Inhibitors of polyamine biosynthesis decrease the expression of the metalloproteases meprin α and MMP-7 in hormone-independent human breast cancer cells

Clinical and Experimental Metastasis

Volumn 22, Issue 4, 2005, Pages 331-339

  Matters, Gail L ^a   Manni, Andrea ^a   Bond, Judith S ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Breast cancer invasion; DFMO; Metalloproteases; Polyamines; SAM486A

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACTINONIN; ADENOSYLMETHIONINE DECARBOXYLASE; DECARBOXYLASE INHIBITOR; EFLORNITHINE; GELATINASE A; HORMONE; INTERSTITIAL COLLAGENASE; MATRILYSIN; MATRIX METALLOPROTEINASE 14; MEPRIN; MESSENGER RNA; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; POLYAMINE; PUTRESCINE; SAM 486 A; STROMELYSIN; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CANCER INVASION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; METASTASIS; POLYAMINE SYNTHESIS; PROTEIN CONTENT; PROTEIN EXPRESSION; REGULATORY MECHANISM; RNA ANALYSIS; SIGNAL TRANSDUCTION;

AMIDINES; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; DOWN-REGULATION; EFLORNITHINE; ENZYME INHIBITORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLAVONOIDS; GENE EXPRESSION; HUMANS; HYDROXAMIC ACIDS; INDANS; MATRIX METALLOPROTEINASE 7; METALLOENDOPEPTIDASES; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NEOPLASM INVASIVENESS; ORNITHINE DECARBOXYLASE; PHOSPHORYLATION; POLYAMINES; RNA, MESSENGER;

EID: 25444454560     PISSN: 02620898     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10585-005-0660-5     Document Type: Article

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