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Volumn 142, Issue 1, 2004, Pages 107-112

I f channel inhibitor ivabradine lowers heart rate in mice with enhanced sympathoadrenergic activities

Author keywords

Echocardiography; Sinus node inhibitor; Sympathetic nervous system; Transgenic mice

Indexed keywords

BETA 2 ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; ISOPRENALINE; IVABRADINE;

EID: 2542527721     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0705696     Document Type: Article
Times cited : (45)

References (35)
  • 1
    • 0029744373 scopus 로고    scopus 로고
    • Mode of action of bradycardic agent, S 16257, on ionic currents of rabbit sinoatrial node cells
    • BOIS, P., BESCOND, J., RENAUDON, B. & LENFANT, J. (1996). Mode of action of bradycardic agent, S 16257, on ionic currents of rabbit sinoatrial node cells. Br. J. Pharmacol., 118, 1051-1057.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1051-1057
    • Bois, P.1    Bescond, J.2    Renaudon, B.3    Lenfant, J.4
  • 3
    • 0037448788 scopus 로고    scopus 로고
    • f inhibitor, in stable angina: A randomized, double-blind, multicentered, placebo-controlled trial
    • f inhibitor, in stable angina: a randomized, double-blind, multicentered, placebo-controlled trial. Circulation, 107, 817-823.
    • (2003) Circulation , vol.107 , pp. 817-823
    • Borer, J.S.1    Fox, K.2    Jaillon, P.3    Lerebours, G.4
  • 4
    • 0033937122 scopus 로고    scopus 로고
    • Mechanistic and clinical rationales for using β-blockers in heart failure
    • BRISTOW, M. (2000). Mechanistic and clinical rationales for using β-blockers in heart failure. J. Card Fail., 6 (Suppl 1), 8-14.
    • (2000) J. Card Fail. , vol.6 , Issue.1 SUPPL. , pp. 8-14
    • Bristow, M.1
  • 6
    • 0025817912 scopus 로고
    • Dysfunction of the β- and α-adrenergic systems in a model of congestive heart failure. The pacing-overdrive dog
    • CALDERONE, A., BOUVIER, M., LI, K., JUNEAU, C., DE CHAMPLAIN, J. & ROULEAU, J.L. (1991). Dysfunction of the β- and α-adrenergic systems in a model of congestive heart failure. The pacing-overdrive dog. Circ. Res., 69, 332-343.
    • (1991) Circ. Res. , vol.69 , pp. 332-343
    • Calderone, A.1    Bouvier, M.2    Li, K.3    Juneau, C.4    De Champlain, J.5    Rouleau, J.L.6
  • 7
    • 0042357093 scopus 로고    scopus 로고
    • Electrophysiological effects of a single intravenous administration of ivabradine (s 16257) in adult patients with normal baseline electrophysiology
    • CAMM, A. & LAU, C. (2003). Electrophysiological effects of a single intravenous administration of ivabradine (s 16257) in adult patients with normal baseline electrophysiology. Drugs Res. Dev., 4, 83-89.
    • (2003) Drugs Res. Dev. , vol.4 , pp. 83-89
    • Camm, A.1    Lau, C.2
  • 10
    • 0025148202 scopus 로고
    • Abnormalities of peripheral sympathetic nervous system control in congestive heart failure
    • COHN, J.N. (1990). Abnormalities of peripheral sympathetic nervous system control in congestive heart failure. Circulation, 82, 159-167.
    • (1990) Circulation , vol.82 , pp. 159-167
    • Cohn, J.N.1
  • 11
    • 0036089596 scopus 로고    scopus 로고
    • Differential effects of heart rate reduction and β-blockade on left ventricular relaxation during exercise
    • COLIN, P., GHALEH, B., HITTINGER, L., MONNET, X., SLAMA, M., GIUDICELLI, J.F. & BERDEAUX, A. (2002). Differential effects of heart rate reduction and β-blockade on left ventricular relaxation during exercise. Am. J. Physiol., 282, H672-H679.
    • (2002) Am. J. Physiol. , vol.282
    • Colin, P.1    Ghaleh, B.2    Hittinger, L.3    Monnet, X.4    Slama, M.5    Giudicelli, J.F.6    Berdeaux, A.7
  • 12
    • 0025977991 scopus 로고
    • f) to generation of spontaneous activity in rabbit sino-atrial node myocytes
    • f) to generation of spontaneous activity in rabbit sino-atrial node myocytes. J. Physiol., 434, 23-40.
    • (1991) J. Physiol. , vol.434 , pp. 23-40
    • Difrancesco, D.1
  • 13
    • 0029153291 scopus 로고
    • f) plays an important role in regulating SA node pacemaker activity
    • f) plays an important role in regulating SA node pacemaker activity. Cardiovasc. Res., 30, 307-308.
    • (1995) Cardiovasc. Res. , vol.30 , pp. 307-308
    • Difrancesco, D.1
  • 14
    • 0024598929 scopus 로고
    • Muscarinic modulation of cardiac rate at low acetylcholine concentrations
    • DIFRANCESCO, D., DUCOURET, P. & ROBINSON, R.B. (1989). Muscarinic modulation of cardiac rate at low acetylcholine concentrations. Science, 243, 669-671.
    • (1989) Science , vol.243 , pp. 669-671
    • Difrancesco, D.1    Ducouret, P.2    Robinson, R.B.3
  • 15
    • 0025782740 scopus 로고
    • Direct activation of cardiac pacemaker channels by intracellular cyclic AMP
    • DIFRANCESCO, D. & TORTORA, P. (1991). Direct activation of cardiac pacemaker channels by intracellular cyclic AMP. Nature, 351, 145-147.
    • (1991) Nature , vol.351 , pp. 145-147
    • Difrancesco, D.1    Tortora, P.2
  • 20
    • 0033984947 scopus 로고    scopus 로고
    • Serial echocardiographic assessment of left ventricular dimensions and function after myocardial infarction in mice
    • GAO, X.M., DART, A.M., DEWAR, E., JENNINGS, G. & DU, X.J. (2000). Serial echocardiographic assessment of left ventricular dimensions and function after myocardial infarction in mice. Cardiovasc. Res., 45, 330-338.
    • (2000) Cardiovasc. Res. , vol.45 , pp. 330-338
    • Gao, X.M.1    Dart, A.M.2    Dewar, E.3    Jennings, G.4    Du, X.J.5
  • 21
    • 0029056664 scopus 로고
    • Acute and chronic cardiac and regional haemodynamic effects of the novel bradycardic agent, S16257, in conscious rats
    • GARDINER, S.M., KEMP, P.A., MARCH, J.E. & BENNETT, T. (1995). Acute and chronic cardiac and regional haemodynamic effects of the novel bradycardic agent, S16257, in conscious rats. Br. J. Pharmacol., 115, 579-586.
    • (1995) Br. J. Pharmacol. , vol.115 , pp. 579-586
    • Gardiner, S.M.1    Kemp, P.A.2    March, J.E.3    Bennett, T.4
  • 22
    • 0028979091 scopus 로고
    • f current mediates β-adrenergic enhancement of heart rate but not contractility in vivo
    • f current mediates β-adrenergic enhancement of heart rate but not contractility in vivo. Basic Res. Cardiol., 90, 192-202.
    • (1995) Basic Res. Cardiol. , vol.90 , pp. 192-202
    • Guth, B.D.1    Dietze, T.2
  • 25
    • 0032553504 scopus 로고    scopus 로고
    • Determination of ivabradine and its N-demethylated metabolite in human plasma and urine, and in rat and dog plasma by a validated high-performance liquid chromatographic method with fluorescence detection
    • KLIPPERT, P., JEANNIOT, J.P., POLVE, S., LEFEVRE, C. & MERDJAN, H. (1998). Determination of ivabradine and its N-demethylated metabolite in human plasma and urine, and in rat and dog plasma by a validated high-performance liquid chromatographic method with fluorescence detection. J. Chromatogr. B Biomed. Sci. Appl., 719, 125-133.
    • (1998) J. Chromatogr. B Biomed. Sci. Appl. , vol.719 , pp. 125-133
    • Klippert, P.1    Jeanniot, J.P.2    Polve, S.3    Lefevre, C.4    Merdjan, H.5
  • 28
    • 0035192922 scopus 로고    scopus 로고
    • Effects of heart rate reduction with ivabradine on exercise-induced myocardial ischemia and stunning
    • MONNET, X., GHALEH, B., COLIN, P., DE CURZON, O.P., GIUDICELLI, J.F. & BERDEAUX, A. (2001). Effects of heart rate reduction with ivabradine on exercise-induced myocardial ischemia and stunning. J. Pharmacol. Exp. Ther., 299, 1133-1139.
    • (2001) J. Pharmacol. Exp. Ther. , vol.299 , pp. 1133-1139
    • Monnet, X.1    Ghaleh, B.2    Colin, P.3    De Curzon, O.P.4    Giudicelli, J.F.5    Berdeaux, A.6
  • 31
    • 0029937949 scopus 로고    scopus 로고
    • The effect of carvedilol on morbidity and mortality in patients with chronic heart failure
    • U.S. Carvedilol Heart Failure Study Group
    • PACKER, M., BRISTOW, M.R., COHN, J.N., COLUCCI, W.S., FOWLER, M.B., GILBERT, E.M. & SHUSTERMAN, N.H. (1996). The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group. N. Engl. J. Med., 334, 1349-1355.
    • (1996) N. Engl. J. Med. , vol.334 , pp. 1349-1355
    • Packer, M.1    Bristow, M.R.2    Cohn, J.N.3    Colucci, W.S.4    Fowler, M.B.5    Gilbert, E.M.6    Shusterman, N.H.7
  • 32
    • 0029582832 scopus 로고
    • Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs
    • SIMON, L., GHALEH, B., PUYBASSET, L., GIUDICELLI, J.F. & BERDEAUX, A. (1995). Coronary and hemodynamic effects of S 16257, a new bradycardic agent, in resting and exercising conscious dogs. J. Pharmacol. Exp. Ther., 275, 659-666.
    • (1995) J. Pharmacol. Exp. Ther. , vol.275 , pp. 659-666
    • Simon, L.1    Ghaleh, B.2    Puybasset, L.3    Giudicelli, J.F.4    Berdeaux, A.5
  • 34
    • 0028358379 scopus 로고
    • Electrophysiological effects of S 16257, a novel sino-atrial node modulator, on rabbit and guinea-pig cardiac preparations: Comparison with UL-FS 49
    • THOLLON, C., CAMBARRAT, C., VIAN, J., PROST, J.F., PEGLION, J.L. & VILAINE, J.P. (1994). Electrophysiological effects of S 16257, a novel sino-atrial node modulator, on rabbit and guinea-pig cardiac preparations: comparison with UL-FS 49. Br. J. Pharmacol., 112, 37-42.
    • (1994) Br. J. Pharmacol. , vol.112 , pp. 37-42
    • Thollon, C.1    Cambarrat, C.2    Vian, J.3    Prost, J.F.4    Peglion, J.L.5    Vilaine, J.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.