Accelerated cardiomyopathy in mice with overexpression of cardiac Gsα and a missense mutation in the α-myosin heavy chain

Circulation

Volumn 105, Issue 5, 2002, Pages 614-620

  Hardt, Stefan E ^a   Geng, Yong Jian ^a   Montagne, Olivier ^a   Asai, Kuniya ^a   Hong, Chull ^a   Yang, Gui Ping ^a   Bishop, Sanford P ^a   Kim, Song Jung ^a   Vatner, Dorothy E ^a   Seidman, Christine E ^a   Seidman, J G ^a   Homcy, Charles J ^a   Vatner, Stephen F ^a  

^a RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

Author keywords

Cardiomyopathy; Heart failure; Hypertrophy

Indexed keywords

BETA ADRENERGIC RECEPTOR; ISOPRENALINE; MYOSIN HEAVY CHAIN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA ADRENERGIC STIMULATION; CONTROLLED STUDY; ECHOCARDIOGRAPHY; FAMILIAL DISEASE; GENE OVEREXPRESSION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE PRESSURE; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEART RATE; HISTOPATHOLOGY; HYPERTROPHIC CARDIOMYOPATHY; MISSENSE MUTATION; MOUSE; NEWBORN; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; TRANSGENIC MOUSE;

ANIMALS; BODY WEIGHT; CARDIOMYOPATHY, HYPERTROPHIC, FAMILIAL; CELL SEPARATION; CROSSES, GENETIC; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; ECHOCARDIOGRAPHY; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; HEART RATE; MICE; MICE, TRANSGENIC; MUTATION, MISSENSE; MYOCARDIAL CONTRACTION; MYOCARDIUM; MYOSIN HEAVY CHAINS; ORGAN SIZE; STROKE VOLUME; SURVIVAL RATE; VENTRICULAR FUNCTION, LEFT;

EID: 0037022232     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/hc0502.103012     Document Type: Article

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