Predicting human intestinal absorption from three-dimensional molecular structure of drugs

Acta Physico - Chimica Sinica

Volumn 20, Issue 5, 2004, Pages 512-517

  Hu, Gui Xiang ^a   Zou, Jian Wei ^a   Jiang, Yong Jun ^a   Wang, Yan Hua ^a   Yu, Qing Sen ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

Human intestinal absorption (HIA); Partial least squares (PLS); Principal component analysis (PCA); Three dimension; Volsurf

Indexed keywords

AMPHETAMINE; BUMETANIDE; CISAPRIDE; CODEINE; CYPROTERONE ACETATE; DICLOFENAC; DISULFIRAM; ETHINYLESTRADIOL; FLUCONAZOLE; FUROSEMIDE; IBUPROFEN; IMIPRAMINE; KETOPROFEN; LABETALOL; LAMOTRIGINE; LORMETAZEPAM; LORNOXICAM; MELOXICAM; NEFAZODONE; NORDAZEPAM; ONDANSETRON; OXATOMIDE; PROGESTERONE; SALICYLIC ACID; SUDOXICAM; THEOPHYLLINE; TRANEXAMIC ACID; TRAPIDIL; UNINDEXED DRUG; ZIDOVUDINE;

ARTICLE; CORRELATION ANALYSIS; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG EXCRETION; DRUG FECES LEVEL; DRUG URINE LEVEL; HUMAN; HYDROGEN BOND; HYDROPHILICITY; HYDROPHOBICITY; INTESTINE ABSORPTION; PREDICTION;

EID: 2542598608     PISSN: 10006818     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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