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Volumn 205, Issue 1, 2005, Pages 10-18

HER-2: A biomarker at the crossroads of breast cancer immunotherapy and molecular medicine

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; CANCER VACCINE; CD45RO ANTIGEN; CD56 ANTIGEN; CD68 ANTIGEN; CYCLOPHOSPHAMIDE; DNA VACCINE; DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLT3 LIGAND; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; ONCOPROTEIN; PACLITAXEL; PROTEIN TYROSINE KINASE; TRASTUZUMAB; UVOMORULIN;

EID: 24344474832     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20387     Document Type: Review
Times cited : (30)

References (81)
  • 6
    • 24344439937 scopus 로고    scopus 로고
    • Trastuzumab in combination with chemotherapy
    • Burstein HJ. 2004. Trastuzumab in combination with chemotherapy. Breast Cancer Res Treat 2003:869-872.
    • (2004) Breast Cancer Res Treat , vol.2003 , pp. 869-872
    • Burstein, H.J.1
  • 10
    • 0345493645 scopus 로고    scopus 로고
    • Targeting HER-2/neu for active-specific immunotherapy in a mouse model of spontaneous breast cancer
    • Cefai D, Morrison BW, Sckell A, Favre L, Balli M, Leunig M, Gimmi CD. 1999. Targeting HER-2/neu for active-specific immunotherapy in a mouse model of spontaneous breast cancer. Int J Cancer 83:393-400.
    • (1999) Int J Cancer , vol.83 , pp. 393-400
    • Cefai, D.1    Morrison, B.W.2    Sckell, A.3    Favre, L.4    Balli, M.5    Leunig, M.6    Gimmi, C.D.7
  • 11
    • 0034076307 scopus 로고    scopus 로고
    • Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
    • Clynes RA, Towers TL, Presta LG, Ravetch JV. 2000. Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets. Nat Med 6:443-446.
    • (2000) Nat Med , vol.6 , pp. 443-446
    • Clynes, R.A.1    Towers, T.L.2    Presta, L.G.3    Ravetch, J.V.4
  • 12
    • 0032850677 scopus 로고    scopus 로고
    • Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease
    • Cobleigh MA, Vogel CL, Tripathy D, Robert NJ, Scholl S, Fehrenbacher L, Wolter JM, Paton V, Shak S, Lieberman G, Slamon DJ. 1999. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. J Clin Oncol 17: 2639-2648.
    • (1999) J Clin Oncol , vol.17 , pp. 2639-2648
    • Cobleigh, M.A.1    Vogel, C.L.2    Tripathy, D.3    Robert, N.J.4    Scholl, S.5    Fehrenbacher, L.6    Wolter, J.M.7    Paton, V.8    Shak, S.9    Lieberman, G.10    Slamon, D.J.11
  • 13
    • 0033559210 scopus 로고    scopus 로고
    • Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells
    • Codony-Servat J, Albanell J, Lopez-Talavera JC, Arribas J, Baselga J. 1999. Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells. Cancer Res 59:1196-1201.
    • (1999) Cancer Res , vol.59 , pp. 1196-1201
    • Codony-Servat, J.1    Albanell, J.2    Lopez-Talavera, J.C.3    Arribas, J.4    Baselga, J.5
  • 16
    • 12844271532 scopus 로고    scopus 로고
    • Conformational HER-2/neu B-cell epitope peptide vaccine designed to incorporate two native disulfide bonds enhances tumor cell binding and antitumor activities
    • Dakappagari NK, Lute KD, Rawale S, Steele JT, Allen SD, Phillips G, Reilly RT, Kaumaya PT. 2005. Conformational HER-2/neu B-cell epitope peptide vaccine designed to incorporate two native disulfide bonds enhances tumor cell binding and antitumor activities. J Biol Chem 280:54-63.
    • (2005) J Biol Chem , vol.280 , pp. 54-63
    • Dakappagari, N.K.1    Lute, K.D.2    Rawale, S.3    Steele, J.T.4    Allen, S.D.5    Phillips, G.6    Reilly, R.T.7    Kaumaya, P.T.8
  • 17
    • 0037471398 scopus 로고    scopus 로고
    • Protein vaccination with the HER2/neu extracellular domain plus anti-HER2/neu antibody-cytokine fusion proteins induces a protective anti-HER2/neu immune response in mice
    • Dela Cruz JS, Lau SY, Ramirez EM, De Giovanni C, Forni G, Morrison SL, Penichet ML. 2003. Protein vaccination with the HER2/neu extracellular domain plus anti-HER2/neu antibody-cytokine fusion proteins induces a protective anti-HER2/neu immune response in mice. Vaccine 21:1317-1326.
    • (2003) Vaccine , vol.21 , pp. 1317-1326
    • Dela Cruz, J.S.1    Lau, S.Y.2    Ramirez, E.M.3    De Giovanni, C.4    Forni, G.5    Morrison, S.L.6    Penichet, M.L.7
  • 19
    • 0030657467 scopus 로고    scopus 로고
    • High titer HER-2/neu protein specific antibody immunity can be detected in patients with early stage breast cancer
    • Disis ML, Pupa SM, Gralow JR, Dittadi R, Ménard S, Cheever MA. 1997. High titer HER-2/neu protein specific antibody immunity can be detected in patients with early stage breast cancer. J Clin Oncol 15:3363-3367.
    • (1997) J Clin Oncol , vol.15 , pp. 3363-3367
    • Disis, M.L.1    Pupa, S.M.2    Gralow, J.R.3    Dittadi, R.4    Ménard, S.5    Cheever, M.A.6
  • 20
    • 0037089223 scopus 로고    scopus 로고
    • Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu-overexpressing cancers
    • Disis ML, Rinn K, Knutson KL, Davis D, Caron D, dela RC, Schiffman K. 2002. Flt3 ligand as a vaccine adjuvant in association with HER-2/neu peptide-based vaccines in patients with HER-2/neu-overexpressing cancers. Blood 99:2845-2850.
    • (2002) Blood , vol.99 , pp. 2845-2850
    • Disis, M.L.1    Rinn, K.2    Knutson, K.L.3    Davis, D.4    Caron, D.5    Dela, R.C.6    Schiffman, K.7
  • 21
    • 0032537396 scopus 로고    scopus 로고
    • Tamoxifen for early breast cancer: An overview of the randomised trials
    • Early Breast Cancer Trialists' Collaborative Group. 1998. Tamoxifen for early breast cancer: An overview of the randomised trials. Lancet 351:1451-1467.
    • (1998) Lancet , vol.351 , pp. 1451-1467
  • 22
    • 0037791709 scopus 로고    scopus 로고
    • Activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs) by human dendritic cells infected with an attenuated influenza A virus expressing a CTL epitope derived from the HER-2/neu proto-oncogene
    • Efferson CL, Schickli J, Ko BK, Kawano K, Mouzi S, Palese P, Garcia-Sastre A, Ioannides CG. 2003. Activation of tumor antigen-specific cytotoxic T lymphocytes (CTLs) by human dendritic cells infected with an attenuated influenza A virus expressing a CTL epitope derived from the HER-2/neu proto-oncogene. J Virol 77:7411-7424.
    • (2003) J Virol , vol.77 , pp. 7411-7424
    • Efferson, C.L.1    Schickli, J.2    Ko, B.K.3    Kawano, K.4    Mouzi, S.5    Palese, P.6    Garcia-Sastre, A.7    Ioannides, C.G.8
  • 24
    • 0141720783 scopus 로고    scopus 로고
    • Cancer vaccines: Between the idea and the reality
    • Finn OJ. 2003. Cancer vaccines: Between the idea and the reality. Nat Rev Immunol 3:630-641.
    • (2003) Nat Rev Immunol , vol.3 , pp. 630-641
    • Finn, O.J.1
  • 27
    • 0036894558 scopus 로고    scopus 로고
    • Disruption of cell-cell adhesion enhances antibody-dependent cellular cytotoxicity: Implications for antibody-based therapeutics of cancer
    • Green SK, Karlsson MC, Ravetch JV, Kerbel RS. 2002. Disruption of cell-cell adhesion enhances antibody-dependent cellular cytotoxicity: Implications for antibody-based therapeutics of cancer. Cancer Res 62:6891-6900.
    • (2002) Cancer Res , vol.62 , pp. 6891-6900
    • Green, S.K.1    Karlsson, M.C.2    Ravetch, J.V.3    Kerbel, R.S.4
  • 30
    • 0028912598 scopus 로고
    • Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake
    • Hurwitz E, Stancovski I, Sela M, Yarden Y. 1995. Suppression and promotion of tumor growth by monoclonal antibodies to ErbB-2 differentially correlate with cellular uptake. Proc Natl Acad Sci USA 92:3353-3357.
    • (1995) Proc Natl Acad Sci USA , vol.92 , pp. 3353-3357
    • Hurwitz, E.1    Stancovski, I.2    Sela, M.3    Yarden, Y.4
  • 31
    • 0027370248 scopus 로고
    • Cytotoxic T cells isolated from ovarian malignant ascites recognize a peptide derived from the HER-2/neu proto-oncogene
    • Ioannides CG, Fisk B, Fan D, Biddison WE, Wharton JT, O'Brian CA. 1993. Cytotoxic T cells isolated from ovarian malignant ascites recognize a peptide derived from the HER-2/neu proto-oncogene. Cell Immunol 151:225-234.
    • (1993) Cell Immunol , vol.151 , pp. 225-234
    • Ioannides, C.G.1    Fisk, B.2    Fan, D.3    Biddison, W.E.4    Wharton, J.T.5    O'Brian, C.A.6
  • 32
    • 0037149539 scopus 로고    scopus 로고
    • Tumour biology: Herceptin acts as an anti-angiogenic cocktail
    • Izumi Y, Xu L, di Tomaso E, Fukumura D, Jain RK. 2002. Tumour biology: Herceptin acts as an anti-angiogenic cocktail. Nature 416:279-280.
    • (2002) Nature , vol.416 , pp. 279-280
    • Izumi, Y.1    Xu, L.2    Di Tomaso, E.3    Fukumura, D.4    Jain, R.K.5
  • 33
    • 0034234854 scopus 로고    scopus 로고
    • Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2
    • Klapper LN, Waterman H, Sela M, Yarden Y. 2000. Tumor-inhibitory antibodies to HER-2/ErbB-2 may act by recruiting c-Cbl and enhancing ubiquitination of HER-2. Cancer Res 60:3384-3388.
    • (2000) Cancer Res , vol.60 , pp. 3384-3388
    • Klapper, L.N.1    Waterman, H.2    Sela, M.3    Yarden, Y.4
  • 34
    • 0035113705 scopus 로고    scopus 로고
    • Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients
    • Knutson KL, Schiffman K, Disis ML. 2001. Immunization with a HER-2/neu helper peptide vaccine generates HER-2/neu CD8 T-cell immunity in cancer patients. J Clin Invest 107:477-484.
    • (2001) J Clin Invest , vol.107 , pp. 477-484
    • Knutson, K.L.1    Schiffman, K.2    Disis, M.L.3
  • 36
    • 1842426004 scopus 로고    scopus 로고
    • Trastuzumab (Herceptin) enhances class I-restricted antigen presentation recognized by HER-2/neu-specific T cytotoxic lymphocytes
    • Kono K, Sato E, Naganuma H, Takahashi A, Mimura K, Nukui H, Fujii H. 2004. Trastuzumab (Herceptin) enhances class I-restricted antigen presentation recognized by HER-2/neu-specific T cytotoxic lymphocytes. Clin Cancer Res 10: 2538-2544.
    • (2004) Clin Cancer Res , vol.10 , pp. 2538-2544
    • Kono, K.1    Sato, E.2    Naganuma, H.3    Takahashi, A.4    Mimura, K.5    Nukui, H.6    Fujii, H.7
  • 37
    • 0037299714 scopus 로고    scopus 로고
    • Recombinant toxins for the treatment of cancer
    • Kreitman RJ. 2003. Recombinant toxins for the treatment of cancer. Curr Opin Mol Ther 5:44-51.
    • (2003) Curr Opin Mol Ther , vol.5 , pp. 44-51
    • Kreitman, R.J.1
  • 39
    • 0028884413 scopus 로고
    • Requirement for neuregulin receptor erbB2 in neural and cardiac development
    • Lee K-F, Simon H, Chen H, Bates B, Hung M-C, Hauser C. 1995. Requirement for neuregulin receptor erbB2 in neural and cardiac development. Nature 378: 394-398.
    • (1995) Nature , vol.378 , pp. 394-398
    • Lee, K.-F.1    Simon, H.2    Chen, H.3    Bates, B.4    Hung, M.-C.5    Hauser, C.6
  • 40
    • 0028928063 scopus 로고
    • MCF-7 breast cancer cells overexpressing transfected c-erbB-2 have an in vitro growth advantage in estrogen-depleted conditions and reduced estrogen-dependence and tamoxifen-sensitivity in vivo
    • Liu Y, El-Ashry D, Chen D, Ding IYF, Kern FG. 1995. MCF-7 breast cancer cells overexpressing transfected c-erbB-2 have an in vitro growth advantage in estrogen-depleted conditions and reduced estrogen-dependence and tamoxifen-sensitivity in vivo. Breast Cancer Res Treat 34:97-117.
    • (1995) Breast Cancer Res Treat , vol.34 , pp. 97-117
    • Liu, Y.1    El-Ashry, D.2    Chen, D.3    Ding, I.Y.F.4    Kern, F.G.5
  • 41
    • 0036047820 scopus 로고    scopus 로고
    • Antitumor vaccines: Is it possible to prevent a tumor?
    • Lollini PL, Forni G. 2002. Antitumor vaccines: Is it possible to prevent a tumor? Cancer Immunol Immunother 51:409-416.
    • (2002) Cancer Immunol Immunother , vol.51 , pp. 409-416
    • Lollini, P.L.1    Forni, G.2
  • 42
    • 0141992909 scopus 로고    scopus 로고
    • HSP110-HER2/neu chaperone complex vaccine induces protective immunity against spontaneous mammary tumors in HER-2/neu transgenic mice
    • Manjili MH, Wang XY, Chen X, Martin T, Repasky EA, Henderson R, Subjeck JR. 2003. HSP110-HER2/neu chaperone complex vaccine induces protective immunity against spontaneous mammary tumors in HER-2/neu transgenic mice. J Immunol 171:4054-4061.
    • (2003) J Immunol , vol.171 , pp. 4054-4061
    • Manjili, M.H.1    Wang, X.Y.2    Chen, X.3    Martin, T.4    Repasky, E.A.5    Henderson, R.6    Subjeck, J.R.7
  • 43
    • 0028827104 scopus 로고
    • Multiple essential functions of neuregulin in development
    • Meyer D, Birchmeier C. 1995. Multiple essential functions of neuregulin in development. Nature 378:386-390.
    • (1995) Nature , vol.378 , pp. 386-390
    • Meyer, D.1    Birchmeier, C.2
  • 45
    • 0034283019 scopus 로고    scopus 로고
    • Natural T-cell response against MHC class I epitopes of epithelial cell adhesion molecule, her-2/neu, and carcinoembryonic antigen in patients with colorectal cancer
    • Nagorsen D, Keilholz U, Rivoltini L, Schmittel A, Letsch A, Asemissen AM, Berger G, Buhr HJ, Thiel E, Scheibenbogen C. 2000. Natural T-cell response against MHC class I epitopes of epithelial cell adhesion molecule, her-2/neu, and carcinoembryonic antigen in patients with colorectal cancer. Cancer Res 60:4850-4854.
    • (2000) Cancer Res , vol.60 , pp. 4850-4854
    • Nagorsen, D.1    Keilholz, U.2    Rivoltini, L.3    Schmittel, A.4    Letsch, A.5    Asemissen, A.M.6    Berger, G.7    Buhr, H.J.8    Thiel, E.9    Scheibenbogen, C.10
  • 46
    • 1942474587 scopus 로고    scopus 로고
    • The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells
    • Nahta R, Hung MC, Esteva FJ. 2004. The HER-2-targeting antibodies trastuzumab and pertuzumab synergistically inhibit the survival of breast cancer cells. Cancer Res 64:2343-2346.
    • (2004) Cancer Res , vol.64 , pp. 2343-2346
    • Nahta, R.1    Hung, M.C.2    Esteva, F.J.3
  • 49
    • 1542321226 scopus 로고    scopus 로고
    • Animal models of tumor immunity, immunotherapy and cancer vaccines
    • Ostrand-Rosenberg S. 2004. Animal models of tumor immunity, immunotherapy and cancer vaccines. Curr Opin Immunol 16:143-150.
    • (2004) Curr Opin Immunol , vol.16 , pp. 143-150
    • Ostrand-Rosenberg, S.1
  • 50
    • 9244219598 scopus 로고    scopus 로고
    • Breast cancer - Loss of PTEN predicts resistance to treatment
    • Pandolfi PP. 2004. Breast cancer-loss of PTEN predicts resistance to treatment. N Engl J Med 351:2337-2338.
    • (2004) N Engl J Med , vol.351 , pp. 2337-2338
    • Pandolfi, P.P.1
  • 51
    • 0036791488 scopus 로고    scopus 로고
    • IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells
    • Parihar R, Dierksheide J, Hu Y, Carson WE. 2002. IL-12 enhances the natural killer cell cytokine response to Ab-coated tumor cells. J Clin Invest 110:983-992.
    • (2002) J Clin Invest , vol.110 , pp. 983-992
    • Parihar, R.1    Dierksheide, J.2    Hu, Y.3    Carson, W.E.4
  • 52
    • 0033779252 scopus 로고    scopus 로고
    • Biological rationale for HER2/neu (c-erbB2) as a target for monoclonal antibody therapy
    • Pegram M, Slamon D. 2000. Biological rationale for HER2/neu (c-erbB2) as a target for monoclonal antibody therapy. Semin Oncol 27:13-19.
    • (2000) Semin Oncol , vol.27 , pp. 13-19
    • Pegram, M.1    Slamon, D.2
  • 54
    • 0035885078 scopus 로고    scopus 로고
    • Complementary antitumor immunity induced by plasmid DNA encoding secreted and cytoplasmic human ErbB-2
    • Piechocki MP, Pilon SA, Wei WZ. 2001. Complementary antitumor immunity induced by plasmid DNA encoding secreted and cytoplasmic human ErbB-2. J Immunol 167:3367-3374.
    • (2001) J Immunol , vol.167 , pp. 3367-3374
    • Piechocki, M.P.1    Pilon, S.A.2    Wei, W.Z.3
  • 56
    • 0025359146 scopus 로고
    • Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues
    • Press MF, Cordon-Cardo C, Slamon DJ. 1990. Expression of the HER-2/neu proto-oncogene in normal human adult and fetal tissues. Oncogene 5:953-962.
    • (1990) Oncogene , vol.5 , pp. 953-962
    • Press, M.F.1    Cordon-Cardo, C.2    Slamon, D.J.3
  • 57
    • 0027146671 scopus 로고
    • Antibody response against the c-erbB-2 oncoprotein in breast carcinoma patients
    • Pupa SM, Ménard S, Andreola S, Colnaghi MI. 1993. Antibody response against the c-erbB-2 oncoprotein in breast carcinoma patients. Cancer Res 53:5864-5866.
    • (1993) Cancer Res , vol.53 , pp. 5864-5866
    • Pupa, S.M.1    Ménard, S.2    Andreola, S.3    Colnaghi, M.I.4
  • 62
    • 0141891468 scopus 로고    scopus 로고
    • Evaluation of pre-existent immunity in patients with primary breast cancer: Molecular and cellular assays to quantify antigen-specific T lymphocytes in peripheral blood mononuclear cells
    • Rentzsch C, Kayser S, Stumm S, Watermann I, Walter S, Stevanovic S, Wallwiener D, Guckel B. 2003. Evaluation of pre-existent immunity in patients with primary breast cancer: Molecular and cellular assays to quantify antigen-specific T lymphocytes in peripheral blood mononuclear cells. Clin Cancer Res 9:4376-4386.
    • (2003) Clin Cancer Res , vol.9 , pp. 4376-4386
    • Rentzsch, C.1    Kayser, S.2    Stumm, S.3    Watermann, I.4    Walter, S.5    Stevanovic, S.6    Wallwiener, D.7    Guckel, B.8
  • 64
    • 7444247986 scopus 로고    scopus 로고
    • Vaccination by genetically modified dendritic cells expressing a truncated neu oncogene prevents development of breast cancer in transgenic mice
    • Sakai Y, Morrison BJ, Burke JD, Park JM, Terabe M, Janik JE, Forni G, Berzofsky JA, Morris JC. 2004. Vaccination by genetically modified dendritic cells expressing a truncated neu oncogene prevents development of breast cancer in transgenic mice. Cancer Res 64:8022-8028.
    • (2004) Cancer Res , vol.64 , pp. 8022-8028
    • Sakai, Y.1    Morrison, B.J.2    Burke, J.D.3    Park, J.M.4    Terabe, M.5    Janik, J.E.6    Forni, G.7    Berzofsky, J.A.8    Morris, J.C.9
  • 67
    • 0032472938 scopus 로고    scopus 로고
    • A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor
    • Sibilia M, Steinbach JP, Stingl L, Aguzzi A, Wagner EF. 1998. A strain-independent postnatal neurodegeneration in mice lacking the EGF receptor. EMBO J 17:719-731.
    • (1998) EMBO J , vol.17 , pp. 719-731
    • Sibilia, M.1    Steinbach, J.P.2    Stingl, L.3    Aguzzi, A.4    Wagner, E.F.5
  • 71
    • 0036284422 scopus 로고    scopus 로고
    • Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo
    • Spiridon CI, Ghetie MA, Uhr J, Marches R, Li JL, Shen GL, Vitetta ES. 2002. Targeting multiple Her-2 epitopes with monoclonal antibodies results in improved antigrowth activity of a human breast cancer cell line in vitro and in vivo. Clin Cancer Res 8:1720-1730.
    • (2002) Clin Cancer Res , vol.8 , pp. 1720-1730
    • Spiridon, C.I.1    Ghetie, M.A.2    Uhr, J.3    Marches, R.4    Li, J.L.5    Shen, G.L.6    Vitetta, E.S.7
  • 73
    • 0035889703 scopus 로고    scopus 로고
    • Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes
    • Tanaka Y, Amos KD, Joo HG, Eberlein TJ, Goedegebuure PS. 2001. Modification of the HER2/NEU-derived tumor antigen GP2 improves induction of GP2-reactive cytotoxic T lymphocytes. Int J Cancer 94:540-544.
    • (2001) Int J Cancer , vol.94 , pp. 540-544
    • Tanaka, Y.1    Amos, K.D.2    Joo, H.G.3    Eberlein, T.J.4    Goedegebuure, P.S.5
  • 74
    • 0037309211 scopus 로고    scopus 로고
    • Induction of antigen-specific CTL by recombinant HIV trans-activating fusion protein-pulsed human monocyte-derived dendritic cells
    • Tanaka Y, Dowdy SF, Linehan DC, Eberlein TJ, Goedegebuure PS. 2003. Induction of antigen-specific CTL by recombinant HIV trans-activating fusion protein-pulsed human monocyte-derived dendritic cells. J Immunol 170:1291-1298.
    • (2003) J Immunol , vol.170 , pp. 1291-1298
    • Tanaka, Y.1    Dowdy, S.F.2    Linehan, D.C.3    Eberlein, T.J.4    Goedegebuure, P.S.5
  • 75
    • 0027240137 scopus 로고
    • Masking of HLA class I molecules expressed on K-562 target cells can restore their susceptibility to NK cell cytolysis
    • Toth J, Kubes M. 1993. Masking of HLA class I molecules expressed on K-562 target cells can restore their susceptibility to NK cell cytolysis. Immunobiology 188:134-144.
    • (1993) Immunobiology , vol.188 , pp. 134-144
    • Toth, J.1    Kubes, M.2
  • 76
    • 0036649794 scopus 로고    scopus 로고
    • Immune changes in patients with advanced breast cancer undergoing chemotherapy with taxanes
    • Tsavaris N, Kosmas C, Vadiaka M, Kanelopoulos P, Boulamatsis D. 2002. Immune changes in patients with advanced breast cancer undergoing chemotherapy with taxanes. Br J Cancer 87:21-27.
    • (2002) Br J Cancer , vol.87 , pp. 21-27
    • Tsavaris, N.1    Kosmas, C.2    Vadiaka, M.3    Kanelopoulos, P.4    Boulamatsis, D.5
  • 77
    • 0042931259 scopus 로고    scopus 로고
    • Rapid high efficiency sensitization of CD8+ T cells to tumor antigens by dendritic cells leads to enhanced functional avidity and direct tumor recognition through an IL-12-dependent mechanism
    • Xu S, Koski GK, Faries M, Bedrosian I, Mick R, Maeurer M, Cheever MA, Cohen PA, Czerniecki BJ. 2003. Rapid high efficiency sensitization of CD8+ T cells to tumor antigens by dendritic cells leads to enhanced functional avidity and direct tumor recognition through an IL-12-dependent mechanism. J Immunol 171:2251-2261.
    • (2003) J Immunol , vol.171 , pp. 2251-2261
    • Xu, S.1    Koski, G.K.2    Faries, M.3    Bedrosian, I.4    Mick, R.5    Maeurer, M.6    Cheever, M.A.7    Cohen, P.A.8    Czerniecki, B.J.9
  • 78
    • 0037099532 scopus 로고    scopus 로고
    • Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt is required for antibody-mediated effects on p27, cyclin D1, and antitumor action
    • Yakes FM, Chinratanalab W, Ritter CA, King W, Seelig S, Arteaga CL. 2002. Herceptin-induced inhibition of phosphatidylinositol-3 kinase and Akt is required for antibody-mediated effects on p27, cyclin D1, and antitumor action. Cancer Res 62:4132-4141.
    • (2002) Cancer Res , vol.62 , pp. 4132-4141
    • Yakes, F.M.1    Chinratanalab, W.2    Ritter, C.A.3    King, W.4    Seelig, S.5    Arteaga, C.L.6
  • 79
    • 0032213456 scopus 로고    scopus 로고
    • Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptide-specific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors
    • Zaks TZ, Rosenberg SA. 1998. Immunization with a peptide epitope (p369-377) from HER-2/neu leads to peptide-specific cytotoxic T lymphocytes that fail to recognize HER-2/neu+ tumors. Cancer Res 58:4902-4908.
    • (1998) Cancer Res , vol.58 , pp. 4902-4908
    • Zaks, T.Z.1    Rosenberg, S.A.2
  • 80
    • 0030058647 scopus 로고    scopus 로고
    • Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines
    • Zitvogel L, Mayordomo JI, Tjandrawan T, DeLeo AB, Clarke MR, Lofae MT, Storkus WJ. 1996. Therapy of murine tumors with tumor peptide-pulsed dendritic cells: Dependence on T cells, B7 costimulation, and T helper cell 1-associated cytokines. J Exp Med 183:87-97.
    • (1996) J Exp Med , vol.183 , pp. 87-97
    • Zitvogel, L.1    Mayordomo, J.I.2    Tjandrawan, T.3    DeLeo, A.B.4    Clarke, M.R.5    Lofae, M.T.6    Storkus, W.J.7
  • 81
    • 0035424915 scopus 로고    scopus 로고
    • The generation of both T killer and Th cell clones specific for the tumor-associated antigen HER2 using retrovirally transduced dendritic cells
    • zum Buschenfelde CM, Metzger J, Hermann C, Nicklisch N, Peschel C, Bernhard H. 2001. The generation of both T killer and Th cell clones specific for the tumor-associated antigen HER2 using retrovirally transduced dendritic cells. J Immunol 167:1712-1719.
    • (2001) J Immunol , vol.167 , pp. 1712-1719
    • Zum Buschenfelde, C.M.1    Metzger, J.2    Hermann, C.3    Nicklisch, N.4    Peschel, C.5    Bernhard, H.6


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