Endothelin B receptor-mediated protection against anoxia-reoxygenation injury in perfused rat liver: Nitric oxide-dependent and-independent mechanisms

Hepatology

Volumn 33, Issue 4, 2001, Pages 894-901

  Taniai, Hisashi ^a   Suematsu, Makoto ^b   Susuki, Tsuneharu ^b   Norimizu, Shinji ^b   Hori, Rio ^b   Ishimura, Yuzuru ^b   Nimura, Yuji ^c  

^a NAGOYA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b KEIO UNIVERSITY   (Japan)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

CLOTRIMAZOLE; CYCLIC GMP; CYTOCHROME P450 INHIBITOR; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; N ACETYL S NITROSOPENICILLAMINE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE INHIBITOR; PERHYDRO 1 AZEPINYLCARBONYLLEUCYL DEXTRO TRYPTOPHYL DEXTRO TRYPTOPHAN; PHOSPHOLIPID;

ANIMAL CELL; ANIMAL TISSUE; ANOXIA; ARTICLE; BILE FLOW; CONTROLLED STUDY; LIVER CELL DAMAGE; LIVER ISCHEMIA; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; REOXYGENATION;

EID: 0035086401     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1053/jhep.2001.23001     Document Type: Article

References (42)

1. The endothelin system. A new target for therapeutic intervention
2. Roles of endothelin-1 and nitric oxide in the mechanism for ethanol-induced vasoconstriction in rat liver
3. Vasoactive effect of endothelin-1 on rat liver in vivo
4. Hepatic lipocytes: A major target for endothelin-1
5. Inducible nitric oxide synthase in rat hepatic lipocytes and the effect of nitric oxide on lipocyte contractility
6. Endothelin receptors in rat liver: Lipocytes as a contractile target for endothelin 1
7. Molecular characterization of endothelin receptors
8. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells
9. Cytochrome P450 w/w-1 hydroxylase-derived eicosanoids contribute to endothelin A and endothelin B receptor-mediated vasoconstriction to endothelin-1 in the rat preglomerular arteriole
10. Analysis of two pharmacologically predicted endothelin B receptor subtypes by using the endothelin B receptor gene knockout mouse
11. Endotoxin pretreatment enhances portal venous contractile response to endothelin-1
12. Ischemia/reperfusion induces an increase in the hepatic portal vasoconstrictive response to endothelin-1
13. Endothelin 1 aggravates acute liver injury in perfused livers of rats after treatment with D-galactosamine
14. Contribution of endothelin-1 to microcirculatory impairment in total hepatic ischemia and reperfusion injury
15. Effects of selective and non-selective endothelin antagonists on ischemia-reperfusion damage in the isolated perfused murine liver
16. B receptor antagonist, in portal hypertensive rats
17. ET-1 induced alterations of hepatic microcirculation: Sinusoidal and extrasinusoidal sites of action
18. Endothelin-1 induces direct constriction of hepatic sinusoids
19. The contraction of hepatic stellate (Ito) cells stimulated with vasoactive substances. Possible involvement of endothelin 1 and nitric oxide in the regulation of the sinusoidal tonus
20. Carbon monoxide: An endogenous modulator of sinusoidal tone in the perfused rat liver
21. Distribution of heme oxygenase isoforms in rat liver: Topographic basis for carbon monoxide-mediated microvascular relaxation
22. Hypoxic damage generates reactive oxygen species in isolated perfused rat liver
23. An efficient preparation of the pseudopeptide endothelin-B receptor selective antagonist BQ-788
24. A receptor antagonist, BQ-485; and its preventive effect on experimental cerebral vasospasm in dogs
25. B2 receptors, BQ-788: Effects on blood vessel and small intestine
26. Use of the endothelin antagonists BQ-123 and PD 142893 to reveal three receptors mediating smooth muscle contraction and release EDRF
27. Carbon monoxide-mediated alterations in paracellular permeability and vesicular transport in acetaminophen-treated perfused rat liver
28. Superoxide radicals in feline intestinal ischemia
29. 2-release by activated Kupffer cells upon hypoxia-reoxygenation
30. Endothelin-1 stimulates bile acid secretion and vesicular transport in the isolated perfused rat liver
31. Endothelin-1 induces contraction of bile canaliculi in isolated rat hepatocytes
32. Uncoupling of biliary lipid from bile acid secretion by formyl-methionyl-leucyl-phenylalanine in the rat
33. Nitric oxide potently and reversibly deenergizes mitochondria at low oxygen tension
34. Nitric oxide suppression reversibly attenuates mitochondrial dysfunction and cholestasis in endotoxemic rat liver
35. Functional significance of endothelin B receptors in mediating sinusoidal and extrasinusoidal effects of endothelins in the intact rat liver
36. Protective role of NO in hepatic microcirculatory dysfunction during endotoxemia
37. Nitric oxide in liver injury
38. Kupffer cell-independent hepatocellular oxidative stress and decreased bile formation in post-cold-ischemic rat liver
39. Potent cyclo-oxygenase-mediated bronchoconstrictor effects of endothelin in the guinea-pig in vivo
40. Cytochrome P450 and cyclooxygenase metabolites contribute to the endothelin-1 afferent arteriolar vasoconstrictor and calcium responses
41. Liver sinusoidal endothelial cells are responsible for nitric oxide modulation of resistance in the hepatic sinusoids
42. Elevated blood pressure and craniofacial abnormalities in mice deficient in endothelin-1