 12
    • (1994) Exp. Neurol. , vol.128 , pp. 1-12
    • Goodman, Y.1    Mattson, M.P.2
  • 23
    • 0029102993 scopus 로고
    • Neurodegeneration mediated by glutamate and beta-amyloid peptide: A comparison and possible interaction
    • C.W. Gray, and A.J. Patel Neurodegeneration mediated by glutamate and beta-amyloid peptide: a comparison and possible interaction Brain Res. 691 1995 169 179
    • (1995) Brain Res. , vol.691 , pp. 169-179
    • Gray, C.W.1    Patel, A.J.2
  • 24
    • 0032876784 scopus 로고    scopus 로고
    • Activation of caspase-3 in β-amyloid-induced apoptosis of cultured rat cortical neurons
    • J. Harada, and M. Sugimoto Activation of caspase-3 in β-amyloid-induced apoptosis of cultured rat cortical neurons Brain Res. 842 1999 311 323
    • (1999) Brain Res. , vol.842 , pp. 311-323
    • Harada, J.1    Sugimoto, M.2
  • 26
    • 0028984950 scopus 로고
    • 3 receptor antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the forebrain cholinergic system
    • 3 receptor antagonists WAY-100579 and ondansetron on spatial learning in the water maze in rats with excitotoxic lesions of the forebrain cholinergic system Psychopharmacology (Berlin) 117 1995 318 332
    • (1995) Psychopharmacology (Berlin) , vol.117 , pp. 318-332
    • Hodges, H.1    Fletcher, A.2
  • 27
    • 0032937187 scopus 로고    scopus 로고
    • Disturbances of calcium homeostasis in ischemic stroke: Therapeutical implication
    • J. Horn, P.J.A.M. Brouwers, and M. Limburg Disturbances of calcium homeostasis in ischemic stroke: therapeutical implication CNS Drugs 11 1999 373 386
    • (1999) CNS Drugs , vol.11 , pp. 373-386
    • Horn, J.1    Brouwers, P.J.A.M.2    Limburg, M.3
  • 28
    • 0023121855 scopus 로고
    • Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve
    • S.J. Ireland, and M.B. Tyers Pharmacological characterization of 5-hydroxytryptamine-induced depolarization of the rat isolated vagus nerve Brit. J. Pharmacol. 90 1987 229 238
    • (1987) Brit. J. Pharmacol. , vol.90 , pp. 229-238
    • Ireland, S.J.1    Tyers, M.B.2
  • 29
    • 0033119182 scopus 로고    scopus 로고
    • Generation of reactive oxygen species, release of L-glutamate and activation of caspases are required for oxygen-induced apoptosis of embryonic hippocampal neurons in culture
    • Y. Ishikawa, T. Satoh, Y. Enokido, C. Nishio, T. Ikeuchi, and H. Hatanaka Generation of reactive oxygen species, release of L-glutamate and activation of caspases are required for oxygen-induced apoptosis of embryonic hippocampal neurons in culture Brain Res. 824 1999 71 80
    • (1999) Brain Res. , vol.824 , pp. 71-80
    • Ishikawa, Y.1    Satoh, T.2    Enokido, Y.3    Nishio, C.4    Ikeuchi, T.5    Hatanaka, H.6
  • 31
    • 0033593456 scopus 로고    scopus 로고
    • Multiple pathways of apoptosis in PC12 cells. CrmA inhibits apoptosis induced by beta-amyloid
    • K.J. Ivins, J.K. Ivins, J.P. Sharp, and C.W. Cotman Multiple pathways of apoptosis in PC12 cells. CrmA inhibits apoptosis induced by beta-amyloid J. Biol. Chem. 274 1999 2107 2112
    • (1999) J. Biol. Chem. , vol.274 , pp. 2107-2112
    • Ivins, K.J.1    Ivins, J.K.2    Sharp, J.P.3    Cotman, C.W.4
  • 32
    • 0026574860 scopus 로고
    • 3 receptor antagonist on ischemia-induced decrease in CA1 field potential in rat hippocampal slices
    • 3 receptor antagonist on ischemia-induced decrease in CA1 field potential in rat hippocampal slices Eur. J. Pharmacol. 224 1992 51 56
    • (1992) Eur. J. Pharmacol. , vol.224 , pp. 51-56
    • Kagami-Ishi, Y.1    Shibata, S.2    Watanabe, S.3
  • 34
    • 0025110182 scopus 로고
    • β-Amyloid protein increases the vulnerability of cultured neurons to excitotoxic damage
    • J.Y. Koh, L.L. Yang, and C.W. Cotman β-Amyloid protein increases the vulnerability of cultured neurons to excitotoxic damage Brain Res. 533 1990 315 320
    • (1990) Brain Res. , vol.533 , pp. 315-320
    • Koh, J.Y.1    Yang, L.L.2    Cotman, C.W.3
  • 39
    • 0030814675 scopus 로고    scopus 로고
    • Thornberry NA. Caspases: Killer proteases
    • D.W. Nicholson Thornberry NA. Caspases: killer proteases Trends Biochem. Sci. 22 1997 299 306
    • (1997) Trends Biochem. Sci. , vol.22 , pp. 299-306
    • Nicholson, D.W.1
  • 40
    • 0027496238 scopus 로고
    • A radical hypothesis for neurodegeneration
    • C.W. Olanow A radical hypothesis for neurodegeneration Trends Neurosci. 16 1993 439 444
    • (1993) Trends Neurosci. , vol.16 , pp. 439-444
    • Olanow, C.W.1
  • 42
    • 0020681411 scopus 로고
    • Effect of specific serotonergic leions on cholinergic neurons in the hippocampus, cortex and striatum
    • S.E. Robinson Effect of specific serotonergic leions on cholinergic neurons in the hippocampus, cortex and striatum Life Sci. 32 1983 345 353
    • (1983) Life Sci. , vol.32 , pp. 345-353
    • Robinson, S.E.1
  • 44
    • 0035917831 scopus 로고    scopus 로고
    • Activated caspase-3 expression in Alzheimer's and aged control brain: Correlation with Alzheimer pathology
    • J.H. Su, M. Zhao, A.J. Anderson, A. Srinivasan, and C.W. Cotman Activated caspase-3 expression in Alzheimer's and aged control brain: correlation with Alzheimer pathology Brain Res. 898 2001 350 357
    • (2001) Brain Res. , vol.898 , pp. 350-357
    • Su, J.H.1    Zhao, M.2    Anderson, A.J.3    Srinivasan, A.4    Cotman, C.W.5
  • 45
    • 0028331604 scopus 로고
    • Amyloid β protein-induced neuronal cell death: Neurotoxic properties of aggregated amyloid β protein
    • K. Ueda, Y. Fukui, and H. Kageyama Amyloid β protein-induced neuronal cell death: neurotoxic properties of aggregated amyloid β protein Brain Res. 639 1994 240 244
    • (1994) Brain Res. , vol.639 , pp. 240-244
    • Ueda, K.1    Fukui, Y.2    Kageyama, H.3
  • 47
    • 0024472686 scopus 로고
    • 3 receptors in the human brain: Autoradiographic visualization using 3[H]ICS 205-930
    • 3 receptors in the human brain: autoradiographic visualization using 3[H]ICS 205-930 Neuroscience 31 1989 393 400
    • (1989) Neuroscience , vol.31 , pp. 393-400
    • Waeber, C.1    Hoyer, D.2    Palacios, J.M.3
  • 48
    • 0033036691 scopus 로고    scopus 로고
    • β-Amyloid peptide fragment 31-35 induces apoptosis in cultured cortical neurons
    • X.T. Yan, J.T. Qiao, Y. Dou, and Z.D. Qiao β-Amyloid peptide fragment 31-35 induces apoptosis in cultured cortical neurons Neuroscience 92 1999 177 184
    • (1999) Neuroscience , vol.92 , pp. 177-184
    • Yan, X.T.1    Qiao, J.T.2    Dou, Y.3    Qiao, Z.D.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.