In the absence of type III receptor, the transforming growth factor (TGF)-β type II-B receptor requires the type I receptor to bind TGF-β2

Journal of Biological Chemistry

Volumn 279, Issue 21, 2004, Pages 22765-22772

  Del Re, Elisabetta ^a   Babitt, Jodie L ^a   Pirani, Alnoor ^a   Schneyer, Alan L ^a   Lin, Herbert Y ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; CRYSTAL STRUCTURE; CRYSTALLIZATION; GROWTH KINETICS; SIGNALING;

AFFINITY COMPLEXES; GROWTH FACTORS; LIGANDS;

BIOCHEMISTRY;

BETA GLYCAN; GLYCAN DERIVATIVE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 3; TRANSFORMING GROWTH FACTOR BETA2; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; CRYSTALLIZATION; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DOMAIN; RECEPTOR BINDING; SIGNAL TRANSDUCTION;

ACTIVIN RECEPTORS, TYPE I; ANIMALS; BLOTTING, WESTERN; CELL LINE; CELL MEMBRANE; CELL-FREE SYSTEM; CLONING, MOLECULAR; CRYSTALLOGRAPHY, X-RAY; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; GENES, REPORTER; GLYCOSYLATION; HUMANS; KINETICS; LIGANDS; LUCIFERASES; MICE; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; PHENOTYPE; PROTEIN BINDING; PROTEIN ISOFORMS; PROTEIN STRUCTURE, TERTIARY; PROTEOGLYCANS; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION;

EID: 2542425404     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M401350200     Document Type: Article

References (37)

1. Massague, J. (1990) Annu. Rev. Cell Biol. 6, 597-641
2. Shi, Y., and Massague, J. (2003) Cell 113, 685-700
3. Derynck, R., and Zhang, Y. E. (2003) Nature 425, 577-584
4. Roberts, A. B., and Sporn, M. B. (1990) Peptide Growth Factors and Their Receptors, Springer-Verlag, New York
5. Shull, M. M., Ormsby, I., Kier, A. B., Pawlowski, S., Diebold, R. J., Yin, M., Allen, R., Sidman, C., Proetzel, G., Calvin, D., Annunziata, N., and Doetschman, T. (1992) Nature 359, 693-699
6. Kulkarni, A. B., Huh, C. G., Becker, D., Geiser, A., Lyght, M., Flanders, K. C., Roberts, A. B., Sporn, M. B., Ward, J. M., and Karlsson, S. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 770-774
7. Kaartinen, V., Voncken, J. W., Shuler, C., Warburton, D., Bu, D., Heisterkamp, N., and Groffen, J. (1995) Nat. Genet. 11, 415-421
8. Sanford, L. P., Ormsby, I., de Gittenberger, G. A., Sariola, H., Frieman, R., Boivin, G. P., Cardell, E. L., and Doetschman, T. (1997) Development 124, 2659-2670
9. Piek, E., Heldin, C. H., and Ten Dijke, P. (1999) FASEB J. 13, 2105-2124
10. Lopez-Casillas, F., Cheifetz, S., Doody, J., Andres, J. L., Lane, W. S., and Massague, J. (1991) Cell 67, 785-795
11. Wang, X. F., Lin, H. Y., Ng-Eaton, E., Downward, J., Lodish, H. F., and Weinberg, R. A. (1991) Cell 67, 797-805
12. Lin, H. Y., Wang, X. F., Mg-Eaton, E., Weinberg, R. A., and Lodish, H. F. (1992) Cell 68, 775-785
13. ten Dijke, P., Ichijo, H., Franzen, P., Schulz, P., Saras, J., Toyoshima, H., Heldin, C. H., and Miyazono, K. (1993) Oncogene 8, 2879-2887
14. Suzuki, A., Shioda, N., Maeda, T., Tada, M., and Ueno, N. (1994) FEBS Lett. 335, 19-22
15. Hirai, R., and Fijita, T. (1996) Exp. Cell Res. 223, 135-141
16. Rotzer, D., Roth, M., Lutz, M., Lindemann, D., Sebald, W., and Knaus, P. (2001) EMBO J. 20, 480-490
17. Wrana, J. L., Attisano, L., Wieser, R., Ventura, F., and Massague, J. (1994) Nature 370, 341-347
18. Feng, X. H., and Derynck, R. (1997) EMBO J. 16, 3912-3923
19. Henis, Y. I., Moustakas, A., Lin, H. Y., and Lodish, H. F. (1994) J. Cell Biol. 126, 139-154
20. Gilboa, L., Wells, R. G., Lodish, H. F., and Henis, Y. I. (1998) Cell Biol. 140, 767-777
21. Daopin, S., Piez, K. A., Ogawa, Y., and Davies, D. R. (1992) Science 257, 369-373
22. Schlunegger, M. P., and Grutter, M. G. (1992) Nature 358, 430-444
23. Mittl, P. R., Priestle, J. P., Cox, D. A., McMaster, G., Cerletti, N., and Grutter, M. G. (1996) Protein Sci. 5, 1261-1271
24. Boesen, C. C., Radaev, S., Motyka, S. A., Patamawenu, A., and Sun, P. D. (2002) Structure 10, 913-919
25. Hart, P. J., Deep, S., Taylor, A. B., Shu, Z., Hinck, C. S., and Hinck, A. P. (2002) Nat. Struct. Biol. 9, 203-208
26. Kirsch, T., Sebald, W., and Dreyer, M. K. (2000) Nat. Struct. Biol. 7, 492-496
27. Greenwald, J., Groppe, J., Gray, P., Wiater, E., Kwiatkowski, W., Vale, W., and Choe, S. (2003) Mol. Cell 11, 605-617
28. Lopez-Casillas, F., Wrana, J. L., and Massague, J. (1993) Cell 73, 1435-1444
29. Stenvers, K. L., Tursky, M. L., Harder, K. W., Kountouri, N., Amatayakul-Chantler, S., Grail, D., Small, C., Weinberg, R. A., Sizeland, A. M., and Zhu, H. (2003) Mol. Cell. Biol. 23, 4371-4385
30. Rodriguez, C., Chen, F., Weinberg, R. A., and Lodish, H. F. (1995) J. Biol. Chem. 270, 15919-15922
31. Komesli, S., Vivien, D., and Dutartre, P. (1998) Eur. J. Biochem. 254, 505-513
32. Frolik, C. A., Wakefield, L. M., Smith, D. M., and Sporn, M. B. (1984) J. Biol. Chem. 259, 10995-11000
33. Dennler, S., Itoh, S., Vivien, D., ten Dijke, P., Huet, S., and Gauthier, J. M. (1998) EMBO J. 17, 3091-3100
34. Schneyer, A., Schoen, A., Quigg, A., and Sidis, Y. (2003) Endocrinology 144, 1671-1674
35. Docagne, F., Colloc'h, N., Bougueret, V., Page, M., Paput, J., Tripier, M., Dutartre, P., MacKenzie, E. T., Buisson, A., Komesli, S., and Vivien, D. (2001) J. Biol. Chem. 276, 46243-46250
36. Lin, H. Y., Moustakas, A., Knaus, P., Wells, R. G., Henis, Y. I., and Lodish, H. F. (1995) J. Biol. Chem. 270, 2747-2754
37. De Crescenzo, G., Pham, P. L., Durocher, Y., and O'Connor-McCourt, M. D. (2003) J. Mol. Biol. 328, 1173-1183