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Bioorganic and Medicinal Chemistry Letters

Volumn 15, Issue 20, 2005, Pages 4628-4631

9H-Xanthene-9-carboxylic acid [1,2,4]oxadiazol-3-yl- and (2H-tetrazol-5-yl)-amides as potent, orally available mGlu1 receptor enhancers

(6) Vieira, Eric a Huwyler, Jörg a Jolidon, Synèse a Knoflach, Frédéric a Mutel, Vincent b Wichmann, Jürgen a

a F HOFFMANN LA ROCHE LTD (Switzerland)

b ADDEX PHARMACEUTICALS (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,4 OXADIAZOLE DERIVATIVE; 9H XANTHENE 9 CARBONYLCARBAMIC ACID BUTYL ESTER; AMIDE; CALCIUM; DIPHENYLACETYLCARBAMIC ACID ETHYL ESTER; METABOTROPIC RECEPTOR 1; METABOTROPIC RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ALLOSTERISM; CALCIUM CELL LEVEL; CONFERENCE PAPER; DECARBOXYLATION; DRUG BINDING SITE; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG BRAIN LEVEL; DRUG DESIGN; DRUG DISTRIBUTION; DRUG POTENCY; DRUG SCREENING; DRUG SYNTHESIS; EMBRYO; HUMAN; HUMAN CELL; HYDROLYSIS; PHYSIOLOGY; PLASMA CLEARANCE; STRUCTURE ACTIVITY RELATION;

ALLOSTERIC REGULATION; ANIMALS; EXCITATORY AMINO ACID AGONISTS; OXADIAZOLES; RATS; RECEPTORS, METABOTROPIC GLUTAMATE; SPECTROMETRY, FLUORESCENCE; TETRAZOLES;

EID: 24344475655 PISSN: 0960894X EISSN: None Source Type: Journal
DOI: 10.1016/j.bmcl.2005.05.135 Document Type: Conference Paper

Times cited : (88)

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