Antiobesity effect of YM348, a novel 5-HT2C receptor agonist, in Zucker rats

Brain Research

Volumn 1011, Issue 2, 2004, Pages 221-227

  Hayashi, Aska ^a   Sonoda, Rie ^a   Kimura, Yasuharu ^a   Takasu, Toshiyuki ^a   Suzuki, Masanori ^a   Sasamata, Masao ^a   Miyata, Keiji ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

(S) 2 (7 Ethyl 1H furo 2, 3 g indazol 1 yl) 1 methylethylamine (YM348); 5 HT2C receptor; Body temperature; Body weight; Calorie expenditure; Food intake; Monoamines and behavior; Neural basis of behavior

Indexed keywords

2 (7 ETHYL 1H FURO[2,3 G]INDAZOL 1 YL) 1 METHYLETHYLAMINE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; ANTIOBESITY AGENT; ETHYLAMINE; SEROTONIN 2C AGONIST; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; UNCLASSIFIED DRUG; YM 348;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY TEMPERATURE; BODY WEIGHT; CALORIE; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; DRUG INFUSION; DRUG INHIBITION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; ENERGY EXPENDITURE; FOOD INTAKE; MALE; NONHUMAN; OBESITY; PRIORITY JOURNAL; RAT; THERMOGENESIS; WEIGHT GAIN; WEIGHT REDUCTION;

AMINOPYRIDINES; ANIMALS; ANTI-OBESITY AGENTS; BLOOD GLUCOSE; BODY TEMPERATURE; BODY WEIGHT; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION ROUTES; DRUG ADMINISTRATION SCHEDULE; DRUG INTERACTIONS; EATING; ENERGY INTAKE; INDAZOLES; INDOLES; INSULIN; LIPIDS; MALE; OBESITY; RATS; RATS, ZUCKER; RECEPTOR, SEROTONIN, 5-HT2C; SEROTONIN ANTAGONISTS; TIME FACTORS; WEIGHT GAIN;

EID: 2442421711     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.03.032     Document Type: Article

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