Comparative responses of three rat strains (DA/Han, Sprague-Dawley and Wistar) to treatment with environmental estrogens

Archives of Toxicology

Volumn 78, Issue 4, 2004, Pages 183-193

  Diel, P ^a   Schmidt, S ^a   Vollmer, G ^b   Janning, P ^c   Upmeier, A ^c   Michna, H ^a   Bolt, H M ^c   Degen, G H ^c  

^a GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

^b DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^c LEIBNIZ RESEARCH CENTRE FOR WORKING ENVIRONMENT AND HUMAN FACTORS   (Germany)

Author keywords

Bisphenol A; Clusterin; DA Han rat; Genistein; p tert Octylphenol; Sprague Dawley rat; Uterus; Vagina; Wistar rat

Indexed keywords

4 TERT OCTYLPHENOL; 4,4' ISOPROPYLIDENEDIPHENOL; CLUSTERIN; ESTRADIOL; GENISTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOMETRIUM; ESTROGEN ACTIVITY; FEMALE; GENE EXPRESSION; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; STRAIN DIFFERENCE; UTERUS WEIGHT; VAGINA EPITHELIUM;

RATTUS NORVEGICUS;

EID: 2442519070     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-003-0535-y     Document Type: Article

References (51)

1. Bolt HM, Degen GH, Michna H (2002) Approaches to comparative risk evaluation. Proceedings of the 2nd Status -Seminar "Endocrine Disruptors", Berlin, 2-4 April 2001, pp 151-154. Available online at htpp://www.status-umwelthormone.de
2. Christian MS, Hoberman AM, Bachmann S, Hellwig J (1998) Variability in the uterotrophic response assay (an in vivo estrogenic response assay) in untreated control and positive control (DES-DP, 2.5 μg/kg, bid) Wistar and Sprague-Dawley rats. Drug Chem Toxicol 21 [Suppl 1]:51-100
3. Degen GH, Bolt HM (2000) Endocrine disruptors: update on xenoestrogens. Int Arch Occup Environ Health 73:433-441
4. Degen GH, Bolt HM (2002) Comparative investigation of synthetic estrogens and phytoestrogens - general concept and research strategy. Proceedings of the 2nd Status -Seminar "Endocrine Disruptors", Berlin, 2-4 April 2001, pp 137-140. Available online at htpp://www.status-umwelthormone.de
5. Degen GH, Bolt HM (2003) Endocrine disruptors: environmental estrogenic compounds. In: Schneider HP et al. (eds) Menopause: the state of the art - research and practice. Parthenon Publishers, Lancaster UK, pp 307-311
6. Degen GH, Janning P, Wittsiepe J, Upmeier A, Bolt HM (2002a) Integration of mechanistic data in the toxicological evaluation of endocrine modulators. Toxicol Lett 127:225-237
7. Degen GH Janning P, Diel P, Bolt HM (2002b) Estrogenic isoflavones in rodent diets. Toxicol Lett 128:145-157
8. Degen GH, Janning P, Diel P, Michna H, Bolt HM (2002c) Transplacental transfer of the phytoestrogen daidzein. Arch Toxicol 76:23-29
9. Diel P (2002) Tissue-specific estrogenic response and molecular mechanisms. Toxicol Lett 127:217-224
10. Diel P, Schulz T, Smolnikar K, Strunck E, Vollmer G, Michna H (2000) Ability of xeno- and phytoestrogens to modulate expression of estrogen-sensitive genes in rat uterus: estrogenicity profiles and uterotropic activity. J Steroid Biochem Mol Biol 73:1-10
11. Diel P, Smolnikar K, Schulz T, Laudenbach-Leschowski U, Michna H, Vollmer G (2001) Phytoestrogens and carcinogenesis - differential effects of genistein in experimental models of normal and malignant rat endometrium. Hum Reprod 16:997-1006
12. Diel P, Schmidt S, Vollmer G (2002) In vivo systems for the quantitative and qualitative analysis of the biological activity of phytoestrogens. J Chromatogr B Analyt Technol Biomed Life Sci 777:191-202
13. EDSTAC (1999) Endocrine Disruptor Screening and Testing Advisory Committee (EDSTAC) Final Report. Available online at http://www.epa.gov/Scipoly/ oscpendo/history/final-rpt.htm
14. European Commission (1997) European workshop on the impact of endocrine disrupters on human health and wildlife. Report of Proceedings. 2-4 December 1996, Weybridge UK, Publication EUR 17549
15. Hopert AC, Beyer A, Frank K, Strunck E, Wünsche W, Vollmer G (1998) Characterization of estrogenicity of phytoestrogens in an endometrial-derived experimental model. Environ Health Perspect 106:581-586
16. Janning P, Schuhmacher US, Upmeier A, Diel P, Michna H, Degen GH, Bolt HM (2000) Toxicokinetics of the phytoestrogen daidzein in female DA/Han rats. Arch Toxicol 74:421-430
17. Kang KS, Kim HS, Ryu DY, Che JH, Lee YS (2000) Immature uterotrophic assay is more sensitive than ovariectomized uterotrophic assay for the detection of estrogenicity of p-nonylphenol in Sprague-Dawley rats. Toxicol Lett 118:109-115
18. Kanno J, Onyon L, Haseman J, Fenner-Crisp P, Ashby J, Owens W (2001) The OECD program to validate the rat uterotrophic bioassay to screen compounds for in vivo estrogenic responses: phase 1. Environ Health Perspect 109:785-794
19. Kanno J, Kato H, Iwata T, Inoue T (2002) Phytoestrogen-low diet for endocrine disruptor studies. J Agr Food Chem 50:3883-3885
20. Kanno J, Onyon L, Peddada S, Ashby J, Jacob E, Owens W (2003a) The OECD program to validate the rat uterotrophic bioassay. Phase 2: dose-response studies. Environ Health Perspect 111:1530-1549
21. Kanno J, Onyon L, Peddada S, Ashby J, Jacob E, Owens W (2003b) The OECD program to validate the rat uterotrophic bioassay. Phase 2: coded single-dose studies. Environ Health Perspect 111:1550-1558
22. Knauthe R, Diel P, Hegele-Hartung C, Engelhaupt A, Fritzemeier KH (1996) Sexual dimorphism of steroid hormone receptor messenger ribonucleic acid expression and hormonal regulation in rat vascular tissue. Endocrinology 137:3220-3227
23. Laws SC, Carey SA, Ferrell JM, Bodman GJ, Cooper RL (2000) Estrogenic activity of octylphenol, nonylphenol, bisphenol A and methoxychlor in rats. Toxicol Sci 54:154-167
24. Long X, Steinmetz R, Ben-Jonathan N, Caperell-Grant A, Young PC, Nephew KP, Bigsby RM (2000) Strain differences in vaginal responses to the xenoestrogen bisphenol A. Environ Health Perspect 108:243-247
25. Mäkelä, S., Hyder, S.M., Stancel, G.M., 1999. Environmental estrogens. In: Oettel, M., Schillinger, E. (eds) Estrogens and antiestrogens, handbook of experimental pharmacology, vol 135/11. Springer, Heidelberg Berlin New York, pp 613-663
26. McKim JM Jr, Wilga PC, Breslin WJ, Plotzke KP, Gallavan RH, Meeks RG (2001) Potential estrogenic and antiestrogenic activity of the cyclic siloxane octamethylcyclosiloxane (D4) and the linear siloxane hexamethyldisiloxane (HMDS) in immature rats using the uterotrophic assay. Toxicol Sci 63:37-46
27. Mehmood Z, Smith AG, Tucker MJ, Chuzel F, Carmichael NG (2000) The development of methods for assessing the in vivo oestrogen-like effects of xenobiotics in CD-1 mice. Food Chem Toxicol 38:493-501
28. Murphy LD, Herzog CE, Rudick JB, Fojo AT, Bates SE (1990) Use of the polymerase chain reaction in the quantitation of mdr-1 gene expression. Biochemistry 29:10351-10356
29. National Research Council (1999) Hormonally active agents in the environment. National Academy Press, Washington DC
30. Newbold RR Jefferson WN, Padilla-Banks E, Walker VR, Pena DS (2001) Cell response endpoints enhance sensitivity of the immature mouse uterotropic assay. Reprod Toxicol 15:245-252 [Erratum ibid, pp 465-466]
31. Newbold RR Jefferson WN, Padilla-Banks E, Walker VR, Pena DS (2001) Cell response endpoints enhance sensitivity of the immature mouse uterotropic assay. Reprod Toxicol 15:245-252 [Erratum ibid, pp 465-466]
32. O'Connor JC, Cook JC, Slone TW, Makovec GT, Frame SR, Davis LG (1998a) An ongoing validation of a Tier I screening battery for detecting endocrine-active compounds (EACs). Toxicol Sci 46:45-60
33. O'Connor JC, Frame SR, Siegel LB, Cook JC, Davis LG (1998b) Sensitivity of a Tier I screening battery compared to an in utero exposure for detecting the estrogen receptor agonist 17β-estradiol. Toxicol Sci 44:169-184
34. Odum J, Lefevre PA, Tittensor S, Paton D, Routledge EJ, Beresford NA, Sumpter JP, Ashby J (1997) The rodent uterotrophic assay: critical protocol features, studies with nonyl phenols, and comparison with yeast estrogenicity assay. Regul Toxicol Pharmacol 25:176-188
35. Odum J, Pyrah IT, Foster JR, Van Miller JP, Joiner RL, Ashby J (1999a) Comparative activities of p-nonylphenol and diethylstilbestrol in Noble rat mammary gland and uterotrophic assays. Regul Toxicol Pharmacol 29:184-195
36. Odum J, Pyrah IT, Soames AR, Foster JR, Van Miller JP, Joiner RL, Ashby J (1999b) Effects of p-nonylphenol (NP) and diethylstilbestrol (DES) on the Alderley Park (Alpk) rat: comparison of mammary gland and uterus sensitivity following oral gavage or implanted mini-pumps. J Appl Toxicol 19:367-378.
37. OECD (Organisation for Economic Cooperation and Development) (2001). Third meeting of the validation management group for the screening and testing of endocrine disrupters (mammalian effects). Document ENV/JM/TG/EDTA Paris: Joint meeting of the chemicals committee and the working party on chemicals, pesticides and biotechnology
38. Owens W, Ashby J (2002) Critical review and evaluation of the uterotrophic bioassay for the identification of possible estrogen agonists and antagonists: in support of the validation of the OECD uterotrophic protocols for the laboratory rat. Crit Rev Toxicol 32:445-520
39. Owens W, Koeter HB (2003) The OECD program to validate the uterotrophic bioassay: an overview. Environ Health Perspect 111:1527-1529
40. Owens W, Ashby J, Odum J, Onyon L (2003) The OECD program to validate the rat uterotrophic bioassay. Phase 2: Dietary phytoestrogen analyses. Environ Health Perspect 111:1559-1567
41. Reel JR, Lamb J, Neal BH (1996) Survey and assessment of mammalian estrogen biological assays for hazard characterization. Fundam Appl Toxicol 34:288-305
42. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning - a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory Press, Cold Spring Harbor FL
43. Steinmetz R, Mitchner NA, Grant A, Allen DL, Bigsby RM, Ben-Jonathan N (1998) The xenoestrogen bisphenol A induces growth, differentiation, and c-fos gene expression in the female reproductive trat. Endocrinology 139:2741-2747
44. Strunck E, Hopert AC, Frank K, Schiffmann D, Vollmer G (1998) An endometrium-derived tumor model detects differential potency of phytoestrogens. In: Dunaif GE, Olin SS., Scimeca J, Thomas JA (eds) Human diet and endocrine modulation: estrogenic and androgenic effects. ILSI Press, Washington DC, pp 281-285
45. Thigpen JE, Haseman JK, Saunders H, Locklear J, Caviness G, Grant M, Forsythe D (2002) Dietary factors affecting uterine weights of immature CD-mice used in uterotrophic assays. Cancer Detect Prev 26:381-393
46. Upmeier A, Degen GH, Diel P, Michna H, Bolt HM (2000) Toxicokinetics of bisphenol A in female DA/Han rats after single i.v. and oral application. Arch Toxicol 74:431-436
47. Vollmer G, Schneider MR (1996) The rat endometrial adenocarcinoma cell line RUCA-I: a novel hormone-sensitive in vivo/in vitro tumor model. J Steroid Biochem Mol Biol 58:103-115
48. Vollmer G, Ellerbrake N, Hopert AC, Knauthe R, Wünsche W, Knuppen R (1995) Extracellular matrix induces hormone responsiveness and differentiation in RUCA-I rat endometrial adenocarcinoma cells. J Steroid Biochem Mol Biol 52:259-269
49. Wünsche W, Tenniswood MP, Schneider MR, Vollmer G (1998) Estrogenic regulation of clusterin mRNA in normal and malignant endometrial tissue. Int J Cancer 76:684-688.
50. Yamasaki K, Sawaki M, Takatsuki M (2000) Immature rat uterotrophic assay of bisphenol A. Environ Health Perspect 108:1147-1150
51. Yamasaki K, Sawaki M, Noda S, Wada T, Hara T, Takatsuki M (2002) Immature uterotrophic assay of estrogenic compounds in rats given diets of different phytoestrogen content and the ovarian changes with ICI 182,870 or antide. Arch Toxicol 76:613-620