Transient and reversible deoxyribonucleic acid damage in human left ventricle under controlled ischemia and reperfusion

Journal of the American College of Cardiology

Volumn 43, Issue 11, 2004, Pages 1992-1999

  Corbucci, Gian G ^a   Perrino, Cinzia ^b   Donato, Giuseppe ^b   Ricchi, Antonio ^c   Lettieri, Biagio ^c   Troncone, Giancarlo ^d   Indolfi, Ciro ^e   Chiariello, Massimo ^b   Avvedimento, Enrico V ^b,d  

^a UNIVERSITY OF CAGLIARI   (Italy)

^b UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^d BROTZU HOSPITAL   (Italy)

^e SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

COX; cytochrome c oxidase; deoxyribonucleic acid; DNA; electron microscopy; EM; ERK; extracellular signal regulated kinase; JNK; Jun terminal kinase; PCNA; proliferative cell nuclear antigen; reactive oxygen species; ROS

Indexed keywords

ATM PROTEIN; CELL NUCLEUS ANTIGEN; DNA; MITOGEN ACTIVATED PROTEIN KINASE 1; PROTEIN P21; PROTEIN P53; STRESS ACTIVATED PROTEIN KINASE;

ADULT; AGED; AORTA CLAMPING; ARTICLE; CELL PROLIFERATION; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BLOOD FLOW; DNA RESPONSIVE ELEMENT; DNA STRAND BREAKAGE; ELECTIVE SURGERY; ELECTRON MICROSCOPY; ENZYME ACTIVATION; ENZYME SUBSTRATE; FEMALE; HEART CONTRACTION; HEART LEFT VENTRICLE; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; HEART VALVE SURGERY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; MALE; METABOLIC ACTIVATION; MITOCHONDRION SWELLING; NICK END LABELING; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; STUNNED HEART MUSCLE; TISSUE SECTION;

ADENOSINE TRIPHOSPHATE; ADULT; AGED; BLOTTING, WESTERN; DNA DAMAGE; ELECTRON TRANSPORT COMPLEX IV; FEMALE; HEART VENTRICLES; HUMANS; IN SITU NICK-END LABELING; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; REACTIVE OXYGEN SPECIES;

EID: 2542478761     PISSN: 07351097     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jacc.2004.01.040     Document Type: Article

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