Physical exercise capacity is associated with coronary and peripheral vascular function in healthy young adults

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 289, Issue 4 58-4, 2005, Pages

  Hägg, Ulrika ^a   Wandt, Birger ^b   Bergström, Göran ^b   Volkmann, Reinhard ^b   Gan, Li Ming ^a,b,c  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Coronary flow velocity reserve; Doppler echocardiography; Endothelial function; Intimamedia thickness; Stiffness

Indexed keywords

ADULT; ARTERY INTIMA THICKNESS; ARTERY MEDIA; ARTERY MEDIA THICKNESS; ARTICLE; BLOOD FLOW VELOCITY; BLOOD VESSEL COMPLIANCE; BLOOD VESSEL FUNCTION; CARDIOVASCULAR FUNCTION; CARDIOVASCULAR HEALTH; COMMON CAROTID ARTERY; CORONARY ARTERY BLOOD FLOW; CORONARY BLOOD VESSEL; CORONARY FLOW VELOCITY RESERVE; DOPPLER ECHOCARDIOGRAPHY; ENDOTHELIUM FUNCTION; EXERCISE; FEMALE; FLOW MEDIATED VASODILATION; FOREARM BLOOD FLOW; HEART PROTECTION; HUMAN; INTIMA; LEFT ANTERIOR DESCENDING CORONARY ARTERY; LIFESTYLE; MALE; MAXIMUM OXYGEN UPTAKE CAPACITY; MEASUREMENT; NORMAL HUMAN; OXYGEN CONSUMPTION; PERIPHERAL CIRCULATION; PHYSICAL ACTIVITY; PRIORITY JOURNAL; STIFFNESS INDEX; THICKNESS; VASCULAR ENDOTHELIUM; VASODILATATION;

ADULT; CAROTID ARTERY, COMMON; CORONARY CIRCULATION; ECHOCARDIOGRAPHY, DOPPLER; ENDOTHELIUM, VASCULAR; EXERCISE; FEMALE; FOREARM; HUMANS; LIFE STYLE; MALE; REGIONAL BLOOD FLOW; VASODILATION;

EID: 25444453445     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00135.2005     Document Type: Article

References (43)

1. Albertal M, Voskuil M, Piek JJ, de Bruyne B, Van Langenhove G, Kay PI, Costa MA, Boersma E, Beijsterveldt T, Sousa JE, Belardi JA, and Serruys PW, on behalf of Doppler Endpoints Balloon Angioplasty Trial Europe (DEBATE) II Study Group. Coronary flow velocity reserve after percutaneous interventions is predictive of periprocedural outcome. Circulation 105: 1573-1578, 2002.
2. Åstrand I. Aerobic work capacity in men and women with special reference to age. Acta Physiol Scand 49, Suppl 169: 1-92, 1960.
3. Blair SN, Kohl HW III, Paffenbarger RS Jr, Clark DG, Cooper KH, and Gibbons LW. Physical fitness and all-cause mortality. A prospective study of healthy men and women. JAMA 262: 2395-2401, 1989.
4. Blake GJ, Rifai N, Buring JE, and Ridker PM. Blood pressure, C-reactive protein, and risk of future cardiovascular events. Circulation 108: 2993-2999, 2003.
5. Brendle DC, Joseph LJO, Corretti MC, Gardner AW, and Katzel LI. Effects of exercise rehabilitation on endothelial reactivity in older patients with peripheral arterial disease. Am J Cardiol 87: 324-329, 2001.
6. Bruel A, Ortoft G, and Oxlund H. Inhibition of cross-links in collagen is associated with reduced stiffness of the aorta in young rats. Atherosclerosis 140: 135-145, 1998.
7. Burelle Y, Wambolt RB, Grist M, Parsons HL, Chow JCF, Antler C, Bonen A, Keller A, Dunaway GA, Popov KM, Hochachka PW, and Allard MF. Regular exercise is associated with a protective metabolic phenotype in the rat heart. Am J Physiol Heart Circ Physiol 287: H1055-H1063, 2004.
8. Buus NH, Bottcher M, Hermansen F, Sander M, Nielsen TT, and Mulvany MJ. Influence of nitric oxide synthase and adrenergic inhibition on adenosine-induced myocardial hyperemia. Circulation 104: 2305-2310, 2001.
9. Clarkson P, Montgomery HE, Mullen MJ, Donald AE, Powe AJ, Bull T, Jubb M, World M, and Deanfield JE. Exercise training enhances endothelial function in young men. J Am Coll Cardiol 33: 1379-1385, 1999.
10. Corretti MC, Anderson TJ, Benjamin EJ, Celermajer D, Charbonneau F, Creager MA, Deanfield J, Drexler H, Gerhard-Herman M, and Herrington D. Guidelines for the ultrasound assessment of endothelial-dependent flow-mediated vasodilation of the brachial artery: a report of the International Brachial Artery Reactivity Task Force. J Am Coll Cardiol 39: 257-265, 2002.
11. Davies KJ, Quintanilha AT, Brooks GA, and Packer L. Free radicals and tissue damage produced by exercise. Biochem Biophys Res Commun 107: 1198-1205, 1982.
12. Duffy SJ, Castle SF, Harper RW, and Meredith IT. Contribution of vasodilator prostanoids and nitric oxide to resting flow, metabolic vasodilation, and flow-mediated dilation in human coronary circulation. Circulation 100: 1951-1957, 1999.
13. Galetta F, Franzoni F, Femia FR, Bartolomucci F, Carpi A, and Santoro G. Left ventricular diastolic function and carotid artery wall in elderly athletes and sedentary controls. Biomed Pharmacother 58: 437-442, 2004.
14. Goto C, Higashi Y, Kimura M, Noma K, Hara K, Nakagawa K, Kawamura M, Chayama K, Yoshizumi M, and Nara I. Effect of different intensities of exercise on endothelium-dependent vasodilation in humans: role of endothelium-dependent nitric oxide and oxidative stress. Circulation 108: 530-535, 2003.
15. Green DJ, Maiorana A, O'Driscoll G, and Taylor R. Effect of exercise training on endothelium-derived nitric oxide function in humans. J Physiol 561: 1-25, 2004.
16. Hägg U, Andersson I, Naylor AS, Grönros J, Jonsdottir IH, Bergström G, and Gan LM. Voluntary physical exercise-induced vascular effects in spontaneously hypertensive rats. Clin Sci (Lond) 107: 571-581, 2004.
17. Hambrecht R, Walther C, Mobius-Winkler S, Gielen S, Linke A, Conradi K, Erbs S, Kluge R, Kendziorra K, Sabri O, Sick P, and Schuler G. Percutaneous coronary angioplasty compared with exercise training in patients with stable coronary artery disease: a randomized trial. Circulation 109: 1371-1378, 2004.
18. Hambrecht R, Wolf A, Gielen S, Linke A, Hofer J, Erbs S, Schoene N, and Schuler G. Effect of exercise on coronary endothelial function in patients with coronary artery disease. N Engl J Med 342: 454-460, 2000.
19. Hildick-Smith DJ, Johnson PJ, Wisbey CR, Winter EM, and Shapiro LM. Coronary flow reserve is supranormal in endurance athletes: an adenosine transthoracic echocardiographic study. Heart 84: 383-389, 2000.
20. Hirata K, Amudha K, Elina R, Hozumi T, Yoshikawa J, Homma S, and Lang CC. Measurement of coronary vasomotor function: getting to the heart of the matter in cardiovascular research. Clin Sci (Lond) 107: 449-460, 2004.
21. Hornig B, Maier V, and Drexler H. Physical training improves endothelial function in patients with chronic heart failure. Circulation 93: 210-214, 1996.
22. Hozumi T, Yoshida K, Akasaka T, Asami Y, Ogata Y, Takagi T, Kaji S, Kawamoto T, Ueda Y, and Morioka S. Noninvasive assessment of coronary flow velocity and coronary flow velocity reserve in the left anterior descending coronary artery by Doppler echocardiography: comparison with invasive technique. J Am Coll Cardiol 32: 1251-1259, 1998.
23. Hozumi T, Yoshida K, Ogata Y, Akasaka T, Asami Y, Takagi T, and Morioka S. Noninvasive assessment of significant left anterior descending coronary artery stenosis by coronary flow velocity reserve with transthoracic color Doppler echocardiography. Circulation 97: 1557-1562, 1998.
24. Kawasaki T, Sasayama S, Yagi S, Asakawa T, and Hirai T. Non-invasive assessment of the age related changes in stiffness of major branches of the human arteries. Cardiovasc Res 21: 678-687, 1987.
25. Kingwell BA, Cameron JD, Gillies KJ, Jennings GL, and Dart AM. Arterial compliance may influence baroreflex function in athletes and hypertensives. Am J Physiol Heart Circ Physiol 268: H411-H418, 1995.
26. Lanne T, Hansen F, Mangell P, and Sonesson B. Differences in mechanical properties of the common carotid artery and abdominal aorta in healthy males. J Vasc Surg 20: 218-225, 1994.
27. Lind L, Sarabi M, and Millgard J. Methodological aspects of the evaluation of endothelium-dependent vasodilatation in the human forearm. Clin Physiol 18: 81-87, 1998.
28. Liuba P, Persson J, Luoma J, Yla-Herttuala S, and Pesonen E. Acute infections in children are accompanied by oxidative modification of LDL and decrease of HDL cholesterol, and are followed by thickening of carotid intima-media. Eur Heart J 24: 515-521, 2003.
29. Mishra RK, Dorbala S, Logsetty G, Hassan A, Heinonen T, Schelbert HR, and Di Carli MF. Quantitative relation between hemodynamic changes during intravenous adenosine infusion and the magnitude of coronary hyperemia: implications for myocardial perfusion imaging. J Am Coll Cardiol 45: 553, 2005.
30. Miyachi M, Kawano H, Sugawara J, Takahashi K, Hayashi K, Yamazaki K, Tabata I, and Tanaka H. Unfavorable effects of resistance training on central arterial compliance: a randomized intervention study. Circulation 110: 2858-2863, 2004.
31. Mulvany MJ. Small artery remodeling and significance in the development of hypertension. News Physiol Sci 17: 105-109, 2002.
32. Otsuka R, Watanabe H, Hirata K, Tokai K, Muro T, Yoshiyama M, Takeuchi K, and Yoshikawa J. Acute effects of passive smoking on the coronary circulation in healthy young adults. JAMA 286: 436-441, 2001.
33. Paffenbarger RS Jr, Hyde RT, Wing AL, Lee IM, Jung DL, and Kampert JB. The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. N Engl J Med 328: 538-545, 1993.
34. Quinones MA, Otto CM, Stoddard M, Waggoner A, and Zoghbi WA. Recommendations for quantification of Doppler echocardiography: a report from the Doppler Quantification Task Force of the Nomenclature and Standards Committee of the American Society of Echocardiography. J Am Soc Echocardiogr 15: 167-184, 2002.
35. Rauramaa R, Rankinen T, Tuomainen P, Vaisanen S, and Mercuri M. Inverse relationship between cardiorespiratory fitness and carotid atherosclerosis. Atherosclerosis 112: 213-221, 1995.
36. Saraste M, Koskenvuo JW, Knuuti J, Toikka JO, Laine H, Niemi P, Sakuma H, and Hartiala JJ. Coronary flow reserve: measurement with transthoracic Doppler echocardiography is reproducible and comparable with positron emission tomography. Clin Physiol 21: 114-122, 2001.
37. Tanaka H, Dinenno FA, Monahan KD, Clevenger CM, DeSouza CA, and Seals DR. Aging, habitual exercise, and dynamic arterial compliance. Circulation 102: 1270-1275, 2000.
38. Tanaka H, Seals DR, Monahan KD, Clevenger CM, DeSouza CA, and Dinenno FA. Regular aerobic exercise and the age-related increase in carotid artery intima-media thickness in healthy men. J Appl Physiol 92: 1458-1464, 2002.
39. Tronc F, Wassef M, Esposito B, Henrion D, Glagov S, and Tedgui A. Role of NO in flow-induced remodeling of the rabbit common carotid artery. Arterioscler Thromb Vasc Biol 16: 1256-1262, 1996.
40. Walldius G, Jungner I, Holme I, Aastveit AH, Kolar W, and Steiner E. High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study. Lancet 358: 2026-2033, 2001.
41. Wendelhag I, Gustavsson T, Suurkula M, Berglund G, and Wikstrand J. Ultrasound measurement of wall thickness in the carotid artery: fundamental principles and description of a computerized analysing system. Clin Physiol 11: 565-577, 1991.
42. Windecker S, Allemann Y, Billinger M, Pohl T, Hutter D, Orsucci T, Blaga L, Meier B, and Seiler C. Effect of endurance training on coronary artery size and function in healthy men: an invasive followup study. Am J Physiol Heart Circ Physiol 282: H2216-H2223, 2002.
43. Vita JA, Treasure CB, Nabel EG, McLenachan JM, Fish RD, Yeung AC, Vekshtein VI, Selwyn AP, and Ganz P. Coronary vasomotor response to acetylcholine relates to risk factors for coronary artery disease. Circulation 81: 491-497, 1990.