-
2
-
-
0032414886
-
Regulation of caspase activation in apoptosis: Implications for transformation and drug resistance
-
Ed. Martin Glynes. Kluwer Academic Publishers
-
Slee E and Martin S: Regulation of caspase activation in apoptosis: implications for transformation and drug resistance. In: Multiple Drug Resistance in Cancer 2. Molecular, Cellular and Cancer Aspects. Ed. Martin Glynes. Kluwer Academic Publishers pp 309-321, 1998.
-
(1998)
Multiple Drug Resistance in Cancer 2. Molecular, Cellular and Cancer Aspects
, pp. 309-321
-
-
Slee, E.1
Martin, S.2
-
3
-
-
0033709907
-
Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation
-
Zheng T, Huno S, Kuida K, Momoi T, Srinivasan A, Nicholson D, Lazebnik Y and Flavell R: Deficiency in caspase-9 or caspase-3 induces compensatory caspase activation. Nature Medicine 6(11): 1241-7, 2000.
-
(2000)
Nature Medicine
, vol.6
, Issue.11
, pp. 1241-1247
-
-
Zheng, T.1
Huno, S.2
Kuida, K.3
Momoi, T.4
Srinivasan, A.5
Nicholson, D.6
Lazebnik, Y.7
Flavell, R.8
-
4
-
-
0035896406
-
A docking model of key components of the DISC complex: Death domain superfamily interactions redefined
-
Weber C and Vincenz C: A docking model of key components of the DISC complex: death domain superfamily interactions redefined. FEBS Letters 492: 171-176, 2001.
-
(2001)
FEBS Letters
, vol.492
, pp. 171-176
-
-
Weber, C.1
Vincenz, C.2
-
5
-
-
0033908043
-
The most unkindest cut of all: On the multiple roles of mammalian caspases
-
Fadeel B, Orrenius S and Zhivotovsky B: The most unkindest cut of all: on the multiple roles of mammalian caspases. Leukemia 14(8): 1514-25, 2000.
-
(2000)
Leukemia
, vol.14
, Issue.8
, pp. 1514-1525
-
-
Fadeel, B.1
Orrenius, S.2
Zhivotovsky, B.3
-
6
-
-
0033429233
-
Death by design: Mechanism and control of apoptosis
-
Song Z and Steller H: Death by design: mechanism and control of apoptosis. Trends Cell Biol 9(12): M49-52, 1999.
-
(1999)
Trends Cell Biol
, vol.9
, Issue.12
-
-
Song, Z.1
Steller, H.2
-
7
-
-
0032988573
-
Synthesis of procaspases-3 and -7 during apoptosis in prostate cancer cells
-
Bowen C, Voeller H, Kiklv K and Gelmann E: Synthesis of procaspases-3 and -7 during apoptosis in prostate cancer cells. Cell Death Differ 6(5): 394-401, 1999.
-
(1999)
Cell Death Differ
, vol.6
, Issue.5
, pp. 394-401
-
-
Bowen, C.1
Voeller, H.2
Kiklv, K.3
Gelmann, E.4
-
8
-
-
0035987541
-
CTL: Caspases terminate life, but that's not the whole story
-
Waterhouse N and Trapani J: CTL: Caspases terminate life, but that's not the whole story. Tissue Antigens 59(3): 175-83, 2002.
-
(2002)
Tissue Antigens
, vol.59
, Issue.3
, pp. 175-183
-
-
Waterhouse, N.1
Trapani, J.2
-
9
-
-
0033375493
-
The molecular mechanism of programmed cell death in C. elegans
-
Liu Q and Hengartner M: The molecular mechanism of programmed cell death in C. elegans. Ann NY Acad Sci 887: 92-104, 1999.
-
(1999)
Ann NY Acad Sci
, vol.887
, pp. 92-104
-
-
Liu, Q.1
Hengartner, M.2
-
10
-
-
0037052687
-
Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells
-
Ruefli A, Bernhard D, Tainton K, Kofler R, Smyth M and Johnstone R: Suberoylanilide hydroxamic acid (SAHA) overcomes multidrug resistance and induces cell death in P-glycoprotein-expressing cells. Int J Cancer 99(2): 292-8, 2002.
-
(2002)
Int J Cancer
, vol.99
, Issue.2
, pp. 292-298
-
-
Ruefli, A.1
Bernhard, D.2
Tainton, K.3
Kofler, R.4
Smyth, M.5
Johnstone, R.6
-
11
-
-
0032950954
-
P-glycoprotein protects leukaemia cells against caspase-dependent, but not caspase-independent cell death
-
Johnstone R, Cretney E and Smyth M: P-glycoprotein protects leukaemia cells against caspase-dependent, but not caspase-independent cell death. Blood 93(2): 1075-1085, 1999.
-
(1999)
Blood
, vol.93
, Issue.2
, pp. 1075-1085
-
-
Johnstone, R.1
Cretney, E.2
Smyth, M.3
-
12
-
-
0019856947
-
In vitro splicing of the ribosomal RNA precursor of Tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequence
-
Cech T, Zaug A and Grabowski P: In vitro splicing of the ribosomal RNA precursor of Tetrahymena: involvement of a guanosine nucleotide in the excision of the intervening sequence. Cell 27: 487-496, 1981.
-
(1981)
Cell
, vol.27
, pp. 487-496
-
-
Cech, T.1
Zaug, A.2
Grabowski, P.3
-
13
-
-
0036863325
-
Ribozymes, the first 20 years
-
Cech T: Ribozymes, the first 20 years. Biochem Soc Trans 30(6): 1162-6, 2001.
-
(2001)
Biochem Soc Trans
, vol.30
, Issue.6
, pp. 1162-1166
-
-
Cech, T.1
-
14
-
-
0036819772
-
The power of ribozyme technologies: The logical way ahead for molecular medicine and gene therapy?
-
Freelove A and Zheng R: The power of ribozyme technologies: the logical way ahead for molecular medicine and gene therapy? Curr Opin Mol Therap 4(5): 419-22, 2002.
-
(2002)
Curr Opin Mol Therap
, vol.4
, Issue.5
, pp. 419-422
-
-
Freelove, A.1
Zheng, R.2
-
15
-
-
0029294686
-
Improvement of hammerhead ribozymes cleaving mdr-1 mRNA
-
Palfner K, Kneb, M, Hiddemann W and Bertram J: Improvement of hammerhead ribozymes cleaving mdr-1 mRNA. Biol Chem Hoppe-Seyler 376: 289-295, 1995.
-
(1995)
Biol Chem Hoppe-Seyler
, vol.376
, pp. 289-295
-
-
Palfner, K.1
Kneb, M.2
Hiddemann, W.3
Bertram, J.4
-
16
-
-
0032568597
-
Structural basis for heterogeneous kinetics: Reengineering the hairpin ribozyme
-
Esteban J, Walter N, Kotzorek G, Heckman J and Burke J: Structural basis for heterogeneous kinetics: Reengineering the hairpin ribozyme. Proc Natl Acad Sci USA 95: 6091-6096, 1998.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 6091-6096
-
-
Esteban, J.1
Walter, N.2
Kotzorek, G.3
Heckman, J.4
Burke, J.5
-
17
-
-
0036864329
-
Mechanism of action of hammerhead ribozymes and their applications in vivo: Rapid identification of functional genes in the post-genome era by novel hybrid ribozyme libraries
-
Takagi Y, Suyama E, Kawasaki H, Miyagishi M and Taira K: Mechanism of action of hammerhead ribozymes and their applications in vivo: rapid identification of functional genes in the post-genome era by novel hybrid ribozyme libraries. Biochemical Soc Trans 30(6):1145-9, 2001.
-
(2001)
Biochemical Soc Trans
, vol.30
, Issue.6
, pp. 1145-1149
-
-
Takagi, Y.1
Suyama, E.2
Kawasaki, H.3
Miyagishi, M.4
Taira, K.5
-
18
-
-
0036864328
-
Intracellular ribozyme applications
-
Castanotto D, Li J, Michienzi A, Langlois M, Lee N, Puymirat J and Rossi J: Intracellular ribozyme applications. Biochemical Soc Trans 30(6): 1140-5, 2001.
-
(2001)
Biochemical Soc Trans
, vol.30
, Issue.6
, pp. 1140-1145
-
-
Castanotto, D.1
Li, J.2
Michienzi, A.3
Langlois, M.4
Lee, N.5
Puymirat, J.6
Rossi, J.7
-
19
-
-
0037062949
-
The chemical repertoire of natural ribozymes
-
Doudna J and Cech T: The chemical repertoire of natural ribozymes. Nature 418 (6894): 222-8, 2002.
-
(2002)
Nature
, vol.418
, Issue.6894
, pp. 222-228
-
-
Doudna, J.1
Cech, T.2
-
20
-
-
0034004474
-
Ribozyme-mediated inhibition of caspase-3 protects cerebellar granule cells from apoptosis induced by serum-potassium deprivation
-
Eldadah B, Ren R and Faden A: Ribozyme-mediated inhibition of caspase-3 protects cerebellar granule cells from apoptosis induced by serum-potassium deprivation. J Neuroscience 20 (1): 179-186, 2000.
-
(2000)
J Neuroscience
, vol.20
, Issue.1
, pp. 179-186
-
-
Eldadah, B.1
Ren, R.2
Faden, A.3
-
21
-
-
0035957767
-
Ribozyme-mediated inhibition of caspase-3 activity reduces apoptosis induced by 6-hydroxydopamine in PC 12 cells
-
Xu RH, Lie J, Chen XW, Xu F, Xie Q, Yu H, Guo Q, Zhou XQ and Jin YX: Ribozyme-mediated inhibition of caspase-3 activity reduces apoptosis induced by 6-hydroxydopamine in PC12 cells. Brain Res 899: 10-19, 2001.
-
(2001)
Brain Res
, vol.899
, pp. 10-19
-
-
Xu, R.H.1
Lie, J.2
Chen, X.W.3
Xu, F.4
Xie, Q.5
Yu, H.6
Guo, Q.7
Zhou, X.Q.8
Jin, Y.X.9
-
22
-
-
0030762122
-
Cross-resistance of CD95- and drug-induced apoptosis is a consequence of deficient activation of caspases (ICE/Ced-3 proteases)
-
Los M, Herr I, Friesen C, Fulda S, Schulze-Osthoff K and Debatin KM: Cross-resistance of CD95- and drug-induced apoptosis is a consequence of deficient activation of caspases (ICE/Ced-3 proteases). Blood 90(8): 3118-3129, 1997.
-
(1997)
Blood
, vol.90
, Issue.8
, pp. 3118-3129
-
-
Los, M.1
Herr, I.2
Friesen, C.3
Fulda, S.4
Schulze-Osthoff, K.5
Debatin, K.M.6
-
23
-
-
0026762310
-
Cytogenetic comparison of 2 poorly differentiated human lung squamous cell carcinoma cell lines
-
Law E, Gilvarry U, Grant G, Gregory B and Clynes M: Cytogenetic comparison of 2 poorly differentiated human lung squamous cell carcinoma cell lines. Cancer Gen Cytogenet 59: 111-118, 1992.
-
(1992)
Cancer Gen Cytogenet
, vol.59
, pp. 111-118
-
-
Law, E.1
Gilvarry, U.2
Grant, G.3
Gregory, B.4
Clynes, M.5
-
24
-
-
0031929323
-
Human lung carcinoma cell line DLKP contains 3 distinct subpopulations with different growth and attachment properties
-
McBride S, Meleady P, Baird A, Dinsdale D and Clynes M: Human lung carcinoma cell line DLKP contains 3 distinct subpopulations with different growth and attachment properties. Tumor Biology 19(2): 88-103, 1998.
-
(1998)
Tumor Biology
, vol.19
, Issue.2
, pp. 88-103
-
-
McBride, S.1
Meleady, P.2
Baird, A.3
Dinsdale, D.4
Clynes, M.5
-
25
-
-
0030915004
-
Isolation from a human MDR lung cell line of multiple clonal populations which exhibit significantly different drug resistance
-
Heenan M, O'Driscoll L, Cleary I, Connolly L and Clynes M: Isolation from a human MDR lung cell line of multiple clonal populations which exhibit significantly different drug resistance. Int J Cancer 71(5): 907-15, 1997.
-
(1997)
Int J Cancer
, vol.71
, Issue.5
, pp. 907-915
-
-
Heenan, M.1
O'Driscoll, L.2
Cleary, I.3
Connolly, L.4
Clynes, M.5
-
26
-
-
0025731211
-
A comparison of optimal and suboptimal RNA secondary structures predicted by free energy minimization with structures determined by phylogenetic comparison
-
Zuker M, Jaeger JA and Turner DH: A comparison of optimal and suboptimal RNA secondary structures predicted by free energy minimization with structures determined by phylogenetic comparison. Nucleic Acids Res 19(10): 2707-14, 1991.
-
(1991)
Nucleic Acids Res
, vol.19
, Issue.10
, pp. 2707-2714
-
-
Zuker, M.1
Jaeger, J.A.2
Turner, D.H.3
-
28
-
-
0028990125
-
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari M, Quan LT, O'Rourke K, Desnoyers S, Zeng Z, Beidler DR, Poirier GG, Salvesen GS and Dixit VM: Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81(5): 801-9, 1995.
-
(1995)
Cell
, vol.81
, Issue.5
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirier, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
29
-
-
0030822629
-
Development of a hammerhead ribozyme against bcl-2. 1. Preliminary evaluation of a potential gene therapeutic agent for hormone-refractory human prostate cancer
-
Dorai T, Olsson C, Katz A and Buttyan R: Development of a hammerhead ribozyme against bcl-2. 1. Preliminary evaluation of a potential gene therapeutic agent for hormone-refractory human prostate cancer. The Prostate 32: 246-258, 1997.
-
(1997)
The Prostate
, vol.32
, pp. 246-258
-
-
Dorai, T.1
Olsson, C.2
Katz, A.3
Buttyan, R.4
-
30
-
-
0001717745
-
Ribozyme-mediated site-specific cleavage of the HIV-1 genome
-
Chang P, Cantin E, Zaia J, Ladne P, Stephens D, Sarver N and Rossi J: Ribozyme-mediated site-specific cleavage of the HIV-1 genome. Clinical Biotechnology 2: 1, 1990.
-
(1990)
Clinical Biotechnology
, vol.2
, pp. 1
-
-
Chang, P.1
Cantin, E.2
Zaia, J.3
Ladne, P.4
Stephens, D.5
Sarver, N.6
Rossi, J.7
-
31
-
-
0034327531
-
Secondary structure prediction and in vitro accessibility of mRNA as tools in the selection of target sites for ribozymes
-
Amarzguioui M, Brede G, Babaie E, Grotli M, Sproat B and Prydz H: Secondary structure prediction and in vitro accessibility of mRNA as tools in the selection of target sites for ribozymes. Nucleic Acids Res 28(21): 4113-4124, 2000.
-
(2000)
Nucleic Acids Res
, vol.28
, Issue.21
, pp. 4113-4124
-
-
Amarzguioui, M.1
Brede, G.2
Babaie, E.3
Grotli, M.4
Sproat, B.5
Prydz, H.6
-
32
-
-
1842870632
-
The size of hammerhead ribozymes is related to cleavage kinetics: The role of substrate length
-
Hormes R and Sczakiel G: The size of hammerhead ribozymes is related to cleavage kinetics: the role of substrate length. Biochimie 84(9): 897-903, 2002.
-
(2002)
Biochimie
, vol.84
, Issue.9
, pp. 897-903
-
-
Hormes, R.1
Sczakiel, G.2
-
33
-
-
0036440685
-
The role of magnesium ions and 2'hydroxyl groups in the VS ribozyme-substrate interaction
-
Tzokov S, Murray I and Grasby J: The role of magnesium ions and 2'hydroxyl groups in the VS ribozyme-substrate interaction. J Mol Biol 324(2): 215-26, 2002.
-
(2002)
J Mol Biol
, vol.324
, Issue.2
, pp. 215-226
-
-
Tzokov, S.1
Murray, I.2
Grasby, J.3
-
34
-
-
0031973036
-
The Therapeutic Potential of Ribozymes
-
James HA and Gibson I: The Therapeutic Potential of Ribozymes. Blood 91(2): 371-382, 1998.
-
(1998)
Blood
, vol.91
, Issue.2
, pp. 371-382
-
-
James, H.A.1
Gibson, I.2
-
35
-
-
0035006895
-
Transfection of caspase-3 in the caspase-3-deficient Hodgkin's disease cell line, KMH2, results in enhanced sensitivity to CD95-, TRAIL-, and ARA-C-induced apoptosis
-
Wrone-Smith T, Izban K, Ergin M, Cosar E, His E and Alkan S: Transfection of caspase-3 in the caspase-3-deficient Hodgkin's disease cell line, KMH2, results in enhanced sensitivity to CD95-, TRAIL-, and ARA-C-induced apoptosis. Exp Hematol 29: 572-581, 2001.
-
(2001)
Exp Hematol
, vol.29
, pp. 572-581
-
-
Wrone-Smith, T.1
Izban, K.2
Ergin, M.3
Cosar, E.4
His, E.5
Alkan, S.6
-
36
-
-
0032403016
-
VEGF inhibits apoptosis death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing Mcl-1 acting as an anti-apoptotic factor
-
Katoh O, Takahashi T, Oguri T, Kuramoto K, Mihara K, Kobayashi M, Hirata S and Watanabe H: VEGF inhibits apoptosis death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing Mcl-1 acting as an anti-apoptotic factor. Cancer Res 58: 5565-5569, 1998.
-
(1998)
Cancer Res
, vol.58
, pp. 5565-5569
-
-
Katoh, O.1
Takahashi, T.2
Oguri, T.3
Kuramoto, K.4
Mihara, K.5
Kobayashi, M.6
Hirata, S.7
Watanabe, H.8
-
37
-
-
0032970751
-
Modeling the chemoprotective functions of glutathione S-transferases in cultured cell lines by heterologous expression
-
Townsend AJ, Fields WR, Doss AJ, Clapper ML, Doehmer J and Morrow CS: Modeling the chemoprotective functions of glutathione S-transferases in cultured cell lines by heterologous expression. Drug Metab Rev 31(1): 43-69, 1999.
-
(1999)
Drug Metab Rev
, vol.31
, Issue.1
, pp. 43-69
-
-
Townsend, A.J.1
Fields, W.R.2
Doss, A.J.3
Clapper, M.L.4
Doehmer, J.5
Morrow, C.S.6
-
38
-
-
0035825596
-
The involvement of PI 3-K/Akt-dependent up-regulation of mcl-1 in the prevention of apoptosis of Hel3B cells by interleukin-6
-
Kuo ML, Chuang SE, Lin MT and Yang SY: The involvement of PI 3-K/Akt-dependent up-regulation of mcl-1 in the prevention of apoptosis of Hel3B cells by interleukin-6. Oncogene 20: 677-685, 2001.
-
(2001)
Oncogene
, vol.20
, pp. 677-685
-
-
Kuo, M.L.1
Chuang, S.E.2
Lin, M.T.3
Yang, S.Y.4
-
39
-
-
0035901938
-
Over-expression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance
-
Friedrich K, Wieder T, Von Haefen C, Radetzki S, Janicke R, Schulze-Osthoff K, Dorken B and Daniel PT: Over-expression of caspase-3 restores sensitivity for drug-induced apoptosis in breast cancer cell lines with acquired drug resistance. Oncogene 20(22): 2749-60, 2001.
-
(2001)
Oncogene
, vol.20
, Issue.22
, pp. 2749-2760
-
-
Friedrich, K.1
Wieder, T.2
Von Haefen, C.3
Radetzki, S.4
Janicke, R.5
Schulze-Osthoff, K.6
Dorken, B.7
Daniel, P.T.8
-
40
-
-
0036021902
-
Viruses as gene delivery vectors: Application to gene function, target validation, and assay development
-
Lotze M and Kost T: Viruses as gene delivery vectors: Application to gene function, target validation, and assay development. Cancer Gene Therapy 9: 692-699, 2002.
-
(2002)
Cancer Gene Therapy
, vol.9
, pp. 692-699
-
-
Lotze, M.1
Kost, T.2
-
41
-
-
0036215654
-
Effective gene transfer to solid tumours using different nonviral gene delivery techniques: Electroporation, liposomes, and integrin-targeted vector
-
Cemazar M, Sersa G, Wilson J, Tozer G, Hart S, Grosel A and Dachs G: Effective gene transfer to solid tumours using different nonviral gene delivery techniques: Electroporation, liposomes, and integrin-targeted vector. Cancer Gene Therapy 9: 399-416, 2002.
-
(2002)
Cancer Gene Therapy
, vol.9
, pp. 399-416
-
-
Cemazar, M.1
Sersa, G.2
Wilson, J.3
Tozer, G.4
Hart, S.5
Grosel, A.6
Dachs, G.7
-
42
-
-
85047695997
-
Purging of chronic myelogenous leukaemia cells by retrovirally expressed anti-bcr-abl ribozymes with specific cellular compartmentalization
-
Mendoza-Maldonado R, Zentilin L, Fanin R and Giacca M: Purging of chronic myelogenous leukaemia cells by retrovirally expressed anti-bcr-abl ribozymes with specific cellular compartmentalization. Cancer Gene Therapy 9: 71-86,2002.
-
(2002)
Cancer Gene Therapy
, vol.9
, pp. 71-86
-
-
Mendoza-Maldonado, R.1
Zentilin, L.2
Fanin, R.3
Giacca, M.4
-
43
-
-
0034643253
-
Resistance to apoptosis is correlated with the reduced caspase-3 activation and enhanced expression of antiapoptotic proteins in human cervical multidrug-resistant cells
-
Ding Z, Yang X, Pater A and Tang S: Resistance to apoptosis is correlated with the reduced caspase-3 activation and enhanced expression of antiapoptotic proteins in human cervical multidrug-resistant cells. Biochem Biophys Res Commun 270(2): 415-20, 2000.
-
(2000)
Biochem Biophys Res Commun
, vol.270
, Issue.2
, pp. 415-420
-
-
Ding, Z.1
Yang, X.2
Pater, A.3
Tang, S.4
-
44
-
-
0034765627
-
Apoptosis and the response to anticancer therapy
-
Mow B, Blajeski AL, Chandra J and Kaufmann SH: Apoptosis and the response to anticancer therapy. Curr Opin Oncol. 13(6): 453-62, 2001.
-
(2001)
Curr Opin Oncol
, vol.13
, Issue.6
, pp. 453-462
-
-
Mow, B.1
Blajeski, A.L.2
Chandra, J.3
Kaufmann, S.H.4
-
45
-
-
0029829944
-
MDR-1 ribozyme mediated reversal of the multi-drug resistant phenotype in human lung cell lines
-
Daly C, Coyle S, McBride S, O'Driscoll L, Daly N, Scanlon K and Clynes M: MDR-1 ribozyme mediated reversal of the multi-drug resistant phenotype in human lung cell lines. Cytotechnology 19: 199-205, 1996.
-
(1996)
Cytotechnology
, vol.19
, pp. 199-205
-
-
Daly, C.1
Coyle, S.2
McBride, S.3
O'Driscoll, L.4
Daly, N.5
Scanlon, K.6
Clynes, M.7
|