Recent advances using rodent models for predicting human allergenicity

Toxicology and Applied Pharmacology

Volumn 207, Issue 2 SUPPL., 2005, Pages 157-160

  Knippels, Léon M J ^a   Penninks, André H ^a  

^a TNO   (Netherlands)

Author keywords

Allergenicity; Animal models; Food allergy

Indexed keywords

ALBUMINOID; EGG WHITE; FOOD ALLERGEN; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; OVALBUMIN; VEGETABLE PROTEIN;

ALLERGENICITY; CONFERENCE PAPER; DNA MODIFICATION; EXPERIMENTAL MODEL; FOOD ALLERGY; FOOD INDUSTRY; GENETIC ENGINEERING; GENETICALLY MODIFIED FOOD; MILK; MOUSE STRAIN; NONHUMAN; PLANT GENETICS; PROVOCATION TEST; RAT STRAIN; SENSITIZATION; VALIDATION PROCESS; WORLD HEALTH ORGANIZATION;

ANIMALIA; RODENTIA;

EID: 24644472026     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.01.031     Document Type: Conference Paper

References (11)

1. R.J. Dearman, and I. Kimber Determination of protein allergenicity: studies in mice Toxicol. Lett. 120 2001 181 186
2. R.J. Dearman, H. Caddick, D.A. Basketter, and I. Kimber Divergent antibody responses induced in mice by systemic exposure to proteins: a comparison of ovalbumin with bovine serum albumin Food Chem. Toxicol. 38 2000 351 360
3. R.J. Dearman, S. Stone, H.T. Caddick, D.A. Basketter, and I. Kimber Evaluation of protein allergenic potential in mice: dose-response analyses Clin. Exp. Allergy 33 2003 1586 1594
4. FAO/WHO Evaluation of allergenicity of genetically modified foods Report of a Joint FAO/WHO Expert Consultation on Allergenicity of Foods derived from Biotechnology; 22-25 January 2001; Rome, Italy 2001
5. I. Kimber, S. Stone, and R.J. Dearman Assessment of the inherent allergenic potential of proteins in mice Environ. Health Perspect. 111 2003 227 231
6. L.M.J. Knippels, and A.H. Penninks Assessment of the allergic potential of food protein extracts and proteins on oral application using the Brown Norway rat model Environ. Health Perspect. 111 2003 233 238
7. L.M.J. Knippels, A.H. Penninks, S. Spanhaak, and G.F. Houben Oral sensitization to food proteins: a Brown Norway rat model Clin. Exp. Allergy 28 1998 368 375
8. L.M.J. Knippels, A.H. Penninks, J.J. Smit, and G.F. Houben Immune-mediated effects upon oral challenge of ovalbumin sensitized Brown Norway rats; further characterization of a rat food allergy model Toxicol. Appl. Pharmacol. 156 1999 161 169
9. L.M.J. Knippels, A.A. Felius, H.P.M. van der Kleij, A.H. Penninks, S.J. Koppelman, and G.F. Houben Comparison of antibody responses to hen's egg and cow's milk-proteins in orally sensitized rats and human patients Allergy 55 2000 251 258
10. D.D. Metcalfe, J.D. Astwood, R. Townsend, H.A. Sampson, S.L. Taylor, and R.L. Fuchs Assessment of the allergenic potential of foods from genetically engineered crop plants Crit. Rev. Food Sci. Nutr. 36(S) 1996 165 186
11. A.H. Penninks, and L.M.J. Knippels Determination of protein allergenicity: studies in rats Toxicol. Lett. 120 2001 171 180