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Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 21, 2005, Pages 4656-4661

Exploring the connection unit in the HDAC inhibitor pharmacophore model: Novel uracil-based hydroxamates

(8) Mai, Antonello a Massa, Silvio b Rotili, Dante a Pezzi, Riccardo a Bottoni, Patrizia c Scatena, Roberto c Meraner, Joachim d Brosch, Gerald d

a SAPIENZA UNIVERSITY OF ROME (Italy)

b UNIVERSITY OF SIENA (Italy)

c CATHOLIC UNIVERSITY (Italy)

d INNSBRUCK MEDICAL UNIVERSITY (Austria)

Author keywords

[No Author keywords available]

Indexed keywords

HISTONE DEACETYLASE INHIBITOR; HYDROXAMIC ACID DERIVATIVE; N HYDROXY 6 (3,4 DIHYDRO 4 OXO 6 BENZYL 2 PYRIMIDINYLTHIO)HEXANAMIDE; N HYDROXY 6 (3,4 DIHYDRO 4 OXO 6 PHENYL 2 PYRIMIDINYLTHIO)HEXANAMIDE; TRICHOSTATIN A; UNCLASSIFIED DRUG; URACIL DERIVATIVE; VORINOSTAT;

ACETYLATION; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOLOGY; DRUG DESIGN; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; MOUSE; NONHUMAN; PHARMACOPHORE;

ACETYLATION; ANIMALS; ANTINEOPLASTIC AGENTS; CELL DIFFERENTIATION; CELL PROLIFERATION; DRUG DESIGN; HISTONE DEACETYLASES; HISTONES; HL-60 CELLS; HUMANS; HYDROXAMIC ACIDS; MICE; MODELS, MOLECULAR; NIH 3T3 CELLS; URACIL;

EID: 25144444434 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2005.07.081 Document Type: Article

Times cited : (48)

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