Phosphorylated FADD induces NF-κB, perturbs cell cycle, and is associated with poor outcome in lung adenocarcinomas

Proceedings of the National Academy of Sciences of the United States of America

Volumn 102, Issue 35, 2005, Pages 12507-12512

  Chen, Guoan ^a   Bhojani, Mahaveer S ^a,b   Heaford, Andrew C ^a   Chang, Daniel C ^b   Laxman, Bharathi ^b   Thomas, Dafydd G ^a   Griffin, Laura B ^b   Yu, James ^b   Coppola, Julia M ^b   Giordano, Thomas J ^a   Lin, Lin ^a   Adams, David ^b   Orringer, Mark B ^a   Ross, Brian D ^a   Beer, David G ^a,b   Rehemtulla, Alnawaz ^a,b  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

Lung cancer; Proliferation; Survival

Indexed keywords

BIOLOGICAL MARKER; CYCLIN B1; CYCLIN D1; FAS ASSOCIATED DEATH DOMAIN PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA;

ARTICLE; CELL CULTURE; CELL CYCLE; CELL CYCLE G2 PHASE; CELL PROLIFERATION; CONTROLLED STUDY; DNA MICROARRAY; FADD GENE; GENE; GENE AMPLIFICATION; GENE EXPRESSION; GENE MUTATION; GENE SEQUENCE; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG ADENOCARCINOMA; LUNG CANCER; LUNG CARCINOGENESIS; METASTASIS; PRIORITY JOURNAL; PROGNOSIS; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SURVIVAL RATE; TISSUE MICROARRAY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADENOCARCINOMA; APOPTOSIS; CELL CYCLE; CELL NUCLEUS; CELL PROLIFERATION; DNA, NEOPLASM; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; GENE AMPLIFICATION; GENE EXPRESSION; HUMANS; JURKAT CELLS; LUNG NEOPLASMS; MUTATION; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PHOSPHORYLATION; PROGNOSIS; RNA, MESSENGER; RNA, NEOPLASM; RNA, SMALL INTERFERING; SERINE;

EID: 24644442745     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0500397102     Document Type: Article

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