Pharmacological profile of YM348, a novel, potent and orally active 5-HT2C receptor agonist

European Journal of Pharmacology

Volumn 483, Issue 1, 2004, Pages 37-43

  Kimura, Yasuharu ^a   Hatanaka, Ken Ichi ^a   Naitou, Yuki ^a   Maeno, Kyoichi ^a   Shimada, Itsuro ^a   Koakutsu, Akiko ^a   Wanibuchi, Fumikazu ^a   Yamaguchi, Tokio ^a  

^a ASTELLAS PHARMA INC   (Japan)

Author keywords

5 HT (5 hydroxytryptamine, serotonin); 5 HT2C receptor; Hypolocomotion; mCPP (m chlorophenylpiperazine); MDL100907; Penile erection; Ro60 0175; RS 127445; SB242084

Indexed keywords

(3 CHLOROPHENYL)PIPERAZINE; 2 (6 CHLORO 5 FLUORO 1 INDOLYL) 1 METHYLETHYLAMINE; 2 (7 ETHYL 1H FURO[2,3 G]INDAZOL 1 YL) 1 METHYLETHYLAMINE; 2 AMINO 4 (4 FLUORONAPHTH 1 YL) 6 ISOPROPYLPYRIMIDINE; 6 CHLORO 5 METHYL 1 [[2 [(2 METHYL 3 PYRIDYL)OXY] 5 PYRIDYL]CARBAMOYL]INDOLINE; ALPHA (2,3 DIMETHOXYPHENYL) 1 [2 (4 FLUOROPHENYL)ETHYL] 4 PIPERIDINEMETHANOL; RS 127445; SEROTONIN 2 ANTAGONIST; SEROTONIN 2 RECEPTOR; SEROTONIN 2A ANTAGONIST; SEROTONIN 2B RECEPTOR; SEROTONIN 2C AGONIST; SEROTONIN 2C ANTAGONIST; SEROTONIN 2C RECEPTOR; UNCLASSIFIED DRUG; YM 348;

ANIMAL EXPERIMENT; ARTICLE; BINDING AFFINITY; BLOOD PRESSURE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG MECHANISM; DRUG POTENCY; DRUG RECEPTOR BINDING; DRUG SELECTIVITY; INHIBITION KINETICS; LOCOMOTION; MALE; NONHUMAN; PENIS ERECTION; PRIORITY JOURNAL; PROTEIN FAMILY; RAT;

EID: 0347987923     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2003.10.004     Document Type: Article

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