Neuropeptide Y induces torpor-like hypothermia in Siberian hamsters

Brain Research

Volumn 1055, Issue 1-2, 2005, Pages 83-92

  Paul, Matthew J ^a   Freeman, David A ^b   Jin, Ho Park ^a   Dark, John ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF MEMPHIS   (United States)

Author keywords

Brown adipose tissue; Food intake; Metabolism; Peptide; Thermoregulation

Indexed keywords

NEUROPEPTIDE Y;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; COLD ACCLIMATIZATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DOSE RESPONSE; DRUG EFFECT; FEMALE; FOOD INTAKE; HYPOTHERMIA; INCIDENCE; LABORATORY; NONHUMAN; PHODOPUS; PRIORITY JOURNAL; TIME; TORPOR LIKE HYPOTHERMIA;

ANIMALS; BODY TEMPERATURE; CHI-SQUARE DISTRIBUTION; CIRCADIAN RHYTHM; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; FEMALE; HYPOTHERMIA; INJECTIONS, INTRAVENTRICULAR; MOVEMENT; NEUROPEPTIDE Y; PHODOPUS; TIME FACTORS;

EID: 24044544578     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2005.06.090     Document Type: Article

References (66)

1. R.S. Ahima, and J.S. Flier Leptin Annu. Rev. Physiol. 62 2000 413 437
2. A. Akabayashi, C.T. Zaia, I. Silva, H.J. Chae, and S.F. Leibowitz Neuropeptide Y in the arcuate nucleus is modulated by alterations in glucose utilization Brain Res. 261 1993 343 348
3. F.L. Bai, M. Yamano, Y. Shiotani, P.C. Emson, A.D. Smith, J.F. Powell, and M. Tohyama An arcuate-paraventricular and -dorsomedial hypothalamic neuropeptide Y containing system which lacks noradrenaline in the rat Brain Res. 331 1985 172 175
4. M. Bamshad, C.K. Song, and T.J. Bartness CNS origins of the sympathetic nervous system outflow to brown adipose tissue Am. J. Physiol. 276 1999 R1569 R1578
5. K. Baran, E. Preston, D. Wilks, G.J. Cooney, E.W. Kraegen, and A.K. Sainsbury Chronic central melanocortin-4 receptor antagonism and central neuropeptide-Y infusion in rats produced increased adiposity by divergent pathways Diabetes 51 2002 152 157
6. T.J. Bartness, and G.N. Wade Photoperiodic control of seasonal body weight cycles in hamsters Neurosci. Biobehav. Rev. 9 1985 599 612
7. T.J. Bartness, J.M. Hamilton, G.N. Wade, and B.D. Goldman Regional differences in fat pad responses to short days in Siberian hamsters Am. J. Physiol. 257 1989 R1533 R1540
8. S.C. Benoit, D.J. Clegg, R.J. Seeley, and S.C. Woods Insulin and leptin as adiposity signals Recent Prog. Horm. Res. 59 2004 267 285
9. C.J. Billington, J.E. Briggs, M. Grace, and A.S. Levine Effects of intracerebroventricular injection of neuropeptide Y on energy metabolism Am. J. Physiol. 260 1991 R321 R327
10. C.J. Billington, J.E. Briggs, S. Harker, M. Grace, and A.S. Levine Neuropeptide Y in hypothalamic paraventricular nucleus: a center coordinating energy metabolism Am. J. Physiol. 266 1994 R1765 R1770
11. K.A. Boss-Williams, and T.J. Bartness NPY stimulation of food intake in Siberian hamsters is not photoperiod dependent Physiol. Behav. 59 1996 157 164
12. T. Boswell, R.D. Richardson, M.W. Schwartz, D.A. D'Alessio, S.C. Woods, A.J. Sipols, D.G. Baskin, and G.J. Kenagy NPY and galanin in a hibernator: hypothalamic gene expression and effects of feeding Brain Res. Bull. 32 1993 379 384
13. S.M. Bouali, A. Fournier, S. St-Pierre, and F.B. Jolicoeur Influence of ambient temperature on the effects of NPY on body temperature and food intake Pharmacol. Biochem. Behav. 50 1995 473 475
14. C. Broberger, J. Johansen, C. Johansson, M. Schalling, and T. Hökfelt The neuropeptide Y/agouti gene-related protein (AGRP) brain circuitry in normal, anorectic, and monosodium glutamate-treated mice Proc. Nat. Acad. Sci. U. S. A. 95 1998 15043 15048
15. P.J. Currie, and D.V. Coscina Dissociated feeding and hypothermic effects of neuropeptide Y in the paraventricular and perifornical hypothalamus Peptides 16 1995 599 604
16. J. Dark, and D.R. Miller Metabolic fuel privation in hibernating and awake ground squirrels Physiol. Behav. 63 1998 59 65
17. J. Dark, D.R. Miller, and I. Zucker Reduced glucose availability induces torpor in Siberian hamsters Am. J. Physiol. 267 1994 R496 R501
18. J. Dark, D.R. Miller, P. Licht, and I. Zucker Glucoprivation counteracts effects of testosterone on daily torpor in Siberian hamsters Am. J. Physiol. 270 1996 R398 R403
19. M. Egawa, H. Yoshimatsu, and G.A. Bray Effects of 2-deoxy-d-glucose on sympathetic nerve activity to interscapular brown adipose tissue Am. J. Physiol. 257 1989 R1377 R1385
20. M. Egawa, H. Yoshimatsu, and G.A. Bray Neuropeptide Y suppresses sympathetic activity to interscapular brown adipose tissue in rats Am. J. Physiol. 260 1991 R328 R334
21. D.A. Freeman, D.A. Lewis, A.S. Kauffman, R.S. Blum, and J. Dark Reduced leptin concentrations are permissive for display of torpor Am. J. Physiol. 287 2004 R97 R103
22. N. Freinkel, B.E. Metzger, E. Harris, S. Robinson, and M. Mager The hypothermia of hypoglycemia: studies with 2-deoxy-d-glucose in normal human subjects and mice N. Engl. J. Med. 287 1972 841 845
23. F. Geiser Metabolic rate and body temperature reduction during hibernation and torpor Annu. Rev. Physiol. 66 2004 239 274
24. F. Geiser, G. Kortner, and I. Schmidt Leptin increases energy expenditure of a marsupial by inhibition of daily torpor Am. J. Physiol. 275 1998 R1627 R1632
25. B.D. Goldman, J.M. Darrow, M.J. Duncan, and L. Yogev Photoperiod, reproductive hormones, and winter torpor in three hamster species H.C. Heller X.J. Musacchia L.C.H. Wang Living in the Cold: Physiological and Biochemical Adaptations 1986 Elsevier New York 1 351
26. G. Heldmaier, and A. Buchberger Source of heat during nonshivering thermogenesis in Djungarian hamsters: a dominant role for brown adipose tissue during cold adaptation J. Comp. Physiol., B 156 1985 237 245
27. G. Heldmaier, and T. Ruf Body temperature and metabolic rate during natural hypothermia in endotherms J. Comp. Physiol., B 162 1992 696 706
28. G. Heldmaier, S. Steinlechner, and J. Rafael Nonshivering thermogenesis and cold resistance during seasonal acclimatization in the Djungarian hamster J. Comp. Physiol., B 149 1982 1 9
29. G. Heldmaier, H. Boeckler, A. Buchberger, S. Klaus, S. Puchalski, S. Steinlechner, and H. Weisinger Seasonal variation in thermogenesis H.C. Heller X.J. Musacchia L.C.H. Wang Living in the Cold: Physiological and Biochemical Adaptations 1986 Elsevier New York 361 371
30. G. Heldmaier, M. Klingenspor, M. Werneyer, B.J. Lampi, S.P.J. Brooks, and K.B. Storey Metabolic adjustments during daily torpor in the Djungarian hamster Am. J. Physiol. 276 1999 E896 E906
31. J.J. Hildebrand, D. de Wied, and A.R. Adan Neuropeptides, food intake and body weight regulation: a hypothalamic focus Peptides 23 2002 2283 2306
32. K. Hoffmann Influence of photoperiod and melatonin on testis size, body-weight, and pelage colour in Djungarian hamster (Phodopus sungorus) J. Comp. Physiol. 85 1978 267 282
33. J.W. Hudson Shallow, daily torpor: a thermoregulatory adaptation L.C.H. Wang J. Hudson Strategies in the Cold 1978 Academic Press New York 67 108
34. F.B. Jolicoeur, F.-N. Michaud, R. Rivest, D. Menard, D. Gaundin, A. Fournier, and S. St.-Pierre Neurobehavioral profile of neuropeptide Y Brain Res. Bull. 26 1991 265 268
35. F.B. Jolicoeur, S.M. Bouali, A. Fournier, and S. St. -Pierre Mapping of hypothalamic sites involved in the effects of NPY on body temperature and food intake Brain Res. Bull. 36 1995 125 129
36. S.P. Kalra, M.G. Dube, S. Pu, B. Xu, T.L. Horvath, and P.S. Kalra Interacting appetite-regulating pathways in the hypothalamic regulation of body weight Endocr. Rev. 20 1999 68 100
37. A.S. Kauffman, A. Cabrera, and I. Zucker Torpor characteristics and energy requirements of furless Siberian hamsters Physiol. Biochem. Zool. 74 2001 876 884
38. A.C. Keene, J.E. Jones, G.N. Wade, and E.S. Corp Forebrain sites of NPY action on estrous behavior in Syrian hamsters Physiol. Behav. 78 2003 711 716
39. S. Klaus, H. Munzberg, C. Truloff, and G. Heldmaier Physiology of transgenic mice with brown fat ablation: obesity is due to lowered body temperature Am. J. Physiol. 274 1998 R287 R293
40. C.M. Kotz, J.E. Briggs, M.K. Grace, A.S. Levine, and C.J. Billington Divergence of the feeding and thermogenic pathways influenced by NPY in the hypothalamic PVN of the rat Am. J. Physiol. 275 1998 R471 R477
41. P.J. Kulkosky, G.W. Glazner, H.T. Moore, C.A. Low, and S.C. Woods Neuropeptide Y: behavioral effects in the golden hamster Peptides 9 1989 1389 1393
42. J.G. Mercer Regulation of appetite and body weight in seasonal mammals Comp. Biochem. Physiol. 119C 1998 295 303
43. J.G. Mercer, C.B. Lawrence, B. Beck, A. Burlet, T. Atkinson, and P. Barrett Hypothalamic NPY and prepro-NPY mRNA in Djungarian hamsters: effects of food deprivation and photoperiod Am. J. Physiol. 269 1995 R1099 R1106
44. J.G. Mercer, K.M. Moar, A.W. Ross, N. Hoggard, and P.J. Morgan Photoperiod regulates arcuate nucleus POMC, AGRP, and leptin receptor mRNA in Siberian hamster hypothalamus Am. J. Physiol. 278 2000 R271 R281
45. J.E. McMinn, R.J. Seeley, C.W. Wilkinson, P.J. Havel, S.C. Woods, and M.W. Schwartz NPY-induced overfeeding suppresses hypothalamic NPY mRNA expression: potential roles of plasma insulin and leptin Regul. Pept. 75-76 1998 425 431
46. G.J. Morton, and M.W. Schwartz The NPY/AgRP neuron and energy homeostasis Int. J. Obes. Relat. Metab. Disord., Suppl. 5 2001 S56 S62
47. J. Rafael, P. Vsiansky, and G. Heldmaier Increased contribution of brown adipose tissue to nonshivering thermogenesis in the Djungarian hamster during cold-adaptation J. Comp. Physiol., B 155 1985 717 722
48. D.V. Rayner, and P. Trayhurn Regulation of leptin production: sympathetic nervous system interactions J. Mol. Med. 79 2001 8 20
49. A.B. Reddy, A.S. Cronin, H. Ford, and F.J.P. Ebling Seasonal regulation of food intake and body weight in the male Siberian hamster: studies of hypothalamic orexin (hypocretin), neuropeptide Y (NPY), and pro-opiomelanocortin (POMC) Eur. J. Neurosci. 11 1999 3255 3264
50. R.D. Richardson, T. Boswell, B.D. Rafferty, R.J. Seeley, J.C. Wingfield, and S.C. Woods NPY increases food intake in white-crowned sparrows: effect in short and long photoperiods Am. J. Physiol. 268 1995 R1418 R1422
51. A.K. Roscoe, and R.D. Myers Hypothermia and feeding induced simultaneously in rats by perfusion of neuropeptide Y in preoptic area Pharmacol. Biochem. Behav. 39 1991 1003 1009
52. N.F. Ruby Paraventricular nucleus ablation disrupts daily torpor in Siberian hamsters Brain Res. Bull. 37 1995 193 198
53. N.F. Ruby, and I. Zucker Daily torpor in the absence of the suprachiasmatic nucleus in Siberian hamsters Am. J. Physiol. 263 1992 R353 R362
54. T. Ruf, and G. Heldmaier The impact of daily torpor on energy requirements in the Djungarian hamster, Phodopus sungorus Physiol. Zool. 68 1992 994 1010
55. T. Ruf, A. Steiglitz, S. Steinlechner, J.L. Blank, and G. Heldmaier Cold exposure and food restriction facilitate physiological responses to short photoperiod in Djungarian hamsters (Phodopus sungorus) J. Exp. Zool. 267 1993 104 112
56. M.W. Schwartz, D.G. Figlewicz, D.G. Baskin, S.C. Woods, and D. Porte Insulin in the brain: a hormonal regulator of energy balance Endocr. Rev. 13 1992 387 414
57. V. Sergeyev, C. Broberger, O. Gorbatyuk, and T. Hökfelt Effect of 2-mercaptoacetate and 2-deoxy-d-glucose administration on the expression of NPY, AGRP, POMC, MCH, and hypocretin/orexin in the rat hypothalamus NeuroReport 11 2000 117 121
58. T. Shiraishi, and M. Mager Hypothermia following injection of 2-deoxy-d-glucose into selected hypothalamic sites Am. J. Physiol. 239 1980 R265 R269
59. J.L. Stamper, and J. Dark Metabolic fuel availability influences thermoregulation in deer mice (Peromyscus maniculatus) Physiol. Behav. 61 1997 521 524
60. B. Uzsoki, A. Fekete, E. Petervari, M. Balasko, and M. Szekely Enhanced responsiveness to central prostaglandin E or neuropeptide Y in cold-adapted rats J. Therm. Biol. 26 2001 499 504
61. G. van Dijk The role of leptin in the regulation of energy balance and adiposity J. Neuroendocrinol. 13 2001 913 921
62. H.C. Walker, and D.R. Romsos Similar effects of NPY on energy metabolism and on plasma insulin in adrenalectomized ob/ob and lean mice Am. J. Physiol. 264 1993 E226 E230
63. J. Weiner Limits to energy budget and tactics in energy investments during reproduction in Djungarian hamster (Phodopus sungorus sungorus Pallas 1770) Symp. Zool. Soc. London 57 1987 167 187
64. W. Westwood, and F. Geiser The effect of metabolic fuel availability on thermoregulation and torpor in a marsupial hibernator J. Comp. Physiol. 174 2004 49 57
65. A.N. Wick, D.R. Drury, H.I. Nakada, and J.B. Wolfe Localization of the primary metabolic block produced by 2-deoxy-glucose J. Biol. Chem. 224 1957 963 969
66. G. Williams, C. Bing, X.J. Cai, J.A. Harrold, P.J. King, and X.H. Liu The hypothalamus and the control of energy homeostasis: different circuits, different purposes Physiol. Behav. 74 2001 683 701