Growth-inhibitory effects of vitamin D analogues and retinoids on human pancreatic cancer cells

British Journal of Cancer

Volumn 73, Issue 11, 1996, Pages 1341-1346

  Zugmaier, G ^a   Jager R ^a   Grage, B ^b   Gottardis, M M ^c   Havemann, K ^a   Knabbe, C ^b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

^c Ligand Inc   (United States)

Author keywords

Pancreatic cancer; Reinoic acid; Retinoids; Vitamin D

Indexed keywords

ALITRETINOIN; RETINOIC ACID RECEPTOR; RETINOID; SEOCALCITOL; VITAMIN D DERIVATIVE; VITAMIN RECEPTOR;

ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PANCREAS ADENOCARCINOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

EID: 0030010937     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1038/bjc.1996.256     Document Type: Article

References (33)

1. BOLLAG W AND HOLDENER EE. (1992). Retinoids in cancer prevention and therapy. Ann. Oncol., 3, 513-526.
2. BOLLAG W AND PECK R. (1994). Cancer chemotherapy by combination of retinoids with cytocines and vitamin D analogs. Experimental and clinical results. Ann. Oncol. 5 (suppl. 9), 17-22.
3. COLSTON KW, MACCRAY AG, JAMES SY, BINDERUP L, CHANDERS S AND COOMBES C. (1992). EB1089: A new vitamin D analog that inhibits the growth of breast cancer cells in vivo and in vitro. Biochem. Pharmacol., 44, 2273-2280.
4. COLSTON KW. (1993). New concepts in hormone receptor action. Lancet, 342, 67-68.
5. CROSS HS, PAVELKA M, SLAVIK J AND PETERLIK M. (1992). Growth control of human colon cancer cells by vitamin D and calcium in vitro. J. Natl Cancer Inst., 84, 1355-1357.
6. DORE BT, USKOOBOVIC MR AND MOOMPARLER RL. (1993). Interaction of retinoic acid and vitamin D3 analogues on HL-60 myeloid leukemic cells. Leukaemic Res., 17, 749-757.
7. ELIASON JF, KAUFMANN F, TANAKA T AND TSUKAGUCHI T. (1993). Anti-proliferative effects of the arotinoid Ro 40-8557 on human cancer cell lines in vitro. Br. J. Cancer, 67, 1293-1298.
8. EVANS RM. (1988). The steroid and thyroid receptor superfamily. Science, 240, 889-895.
9. FORMELLI F AND CLERIS L. (1993). Synthetic retinoid fenretinidine is effective against a human ovarian carcinoma xenograft and potentiates cisplatin activity. Cancer Res., 53, 5374-5376.
10. GERADTS J, CHEN J-Y, RUSSELL EK, YANKASKAS JR, NIEVES L AND MINNA JD. (1993). Human lung cancer cell lines exhibit resistance to retinoic acid treatment. Cell Growth Different., 4, 799-809.
11. GUDAS LJ. (1992). Retinoids, retinoid-responsive genes, cell-differentiation, and cancer. Cell Growth Different., 3, 655-662.
12. HARANT H, KORSCHINEK I, KRUPIZA G, FAZENY B, DITTRICH C AND GRUNT TW. (1993). Retinoic acid receptors in retinoid responsive ovarian cancer cell lines detected by polymerase chain reaction following reverse transcription. Br. J. Cancer, 68, 530-536.
13. JEEKEL J. (1994). Surgery of pancreatic cancer. Ann. Oncol., 5 (suppl. 3), S73-S74.
14. KELLY DM AND BENJAMIN IS. (1995). Pancreatic carcinoma. Ann. Oncol., 6, 19-25.
15. LOTAN R, XU XC, LIPPMAN S, RO JY, LEE JS AND HONG WK. (1995). Suppression of retinoic acid receptor-β in premalignant oral lesions and its up-regulation by isoretinoin. N. Engl. J. Med., 332, 1405-1410.
16. LUTZKY J, VUJICIC M, BINDERUP L AND BHALLA K. (1994). Vitamin D analogues and retinoids exhibit additive cytotoxicity to human myeloma cell lines. Proc. AARC, 35, 2434.
17. MANIATIS T, FRITSCH EF AND SAMBROOK J. (1989). Molecular Cloning. Cold Spring Harbor: New York.
18. MILLER GJ, STAPLETON GE, FERRARA JA, LUCIA MS, PFISTER S, HEDLUND TE AND UPADHYA P. (1992). The human prostatic carcinoma cell line LNCaP expresses biologically active specific receptors for 1,25-dihydroxyvitamin D3. Cancer Res., 52, 512-520.
19. PEEHL DM, SKORONOWSKI RJ, LEUNG GK, WONG ST, STAMEY TA AND FELDMAN D. (1994). Anti-proliferative effects of 1,25-dihydroxyvitamin D3 on primary cultures of human prostatic cells. Cancer Res., 54, 805-810.
20. PFEFFER U, FECAROTTA E AND VIDALI G. (1995). Efficient one-tube RT-PTCR amplification of rare transcripts using short sequence-specific reverse transcription primers. BioTechniques, 18, 204-206.
21. PIENTA KJ, NGUYEN NM AND LEHR JE. (1993). Treatment of prostate cancer in the rat with the synthetic retinoid fenretinide. Cancer Res., 53, 224-226.
22. REICHEL R, KOEFFLER P AND NORMAN A. (1989). The role of vitamin D endocrine system in health and disease. N. Engl. J. Med., 320, 980-991.
23. ROMAN SD, CLARKE C, HALL RE, ALEXANDER IE AND SUTHERLAND RL. (1992). Expression and regulation of retinoic acid receptors in human breast cancer cells. Cancer Res., 52, 2236-2242.
24. SCOTT-MACKIE P, HICKISH T, MORTIMER P, SLOOANE J AND CUNNINGHAM D. (1993). Calcipotriol and regression in T-cell lymphoma of the skin. Lancet, 342, 172.
25. SHABAHANG M, BURAS RR, DAVOODI F, SHUMAKER LM, NAUTA RJ AND EVANS SRT. (1993). 1,25-dihydroxyvitamin D3 receptor as a marker of human colon carcinoma cell line differentiation and growth inhibition. Cancer Res., 53, 3712-3718.
26. SHABAHANG M, BURAS RR, DAVOODI F, SHUMAKER LM, NAUTA RJ, USKOKOVIC MR AND EVANS SRT. (1994). Growth inhibition of HT-29 human colon cancer cells by analogs of 1,25-dihydroxyvitamin D3. Cancer Res., 54, 4057-4064.
27. SPORN MB AND ROBERTS A. (1983). Role of retinoids in differentiation and carcinogenesis. Cancer Res. 43, 3034-3040.
28. SUGGS SV, WALLACE RB, HIROSE T. KAWASHIMA EH AND ITAKURA K. (1981). Use of synthetic oligonucleotides as hybridization probes: isolation of cloned cDNA sequences for human β-2-microglobulin. Proc. Natl Acad. Sci. USA, 78, 6613-6617.
29. SWISSHELM K, RYAN K, LEE X, TSOU HC, PEACOCKE M AND SAGER R. (1994). Down regulation of retinoic acid receptor β in mammary carcinoma cell lines and its up-regulation in senescing normal mammary epithelial cells. Cell Growth Different., 5, 133-141.
30. TEELMAN K, TSUKACHUGI T, KLAUS M AND ELIASON JF. (1993). Comparison of the therapeutic effects of a new arotinoid, Ro 40-8557 and all-trans and 13-cis-retinoic acids on rat breast cancer. Cancer Res., 53, 2319-2325.
31. VAN DER LEEDE BM, VAN DER BRINK CE AND VAN DER SAAG PT. (1993). Retinoic acid receptor and retinoid X receptor expression in retinoic acid resistant human tumour cell lines. Mol. Carcinogen., 8, 112-122.
32. WAGENER JT, PUNT CJA AND WILKE H. (1994). Current status and future directions in the perioperative treatment of pancreatic cancer. Ann. Oncol., 5 (suppl. 3), S87-S90.
33. XU X, RO JY, LEE JS, SHIN DM, HONG WK AND LOTAN R. (1994). Differential expression of nuclear retinoid receptors on normal premalignant and malignant head and neck tissues. Cancer Res., 54, 3580-3587.