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Volumn 103, Issue 11, 2004, Pages 4232-4239

Thymosin α 1 activates dendritic cells for antifungal Th1 resistance through Toll-like receptor signaling

Author keywords

[No Author keywords available]

Indexed keywords

A 2942; AMPHOTERICIN B; CYCLOPHOSPHAMIDE; GRANULOCYTE COLONY STIMULATING FACTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 12; MITOGEN ACTIVATED PROTEIN KINASE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; THYMOSIN ALPHA1; THYMUS PEPTIDE; TOLL LIKE RECEPTOR;

EID: 2542451903     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-11-4036     Document Type: Article
Times cited : (192)

References (50)
  • 1
    • 0001808479 scopus 로고    scopus 로고
    • Aspergillus
    • Mandel GL, Bennett JE, Dolin R, eds. Philadelphia, PA: Saunders
    • Denning DW. Aspergillus. In: Mandel GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. Philadelphia, PA: Saunders; 2000:2674-2682.
    • (2000) Principles and Practice of Infectious Diseases , pp. 2674-2682
    • Denning, D.W.1
  • 2
    • 0037114705 scopus 로고    scopus 로고
    • Invasive aspergillosis in allogeneic stem cell transplant recipients: Changes in epidemiology and risk factors
    • Marr KA, Carter RA, Boeckh M, Martin P, Corey L. Invasive aspergillosis in allogeneic stem cell transplant recipients: changes in epidemiology and risk factors. Blood. 2002;100:4358-4366.
    • (2002) Blood , vol.100 , pp. 4358-4366
    • Marr, K.A.1    Carter, R.A.2    Boeckh, M.3    Martin, P.4    Corey, L.5
  • 3
    • 0033856265 scopus 로고    scopus 로고
    • Invasive aspergillosis. Disease spectrum, treatment practices, and outcomes
    • Patterson TF, Kirkpatrick WR, White M, et al. Invasive aspergillosis. Disease spectrum, treatment practices, and outcomes. Medicine. 2000;79:250-260.
    • (2000) Medicine , vol.79 , pp. 250-260
    • Patterson, T.F.1    Kirkpatrick, W.R.2    White, M.3
  • 4
    • 0037114640 scopus 로고    scopus 로고
    • Myeloid progenitors protect against aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation
    • BitMansour A, Burns SM, Traver D, et al. Myeloid progenitors protect against aspergillosis and Pseudomonas aeruginosa infection following hematopoietic stem cell transplantation. Blood. 2002;100:4660-4667.
    • (2002) Blood , vol.100 , pp. 4660-4667
    • BitMansour, A.1    Burns, S.M.2    Traver, D.3
  • 5
    • 0037114694 scopus 로고    scopus 로고
    • Analysis of T-cell responses to Aspergillus fumigatus antigens in healthy individuals and patients with hematological malignancies
    • Hebart H, Bollinger C, Fisch P, et al. Analysis of T-cell responses to Aspergillus fumigatus antigens in healthy individuals and patients with hematological malignancies. Blood. 2002;100:4521-4527.
    • (2002) Blood , vol.100 , pp. 4521-4527
    • Hebart, H.1    Bollinger, C.2    Fisch, P.3
  • 7
    • 0034234612 scopus 로고    scopus 로고
    • T cell vaccination in mice with invasive pulmonary aspergillosis
    • Cenci E, Mencacci A, Bacci A, et al. T cell vaccination in mice with invasive pulmonary aspergillosis. J Immunol. 2000;165:381-388.
    • (2000) J Immunol , vol.165 , pp. 381-388
    • Cenci, E.1    Mencacci, A.2    Bacci, A.3
  • 8
    • 18744372691 scopus 로고    scopus 로고
    • Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response
    • Garlanda C, Hirsch E, Bozza S, et al. Non-redundant role of the long pentraxin PTX3 in anti-fungal innate immune response. Nature. 2002;420:182-186.
    • (2002) Nature , vol.420 , pp. 182-186
    • Garlanda, C.1    Hirsch, E.2    Bozza, S.3
  • 10
    • 0036467527 scopus 로고    scopus 로고
    • Dendritic cells transport conidia and hyphae of Aspergillus fumigatus from the airways to the draining lymph nodes and initiate disparate Th responses to the fungus
    • Bozza S, Gaziano R, Spreca A, et al. Dendritic cells transport conidia and hyphae of Aspergillus fumigatus from the airways to the draining lymph nodes and initiate disparate Th responses to the fungus. J Immunol. 2002;168:1362-1371.
    • (2002) J Immunol , vol.168 , pp. 1362-1371
    • Bozza, S.1    Gaziano, R.2    Spreca, A.3
  • 11
    • 0036848617 scopus 로고    scopus 로고
    • Vaccination of mice against invasive aspergillosis with recombinant Aspergillus proteins and CpG oligodeoxynucleotides as adjuvants
    • Bozza S, Gaziano R, Lipford GB, et al. Vaccination of mice against invasive aspergillosis with recombinant Aspergillus proteins and CpG oligodeoxynucleotides as adjuvants. Microbes Infect. 2002;4:1281-1290.
    • (2002) Microbes Infect , vol.4 , pp. 1281-1290
    • Bozza, S.1    Gaziano, R.2    Lipford, G.B.3
  • 12
    • 0035085495 scopus 로고    scopus 로고
    • Involvement of CD14 and toll-like receptors inactivation of human monocytes by Aspergillus fumigatus hyphae
    • Wang JE, Warris A, Ellingsen EA, et al. Involvement of CD14 and toll-like receptors inactivation of human monocytes by Aspergillus fumigatus hyphae. Infect Immun. 2001;69:2402-2406.
    • (2001) Infect Immun , vol.69 , pp. 2402-2406
    • Wang, J.E.1    Warris, A.2    Ellingsen, E.A.3
  • 13
    • 0037131427 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus
    • Mambula SS, Sau K, Henneke P, Golenbock DT, Levitz SM. Toll-like receptor (TLR) signaling in response to Aspergillus fumigatus. J Biol Chem. 2002;277:39320-39326.
    • (2002) J Biol Chem , vol.277 , pp. 39320-39326
    • Mambula, S.S.1    Sau, K.2    Henneke, P.3    Golenbock, D.T.4    Levitz, S.M.5
  • 14
    • 0036083905 scopus 로고    scopus 로고
    • Exploiting dendritic cells to improve vaccine efficacy
    • Steinman RM, Pope M. Exploiting dendritic cells to improve vaccine efficacy. J Clin Invest. 2002;109:1519-1526.
    • (2002) J Clin Invest , vol.109 , pp. 1519-1526
    • Steinman, R.M.1    Pope, M.2
  • 15
    • 0032695108 scopus 로고    scopus 로고
    • Natural adjuvants: Endogenous activators of dendritic cells
    • Gallucci S, Lolkema M, Matzinger P. Natural adjuvants: endogenous activators of dendritic cells. Nat Med. 1999;5:1249-1255.
    • (1999) Nat Med , vol.5 , pp. 1249-1255
    • Gallucci, S.1    Lolkema, M.2    Matzinger, P.3
  • 16
    • 18044402279 scopus 로고    scopus 로고
    • Making smarter immunotherapies
    • Ibrahim MA, Gotch FM. Making smarter immunotherapies (letter). Nat Immunol. 2000;1:3.
    • (2000) Nat Immunol , vol.1 , pp. 3
    • Ibrahim, M.A.1    Gotch, F.M.2
  • 18
    • 0036557949 scopus 로고    scopus 로고
    • Thymosin alpha1, SciClone Pharmaceuticals
    • Billich A. Thymosin alpha1, SciClone Pharmaceuticals. Curr Opin Investig Drugs. 2002;3:698-707.
    • (2002) Curr Opin Investig Drugs , vol.3 , pp. 698-707
    • Billich, A.1
  • 19
    • 0030452149 scopus 로고    scopus 로고
    • Combination thymosin alpha 1 and lymphoblastoid interferon treatment in chronic hepatitis C
    • Rasi G, DiVirgilio D, Mutchnick MG, et al. Combination thymosin alpha 1 and lymphoblastoid interferon treatment in chronic hepatitis C. Gut. 1996;39:679-683.
    • (1996) Gut , vol.39 , pp. 679-683
    • Rasi, G.1    DiVirgilio, D.2    Mutchnick, M.G.3
  • 20
    • 0016430975 scopus 로고
    • Thymosin activity in patients with cellular immunodeficiency
    • Wara DW, Goldstein AL, Doyle NE, Amman AJ. Thymosin activity in patients with cellular immunodeficiency. N Engl J Med. 1975;292:70-74.
    • (1975) N Engl J Med , vol.292 , pp. 70-74
    • Wara, D.W.1    Goldstein, A.L.2    Doyle, N.E.3    Amman, A.J.4
  • 21
    • 0034535749 scopus 로고    scopus 로고
    • Thymosin alpha 1 in the treatment of cancer: From basic research to clinical application
    • Garaci E, Pica F, Rasi G, Favalli C. Thymosin alpha 1 in the treatment of cancer: from basic research to clinical application. Int J Immunopharmacol. 2000;22:1067-1076.
    • (2000) Int J Immunopharmacol , vol.22 , pp. 1067-1076
    • Garaci, E.1    Pica, F.2    Rasi, G.3    Favalli, C.4
  • 22
    • 0020083433 scopus 로고
    • Increase of mouse resistance to Candida albicans infection by thymosin al
    • Bistoni F, Marconi P, Frati L, Bonmassar E, Garaci E. Increase of mouse resistance to Candida albicans infection by thymosin al. Infect Immun. 1982;36:609-614.
    • (1982) Infect Immun , vol.36 , pp. 609-614
    • Bistoni, F.1    Marconi, P.2    Frati, L.3    Bonmassar, E.4    Garaci, E.5
  • 23
    • 0035192088 scopus 로고    scopus 로고
    • Involvement of mitogen-activated protein kinases in the signal transduction pathway of bone marrow-derived macrophage activation in response to in vitro treatment with thymosin alpha 1
    • Sodhi A, Paul S. Involvement of mitogen-activated protein kinases in the signal transduction pathway of bone marrow-derived macrophage activation in response to in vitro treatment with thymosin alpha 1. Int Immunopharmacol. 2002;2:47-58.
    • (2002) Int Immunopharmacol , vol.2 , pp. 47-58
    • Sodhi, A.1    Paul, S.2
  • 24
    • 0033621845 scopus 로고    scopus 로고
    • Thymosin-alphal regulates MHC class I expression in FRTL-5 cells at transcriptional level
    • Giuliani C, Napolitano G, Mastino A, et al. Thymosin-alphal regulates MHC class I expression in FRTL-5 cells at transcriptional level. Eur J Immunol. 2000;30:778-786.
    • (2000) Eur J Immunol , vol.30 , pp. 778-786
    • Giuliani, C.1    Napolitano, G.2    Mastino, A.3
  • 25
    • 0035282931 scopus 로고    scopus 로고
    • Defective anti-fungal T-helper 1 (TH1) immunity in a murine model of allogeneic T-cell-depleted bone marrow transplantation and its restoration by treatment with TH2 cytokine antagonists
    • Mencacci A, Perruccio K, Bacci A, et al. Defective anti-fungal T-helper 1 (TH1) immunity in a murine model of allogeneic T-cell-depleted bone marrow transplantation and its restoration by treatment with TH2 cytokine antagonists. Blood. 2001;97:1483-1490.
    • (2001) Blood , vol.97 , pp. 1483-1490
    • Mencacci, A.1    Perruccio, K.2    Bacci, A.3
  • 26
    • 0035903288 scopus 로고    scopus 로고
    • Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens
    • Kadowaki N, Ho S, Antonenko S, et al. Subsets of human dendritic cell precursors express different toll-like receptors and respond to different microbial antigens. J Exp Med. 2001;194:863-869.
    • (2001) J Exp Med , vol.194 , pp. 863-869
    • Kadowaki, N.1    Ho, S.2    Antonenko, S.3
  • 27
    • 10744219675 scopus 로고    scopus 로고
    • TLR9 signals after translocating from ER to CpG DNA in the lysosome
    • Latz E, Schoenemeyer A, Visintin A, et al. TLR9 signals after translocating from ER to CpG DNA in the lysosome. Nat Med. 2004;5:190-198.
    • (2004) Nat Med , vol.5 , pp. 190-198
    • Latz, E.1    Schoenemeyer, A.2    Visintin, A.3
  • 28
    • 0036136335 scopus 로고    scopus 로고
    • Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages
    • Sweet MJ, Campbell CC, Sester DP, et al. Colony-stimulating factor-1 suppresses responses to CpG DNA and expression of toll-like receptor 9 but enhances responses to lipopolysaccharide in murine macrophages. J Immunol. 2002;168:392-399.
    • (2002) J Immunol , vol.168 , pp. 392-399
    • Sweet, M.J.1    Campbell, C.C.2    Sester, D.P.3
  • 29
    • 0034670044 scopus 로고    scopus 로고
    • Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: Phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression
    • Chen CH, Zhang DH, La Porte JM, Ray A. Cyclic AMP activates p38 mitogen-activated protein kinase in Th2 cells: phosphorylation of GATA-3 and stimulation of Th2 cytokine gene expression. J Immunol. 2000;165:5597-5605.
    • (2000) J Immunol , vol.165 , pp. 5597-5605
    • Chen, C.H.1    Zhang, D.H.2    La Porte, J.M.3    Ray, A.4
  • 30
    • 0033546053 scopus 로고    scopus 로고
    • The nature of the principal type I interferon-producing cells in human blood
    • Siegal FP, Kadowaki N, Shodell M, et al. The nature of the principal type I interferon-producing cells in human blood. Science. 1999;284:1835-1837.
    • (1999) Science , vol.284 , pp. 1835-1837
    • Siegal, F.P.1    Kadowaki, N.2    Shodell, M.3
  • 31
    • 0034886143 scopus 로고    scopus 로고
    • Toll-like receptors: Critical proteins linking innate and acquired immunity
    • Akira S, Takeda K, Kaisho T. Toll-like receptors: critical proteins linking innate and acquired immunity. Nat Immunol. 2001;2:675-680.
    • (2001) Nat Immunol , vol.2 , pp. 675-680
    • Akira, S.1    Takeda, K.2    Kaisho, T.3
  • 33
    • 0029006149 scopus 로고
    • Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence
    • Lin YZ, Yao SY, Veach RA, Torgerson TR, Hawiger J. Inhibition of nuclear translocation of transcription factor NF-kappa B by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J Biol Chem. 1995;270:14255-14258.
    • (1995) J Biol Chem , vol.270 , pp. 14255-14258
    • Lin, Y.Z.1    Yao, S.Y.2    Veach, R.A.3    Torgerson, T.R.4    Hawiger, J.5
  • 34
    • 0033538498 scopus 로고    scopus 로고
    • One-way cross-talk between p38 (MAPK) and p42/44 (MAPK): Inhibition of p38 (MAPK) induces low density lipoprotein receptor expression through activation of the p42/44 (MAPK) cascade
    • Singh RP, Dhawan P, Golden C, Kapoor GS, Metha KD. One-way cross-talk between p38 (MAPK) and p42/44 (MAPK): inhibition of p38 (MAPK) induces low density lipoprotein receptor expression through activation of the p42/44 (MAPK) cascade. J Biol Chem. 1999;270:19593-19600.
    • (1999) J Biol Chem , vol.270 , pp. 19593-19600
    • Singh, R.P.1    Dhawan, P.2    Golden, C.3    Kapoor, G.S.4    Metha, K.D.5
  • 35
    • 0036786447 scopus 로고    scopus 로고
    • Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering
    • Edwards AD, Manickasingham SP, Spom R, et al. Microbial recognition via Toll-like receptor-dependent and -independent pathways determines the cytokine response of murine dendritic cell subsets to CD40 triggering. J Immunol. 2002;169:3652-3660.
    • (2002) J Immunol , vol.169 , pp. 3652-3660
    • Edwards, A.D.1    Manickasingham, S.P.2    Spom, R.3
  • 36
    • 0036534871 scopus 로고    scopus 로고
    • The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor
    • Gilliet M, Boonstra A, Paturel C, et al. The development of murine plasmacytoid dendritic cell precursors is differentially regulated by FLT3-ligand and granulocyte/macrophage colony-stimulating factor. J Exp Med. 2002;195:953-958.
    • (2002) J Exp Med , vol.195 , pp. 953-958
    • Gilliet, M.1    Boonstra, A.2    Paturel, C.3
  • 37
    • 0035253732 scopus 로고    scopus 로고
    • MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to Gram-positive and Gram-negative bacteria and their cell wall components
    • Dziarski R, Wang Q, Miyake K, Kirshning CJ, Gupta D. MD-2 enables Toll-like receptor 2 (TLR2)-mediated responses to lipopolysaccharide and enhances TLR2-mediated responses to Gram-positive and Gram-negative bacteria and their cell wall components. J Immunol. 2001;166:1938-1944.
    • (2001) J Immunol , vol.166 , pp. 1938-1944
    • Dziarski, R.1    Wang, Q.2    Miyake, K.3    Kirshning, C.J.4    Gupta, D.5
  • 38
    • 0032435181 scopus 로고    scopus 로고
    • The conformation of peptide thymosin α 1 in solution and in membrane-like environment by circular dicroism and NMR spectroscopy: A possible model for its interaction with the lymphocyte membrane
    • Grottesi A, Sette M, Palamara AT, Rotilio G, Garaci E, Paci M. The conformation of peptide thymosin α 1 in solution and in membrane-like environment by circular dicroism and NMR spectroscopy: a possible model for its interaction with the lymphocyte membrane. Peptides. 1998;19:1731-1738.
    • (1998) Peptides , vol.19 , pp. 1731-1738
    • Grottesi, A.1    Sette, M.2    Palamara, A.T.3    Rotilio, G.4    Garaci, E.5    Paci, M.6
  • 39
    • 0036844493 scopus 로고    scopus 로고
    • Fungi, dendritic cells and receptors: A host perspective of fungal virulence
    • Romani L, Bistoni F, Puccetti P. Fungi, dendritic cells and receptors: a host perspective of fungal virulence. Trends Microblol. 2002;10:508-514.
    • (2002) Trends Microblol , vol.10 , pp. 508-514
    • Romani, L.1    Bistoni, F.2    Puccetti, P.3
  • 40
    • 0034353201 scopus 로고    scopus 로고
    • Thymosin alpha 1 is a time and dose-dependent antagonist of dexamethasone-induced apoptosis of murine thymocytes in vitro
    • Baumann CA, Badamchian M, Goldstein AL. Thymosin alpha 1 is a time and dose-dependent antagonist of dexamethasone-induced apoptosis of murine thymocytes in vitro. Int J Immunopharmacol. 2000;22:1057-1066.
    • (2000) Int J Immunopharmacol , vol.22 , pp. 1057-1066
    • Baumann, C.A.1    Badamchian, M.2    Goldstein, A.L.3
  • 42
    • 0030948056 scopus 로고    scopus 로고
    • Interferons alpha/ beta and their receptors: Place in the hierarchy of cytokines
    • Zav'Yalov VP, Zav'Yalova GA. Interferons alpha/ beta and their receptors: place in the hierarchy of cytokines. APMIS. 1997;3:161-186.
    • (1997) APMIS , vol.3 , pp. 161-186
    • Zav'Yalov, V.P.1    Zav'Yalova, G.A.2
  • 43
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: Specialized and regulated antigen-processing machines
    • Mellmann I, Steinman RM. Dendritic cells: specialized and regulated antigen-processing machines. Cell. 2001;106:255-258.
    • (2001) Cell , vol.106 , pp. 255-258
    • Mellmann, I.1    Steinman, R.M.2
  • 45
    • 0038306841 scopus 로고    scopus 로고
    • Prothymosin alpha is processed to thymosin alpha 1 and thymosin alpha 11 by a lysosomal asparaginyl endopeptidase
    • Sarandeses CS, Covelo G, Diaz-Jullien C, Freire M. Prothymosin alpha is processed to thymosin alpha 1 and thymosin alpha 11 by a lysosomal asparaginyl endopeptidase. J Biol Chem. 2003;273:13286-13293.
    • (2003) J Biol Chem , vol.273 , pp. 13286-13293
    • Sarandeses, C.S.1    Covelo, G.2    Diaz-Jullien, C.3    Freire, M.4
  • 46
    • 0042123694 scopus 로고    scopus 로고
    • Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells
    • Lund J, Sato A, Akira S, Medzhitov R, Iwasaki A. Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells. J Exp Med. 2003;198:513-520.
    • (2003) J Exp Med , vol.198 , pp. 513-520
    • Lund, J.1    Sato, A.2    Akira, S.3    Medzhitov, R.4    Iwasaki, A.5
  • 47
    • 0034304003 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization
    • Cella M, Facchetti F, Lanzavecchia A, Colonna M. Plasmacytoid dendritic cells activated by influenza virus and CD40L drive a potent TH1 polarization. Nat Immunol. 2000;1:305-310.
    • (2000) Nat Immunol , vol.1 , pp. 305-310
    • Cella, M.1    Facchetti, F.2    Lanzavecchia, A.3    Colonna, M.4
  • 48
    • 0037128167 scopus 로고    scopus 로고
    • Interferon α/β and interleukin 12 responses to viral infections: Pathways regulating dendritic cell cytokine expression in vivo
    • Dalod M, Salazar-Mather TP, Malmgaard L, et al. Interferon α/ β and interleukin 12 responses to viral infections: pathways regulating dendritic cell cytokine expression in vivo. J Exp Med. 2002;195:517-528.
    • (2002) J Exp Med , vol.195 , pp. 517-528
    • Dalod, M.1    Salazar-Mather, T.P.2    Malmgaard, L.3
  • 49
    • 0036926445 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells: Do they have a role in immune responses after hematopoietic cell transplantation?
    • Rossi M, Arpinati M, Rondelli D, Anasetti C. Plasmacytoid dendritic cells: do they have a role in immune responses after hematopoietic cell transplantation? Hum Immunol. 2002;63:1194-1200.
    • (2002) Hum Immunol , vol.63 , pp. 1194-1200
    • Rossi, M.1    Arpinati, M.2    Rondelli, D.3    Anasetti, C.4
  • 50
    • 0032588116 scopus 로고    scopus 로고
    • Thymosin-alpha1 stimulates maturation of CD34+ stem cells into CD3+4+ cells in an in vitro thymic epithelia organ coculture model
    • Knutsen AP, Freeman JJ, Mueller KR, Roodman ST, Bouhasin JD. Thymosin-alpha1 stimulates maturation of CD34+ stem cells into CD3+4+ cells in an in vitro thymic epithelia organ coculture model. Int J Immunopharmacol. 1999;21:15-26.
    • (1999) Int J Immunopharmacol , vol.21 , pp. 15-26
    • Knutsen, A.P.1    Freeman, J.J.2    Mueller, K.R.3    Roodman, S.T.4    Bouhasin, J.D.5


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