A three-fluorophore FRET assay for high-throughput screening of small-molecule inhibitors of ribosome assembly

Nucleic Acids Research

Volumn 32, Issue 9, 2004, Pages 2707-2715

  Klostermeier, Dagmar ^a,b   Sears, Pamela ^a   Wong, Chi Huey ^a   Millar, David P ^a   Williamson, James R ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

^b UNIVERSITY OF BAYREUTH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GENTAMICIN; HYGROMYCIN; KANAMYCIN; NEAMINE; NEOMYCIN; PAROMOMYCIN; PROTEIN S15; RIBOSOME INACTIVATING PROTEIN; RIBOSOME PROTEIN; RNA 16S; STREPTOMYCIN; TOBRAMYCIN; UNCLASSIFIED DRUG; AMINOGLYCOSIDE; BACTERIAL RNA; FLUORESCENT DYE; MAGNESIUM; RIBOSOMAL PROTEIN S15;

ARTICLE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; DRUG SCREENING; DRUG STRUCTURE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HIGH THROUGHPUT SCREENING; MOLECULAR LIBRARY; NONHUMAN; PRIORITY JOURNAL; PROCESS MONITORING; PROTEIN ASSEMBLY; RNA BINDING; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; ESCHERICHIA COLI; FLUORESCENCE; GENETICS; METABOLISM; METHODOLOGY; RIBOSOME;

PROKARYOTA;

AMINOGLYCOSIDES; ESCHERICHIA COLI; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; FLUORESCENT DYES; MAGNESIUM; MOLECULAR STRUCTURE; NUCLEIC ACID CONFORMATION; RIBOSOMAL PROTEINS; RIBOSOMES; RNA, BACTERIAL; RNA, RIBOSOMAL, 16S;

EID: 2542601493     PISSN: 03051048     EISSN: None     Source Type: Journal    
DOI: 10.1093/nar/gkh588     Document Type: Article

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