-
1
-
-
0030936323
-
PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer
-
Li J, Yen C, Liaw D, Podsypanina K, Bose S, Wang SI, Puc J, Miliaresis C, Rodgers L, McCombie R, Bigner SH, Giovanella BC, Ittmann M, Tycko B, Hibshoosh H, Wigler MH, Parsons R: PTEN, a putative protein tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer. Science 1997;275:1943-1947
-
(1997)
Science
, vol.275
, pp. 1943-1947
-
-
Li, J.1
Yen, C.2
Liaw, D.3
Podsypanina, K.4
Bose, S.5
Wang, S.I.6
Puc, J.7
Miliaresis, C.8
Rodgers, L.9
McCombie, R.10
Bigner, S.H.11
Giovanella, B.C.12
Ittmann, M.13
Tycko, B.14
Hibshoosh, H.15
Wigler, M.H.16
Parsons, R.17
-
2
-
-
0036533982
-
Expression and prognostic significance of PTEN product protein in patients with esophageal squamous cell carcinoma
-
Tachibana M, Shibakita M, Ohno S, Kinugasa S, Yoshimura H, Ueda S, Fujii T, Rahman MA, Dhar DK, Nagasue N: Expression and prognostic significance of PTEN product protein in patients with esophageal squamous cell carcinoma. Cancer 2002;94:1955-1960
-
(2002)
Cancer
, vol.94
, pp. 1955-1960
-
-
Tachibana, M.1
Shibakita, M.2
Ohno, S.3
Kinugasa, S.4
Yoshimura, H.5
Ueda, S.6
Fujii, T.7
Rahman, M.A.8
Dhar, D.K.9
Nagasue, N.10
-
3
-
-
0037089643
-
Loss of PTEN expression is associated with metastatic disease in patients with endometrial carcinoma
-
Salvesen HB, Stefansson I, Kalvenes MB, Das S, Akslen LA: Loss of PTEN expression is associated with metastatic disease in patients with endometrial carcinoma. Cancer 2002; 94:2185-2191
-
(2002)
Cancer
, vol.94
, pp. 2185-2191
-
-
Salvesen, H.B.1
Stefansson, I.2
Kalvenes, M.B.3
Das, S.4
Akslen, L.A.5
-
4
-
-
16544380194
-
Reduced PTEN expression is associated with poor outcome and angiogenesis in invasive ductal carcinoma of the breast
-
Lee JS, Kim HS, Kim YB, Lee MC, Park CS, Min KW: Reduced PTEN expression is associated with poor outcome and angiogenesis in invasive ductal carcinoma of the breast. Appl Immunohistochem Mol Morphol 2004;12:205-210
-
(2004)
Appl Immunohistochem Mol Morphol
, vol.12
, pp. 205-210
-
-
Lee, J.S.1
Kim, H.S.2
Kim, Y.B.3
Lee, M.C.4
Park, C.S.5
Min, K.W.6
-
5
-
-
0242330122
-
Expression of PTEN in renal cell carcinoma and its relation to tumor behavior and growth
-
Lee JS, Kim HS, Kim YB, Lee MC, Park CS: Expression of PTEN in renal cell carcinoma and its relation to tumor behavior and growth. J Surg Oncol 2003;84:166-172
-
(2003)
J Surg Oncol
, vol.84
, pp. 166-172
-
-
Lee, J.S.1
Kim, H.S.2
Kim, Y.B.3
Lee, M.C.4
Park, C.S.5
-
6
-
-
0032126808
-
Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers
-
Maxwell GL, Risinger JI, Tong B, Shaw H, Barrett JC, Berchuck A, Futreal PA: Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers. Gynecol Oncol 1998;70:13-16
-
(1998)
Gynecol Oncol
, vol.70
, pp. 13-16
-
-
Maxwell, G.L.1
Risinger, J.I.2
Tong, B.3
Shaw, H.4
Barrett, J.C.5
Berchuck, A.6
Futreal, P.A.7
-
7
-
-
0032523808
-
Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous ovarian epithelial tumors
-
Obata K, Morland SJ, Watson RH, Hitchcock A, Chenevix-Trench G, Thomas EJ, Campbell IG: Frequent PTEN/MMAC mutations in endometrioid but not serous or mucinous ovarian epithelial tumors. Cancer Res 1998;58:2095-2097
-
(1998)
Cancer Res
, vol.58
, pp. 2095-2097
-
-
Obata, K.1
Morland, S.J.2
Watson, R.H.3
Hitchcock, A.4
Chenevix-Trench, G.5
Thomas, E.J.6
Campbell, I.G.7
-
8
-
-
0031804873
-
Mutation analysis of the putative tumor suppressor PTEN/MMAC1 in human ovarian cancer
-
Yokomizo A, Tindall DJ, Hartmann L, Jenkins RB, Smith DI, Liu W: Mutation analysis of the putative tumor suppressor PTEN/MMAC1 in human ovarian cancer. Int J Oncol 1998; 13:101-105
-
(1998)
Int J Oncol
, vol.13
, pp. 101-105
-
-
Yokomizo, A.1
Tindall, D.J.2
Hartmann, L.3
Jenkins, R.B.4
Smith, D.I.5
Liu, W.6
-
9
-
-
0034650817
-
Allelic imbalance and mutations of the PTEN gene in ovarian cancer
-
Saito M, Okamoto A, Kohno T, Takakura S, Shinozaki H, Isonishi S, Yasuhara T, Yoshimura T, Ohtake Y, Ochiai K, Yokota J, Tanaka T: Allelic imbalance and mutations of the PTEN gene in ovarian cancer. Int J Cancer 2000;85:160-165
-
(2000)
Int J Cancer
, vol.85
, pp. 160-165
-
-
Saito, M.1
Okamoto, A.2
Kohno, T.3
Takakura, S.4
Shinozaki, H.5
Isonishi, S.6
Yasuhara, T.7
Yoshimura, T.8
Ohtake, Y.9
Ochiai, K.10
Yokota, J.11
Tanaka, T.12
-
10
-
-
0034671218
-
Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: Possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary
-
Sato N, Tsunoda H, Nishida M, Morishita Y, Takimoto Y, Kubo T, Noguchi M: Loss of heterozygosity on 10q23.3 and mutation of the tumor suppressor gene PTEN in benign endometrial cyst of the ovary: Possible sequence progression from benign endometrial cyst to endometrioid carcinoma and clear cell carcinoma of the ovary. Cancer Res 2000;60: 7052-7056
-
(2000)
Cancer Res
, vol.60
, pp. 7052-7056
-
-
Sato, N.1
Tsunoda, H.2
Nishida, M.3
Morishita, Y.4
Takimoto, Y.5
Kubo, T.6
Noguchi, M.7
-
11
-
-
0034976644
-
Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas
-
Kurose K, Zhou XP, Araki T, Cannistra SA, Maher ER, Eng C: Frequent loss of PTEN expression is linked to elevated phosphorylated Akt levels, but not associated with p27 and cyclin D1 expression, in primary epithelial ovarian carcinomas. Am J Pathol 2001;158:2097-2106
-
(2001)
Am J Pathol
, vol.158
, pp. 2097-2106
-
-
Kurose, K.1
Zhou, X.P.2
Araki, T.3
Cannistra, S.A.4
Maher, E.R.5
Eng, C.6
-
12
-
-
2642581921
-
Expression of the tumor suppressor gene PTEN is not altered in the progression of ovarian carcinomas and does not correlate with p27Kip1 expression
-
Schondorf T, Hoopmann M, Eversheim B, Valter MM, Becker M, Wappenschmidt B, Gohring UJ, Kubler T, Schmutzler RK, Schafer R: Expression of the tumor suppressor gene PTEN is not altered in the progression of ovarian carcinomas and does not correlate with p27Kip1 expression. Oncol Rep 2003;10:1717-1722
-
(2003)
Oncol Rep
, vol.10
, pp. 1717-1722
-
-
Schondorf, T.1
Hoopmann, M.2
Eversheim, B.3
Valter, M.M.4
Becker, M.5
Wappenschmidt, B.6
Gohring, U.J.7
Kubler, T.8
Schmutzler, R.K.9
Schafer, R.10
-
13
-
-
1842760534
-
Effects of mutation and expression of PTEN gene mRNA on tumorigenesis and progression of epithelial ovarian cancer
-
Chen Y, Zheng H, Yang X, Sun L, Xin Y: Effects of mutation and expression of PTEN gene mRNA on tumorigenesis and progression of epithelial ovarian cancer. Chin Med Sci J 2004;19:25-30
-
(2004)
Chin Med Sci J
, vol.19
, pp. 25-30
-
-
Chen, Y.1
Zheng, H.2
Yang, X.3
Sun, L.4
Xin, Y.5
-
14
-
-
0037353562
-
Time to progression is dependent on the expression of the rumour suppressor PTEN in ovarian cancer patients
-
Schondorf T, Gohring UJ, Roth G, Middel I, Becker M, Moser N, Valter MM, Hoopmann M: Time to progression is dependent on the expression of the rumour suppressor PTEN in ovarian cancer patients. Eur J Clin Invest 2003;33:256-260
-
(2003)
Eur J Clin Invest
, vol.33
, pp. 256-260
-
-
Schondorf, T.1
Gohring, U.J.2
Roth, G.3
Middel, I.4
Becker, M.5
Moser, N.6
Valter, M.M.7
Hoopmann, M.8
-
15
-
-
13044305289
-
PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway
-
Sun H, Lesche R, Li DM, Liliental J, Zhang H, Gao J, Gavrilova N, Mueller B, Liu X, Wu H: PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway. Proc Natl Acad Sci USA 1999;96:6199-6204
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 6199-6204
-
-
Sun, H.1
Lesche, R.2
Li, D.M.3
Liliental, J.4
Zhang, H.5
Gao, J.6
Gavrilova, N.7
Mueller, B.8
Liu, X.9
Wu, H.10
-
16
-
-
0034921007
-
Tumor suppressor PTEN: Modulator of cell signaling, growth, migration and apoptosis
-
Yamada KM, Araki M: Tumor suppressor PTEN: Modulator of cell signaling, growth, migration and apoptosis. J Cell Sci 2001;114:2375-2382
-
(2001)
J Cell Sci
, vol.114
, pp. 2375-2382
-
-
Yamada, K.M.1
Araki, M.2
-
17
-
-
0035217537
-
Loss of PTEN expression as a prognostic marker for tongue cancer
-
Lee JI, Soria JC, Hassan KA, El-Naggar AK, Tang X, Liu DD, Hong WK, Mao L: Loss of PTEN expression as a prognostic marker for tongue cancer. Arch Otolaryngol Head Neck Surg 2001;27:1441-1445
-
(2001)
Arch Otolaryngol Head Neck Surg
, vol.27
, pp. 1441-1445
-
-
Lee, J.I.1
Soria, J.C.2
Hassan, K.A.3
El-Naggar, A.K.4
Tang, X.5
Liu, D.D.6
Hong, W.K.7
Mao, L.8
-
18
-
-
0033403733
-
Balance of cell proliferation and apoptosis in breast carcinogenesis
-
Mommers EC, van Diest PJ, Leonhart AM, Meijer CJ, Baak JP: Balance of cell proliferation and apoptosis in breast carcinogenesis. Breast Cancer Res Treat 1999;58:163-169
-
(1999)
Breast Cancer Res Treat
, vol.58
, pp. 163-169
-
-
Mommers, E.C.1
Van Diest, P.J.2
Leonhart, A.M.3
Meijer, C.J.4
Baak, J.P.5
-
19
-
-
0033572553
-
Growth suppression of human ovarian cancer cells by adenovirus-mediated transfer of the PTEN gene
-
Minaguchi T, Mori T, Kanamori Y, Matsushima M, Yoshikawa H, Taketani Y, Nakamura Y: Growth suppression of human ovarian cancer cells by adenovirus-mediated transfer of the PTEN gene. Cancer Res 1999;59:6063-6067
-
(1999)
Cancer Res
, vol.59
, pp. 6063-6067
-
-
Minaguchi, T.1
Mori, T.2
Kanamori, Y.3
Matsushima, M.4
Yoshikawa, H.5
Taketani, Y.6
Nakamura, Y.7
-
20
-
-
0033987126
-
Histopathologic grading of ovarian carcinoma: A review and proposal
-
Silverberg SG: Histopathologic grading of ovarian carcinoma: A review and proposal. Int J Gynecol Pathol 2000;19:7-15
-
(2000)
Int J Gynecol Pathol
, vol.19
, pp. 7-15
-
-
Silverberg, S.G.1
-
21
-
-
2942696404
-
Epigenetic and genetic alteration of PTEN in cervical neoplasms
-
Cheung TH, Lo KW, Yim SF, Chan LK, Heung MS, Chan CS, Cheung AY, Chung TK, Wong YF: Epigenetic and genetic alteration of PTEN in cervical neoplasms. Gynecol Oncol 2004; 93:621-627
-
(2004)
Gynecol Oncol
, vol.93
, pp. 621-627
-
-
Cheung, T.H.1
Lo, K.W.2
Yim, S.F.3
Chan, L.K.4
Heung, M.S.5
Chan, C.S.6
Cheung, A.Y.7
Chung, T.K.8
Wong, Y.F.9
-
22
-
-
17844362200
-
Genetic and epigenetic alterations of the PTEN gene in soft tissue sarcomas
-
Kawaguchi K, Oda Y, Saito T, Takahira T, Yamamoto H, Tamiya S, Iwamoto Y, Tsuneyoshi M: Genetic and epigenetic alterations of the PTEN gene in soft tissue sarcomas. Hum Pathol 2005;36:357-363
-
(2005)
Hum Pathol
, vol.36
, pp. 357-363
-
-
Kawaguchi, K.1
Oda, Y.2
Saito, T.3
Takahira, T.4
Yamamoto, H.5
Tamiya, S.6
Iwamoto, Y.7
Tsuneyoshi, M.8
-
23
-
-
0030458010
-
Increased apoptosis accompanies neoplastic development in the human colorectum
-
Sinicrope FA, Roddey G, McDonnell TJ, Shen Y, Cleary KR, Stephens LC: Increased apoptosis accompanies neoplastic development in the human colorectum. Clin Cancer Res 1996;2:1999-2006
-
(1996)
Clin Cancer Res
, vol.2
, pp. 1999-2006
-
-
Sinicrope, F.A.1
Roddey, G.2
McDonnell, T.J.3
Shen, Y.4
Cleary, K.R.5
Stephens, L.C.6
-
24
-
-
0033002693
-
Apoptotic activity is increased in parallel with the metaplasia- dysplasia-carcinoma sequence of the bronchial epithelium
-
Tormanen U, Nuorva K, Soini Y, Paakko P: Apoptotic activity is increased in parallel with the metaplasia-dysplasia-carcinoma sequence of the bronchial epithelium. Br J Cancer 1999;79:996-1002
-
(1999)
Br J Cancer
, vol.79
, pp. 996-1002
-
-
Tormanen, U.1
Nuorva, K.2
Soini, Y.3
Paakko, P.4
-
25
-
-
0033846314
-
Apoptosis, proliferation, and angiogenesis in oral tissues: Possible relevance to tumour progression
-
Macluskey M, Chandrachud LM, Pazouki S, Green M, Chisholm DM, Ogden GR, Schor SL, Schor AM: Apoptosis, proliferation, and angiogenesis in oral tissues: Possible relevance to tumour progression. J Pathol 2000;191:368-375
-
(2000)
J Pathol
, vol.191
, pp. 368-375
-
-
Macluskey, M.1
Chandrachud, L.M.2
Pazouki, S.3
Green, M.4
Chisholm, D.M.5
Ogden, G.R.6
Schor, S.L.7
Schor, A.M.8
-
26
-
-
0036235115
-
Angiogenesis, cell proliferation and apoptosis in progression of cervical neoplasia
-
Lee JS, Kim HS, Jung JJ, Lee MC, Park CS: Angiogenesis, cell proliferation and apoptosis in progression of cervical neoplasia. Anal Quant Cytol Histol 2002;24:103-113
-
(2002)
Anal Quant Cytol Histol
, vol.24
, pp. 103-113
-
-
Lee, J.S.1
Kim, H.S.2
Jung, J.J.3
Lee, M.C.4
Park, C.S.5
-
27
-
-
0028905370
-
Ki67 antigen immunostaining (MIB 1 monoclonal antibody) in serous ovarian tumors: Index of proliferative activity with prognostic significance
-
Garzetti GG, Ciavattini A, Goteri G, De Nictolis M, Stramazzotti D, Lucarini G, Biagini G: Ki67 antigen immunostaining (MIB 1 monoclonal antibody) in serous ovarian tumors: Index of proliferative activity with prognostic significance. Gynecol Oncol 1995;56:169-174
-
(1995)
Gynecol Oncol
, vol.56
, pp. 169-174
-
-
Garzetti, G.G.1
Ciavattini, A.2
Goteri, G.3
De Nictolis, M.4
Stramazzotti, D.5
Lucarini, G.6
Biagini, G.7
-
28
-
-
0031904555
-
Clinical significance of alpha-catenin, collagen IV, and Ki-67 expression in epithelial ovarian cancer
-
Anttila M, Kosma VM, Ji H, Wei-Ling X, Puolakka J, Juhola M, Saarikoski S, Syrjanen K: Clinical significance of alpha-catenin, collagen IV, and Ki-67 expression in epithelial ovarian cancer. J Clin Oncol 1998;16:2591-2600
-
(1998)
J Clin Oncol
, vol.16
, pp. 2591-2600
-
-
Anttila, M.1
Kosma, V.M.2
Ji, H.3
Wei-Ling, X.4
Puolakka, J.5
Juhola, M.6
Saarikoski, S.7
Syrjanen, K.8
-
29
-
-
0036245396
-
Apoptosis in ovarian epithelial tumors
-
Preethi TR, Chacko P, Kesari AL, Praseeda I, Chellam VG, Pillai MR: Apoptosis in ovarian epithelial tumors. Pathol Res Pract 2002;198:273-280
-
(2002)
Pathol Res Pract
, vol.198
, pp. 273-280
-
-
Preethi, T.R.1
Chacko, P.2
Kesari, A.L.3
Praseeda, I.4
Chellam, V.G.5
Pillai, M.R.6
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