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Volumn 4, Issue 4, 2005, Pages 480-489

Natural retinoids inhibit proliferation and induce apoptosis in pancreatic cancer cells previously reported to be retinoid resistant

Author keywords

Apoptosis; Cancer cell proliferation; Differentiation; Pancreatic cancer; Retinoic acid

Indexed keywords

RETINOIC ACID; RETINOID;

EID: 25144449101     PISSN: 15384047     EISSN: 15558576     Source Type: Journal    
DOI: 10.4161/cbt.4.4.1701     Document Type: Article
Times cited : (21)

References (53)
  • 1
    • 0031047115 scopus 로고    scopus 로고
    • Molecular pathology of primary and metastatic ductal pancreatic lesions: Analysis of mutations and expression of the p53, mdm2, p21/waf-1 genes in sporadic and familial lesions
    • Ruggeri BA, Huang L, Berger D, Chang H, Klein-Szanto AJ, Goodrow T, Wood M, Obara T, Heath CW, Lynch H. Molecular pathology of primary and metastatic ductal pancreatic lesions: Analysis of mutations and expression of the p53, mdm2, p21/waf-1 genes in sporadic and familial lesions. Cancer 1997; 79:700-16.
    • (1997) Cancer , vol.79 , pp. 700-716
    • Ruggeri, B.A.1    Huang, L.2    Berger, D.3    Chang, H.4    Klein-Szanto, A.J.5    Goodrow, T.6    Wood, M.7    Obara, T.8    Heath, C.W.9    Lynch, H.10
  • 2
    • 25144512334 scopus 로고    scopus 로고
    • Molecular basis of pancreatic cancer: Strategies for genetic diagnosis and therapy
    • Johnson CD, Imrie CW, eds. London: Springer-Verlag
    • McCormick FC, Lemoine NR. Molecular basis of pancreatic cancer: Strategies for genetic diagnosis and therapy. In: Johnson CD, Imrie CW, eds. Pancreatic disease towards the year 2000. London: Springer-Verlag, 1999:267-80.
    • (1999) Pancreatic Disease Towards the Year 2000 , pp. 267-280
    • McCormick, F.C.1    Lemoine, N.R.2
  • 3
    • 0034041801 scopus 로고    scopus 로고
    • Pancreatic cancer: A review of emerging therapies
    • Rosenberg L. Pancreatic cancer: A review of emerging therapies. Drugs 2000; 59:1071-89.
    • (2000) Drugs , vol.59 , pp. 1071-1089
    • Rosenberg, L.1
  • 4
    • 0000147542 scopus 로고    scopus 로고
    • Recent advances in chemoprevention of cancer
    • Hong WK, Sporn MB. Recent advances in chemoprevention of cancer. Science 1997; 278:1073-7.
    • (1997) Science , vol.278 , pp. 1073-1077
    • Hong, W.K.1    Sporn, M.B.2
  • 5
    • 15644378537 scopus 로고    scopus 로고
    • The emerging role of retinoids and retinoic acid metabolism blocking agents in the treatment of cancer
    • Miller WH. The emerging role of retinoids and retinoic acid metabolism blocking agents in the treatment of cancer. Cancer 1998; 83:1471-82.
    • (1998) Cancer , vol.83 , pp. 1471-1482
    • Miller, W.H.1
  • 6
    • 0029798144 scopus 로고    scopus 로고
    • Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: A morphological and molecular analysis of four cell lines
    • Egawa N, Maillet B, VanDamme B, De Greve J, Kloppel G. Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: A morphological and molecular analysis of four cell lines. Verchows Arch 1996; 429:59-68.
    • (1996) Verchows Arch , vol.429 , pp. 59-68
    • Egawa, N.1    Maillet, B.2    Vandamme, B.3    De Greve, J.4    Kloppel, G.5
  • 8
    • 0029891788 scopus 로고    scopus 로고
    • Differential growth regulation by all-trans retinoic acid is determined by protein kinase Cα in human pancreatic carcinoma cells
    • Rosewicz S, Brembeck F, Kaiser A, Marschall ZV, Riecken EO. Differential growth regulation by all-trans retinoic acid is determined by protein kinase Cα in human pancreatic carcinoma cells. Endocrinology 1996; 137:3340-7.
    • (1996) Endocrinology , vol.137 , pp. 3340-3347
    • Rosewicz, S.1    Brembeck, F.2    Kaiser, A.3    Marschall, Z.V.4    Riecken, E.O.5
  • 10
    • 0030071519 scopus 로고    scopus 로고
    • All-trans retinoic acid inhibits growth of human pancreatic cancer cell lines
    • Bold RJ, Ishizuka J, Townsend CM, Thompson JC. All-trans retinoic acid inhibits growth of human pancreatic cancer cell lines. Pancreas 1996; 12:189-95.
    • (1996) Pancreas , vol.12 , pp. 189-195
    • Bold, R.J.1    Ishizuka, J.2    Townsend, C.M.3    Thompson, J.C.4
  • 11
    • 0030010937 scopus 로고    scopus 로고
    • Growth -inhibitory effects of vitamin D analogues and retinoids on human pancreatic cancer cells
    • Zugmaier G, Jager R, Grage B, Gottardis MM, Havemann K, Knabbe C. Growth -inhibitory effects of vitamin D analogues and retinoids on human pancreatic cancer cells. Br J Cancer 1996; 73:1341-6.
    • (1996) Br J Cancer , vol.73 , pp. 1341-1346
    • Zugmaier, G.1    Jager, R.2    Grage, B.3    Gottardis, M.M.4    Havemann, K.5    Knabbe, C.6
  • 12
    • 0347304616 scopus 로고    scopus 로고
    • Receptor dependent growth inhibition of human pancreatic cancer by 9-cis retinoic acid
    • Vickers SM, Sampson LK, Ying W, Phillips JO. Receptor dependent growth inhibition of human pancreatic cancer by 9-cis retinoic acid. J Gastrointest Surg 1997; 1:174-81.
    • (1997) J Gastrointest Surg , vol.1 , pp. 174-181
    • Vickers, S.M.1    Sampson, L.K.2    Ying, W.3    Phillips, J.O.4
  • 13
    • 0025075919 scopus 로고
    • Carbonic anhydrase gene expression in cell lines from human pancreatic adenocarcinoma
    • Frazier ML, Lilly BJ, Wu EF, Ota T, Hewett-Emmett D. Carbonic anhydrase gene expression in cell lines from human pancreatic adenocarcinoma. Pancreas 1990; 5:507-14.
    • (1990) Pancreas , vol.5 , pp. 507-514
    • Frazier, M.L.1    Lilly, B.J.2    Wu, E.F.3    Ota, T.4    Hewett-Emmett, D.5
  • 17
    • 0030763111 scopus 로고    scopus 로고
    • Arotinoid mofarotene (Ro 40-8757) upregulates p21 and p27 during growth inhibition of pancreatic cancer cell lines
    • Kawa S, Nikaido T, Aoki Y, Zhai Y, Kumagaya T, Furihata S, Fujii S, Kiyosawa K. Arotinoid mofarotene (Ro 40-8757) upregulates p21 and p27 during growth inhibition of pancreatic cancer cell lines. Int J Cancer 1997; 72:906-11.
    • (1997) Int J Cancer , vol.72 , pp. 906-911
    • Kawa, S.1    Nikaido, T.2    Aoki, Y.3    Zhai, Y.4    Kumagaya, T.5    Furihata, S.6    Fujii, S.7    Kiyosawa, K.8
  • 18
    • 0031610022 scopus 로고    scopus 로고
    • Effect of retinoic acid on morphological changes of human pancreatic cancer cells on collagen gels. A possible association with the metastatic potentials
    • Jimi S, Shono T, Tanaka M, Tanaka M, Kono A, Yamada Y, Shudo K, Kuwano M. Effect of retinoic acid on morphological changes of human pancreatic cancer cells on collagen gels. A possible association with the metastatic potentials. Oncol Res 1998; 10:7-14.
    • (1998) Oncol Res , vol.10 , pp. 7-14
    • Jimi, S.1    Shono, T.2    Tanaka, M.3    Tanaka, M.4    Kono, A.5    Yamada, Y.6    Shudo, K.7    Kuwano, M.8
  • 19
    • 0033551126 scopus 로고    scopus 로고
    • Optimization of treatment conditions for studying the anticancer effects of retinoids using pancreatic adenocarcinoma as a model
    • El-Metwally TH, Adrian TE. Optimization of treatment conditions for studying the anticancer effects of retinoids using pancreatic adenocarcinoma as a model. Biochem Biophys Res Comm 1999; 257:596-603.
    • (1999) Biochem Biophys Res Comm , vol.257 , pp. 596-603
    • El-Metwally, T.H.1    Adrian, T.E.2
  • 20
    • 0030625613 scopus 로고    scopus 로고
    • Apoptosis and the gastrointestinal system
    • Que F, Gores GJ. Apoptosis and the gastrointestinal system. Adv Pharmacology 1997; 41:409-28.
    • (1997) Adv Pharmacology , vol.41 , pp. 409-428
    • Que, F.1    Gores, G.J.2
  • 22
    • 0028329172 scopus 로고
    • Apoptosis, its significance in cancer and cancer therapy
    • Kerr JF, Winterford CM, Harmon BV. Apoptosis, its significance in cancer and cancer therapy. Cancer 1994; 73:2013-26.
    • (1994) Cancer , vol.73 , pp. 2013-2026
    • Kerr, J.F.1    Winterford, C.M.2    Harmon, B.V.3
  • 23
    • 0032998309 scopus 로고    scopus 로고
    • Overcoming Bcl-2- and p53-mediated resistance in prostate cancer
    • DiPaola RS, Aisner J. Overcoming Bcl-2- and p53-mediated resistance in prostate cancer. Semin Oncolg 1999; 26:112-6.
    • (1999) Semin Oncolg , vol.26 , pp. 112-116
    • DiPaola, R.S.1    Aisner, J.2
  • 25
    • 0029918819 scopus 로고    scopus 로고
    • Quantitation of DNA fragmentation in apoptosis
    • Ioannou YA, Chen FW. Quantitation of DNA fragmentation in apoptosis. Nucleic acid Res 1996; 245:992-3.
    • (1996) Nucleic Acid Res , vol.245 , pp. 992-993
    • Ioannou, Y.A.1    Chen, F.W.2
  • 27
    • 0034721852 scopus 로고    scopus 로고
    • Retinoic Acid-dependent transforming growth factor-β2-mediated induction of MUC4 mucin expression in human pancreatic tumor cells follows retinoic acid receptor-α signaling pathway
    • Choudhury A, Singh RK, Moniaux N, El-Metwally TH, Aubert JP, Batra SK. Retinoic Acid-dependent transforming growth factor-β2-mediated induction of MUC4 mucin expression in human pancreatic tumor cells follows retinoic acid receptor-α signaling pathway. J Biol Chem 2000; 275:33929-36.
    • (2000) J Biol Chem , vol.275 , pp. 33929-33936
    • Choudhury, A.1    Singh, R.K.2    Moniaux, N.3    El-Metwally, T.H.4    Aubert, J.P.5    Batra, S.K.6
  • 28
    • 0001744237 scopus 로고    scopus 로고
    • Retinoic acid normalized the increased gene transcription rate of TGFα and EGFR in head and neck cancer cell lines
    • Grandis JR, Zeng Q, Tweardy DJ. Retinoic acid normalized the increased gene transcription rate of TGFα and EGFR in head and neck cancer cell lines. Nature Med 1996; 2:237-40.
    • (1996) Nature Med , vol.2 , pp. 237-240
    • Grandis, J.R.1    Zeng, Q.2    Tweardy, D.J.3
  • 29
    • 0025759209 scopus 로고
    • Induction of TGFβ1 receptor expression and TGFβ1 protein production in retinoic acid-treated HL-60 cells: Possible TGFβ-mediated autocrine inhibition
    • Falk L, De Benedetti F, Lohrey N, Brichenall-Roberts MC, Ellingsworth LW, Faltynek CR, Ruscetti FW. Induction of TGFβ1 receptor expression and TGFβ1 protein production in retinoic acid-treated HL-60 cells: Possible TGFβ-mediated autocrine inhibition. Blood 1991; 77:1248-55.
    • (1991) Blood , vol.77 , pp. 1248-1255
    • Falk, L.1    De Benedetti, F.2    Lohrey, N.3    Brichenall-Roberts, M.C.4    Ellingsworth, L.W.5    Faltynek, C.R.6    Ruscetti, F.W.7
  • 30
    • 0344122907 scopus 로고    scopus 로고
    • Differentiation is a prerequisite for apoptosis in pancreatic cancer cells treated, with retinoids
    • El-Metwally TH, Pour PM, Kuszynski CA, Adrian TE. Differentiation is a prerequisite for apoptosis in pancreatic cancer cells treated, with retinoids. Pancreas 1998; 17:432.
    • (1998) Pancreas , vol.17 , pp. 432
    • El-Metwally, T.H.1    Pour, P.M.2    Kuszynski, C.A.3    Adrian, T.E.4
  • 31
    • 0023495596 scopus 로고
    • Ultrastructural differentiation and CEA expression of butyrate-treated human pancreatic carcinoma cells
    • El-Deriny SE, O'Brien MJ, Christensen TG, Kupchik HZ. Ultrastructural differentiation and CEA expression of butyrate-treated human pancreatic carcinoma cells. Pancreas 1987; 2:25-33.
    • (1987) Pancreas , vol.2 , pp. 25-33
    • El-Deriny, S.E.1    O'Brien, M.J.2    Christensen, T.G.3    Kupchik, H.Z.4
  • 34
    • 0031893331 scopus 로고    scopus 로고
    • Apoptosis, basic concepts and potential significance in human cancer
    • Staunton MJ, Gaffney EF. Apoptosis, basic concepts and potential significance in human cancer. Arch Pathol Lab Med 1998; 122:310-9.
    • (1998) Arch Pathol Lab Med , vol.122 , pp. 310-319
    • Staunton, M.J.1    Gaffney, E.F.2
  • 36
    • 0030612484 scopus 로고    scopus 로고
    • waf1 expression and growth inhibition by transforming factor β involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells
    • waf1 expression and growth inhibition by transforming factor β involve the tumor suppressor gene DPC4 in human pancreatic adenocarcinoma cells. Cancer Res 1997; 57:3929-34.
    • (1997) Cancer Res , vol.57 , pp. 3929-3934
    • Grau, A.M.1    Zhang, L.2    Wang, W.3    Ruan, S.4    Evans, D.B.5    Abbruzzese, J.L.6    Zhand, W.7    Chiao, P.J.8
  • 37
    • 0032568329 scopus 로고    scopus 로고
    • Stable reintroduction of wild type p53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells
    • Lang D, Miknyoczki SJ, Huang L, Ruggeri BA. Stable reintroduction of wild type p53 (MTmp53ts) causes the induction of apoptosis and neuroendocrine-like differentiation in human ductal pancreatic carcinoma cells. Oncogene 1998; 16:1593-602.
    • (1998) Oncogene , vol.16 , pp. 1593-1602
    • Lang, D.1    Miknyoczki, S.J.2    Huang, L.3    Ruggeri, B.A.4
  • 39
    • 0031034304 scopus 로고    scopus 로고
    • Cell-matrix and cell-cell interactions modulate apoptosis of bronchial epithelial cells
    • Lung Cell Mol Physiol
    • Aoshiba K, Rennard S, Spurzem J. Cell-matrix and cell-cell interactions modulate apoptosis of bronchial epithelial cells. Am J physiol 1997; 72:L28-37, (Lung Cell Mol Physiol).
    • (1997) Am J Physiol , vol.72
    • Aoshiba, K.1    Rennard, S.2    Spurzem, J.3
  • 40
    • 0031945458 scopus 로고    scopus 로고
    • Cell cycle regulation and apoptosis
    • King KL, Cidlowski JA. Cell cycle regulation and apoptosis. Annu Rev Physiol 1998; 60:601-17.
    • (1998) Annu Rev Physiol , vol.60 , pp. 601-617
    • King, K.L.1    Cidlowski, J.A.2
  • 41
    • 0030629944 scopus 로고    scopus 로고
    • Cell cycle checkpoints and apoptosis: Potential for improving radiation therapy
    • Muschel RJ, Mckenna WG, Bernhard EJ. Cell cycle checkpoints and apoptosis: Potential for improving radiation therapy. Vitamins and hormones 1997; 53:1-25.
    • (1997) Vitamins and Hormones , vol.53 , pp. 1-25
    • Muschel, R.J.1    Mckenna, W.G.2    Bernhard, E.J.3
  • 42
    • 0030944855 scopus 로고    scopus 로고
    • Effects of all-trans retinoic acid and 13-cis retinoic acid on breast cancer cell lines: Growth inhibition and apoptosis induction
    • Toma S, Isnardi L, Raffo P, Dastoli G, De-Francisci E, Riccardi L, Palumbo R, Bollag W. Effects of all-trans retinoic acid and 13-cis retinoic acid on breast cancer cell lines: Growth inhibition and apoptosis induction. Int J Cancer 1997; 70:619-27.
    • (1997) Int J Cancer , vol.70 , pp. 619-627
    • Toma, S.1    Isnardi, L.2    Raffo, P.3    Dastoli, G.4    De-Francisci, E.5    Riccardi, L.6    Palumbo, R.7    Bollag, W.8
  • 43
    • 0027724061 scopus 로고
    • Comparison of p53 protein expression and cellular localization in human and hamster pancreatic cancer cell lines
    • Mogaki M, Hirota M, Chaney WG, Pour PM. Comparison of p53 protein expression and cellular localization in human and hamster pancreatic cancer cell lines. Carcinogenesis 1993; 14:2587-94.
    • (1993) Carcinogenesis , vol.14 , pp. 2587-2594
    • Mogaki, M.1    Hirota, M.2    Chaney, W.G.3    Pour, P.M.4
  • 44
    • 0032127373 scopus 로고    scopus 로고
    • Mitochondrial membrane potential in the coordination of p53-independent proliferation and apoptosis pathways in human colonic carcinoma cells
    • Heerdt BG, Houston MA, Anthony GM, Augenlicht LH. Mitochondrial membrane potential in the coordination of p53-independent proliferation and apoptosis pathways in human colonic carcinoma cells. Cancer Res 1998; 58:2869-75.
    • (1998) Cancer Res , vol.58 , pp. 2869-2875
    • Heerdt, B.G.1    Houston, M.A.2    Anthony, G.M.3    Augenlicht, L.H.4
  • 45
    • 0033079597 scopus 로고    scopus 로고
    • Oncogenic alteration of metabolism
    • Dang CV, Semenza GL. Oncogenic alteration of metabolism. TIBS 1999:68-72.
    • (1999) TIBS , pp. 68-72
    • Dang, C.V.1    Semenza, G.L.2
  • 46
    • 0029017579 scopus 로고
    • Tissue transglutaminase; a candidate effector element of physiological cell death
    • Piacentini M. Tissue transglutaminase; A candidate effector element of physiological cell death. Curr Top Microbiol Immunol 1995; 200:163-75.
    • (1995) Curr Top Microbiol Immunol , vol.200 , pp. 163-175
    • Piacentini, M.1
  • 47
    • 0007607636 scopus 로고    scopus 로고
    • Retinoic acid induction of tissue transglutaminase promoter is mediated by a novel response element
    • Yan ZH, Noonan S, Nagy L, Davies PJ, Stein JP. Retinoic acid induction of tissue transglutaminase promoter is mediated by a novel response element. Mol Cell Endocrinol 1996; 120:203-12.
    • (1996) Mol Cell Endocrinol , vol.120 , pp. 203-212
    • Yan, Z.H.1    Noonan, S.2    Nagy, L.3    Davies, P.J.4    Stein, J.P.5
  • 48
    • 0028947023 scopus 로고
    • Evidence for the involvement of retinoic acid receptor RARα-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids
    • Zhang L-X, Mills KJ, Dawson MI, Collins SJ, Jetten AM. Evidence for the involvement of retinoic acid receptor RARα-dependent signaling pathway in the induction of tissue transglutaminase and apoptosis by retinoids. J Biol Chem 1995; 270:6022-9.
    • (1995) J Biol Chem , vol.270 , pp. 6022-6029
    • Zhang, L.-X.1    Mills, K.J.2    Dawson, M.I.3    Collins, S.J.4    Jetten, A.M.5
  • 49
    • 0030040841 scopus 로고    scopus 로고
    • Transglutaminase induced by epidermal growth factor negatively regulates the growth signal in primary cultured hepatocyte
    • Katoh S, Nakagawa N, Yano Y, Satoh K, Kohno H, Ohkubo Y. Transglutaminase induced by epidermal growth factor negatively regulates the growth signal in primary cultured hepatocyte. Biochem J 1996; 313:305-9.
    • (1996) Biochem J , vol.313 , pp. 305-309
    • Katoh, S.1    Nakagawa, N.2    Yano, Y.3    Satoh, K.4    Kohno, H.5    Ohkubo, Y.6
  • 50
    • 0027419881 scopus 로고
    • Requirement for transglutaminase in the activation of latent transforming growth factor-β in bovine endothelial cells
    • Kojima S, Nara K, Rifkin D. Requirement for transglutaminase in the activation of latent transforming growth factor-β in bovine endothelial cells. J Cell Biol 1993; 121:439-48.
    • (1993) J Cell Biol , vol.121 , pp. 439-448
    • Kojima, S.1    Nara, K.2    Rifkin, D.3
  • 51
    • 0027489430 scopus 로고
    • Transformation of NIH cells with ras oncogenes abrogates the retinoic acid induction of tissue transglutaminase
    • Kosa K, Meyers K, Luca LM. Transformation of NIH cells with ras oncogenes abrogates the retinoic acid induction of tissue transglutaminase. Biochem Biophys Res Comm 1993; 196:1025-33.
    • (1993) Biochem Biophys Res Comm , vol.196 , pp. 1025-1033
    • Kosa, K.1    Meyers, K.2    Luca, L.M.3
  • 52
    • 0023951530 scopus 로고
    • 2,3,7,8-tetrachlorodibenzo-p-dioxin and polycyclic aromatic hydrocarbons suppress retinoid-induced tissue transglutaminase in SCC-4 cultured human squamous carcinoma cells
    • Rubin AL, Rice RH. 2,3,7,8-tetrachlorodibenzo-p-dioxin and polycyclic aromatic hydrocarbons suppress retinoid-induced tissue transglutaminase in SCC-4 cultured human squamous carcinoma cells. Carcinogenesis 1988; 9:1067-70.
    • (1988) Carcinogenesis , vol.9 , pp. 1067-1070
    • Rubin, A.L.1    Rice, R.H.2
  • 53
    • 0141718360 scopus 로고    scopus 로고
    • Inhibitory effect of all-trans retinoic acid on human hepatocellular carcinoma cell proliferation
    • Piao YF, Shi Y, et al. Inhibitory effect of all-trans retinoic acid on human hepatocellular carcinoma cell proliferation. World J Gastroenterol 2003; 9:2117-20.
    • (2003) World J Gastroenterol , vol.9 , pp. 2117-2120
    • Piao, Y.F.1    Shi, Y.2


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