Extremely low-frequency electromagnetic fields do not affect DNA damage and gene expression profiles of yeast and human lymphocytes

Radiation Research

Volumn 164, Issue 3, 2005, Pages 277-285

  Luceri, Cristina ^a   De Filippo, Carlotta ^a   Giovannelli, Lisa ^a   Blangiardo, Marta ^a   Cavalieri, Duccio ^a   Aglietti, Filippo ^a   Pampaloni, Monica ^a   Andreuccetti, Daniele ^b   Pieri, Lapo ^b   Bambi, Franco ^c   Biggeri, Annibale ^a   Dolara, Piero ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b CNR   (Italy)

^c UNIVERSITY OF FLORENCE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; RNA;

ARTICLE; COMET ASSAY; DNA DAMAGE; DNA MICROARRAY; DNA STRAND BREAKAGE; ELECTROMAGNETIC FIELD; GENE EXPRESSION; HUMAN; HUMAN CELL; LYMPHOCYTE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; YEAST CELL;

BLOOD PROTEINS; CELLS, CULTURED; DNA; DNA DAMAGE; DOSE-RESPONSE RELATIONSHIP, RADIATION; ELECTRICITY; ELECTROMAGNETIC FIELDS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; HUMANS; LYMPHOCYTES; RADIATION DOSAGE; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 24144474640     PISSN: 00337587     EISSN: None     Source Type: Journal    
DOI: 10.1667/RR3426.1     Document Type: Article

References (34)

1. C. Ahlbom, E. Cardis, A. Green, M. Linei, D. Savitz and A. Swerdlow. ICNIRP (International Commission for Non-Ionizing Radiation Protection) Standing Committee on Epidemiology. Review of the epidemiologic literature on EMF and Health. Environ. Health Perspect. 109, 911-933 (2001).
2. A. Ahlbom, N. Day, M. Feychting, E. Roman, J. Skinner, J. Dockerty, M. Linet, M. McBricle, J. Michaelis and P. K. Verkasalo. A pooled analysis of magnetic fields and childhood leukaemia. Br. J. Cancer 83, 692-698 (2000).
3. IARC, Non-ionizing Radiation, part I: Static and Extremely Low Frequency (ELF) Electric anil Magnetic Fields. Monographs on the Evaluation of Carcinogenic Risk to Humans. Vol. 80. International Association for Research on Cancer. Lyon. 2002.
4. A. Lacy-Hulbert, J. C. Metcalfe and R. Hesketh. Bioloaical responses to electromagnetic fields. FASEB J. 12, 395-420 (1998).
5. J. Miyakoshi, K. Kitagawa and H. Takebe. Mutation induction by high-density. 50-Hz magnetic fields in human MeWo cells exposed high-density DNA synthesis phase. Int. J. Radiat. Biol 71, 75-79 (1997).
6. J. L. Phillips, W. Hageren, W. J. Thomas, J. T. Ishida and W. R. Adey. Magnetic field induced changes in specific gene transcription. Biochiin. Biophys. Acta 1132, 140-144 (1992).
7. G. R. Ding, T. Nakahara and J. Miyakoshi. Exposure to power frequency magnetic fields and X-rays induces GAP-43 gene expression in human glioma MO54 cells. Bioelectromagnetics 23, 586-591 (2002).
8. S. V. Tokalov and H. O. Gulzeit. The heat shock-induced cell cycle arrest is attenuated by weak electromagnetic fields. Cell Prolif. 36, 101-111 (2003).
9. J. Zhou, C. Li, G. Yao, H. Chiang and Z. Chang. Gene expression of cytokine receptors in HL60 cells exposed to a 50 Hz magnetic field. Bioelectromagnetics 23, 339-346 (2002).
10. 2+ but not PKA, PKC, ERK, or p38 MAPK. Biochem. Biophys. Res. Commun. 296, 1013-1018 (2002).
11. Y. H. Cho and H. W. Chung. The effect of extremely low frequency electromagnetic fields (ELF-EMF) on the frequency of micronuclei and sister chromatid exchange in human lymphocytes induced by benzo(a)pyrene. Toxicol. Lett. 143, 37-44 (2003).
12. S. Ivancsits, E. Diem, A. Pilger, H. W. Rudiger and O. Jahn. Induction of DNA strand breaks by intermittent exposure to extremely-low-frequency electromagnetic fields in human diploid fibroblasts. Mutat. Rex. 519, 1-13 (2002).
13. H. Lai and N. P. Singh. Magnetic-field-induced DNA strand breaks in brain cells of the rat. Environ. Health Perxpect. 112, 687-694 (2004).
14. B. M. Svedenslal, K. J. Johanson and K. H. Mild. DNA damage induced in brain cells of CBA mice exposed to magnetic fields. In Vivo 13, 551-552 (1999).
15. M. Fedrowitz, J. Westerniann and W. Loscher. Magnetic field exposure increases cell proliferation but docs not affect melatonin levels in the mammary gland of female Sprague Dawley rats. Cancer Res. 62, 1356-1363 (2002).
16. G. Chen, B. L. Upham, W. Sun, C. C. Chang, E. J. Rothwell, K. M. Chen, H. Yamasaki and J. E. Trosko. Effect of electromagnetic field exposure on chemically induced differentiation of friend erythroleukemia cells. Environ. Health Perspect. 108, 967-972 (2000).
17. D. Andreuccetti, M. Bini, A. Ignesti, R. Olmi, S. Priori and R. Vanni. Helmholtz coils for the generation of standard magnetic fields in biological applications. Proceedings of the VII National Congress of the AIFB. Monte Conero. Ancona (Italy), June 1992. Phys. Med. IX (Suppl. 1). 283-285 (1993).
18. L. Giovannelli, V. Pitozzi, J. S. Riolo and P. Dolara. Measurement of DNA breaks and oxidative damage in polymorphonuclear and mononuclear white blood cells: A novel approach using the comet assay. Mutat. Res. 538, 71-80 (2003).
19. A. R. Collins, S. J. Duthie and V. L. Dobson. Direct enzymic detection of endogenous oxidative base damage in human lymphocyte DNA. Carcinogenesis 14 1733-1735 (1993).
20. A. R. Collins, M. Dusinska, C. M. Gedik and R. Stetina. Oxidative damage to DNA: Do we have a reliable biomarker? Environ. Health Perspect. 104 (Suppl. 3), 465-469 (1996).
21. R. Simon, E. Korn and L. McShane. Design and Analysis of DNA Microarray Investigations. Springer-Verlag, New York, 2003.
22. Y. Yang, S. Dudoit, P. Luu, D. Lin, V. Peng, J. Ngai and T. Speed. Normalization for cDNA microarray data: A robust composite method addressing single and multiple slide systematic variation. Nucleic Acids Res. 30, 15 (2002).
23. M. Newton, C. Kendziorski, C. Richmond, F. Blattner and K. Tsui. On differential variability of expression ratios: Improving statistical inference about gene expression changes from microarray data. J. Computational Biol. 8, 37-52 (2001).
24. V. Tusher, R. Tibshirani and G. Chu. Significance analysis of microarray applied to the ionizing radiation response. Proc. Natl. Acad. Sci. USA 98, 5116-5121 (2001).
25. J. D. Storey. The positive false discovery rate: A Bayesian interpretation and the q-value. Ann. Stat. 31, 2013-2035 (2003).
26. I. Lonnstedt and T. Speed. Replicated microarray data. Stat. Sin. 12. 31-46 (2002).
27. S. Chu, J. DeRisi, M. Eisen, J. Mulholland, D. Botstein, P. O. Brown and I. Herskowitz. The transcriptional program of sporulation in budding yeast. Science 282, 699-705 (1998).
28. M. A. Resnick and B. S. Cox. Yeast as an honorary mammal. Mutat. Rex. 451. 1-11 (2000).
29. S. Nakasono, C. Laramee, H. Saiki and K. J. McLeod. Effect of power-frequency magnetic fields on genome-scale gene expression in Saccharomyces cerevisiae. Radiat. Res. 160, 25-37 (2003).
30. E. K. Balcer-Kubiczck, G. H. Harrison, C. C. Davis, M. L. Haas and B. H. Koffman. Expression analysis of human HL60 cells exposed to 60 Hz square- or sine-wave magnetic fields. Radiat. Res. 53, 670-678 (2000).
31. L. A. Coulton, P. A. Harris, A. T. Barker and A. G. Pockley. Effect of 50 Hz electromagnetic fields on the induction of heat-shock protein gene expression in human leukocytes. Radiat. Res. 161, 430-434 (2004).
32. R. Goodman and M. Blank, Insights into electromagnetic interaction mechanisms. J. Cell Physiol. 192, 16-22 (2002).
33. A. P. Gasch, P. T. Spellman, C. M. Kao, O. Carmel-Harel, M. B. Eisen, G. Storz, D. Botstein and P. O. Brown. Genomic expression programs in the response of yeast cells to environmental changes. Mol. Biol. Cell. 11, 4241-4257 (2000).
34. S. Debey, U. Schoenbeck, M. Hellmich, B. S. Gathof, R. Pillai, T. Zander and J. L. Schultze. Comparison of different isolation techniques prior gene expression profiling of blood derived cells: impact on physiological responses, on overall expression and the role of different cell types. Pharmacogenomics J. 4, 193-207 (2004).