Analysis of polymorphisms at the tumor suppressor gene p53 (TP53) in contributing to the risk for schizophrenia and its associated neurocognitive deficits

Neuroscience Letters

Volumn 363, Issue 1, 2004, Pages 78-80

  Papiol, Sergi ^a   Arias, Bárbara ^a   Barrantes Vidal, Neus ^b   Guitart, Marc ^a   Salgado, Purificación ^c   Catalán, Rosa ^d   Fañanás, Lourdes ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^c Inst Munic de Psiq d'Urgencies   (Spain)

^d HOSPITAL CLÍNIC   (Spain)

Author keywords

Neurocognition; Neurodegeneration; Neurodevelopment; p53; Polymorphism; Schizophrenia

Indexed keywords

ALLELE; ARTICLE; COGNITION; CONTROLLED STUDY; DISEASE ASSOCIATION; GENE; GENE LOCUS; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HUMAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RISK FACTOR; SCHIZOPHRENIA; TUMOR SUPPRESSOR P53 GENE;

ADULT; ALLELES; ARGININE; CHI-SQUARE DISTRIBUTION; COGNITION DISORDERS; DNA TRANSPOSABLE ELEMENTS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; POLYMORPHISM, GENETIC; PROLINE; RISK; SCHIZOPHRENIA; TUMOR SUPPRESSOR PROTEIN P53;

EID: 2442487801     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2004.03.049     Document Type: Article

References (25)

1. Aloyz R.S., Bamji S.X., Pozniak C.D., Toma J.G., Atwal J., Kaplan D.R., Miller F.D. p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors. J. Cell Biol. 143:1998;1691-1703
2. Benton A.L., Sivan A.B., Hamsher K.D.S., Varney N.R., Spreen O. Contributions to Neuropsychological Assessment. A Clinical Manual. 1994;Oxford University Press, New York
3. Cardno A.G., Marshall E.J., Coid B., Macdonald A.M., Ribchester T.R., Davies N.J., Venturi P., Jones L.A., Lewis S.W., Sham P.C., Gottesman I.I., Farmer A.E., McGuffin P., Reveley A.M., Murray R.M. Heritability estimates for psychotic disorders: the Maudsley twin psychosis series. Arch. Gen. Psychiatry. 56:1999;162-168
4. Catts V.S., Catts S.V. Apoptosis and schizophrenia: is the tumour suppressor gene, p53, a candidate susceptibility gene? Schizophr. Res. 41:2000;405-415
5. Chiu H.J., Wang Y.C., Chen J.Y., Hong C.J., Tsai S.J. Association study of the p53-gene Pro72Arg polymorphism in schizophrenia. Psychiatry Res. 105:2001;279-283
6. Cornblatt B.A., Lenzenweger M.F., Erlenmeyer-Kimling L. The continuous performance test, identical pairs version: II. Contrasting attentional profiles in schizophrenic and depressed patients. Psychiatry Res. 29:1989;65-85
7. DeLisi L.E. Is schizophrenia a lifetime disorder of brain plasticity, growth and aging? Schizophr. Res. 23:1997;119-129
8. De Quervain D.J., Henke K., Aerni A., Coluccia D., Wollmer M.A., Hock C., Nitsch R.M., Papassotiropoulos A. A functional genetic variation of the 5-HT2a receptor affects human memory. Nat. Neurosci. 6:2003;1141-1142
9. Dumont P., Leu J.I., Della Pietra A.C. 3rd, George D.L., Murphy M. The codon 72 polymorphic variants of p53 have markedly different apoptotic potential. Nat. Genet. 33:2003;357-365
10. Egan M.F., Goldberg T.E., Kolachana B.S., Callicott J.H., Mazzanti C.M., Straub R.E., Goldman D., Weinberger D.R. Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia. Proc. Natl. Acad. Sci. USA. 98:2001;6917-6922
11. Egan M.F., Kojima M., Callicott J.H., Goldberg T.E., Kolachana B.S., Bertolino A., Zaitsev E., Gold B., Goldman D., Dean M., Lu B., Weinberger D.R. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell. 112:2003;257-269
12. Giaccia A.J., Kastan M.B. The complexity of p53 modulation: emerging patterns from divergent signals. Genes Dev. 12:1998;2973-2983
13. Heaton R.K., Chelune G.J., Talley J.L., Kay G.G., Curtiss G. Wisconsin Card Sorting Test Manual. 1993;Psychological Assessment Resources, Odessa, FL
14. Levine A.J. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-331
15. Morrison R.S., Kinoshita Y., Johnson M.D., Guo W., Garden G.A. p53-dependent cell death signaling in neurons. Neurochem. Res. 28:2003;15-27
16. Murray R.M., Lewis S.W. Is schizophrenia a neurodevelopmental disorder? Br. Med. J. (Clin. Res. Ed.). 295:1987;681-682
17. Park J.K., Lee H.J., Kim J.W., Park Y.H., Lee S.S., Chang H.I., Song J.Y., Yoon D.J., Bahn G.H., Shin Y.H., Kim Y.J., Kim S.A., Choe B.K., Kim C.J., Chung J.H. Differences in p53 gene polymorphisms between Korean schizophrenia and lung cancer patients. Schizophr. Res. 67:2004;71-74
18. Rosenmann H., Meiner Z., Kahana E., Aladjem Z., Friedman G., Ben-Yehuda A., Grenader T., Wertman E., Abramsky O. An association study of the codon 72 polymorphism in the pro-apoptotic gene p53 and Alzheimer's disease. Neurosci. Lett. 340:2003;29-32
19. Saykin A.J., Shtasel D.L., Gur R.E., Kester D.B., Mozley L.H., Stafiniak P., Gur R.C. Neuropsychological deficits in neuroleptic naive patients with first-episode schizophrenia. Arch. Gen. Psychiatry. 51:1994;124-131
20. Schneider S., Kueffer J.M., Roessli D., Excoffier L. Arlequin ver. 1.1: A Software for Population Genetic Data Analysis. 1997;University of Geneva, Geneva
21. Vos M., Adams C.H., Victor T.C., van Helden P.D. Polymorphisms and mutations found in the regions flanking exons 5 to 8 of the TP53 gene in a population at high risk for esophageal cancer in South Africa. Cancer Genet. Cytogenet. 140:2003;23-30
22. Wechsler D. Wechsler Adult Intelligence Scale-III. 1991;The Psychological Corporation, New York
23. Wechsler D. WMS-R, Wechsler Memory Scale - Revised Manual. 1987;Harcourt Brace Jovanovich, New York
24. Weinberger D.R. Implications of normal brain development for the pathogenesis of schizophrenia. Arch. Gen. Psychiatry. 44:1987;660-669
25. Woods B.T., Yurgelun-Todd D., Goldstein J.M., Seidman L.J., Tsuang M.T. MRI brain abnormalities in chronic schizophrenia: one process or more? Biol. Psychiatry. 40:1996;585-596