Bone morphogenetic proteins in the skeletal system;Bone morphogenetic proteins im skelettsystem - Eine zusammenfassende darstellung

Zeitschrift fur Rheumatologie

Volumn 64, Issue 6, 2005, Pages 416-422

  Bramlage, C P ^a   Haupl T ^b   Kaps, C ^b   Bramlage, P ^c   Muller G A ^a   Strutz, F ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^c DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

Author keywords

BMP; Bone morphogenetic protein; Cartilage and bone regeneration

Indexed keywords

BONE MORPHOGENETIC PROTEIN; BONE MORPHOGENETIC PROTEIN 2; BONE MORPHOGENETIC PROTEIN 4; BONE MORPHOGENETIC PROTEIN 5; BONE MORPHOGENETIC PROTEIN 6; BONE MORPHOGENETIC PROTEIN RECEPTOR; OSTEOGENIC PROTEIN 1; PROCOLLAGEN C PROTEINASE; TRANSFORMING GROWTH FACTOR BETA;

ABORTION; ARTHRITIS; ARTHROPATHY; CARTILAGE; CLASSIFICATION; FETUS DEVELOPMENT; FRACTURE; FRACTURE HEALING; GENE MUTATION; NONHUMAN; ORGANOGENESIS; OSTEOARTHRITIS; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; SKELETON; TISSUE REGENERATION; TISSUE REPAIR;

ANIMALS; BONE AND BONES; BONE DISEASES; BONE MORPHOGENETIC PROTEINS; BONE REGENERATION; FRACTURE HEALING; FRACTURES, BONE; HUMANS; MODELS, BIOLOGICAL;

EID: 25444449011     PISSN: 03401855     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00393-005-0665-0     Document Type: Review

References (30)

1. Azari K, Doll BA et al (2001) Therapeutic potential of bone morphogenetic proteins. Expert Opin Investig Drugs 10(9):p 1677-1686
2. Bramlage C (2003) Expression morphogener Wachstumsfaktoren im physiologischen Gelenk und ihre Regulation in akuten und chronischen Gelenkerkrankungen, Promotion. Medizinische Klinik mit Schwerpunkt Rheumatologie, Charite, Berlin.
3. Chubinskaya SKB, Merrihew C, Heretis K, Rueger DC, Kuettner KE (2002) Age-related changes in cartilage endogenous OP-1: New ELISA method. Biochimica et Biophysica Acta-Molecular Basis of Disease 1588(2):126-134
4. Chubinskaya S, Kuettner KE (2003) Regulation of osteogenic proteins by chondrocytes. Int J Biochem Cell Biol 35(9):p 1323-1340
5. Derynck R, Feng XH (1997) TGF-beta receptor signaling. Biochim Biophys Acta 1333(2):p F105-150
6. Ducy P, Karsenty G (2000) The family of bone morphogenetic proteins. Kidney Int 57(6):p 2207-2214
7. Edwards CJ, Francis-West PH (2001) Bone morphogenetic proteins in the development and healing of synovial joints. Semin Arthritis Rheum 31(1): 33-42
8. Erlacher LUF, Luyten F, Smolen J, Graininger W (1999) Zellbiologie des Chondrozyten im Hinblick auf die Arthroseentstehung: Rolle der Knorpelspezifischen Wachstumsfaktoren. J Miner Stoffwechs 2(1):6-10
9. Francis-West PHP J, Lee K, Archer CW (1999) BMP/GDF-signalling interactions during synovial joint development. Cell Tissue Res 296:111-119
10. Frenkel SRSP, Mehrara BJ, Chin GS, Steinbrech DS, Brent B, Gittes GK, Longaker MT (2000) Transforming-Growth-Factor beta superfamily members: role in cartilage modeling. Plast Reconstr Surg 105(3):p 980-990
11. Giltaij L (2002) BMP-7 in Orthopedic Applications: A Review. Journal of Musculoskeletal Research 6(1):55-62
12. Janitz MHV, Bottcher U, Landt O, Lauster R (1998) Three alternatively spliced variants of the gene coding for the human bone morphogenetic protein-1. J Mol Med 76(2):141-146
13. Kaps C, Bramlage C, Smolian H, Haisch A, Ungethüm U, Burmester GR, Sittinger M, Gross G, Häupl T (2002) Bone morphogenetic proteins promote cartilage differentiation and protect engineered artificial cartilage from fibroblast invasion and destruction. Arthritis Rheum 46(1):149-162
14. Kawabata M, Imamura T, Miyazono K (1998) Signal transduction by bone morphogenetic proteins. Cytokine Growth Factor Rev 9(1):49-61
15. Kessler E, Takahara K et al (1996) Bone morphogenetic protein-1: the type I procollagen C-proteinase. Science. 271(5247):360-362
16. King JAMP, Seung KJ, Kingsley DM (1994) BMP5 and the molecular, skeletal, and soft-tissue alterations in short ear mice. Dev Biol 166:112-122
17. Kingsley DM (1994) The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms. Genes Dev 8(2):p 133-146
18. Massague J (1992) Receptors for the TGF-beta family. Cell 69(7):1067-1070
19. Massague J (2000) How cells read TGF-beta signals. Nat Rev Mol Cell Biol 1(3):p 169-178
20. Massague JCY-G (2000) Controlling TGF-beta signaling. Genes Dev 14: 627-644
21. Nishida YKC, Eger W, Kuettner KE, Knudson W (2000) Osteogenic protein-1 stimulates cell-associated matrix assembly by normal human articular chondrocytes: upregulation of hyaluronan synthase. Arthritis Rheum 43:206-214
22. Sakou T (1998) Bone morphogenetic proteins: from basic studies to clinical approaches. Bone 22(6):p 591-603
23. Schmitt JMHK, Winn SR, Hollinger JO (1999) Bone-Morphogenetic-Proteins: an update on basic biology and clinical relevance. J Orthop Res 17(2): 269-278
24. Sellers RPD, Morris E (1997) The effect of recombinant human bone morphogenetic protein-2 (rhBMP-2) on the healing of full-thickness defects of articular cartilage. Journal of Bone and Joint Surgery 79-A(10): 1452-1463
25. Sellers RZR, Glasson S, Kim H, Peluso D, D'Augusta D, Beckwith K, Morris E (2000) Repair of articular cartilage defects one year after treatment with recombinant human bone morphogenetic protein-2 (rhBMP-2). Journal of Bone and Joint Surgery 82-A(2):151-160
26. Urist MR (1965) Bone: formation by autoinduction. Science 150(698):893-899
27. Van Beuningen HMGH, van der Kraan PM, van den Berg WB (1998) Differential effects of local application of BMP-2 or TGF-beta on both articular cartilage composition and osteophyte formation. Osteoarthritis and Cartilage 6:306-317
28. Yeh LCM-GF, Lee JC (2002) Differential effects of osteogenic protein-1 (BMP-7) on gene expression of BMP and GDF family members during differentiation on the mouse MC615 chondrocyte cells. Journal of Cell Physiology 191(3):298-309
29. Zeisberg MBC, Kumar N, Maeshima Y, Strutz F, Muller GA, Kalluri R (2003) Bone morphogenetic protein-7 inhibits progression of chronic renal fibrosis associated with two genetic mouse models. Am J Physiol Renal Physiol 285(6):F1060-F1067
30. Zhao GQ (2003) Consequences of knocking out BMP signaling in the mouse. Genesis 35(1):43-56