MRI brain abnormalities in chronic schizophrenia: One process or more?

Biological Psychiatry

Volumn 40, Issue 7, 1996, Pages 585-596

  Woods, Bryan T ^a   Yurgelun Todd, Deborah ^b   Goldstein, Jill M ^a,c,d   Seidman, Larry J ^a,c,d   Tsuang, Ming T ^a,c,d,e  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b MCLEAN HOSPITAL   (United States)

^c MASSACHUSETTS MENTAL HEALTH CENTER   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

brain; frontal lobes; imaging; MRI; schizophrenia; temporal lobes

Indexed keywords

ADULT; ARTICLE; BRAIN GROWTH; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FRONTAL LOBE; HUMAN; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; PRIORITY JOURNAL; SCHIZOPHRENIA;

EID: 0030272977     PISSN: 00063223     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-3223(95)00478-5     Document Type: Article

References (63)

1. Abacus Concepts (1989): Super-ANOVA. Berkeley, CA: Abacus Concepts Inc.
2. Abi-Dargham A, Jasikaw G, Suddath RL, Weinberger DL (1991): Evidence against progression of in vivo anatomical abnormalities in schizophrenia. Schizophr Res 5:210.
3. Akbarian S, Bunney WE, Potkin SG, Wigal SB, Hagman JO, Sandman CA, Jones EG (1993): Altered distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase cells in frontal lobe of schizophrenics implies disturbances of cortical development. Arch Gen Psychiatry 50:169-177.
4. Akbarian S, Vinuela A, Kim JJ, Potkin SG, Bunney WE, Jones EG (1993): Distorted distribution of nicotinamide-adenine dinucleotide phosphate-diaphorase neurons in temporal lobe of schizophrenics implies anomalous cortical development. Arch Gen Psychiatry 50:178-187.
5. Alheid GF, Heimer L (1988): New Perspectives in basal forebrain organization of special relevance for neuropsychiatric disorders: The striatopallidal, amygdaloid, and corticopetal components of substantia innominata, Neuroscience 27:1-39.
6. American Psychiatric Association (1987): Diagnostic and Statistical Manual of Mental Disorders, 3rd ed rev. Washington DC: American Psychiatric Association.
7. Andreasen N, Nasrallah HA, Dunn V, Olson SC, Grove WM, Ehrhardt JC, Coffman JA, Crossett JHW (1986): Structural abnormalities in the frontal system in schizophrenia. Arch Gen Psychiatry 43:136-144.
8. Andreasen NC, Ehrhardt JC, Swayze VW, Alliger RJ, Yuh WTC, Cohen G, Ziebell S (1990): Magnetic resonance imaging of the brain in schizophrenia. Arch Gen Psychiatry 47:35-44.
9. Andreasen NC, Flashman L, Flaum M, Arndt S, Swayze V, O'Leary DS, Ehrhardt JC, Yuh WTC (1994): Regional brain abnormalities in schizophrenia measured with magnetic resonance imaging. JAMA 272:1763-1769.
10. Arndt S, Cohen G, Alliger RJ, Swayze VW, Andreasen NC (1991): Problems with ratio and proportion measures of imaged cerebral structures. Psychiatry Res Neuroimaging 40:79-89.
11. Arnold SE, Hyman BT, Van Hoesen GW, Damasio AR (1991): Some cytoarchitectural abnormalities of the entorhinal cortex in schizophrenia. Arch Gen Psychiatry 48:625-632.
12. Benes FM, McSparren J, Bird ED, SanGiovanni JP, Vincent SL (1991): Deficits in small interneurons in prefrontal and cingulate cortices of schizophrenic and schizoaffective patients. Arch Gen Psychiatry 48:996-1001.
13. Breier A, Schreiber JL, Dyer J, Pickar D (1991): National Institute of Mental Health longitudinal study of chronic schizophrenia. Arch Gen Psychiatry 48:239-246.
14. Breier A, Buchanan RW, Elkashef A, Munson RC, Kirkpatrick B, Gellad F (1992): Brain morphology and schizophrenia. Arch Gen Psychiatry 49:921-926.
15. Carson DA, Ribiero JM (1993): Apoptosis and Disease. Lancet 341:1251-1254.
16. Conrad AJ, Abebe T, Austin R, Forsythe S, Scheibel AB (1991): Hippocampal pyramidal cell disarray in schizophrenia as a bilateral phenomenon. Arch Gen Psychiatry 48:413-417.
17. DeLisi LE, Hoff AL, Schwartz JE, Shields GW, Halthore SN, Gupta SM, Henn FA, Anand AK (1991a): Brain morphology in first-episode schizophrenic-like psychotic patients: A quantitative magnetic resonance imaging study. Biol Psychiatry 29:159-175.
18. DeLisi LE, Strizke P, Riordan H, Holan V, Kushner M, Boccio A, van Eyl O, Anand A (1991b): The timing of morphological brain changes in schizophrenia: Do they progress? In Racagni IG et al (eds), Biological Psychiatry, Vol 1. Amsterdam: Elsevier.
19. Fleiss JL (1983): The Analysis of Rates and Proportions. New York: John Wiley & Sons.
20. Goldstein JM, Tsuang MT, Faraone SV (1989): Gender and schizophrenia: Implications for understanding the heterogeneity of the illness. Psychiatr Res 28:243-253.
21. Goldstein JM, Seidman LJ, Santangelo S, Knapp PH, Tsuang MT (1994): Are schizophrenic men at higher risk for developmental deficits than schizophrenic women? Implications for adult neuropsychological functions. J Psychiatr Res 28(6): 483-489.
22. Gur RE, Mozley D, Resnick SM, Shtasel D, Kohn M, Zimmerman R, Herman G, Atlas S, Grossman R, Erwin R, Gur RC (1991): Magnetic Resonance Imaging in schizophrenia. Arch Gen Psychiatry 48:407-412.
23. Gur RE, Mozley D, Shtasel D, Cannon TD, Gallacher F, Turetsky B, Grossman R, Gur RC (1994): Clinical subtypes of schizophrenia: Differences in brain and CSF volume. Am J Psychiatry 151:343-350.
24. Harvey I, Ron MA, Du Boulay G, Wicks D, Lewis SW, Murray RM (1993): Reduction of cortical volume in schizophrenia on magnetic resonance imaging. Psychol Med 23:591-604.
25. Huttenlocher PR (1979): Synaptic density in human frontal cortex: Developmental changes and effects of aging. Brain Res 163:195-205.
26. Illowsky BP, Juliano DM, Bigelow LB, Weinberger DR (1988): Stability of CT scan findings: Results of an 8-year follow-up study. J Neurol Neurosurg Psychiatry 51:209-213.
27. Jernigan TL, Zisook S, Heaton RK, Moranville JT, Hesselink JR, Braff DL (1991): Magnetic resonance imaging abnormalities in lenticular nuclei and cerebral cortex in schizophrenia. Arch Gen Psychiatry 48:881-890.
28. Kemali D, Maj M, Galderisi S, Milici N, Salvati A (1989): Ventricle-to-brain ratio in schizophrenia: A controlled follow-up study. Biol Psychiatry 26:753-756.
29. Kerr JF, Wyllie AH, Currie AR (1972): Apoptosis: A basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 26:239-257.
30. LaFosse JM, Mednick SA, Praestholm J, Vestergaard A, Parnas J, Schulsinger F (1994): The influence of parental socioeconomic status on CT studies of schizophrenia. Schizophr Res 11:285-290.
31. Lieberman J, Bogerts B, Degreef G, Ashtari M, Lantos G, Alvir J (1992): Qualitative assessment of brain morphology in acute and chronic schizophrenia. Am J Psychiatry 149:784-794.
32. Lim KO, Pfefferbaum A (1989): Segmentation of MR brain images into cerebrospinal fluid spaces, white and gray matter. J Comp Asst Tom 15:588-593.
33. Lim KO, Beal DM, Harvey RL Jr, Myers T, Lane B, Sullivan EV, Faustman WO, Pfefferbaum A (1995): Brain dysmorphology in adults with congenital rubella plus schizophrenialike symptoms. Biol Psychiatry 37:764-776.
34. Mathalon DH, Sullivan EV, Rawles JM, Pfefferbaum A (1993): Correction for head-size in brain-imaging measurements. Psychiatry Res: Neuroimaging 50:121-139.
35. Matsui T, Hirano A (1978): An atlas of the human brain for computerized tomography. Tokyo: Igaku-Shoin.
36. McGlashan TH (1988): A selective review of recent North American long-term follow-up studies of schizophrenia. Schizophr Bull 14:515-542.
37. Murray RM, O'Callaghan E, Castle DJ, Lewis SW (1992): A neurodevelopmental approach to the classification of schizophrenia. Schizophr Bull 18(2):319-332.
38. Nasrallah HA, Olson SC, McCalley-Whitters M, Chapman S, Jacoby CG (1986): Cerebral ventricular enlargement in schizophrenia: A preliminary follow-up study. Arch Gen Psychiatry 43:157-159.
39. Nieuwenhuys R, Voogd J, van Huijzen C (1988): The Human Central Nervous System, 3rd ed. Berlin: Springer-Verlag.
40. O'Callaghan E, Buckley P, Redmond O, Stack J, Ennis JT, Larkin C, Waddington JL (1992): Abnormalities of cerebral structure in schizophrenia on magnetic resonance imaging: interpretation in relation to the neurodevelopmental hypothesis. J Royal Soc Med 85:227-231.
41. Pearlson GD, Kim WS, Kubos KL, Moberg PJ, Jayaram G, Bascom MJ, Chase GA, Goldfinger AD, Tune LE (1989): Ventricle-brain ratio, computed tomographic density, and brain area in 50 schizophrenics. Arch Gen Psychiatry 46: 690-697.
42. Pearlson GD, Barta PE, Schraml FV, Chase GA, Tune LA (1991): Brain size in schizophrenia (letter). Arch Gen Psychiatry 48:180-181.
43. Pfefferbaum A, Zatz L, Jernigan TL (1986): Computer-interactive method for quantifying cerebrospinal fluid and tissue in brain CT scans: Effects of aging. J Comp Asst Tom 10:571-578.
44. Pfefferbaum A, Mathalon DH, Sullivan EV, Rawles JM, Zipursky RB, Lim KO (1994): A Quantitative magnetic resonance imaging study of changes in brain morphology from infancy to late adulthood. Arch Neurol 51:874-887.
45. Roberts GW (1991): Schizophrenia: A neuropathological perspective. Br J Psychiatry 158:8-17.
46. Rudolph AM, Hoffman JIE, Rudolph CD (1991): Rudolph's Pediatrics, 19th ed. Norwalk, CT: Appleton & Lange.
47. Schlaepfer TE, Harris GJ, Tien AY, Peng LW, Lee S, Federman EB, Chase GA, Barta PE, Pearlson GD (1994): Decreased regional cortical gray matter volume in schizophrenia. Am J Psychiatry 151:842-848.
48. Schwarzkopf SB, Olson SC, Coffman JA, Nasrallah HA (1990): Third and lateral ventricle volumes in schizophrenia: Support for progressive enlargement of both structures. Psychopharm Bull 26:385-391.
49. Schwarzkopf SB, Nasrallah HA, Olson SC, Bogerts B, McLaughlin JA, Mitra T (1991): Family history and brain morphology in schizophrenia: An MRI study. Psychiatry Res: Neuroimaging 40:49-60.
50. Seidman LJ, Yurgelun-Todd D, Kremen WS, Woods BT, Goldstein JM, Faraone SV, Tsuang MT (1994): Relationship of Prefrontal and temporal lobe MRI measures and neuropsychological performance in chronic schizophrenia. Biol Psychiatry 35:235-246.
51. Spitzer RL, Endicott J (1978): Schedule for Affective Disorders and Schizophrenia (SADS). New York: Biometrics Research.
52. Susser ES, Lim SP (1992): Schizophrenia after prenatal exposure to the Dutch hunger winter of 1944-1945. Arch Gen Psychiatry 49:982-988.
53. Taveras JM, Wood EH (1976): Diagnostic Neuroradiology, 2nd ed. Baltimore: Williams & Wilkins.
54. Vita A, Sacchetti E, Valvasori G, Cazzullo CL (1988): Brain morphology in schizophrenia: A 2-to 5-year follow-up study. Acta Psychiatrica Scand 78:618-621.
55. Weinberger DR (1984): Computed tomography (CT) findings in schizophrenia: Speculation on the meaning of it all. J Psychiatr Res 18:477-490.
56. Weinberger DR (1987): Implications of normal brain development for the pathogenesis of schizophrenia. Arch Gen Psychiatry 44:660-669.
57. Woods BT, Yurgelun-Todd D (1991): Brain volume loss in schizophrenia: When does it occur and is it progressive? Schizophr Res 5:202-204.
58. Woods BT, Yurgelun-Todd D, Benes FM, Frankenburg FR, Pope Jr HG, McSparrow J (1990): Progressive ventricular enlargement in correlation with clinical course. Biol Psychiatry 27:341-352.
59. Woods BT, Yurgelun-Todd D, Goldstein J, Tsuang M (1991): Volumetric measurements of cerebral gray and white matter and cerebrospinal fluid (CSF) space in chronic schizophrenic patients and controls (Abstr). Schizophr Res 4:414.
60. Yakovlev PI, Lecours A (1967): The myelogenetic cycles of regional maturation of the brain. In Minkowski A (ed), Regional Development of the Brain in Early Life. Oxford, England: Blackwell.
61. Zilkha A (1980): CT of cerebral hemiatrophy. ANJR 1:255-258.
62. Zipursky RB, Lim KO, Pfefferbaum A (1991): Brain size in schizophrenia (letter). Arch Gen Psychiatry 48:179-180.
63. Zipursky RB, Lim KO, Sullivan EV, Brown BW, Pfefferbaum A (1992): Widespread cerebral gray matter volume deficits in schizophrenia. Arch Gen Psychiatry 49:195-205.