CaMKIIδ overexpression in hypertrophy and heart failure: Cellular consequences for excitation-contraction coupling

Brazilian Journal of Medical and Biological Research

Volumn 38, Issue 9, 2005, Pages 1293-1302

  Maier, L S ^a  

^a UNIVERSITY MEDICAL CENTER GÖTTINGEN   (Germany)

Author keywords

Calcium; Calmodulin; CaM kinase; Excitation contraction coupling; Heart

Indexed keywords

CALCIUM CHANNEL L TYPE; CALCIUM ION; PHOSPHOLAMBAN; PROTEIN KINASE (CALCIUM,CALMODULIN) II; RYANODINE RECEPTOR; CALMODULIN DEPENDENT PROTEIN KINASE II; CALMODULIN-DEPENDENT PROTEIN KINASE II; ISOENZYME; PROTEIN KINASE (CALCIUM,CALMODULIN);

ACIDOSIS; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL PH; CORRELATION ANALYSIS; DISEASE SEVERITY; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME STRUCTURE; EXCITATION CONTRACTION COUPLING; GENE OVEREXPRESSION; HEART ARRHYTHMIA; HEART EJECTION FRACTION; HEART FAILURE; HEART HYPERTROPHY; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REVIEW; SARCOPLASMIC RETICULUM; ANIMAL; CARDIOMEGALY; CONGESTIVE HEART FAILURE; ENZYMOLOGY; GENETICS; HEART CONTRACTION; HUMAN; METABOLISM;

ANIMALIA;

ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CARDIOMEGALY; HEART FAILURE, CONGESTIVE; HUMANS; ISOENZYMES; MYOCARDIAL CONTRACTION; SARCOPLASMIC RETICULUM;

EID: 24744447090     PISSN: 0100879X     EISSN: 1414431X     Source Type: Journal    
DOI: 10.1590/S0100-879X2005000900002     Document Type: Review

References (58)

1. Braun AP & Schulman H (1995). The multifunctional calcium/calmodulin-dependent protein kinase: from form to function. Annual Review of Physiology, 57: 417-445.
2. Maier LS & Bers DM (2002). Calcium, calmodulin, and calcium-calmodulin kinase II: heartbeat to heartbeat and beyond. Journal of Molecular and Cellular Cardiology, 34: 919-939.
3. 2+/CaM-dependent kinases: From activation to function. Annual Review of Pharmacology and Toxicology, 41: 471-505.
4. 2+/calmodulin-dependent protein kinase II in cardiac hypertrophy and heart failure. Cardiovascular Research, 63: 476-486.
5. Meyer T, Hanson PI, Stryer L et al. (1992). Calmodulin trapping by calcium-calmodulin-dependent protein kinase. Science, 256: 1199-1202.
6. Miller SB & Kennedy MB (1986). Regulation of brain type II Ca/calmodulin-dependent protein kinase by autophosphorylation: A Catrigger molecular switch. Cell, 44: 861-870.
7. Lai Y, Nairn AC & Greengard P (1986). Autophosphorylation reversibly regulates the Ca/calmodulin-dependent protein kinase II. Proceedings of the National Academy of Sciences, USA, 83: 4253-4257.
8. Lou LL, Lloyd SJ & Schulman H (1986). Activation of the multifunctional Ca/calmodulin-dependent protein kinase by autophosphorylation: ATP modulates production of an autonomous enzyme. Proceedings of the National Academy of Sciences, USA, 83: 9497-9501.
9. Schworer CM, Colbran RJ & Soderling TR (1986). Reversible generation of a Ca-independent form of Ca (calmodulin)-dependent protein kinase II by an autophosphorylation mechanism. Journal of Biological Chemistry, 261: 8581-8584.
10. Li L, Satoh H, Ginsburg KS et al. (1997). The effect of Ca-calmodulin-dependent protein kinase II on cardiac excitation-contraction coupling in ferret ventricular myocytes. Journal of Physiology, 501: 17-32.
11. ++/calmodulin-dependent protein kinase, decreases early afterdepolarizations in rabbit heart. Journal of Pharmacology and Experimental Therapeutics, 287: 996-1006.
12. Ishida A, Kameshita I, Okuno S et al. (1995). A novel specific and potent inhibitor of calmodulin-dependent protein kinase II. Biochemical and Biophysical Research Communications, 212: 806-812.
13. 2+ current: a cellular mechanism for long Q-T arrhythmias. American Journal of Physiology, 276: H2168-H2178.
14. Bers DM (2002). Cardiac excitation-contraction coupling. Nature, 415: 198-205.
15. Witcher DR, Kovacs RJ, Schulman H et al. (1991). Unique phosphorylation site on the cardiac ryanodine receptor regulates calcium channel activity. Journal of Biological Chemistry, 266: 11144-11152.
16. Hain J, Onoue H, Mayrleitner M et al. (1995). Phosphorylation modulates the function of the calcium release channel of sarcoplasmic reticulum from cardiac muscle. Journal of Biological Chemistry, 270: 2074-2081.
17. Davis BA, Schwartz A, Samaha FJ et al. (1983). Regulation of cardiac sarcoplasmic reticulum calcium transport by calcium-calmodulin-dependent phosphorylation. Journal of Biological Chemistry, 258: 13587-13591.
18. Simmerman HKB, Collins JH, Theibert JL et al. (1986). Sequence analysis of PLB: Identification of phosphorylation sites and two major structural domains. Journal of Biological Chemistry, 261: 13333-13341.
19. Lee KS (1987). Potentiation of the calcium-channel currents of internally perfused mammalian heart cells by repetitive depolarization. Proceedings of the National Academy of Sciences, USA, 84: 3941-3945.
20. Hryshko LV & Bers DM (1990). Ca current facilitation during post-rest recovery depends on Ca entry. American Journal of Physiology, 259: H951-H961.
21. Yuan W & Bers DM (1994). Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin dependent protein kinase. American Journal of Physiology, 267: H982-H993.
22. Anderson ME, Braun AP, Schulman H et al. (1994). Multifunctional Ca/calmodulin-dependent protein kinase mediates Ca-induced enhancement of the L-type Ca current in rabbit ventricular myocytes. Circulation Research, 75: 854-861.
23. Xiao RP, Cheng H, Lederer WJ et al. (1994). Dual regulation of Ca/calmodulin kinase II activity by membrane voltage and by calcium influx. Proceedings of the National Academy of Sciences, USA, 91: 9659-9663.
24. Dzhura I, Wu Y, Colbran RJ et al. (2000). Calmodulin kinase determines calcium-dependent facilitation of L-type calcium channels. Nature Cell Biology, 2: 173-177.
25. Lokuta AJ, Rogers TB, Lederer WJ et al. (1997). Modulation of cardiac ryanodine receptors of swine and rabbit by a phosphorylation-dephosphorylation mechanism. Journal of Physiology, 487: 609-622.
26. duBell WH, Lederer WJ & Rogers TB (1996). Dynamic modulation of excitation-contraction coupling by protein phosphatase in rat ventricular myocytes. Journal of Physiology, 493: 793-800.
27. Wu Y, Colbran RJ & Anderson ME (2001). Calmodulin kinase is a molecular switch for cardiac excitation-contraction coupling. Proceedings of the National Academy of Sciences, USA, 98: 2877-2881.
28. Zhang T, Maier LS, Dalton ND et al. (2003). The δC isoform of CaMKII is activated in cardiac hypertrophy and induces dilated cardiomyopathy and heart failure. Circulation Research, 92: 912-919.
29. 2+ release. Circulation Research, 92: 904-911.
30. Currie S, Loughrey CM, Craig MA et al. (2004). Calcium/calmodulin-dependent protein kinase IIδ associates with the ryanodine receptor complex and regulates channel function in rabbit heart. Biochemical Journal, 377: 357-366.
31. 2+/calmodulin-dependent protein kinase II phosphorylation regulates the cardiac ryanodine receptor. Circulation Research, 94: e61-e70.
32. Brittsan AG & Kranias EG (2000). Phospholamban and cardiac contractile function. Journal of Molecular and Cellular Cardiology, 32: 2131-2139.
33. Bassani RA, Mattiazzi A & Bers DM (1995). CaMKII is responsible for activity-dependent acceleration of relaxation in rat ventricular myocytes. American Journal of Physiology, 268: H703-H712.
34. Hagemann D, Kuschel M, Kuramochi T et al. (2000). Frequency-encoding Thr17 phospholamban phosphorylation is independent of Ser16 phosphorylation in cardiac myocytes. Journal of Biological Chemistry, 275: 22532-22536.
35. Schouten VJ (1990). Interval dependence of force and twitch duration in rat heart explained by Ca pump inactivation in sarcoplasmic reticulum. Journal of Physiology, 431: 427-444.
36. DeSantiago J, Maier LS & Bers DM (2002). Frequency-dependent acceleration of relaxation in the heart depends on CaMKII, but not phospholamban. Journal of Molecular and Cellular Cardiology, 34: 975-984.
37. Bers DM (2001). Excitation-Contraction Coupling and Cardiac Contractile Force. 2nd edn. Kluwer Academic Publishers, Dordrecht, The Netherlands.
38. 2+ uptake and contractile recovery during intracellular acidosis. American Journal of Physiology, 283: H193-H203.
39. Ca and SR function during acidosis in rat ventricular myocytes. Pflügers Archiv, 442: 353-361.
40. Vittone L, Mundiña-Wailenmann C, Said M et al. (1998). Mechanisms involved in the acidosis enhancement of the isoproterenol-induced phosphorylation of phospholamban in the intact heart. Journal of Biological Chemistry, 273: 9804-9811.
41. DeSantiago J, Maier LS & Bers DM (2004). Phospholamban is required for CaMKII-dependent recovery of Ca transients and SR Ca reuptake during acidosis in cardiac myocytes. Journal of Molecular and Cellular Cardiology, 36: 67-74.
42. Sag CM, DeSantiago J, Bers DM et al. (2004). Recovery of Ca transients, SR Ca reuptake and shortening during acidosis requires the CaMKII/PLB signaling pathway but is impaired in heart failure. European Heart Journal, 25 (Suppl): 179 (Abstract).
43. Wu Y, Temple J, Zhang R et al. (2002). Calmodulin kinase II and arrhythmias in a mouse model of cardiac hypertrophy. Circulation, 106: 1288-1293.
44. Wagner S, Rasenack ECL, Jacobshagen C et al. (2004). Ca/calmodulin-dependent protein kinase II (CaMKII) reduces the availability of cardiac voltage-gated Na channels. Circulation, 110 (Suppl III): 61 (Abstract).
45. 2+ /calmodulin-dependent protein kinases II in human atrial myocytes. Circulation Research, 85: 810-819.
46. Gruver CL, DeMayo F, Goldstein MA et al. (1993). Targeted developmental overexpression of calmodulin induced proliferative and hypertrophic growth of cardiomyocytes in transgenic mice. Endocrinology, 133: 376-388.
47. Colomer JM & Means AR (2000). Chronic elevation of calmodulin in the ventricles of transgenic mice increases the autonomous activity of calmodulin-dependent protein kinase II, which regulates atrial natriuretic factor gene expression. Molecular Endocrinology, 14: 1125-1136.
48. 2+/calmodulin-dependent kinase II and Galcineurin play critical roles in endothelin-1-induced cardiomyocyte hypertrophy. Journal of Biological Chemistry, 275: 15239-15245.
49. Passier R, Zeng H, Frey N et al. (2000). CaM kinase signaling induces cardiac hypertrophy and activates the MEF2 transcription factor in vivo. Journal of Clinical Investigation, 105: 1395-1406.
50. McKinsey TA, Zhang CL & Olson EN (2002). MEF2: a calcium-dependent regulator of cell division, differentiation and death. Trends in Biochemical Sciences, 27: 40-47.
51. McKinsey TA, Zhang CL, Lu J et al. (2000). Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature, 408: 106-111.
52. Wu X, Bossuyt J, Zhang T et al. (2004). Excitation-transcription coupling in adult myocytes: Local InsP3-dependent perinuclear signaling activates HDAC nuclear export. Circulation, 110: II-285 (Abstract).
53. Bare DJ, Bers DM & Mignery GA (2004). InsP3 receptors in ventricular myocytes are primarily in the nuclear envelope, associate with CaMKIIδ, and are phosphorylation targets. Circulation, 110: II-159 (Abstract).
54. 2+ /calmodulin kinase signaling pathway. Circulation Research, 95: 798-806.
55. 2+/calmodulin kinase II. Jounal of Clinical Investigation, 111: 617-625.
56. Marx SO, Reiken S, Hisamatsu Y et al. (2000). PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts. Cell, 101: 365-376.
57. B isoform of Ca/calmodulin-dependent protein kinase II regulates atrial natriuretic factor gene expression in ventricular myocytes. Journal of Biological Chemistry, 272: 31203-31208.
58. 2+ /calmodulin-dependent protein kinase II induces hypertrophy and dilated cardiomyopathy associated with increased protein phosphatase 2A activity. Journal of Biological Chemistry, 277: 1261-1267.