Sequence optimization and designability of enzyme active sites

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 34, 2005, Pages 12035-12040

  Chakrabarti, Raj ^a,b   Klibanov, Alexander M ^b   Friesner, Richard A ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEOSIDE;

ARTICLE; BINDING AFFINITY; CALCULATION; CATALYSIS; CHEMICAL REACTION; COMPLEX FORMATION; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SUBSTRATE; HYDROGEN BOND; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN STABILITY; SEQUENCE HOMOLOGY;

ALGORITHMS; AMINO ACID SEQUENCE; BINDING SITES; CATALYSIS; ENZYMES; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN ENGINEERING; SUBSTRATE SPECIFICITY;

EID: 24744432713     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0505397102     Document Type: Article

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