메뉴 건너뛰기




Volumn 41, Issue 3, 2004, Pages 278-282

The roles of Smad2 and Smad3 in the development of chemically induced skin tumors in mice

Author keywords

Dimethylbenzanthracene; Keratinocytes; Mice; Papilloma; Squamous cell carcinoma; Transforming growth factor beta

Indexed keywords

DIMETHYLBENZ[A]ANTHRACENE; SMAD2 PROTEIN; SMAD3 PROTEIN;

EID: 2542450984     PISSN: 03009858     EISSN: None     Source Type: Journal    
DOI: 10.1354/vp.41-3-278     Document Type: Article
Times cited : (31)

References (21)
  • 3
    • 0030598681 scopus 로고    scopus 로고
    • TGFbetal inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice
    • Cui W, Fowlis DJ, Bryson S, Duffle E, Ireland H, Balmain A, Akhurst RJ: TGFbetal inhibits the formation of benign skin tumors, but enhances progression to invasive spindle carcinomas in transgenic mice. Cell 86:531-542, 1996
    • (1996) Cell , vol.86 , pp. 531-542
    • Cui, W.1    Fowlis, D.J.2    Bryson, S.3    Duffle, E.4    Ireland, H.5    Balmain, A.6    Akhurst, R.J.7
  • 4
    • 0031739638 scopus 로고    scopus 로고
    • Smad4 (DPC4)-a potent tumour suppressor?
    • Duff EK, Clarke AR: Smad4 (DPC4)-a potent tumour suppressor? Br J Cancer 78:1615-1619, 1998
    • (1998) Br J Cancer , vol.78 , pp. 1615-1619
    • Duff, E.K.1    Clarke, A.R.2
  • 8
    • 0035945639 scopus 로고    scopus 로고
    • Smads mediate signaling of the TGFbeta superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis
    • He W, Cao T, Smith DA, Myers TE, Wang XJ: Smads mediate signaling of the TGFbeta superfamily in normal keratinocytes but are lost during skin chemical carcinogenesis. Oncogene 20:471-483, 2001
    • (2001) Oncogene , vol.20 , pp. 471-483
    • He, W.1    Cao, T.2    Smith, D.A.3    Myers, T.E.4    Wang, X.J.5
  • 9
    • 0035694910 scopus 로고    scopus 로고
    • Smad regulation in TGF-beta signal transduction
    • Moustakas A, Souchelnytskyi S, Heldin CH: Smad regulation in TGF-beta signal transduction. J Cell Sci 114: 4359-4369, 2001
    • (2001) J Cell Sci , vol.114 , pp. 4359-4369
    • Moustakas, A.1    Souchelnytskyi, S.2    Heldin, C.H.3
  • 10
    • 0034901345 scopus 로고    scopus 로고
    • Defective transforming growth factor beta signaling pathway in head and neck squamous cell carcinoma as evidenced by the lack of expression of activated Smad2
    • Muro-Cacho CA, Rosario-Ortiz K, Livingston S, Munoz-Antonia T: Defective transforming growth factor beta signaling pathway in head and neck squamous cell carcinoma as evidenced by the lack of expression of activated Smad2. Clin Cancer Res 7:1618-1626, 2001
    • (2001) Clin Cancer Res , vol.7 , pp. 1618-1626
    • Muro-Cacho, C.A.1    Rosario-Ortiz, K.2    Livingston, S.3    Munoz-Antonia, T.4
  • 12
    • 0035907240 scopus 로고    scopus 로고
    • Identification of novel TGF-beta/Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach
    • Verrecchia F, Chu ML, Mauviel A: Identification of novel TGF-beta/Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach. J Biol Chem 276:17058-17062, 2001
    • (2001) J Biol Chem , vol.276 , pp. 17058-17062
    • Verrecchia, F.1    Chu, M.L.2    Mauviel, A.3
  • 13
    • 0035864356 scopus 로고    scopus 로고
    • Role of TGF-beta signaling in skin carcinogenesis
    • Wang XJ: Role of TGF-beta signaling in skin carcinogenesis. Microsc Res Tech 52:420-429, 2001
    • (2001) Microsc Res Tech , vol.52 , pp. 420-429
    • Wang, X.J.1
  • 14
    • 0034951680 scopus 로고    scopus 로고
    • Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on betal-integrin to promote normal liver development
    • Weinstein M, Monga SP, Liu Y, Brodie SG, Tang Y, Li C, Mishra L, Deng CX: Smad proteins and hepatocyte growth factor control parallel regulatory pathways that converge on betal-integrin to promote normal liver development. Mol Cell Biol 21:5122-5131, 2001.
    • (2001) Mol Cell Biol , vol.21 , pp. 5122-5131
    • Weinstein, M.1    Monga, S.P.2    Liu, Y.3    Brodie, S.G.4    Tang, Y.5    Li, C.6    Mishra, L.7    Deng, C.X.8
  • 15
    • 0034023371 scopus 로고    scopus 로고
    • Functions of mammalian Smad genes as revealed by targeted gene disruption in mice
    • Weinstein M, Yang X, Deng C: Functions of mammalian Smad genes as revealed by targeted gene disruption in mice. Cytokine Growth Factor Rev 11:49-58, 2000
    • (2000) Cytokine Growth Factor Rev , vol.11 , pp. 49-58
    • Weinstein, M.1    Yang, X.2    Deng, C.3
  • 16
    • 0032482751 scopus 로고    scopus 로고
    • Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2
    • Weinstein M, Yang X, Li C, Xu X, Gotay J, Deng CX: Failure of egg cylinder elongation and mesoderm induction in mouse embryos lacking the tumor suppressor smad2. Proc Natl Acad Sci USA 95:9378-9383, 1998
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9378-9383
    • Weinstein, M.1    Yang, X.2    Li, C.3    Xu, X.4    Gotay, J.5    Deng, C.X.6
  • 17
    • 0035162793 scopus 로고    scopus 로고
    • The transforming growth factor-beta signaling pathway in tumorigenesis
    • Wieser R: The transforming growth factor-beta signaling pathway in tumorigenesis. Curr Opin Oncol 13:70-77, 2001
    • (2001) Curr Opin Oncol , vol.13 , pp. 70-77
    • Wieser, R.1
  • 18
    • 0033104503 scopus 로고    scopus 로고
    • Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta
    • Yang X, Letterio JJ, Lechleider RJ, Chen L, Hayman R, Gu H, Roberts AB, Deng C: Targeted disruption of SMAD3 results in impaired mucosal immunity and diminished T cell responsiveness to TGF-beta. EMBO J 18:1280-1291, 1999
    • (1999) EMBO J , vol.18 , pp. 1280-1291
    • Yang, X.1    Letterio, J.J.2    Lechleider, R.J.3    Chen, L.4    Hayman, R.5    Gu, H.6    Roberts, A.B.7    Deng, C.8
  • 19
    • 0035914339 scopus 로고    scopus 로고
    • Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3
    • Yuan W, Varga J: Transforming growth factor-beta repression of matrix metalloproteinase-1 in dermal fibroblasts involves Smad3. J Biol Chem 276:38502-38510, 2001
    • (2001) J Biol Chem , vol.276 , pp. 38502-38510
    • Yuan, W.1    Varga, J.2
  • 21
    • 0032544448 scopus 로고    scopus 로고
    • Smad3 mutant mice develop metastatic colorectal cancer
    • Zhu Y, Richardson JA, Parada LF, Graff JM: Smad3 mutant mice develop metastatic colorectal cancer. Cell 94: 703-714, 1998
    • (1998) Cell , vol.94 , pp. 703-714
    • Zhu, Y.1    Richardson, J.A.2    Parada, L.F.3    Graff, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.