The effect of metabolic fuel availability on thermoregulation and torpor in a marsupial hibernator

Journal of Comparative Physiology B: Biochemical, Systemic, and Environmental Physiology

Volumn 174, Issue 1, 2004, Pages 49-57

  Westman, W ^a   Geiser, F ^a  

^a UNIVERSITY OF NEW ENGLAND   (Australia)

Author keywords

2 Deoxy D glucose; Cercartetus nanus; Mercaptoacetate; Metabolic fuel deprivation; Torpor

Indexed keywords

DEOXYGLUCOSE; FATTY ACID; GLUCOSE;

ADAPTATION; ANIMAL; ARTICLE; BODY TEMPERATURE; BROWN ADIPOSE TISSUE; COMPARATIVE STUDY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENERGY METABOLISM; HIBERNATION; MARSUPIAL; METABOLISM; PHYSIOLOGY; THERMOREGULATION; TIME;

ADAPTATION, PHYSIOLOGICAL; ADIPOSE TISSUE, BROWN; ANIMALS; BODY TEMPERATURE; BODY TEMPERATURE REGULATION; DEOXYGLUCOSE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENERGY METABOLISM; FATTY ACIDS; GLUCOSE; HIBERNATION; MARSUPIALIA; TIME FACTORS;

EID: 0442298686     PISSN: 01741578     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00360-003-0388-y     Document Type: Article

References (39)

1. Atgie C, Nibbelink M, Ambid L (1990) Sympathoadrenal activity and hypoglycemia in the hibernating garden dormouse. Physiol Behav 48:783-787
2. Bartholomew GA, Hudson JW (1962) Hibernation, estivation, temperature regulation, evaporative water loss, and heart rate of the pigmy possum, Cercaertus nanus. Physiol Zool 35:94-107
3. Bauché F, Saourault D, Giudicelli Y, Nordmann J, Nordmann R (1983) Inhibition in vitro of acyl-CoA dehydrogenases by 2-mercaptoacetate in rat liver mitochondria. Biochem J 215:457-464
4. Boyer BB, Barnes BM (1999) Molecular and metabolic aspects of mammalian hibernation. BioScience 49:713:124
5. Dark J, Ruby NF (1993) Metabolic fuel utilization during hibernation. In: Carey C, Florant GL, Wunder BA, Horwitz B (eds) Life in the cold: ecological, physiological, and molecular mechanisms. Westview, Boulder, pp 167-174
6. Dark J, Miller DR (1998) Metabolic fuel privation in hibernating and awake ground squirrels. Physiol Behav 63:59-65
7. Dark J, Miller DR, Zucker I (1994) Reduced glucose availability induces torpor in Siberian hamsters. Am J Physiol 267:R496-R501
8. Dark J, Miller DR, Licht P, Zucker I (1996) Glucoprivation counteracts effects of testosterone on daily torpor in Siberian hamsters. Am J Physiol 270:R398-R403
9. Dark J, Lewis DA, Zucker I (1999) Hypoglycemia and torpor in Siberian hamsters. Am J Physiol 276:R776-R781
10. Dawson TJ (1989) Responses to cold of monotremes and marsupials. In: Wang LCH (ed) Advances in comparative and environmental physiology 4. Springer, Berlin Heidelberg New York
11. Egawa M, Yoshimatsu H, Bray GA (1989) Effects of 2-deoxy-D-glucose on sympathetic nerve activity to interscapular brown adipose tissue. Am J Physiol 257:R1377-R1385
12. Geiser F (1988) Reduction of metabolism during hibernation and daily torpor in mammals and birds: temperature effect of physiological inhibition? J Comp Physiol B 158:25-37
13. Geiser F (1993) Hibernation in the eastern pygmy possum, Cercartetus nanus (Marsupialia: Burramyidae). Aust J Zool 41:67-75
14. Geiser F, Baudinette RV (1985) The influence of temperature and photophase on daily torpor in Sminthopsis macroura (Dasyuridae: Marsupialia). J Comp Physiol B 156:129-134
15. Geiser F, Broome LS (1991) Hibernation in the mountain pygmy possum Burramysparvus (Marsupialia). J Zool (Lond) 223:593-602
16. Geiser F, Körtner G, Schmidt I (1998) Leptin increases energy expenditure of a marsupial by inhibition of daily torpor. Am J Physiol 275:R1627-R1632
17. Heldmaier G, Klingenspor M, Werneyer M, Lampi BJ, Brooks SP, Storey KB (1999) Metabolic adjustments during daily torpor in the Djungarian hamster. Am J Physiol 276:E896-E906
18. Heller HC, Colliver GW, Beard J (1977) Thermoregulation during entrance into hibernation. Pflügers Arch 369:55-59
19. Hume I (1999) Marsupial nutrition. Cambridge University Press, Cambridge
20. Körtner G, Brigham RM, Geiser F (2001) Torpor in free-ranging tawny frogmouths (Podargus strigoides) Physiol Biochem Zool 74:789-797
21. Nedergaard J, Cannon B (1984) Preferential utilization of brown adipose tissue lipids during arousal from hibernation in hamsters. Am J Physiol 247:R506-R512
22. Nestler JR (1990) Relationships between respiratory quotient and metabolic rate during entry to and arousal from daily torpor in deer mice (Peromyscus maniculatus). Physiol Zool 63:504-515
23. Nestler JR (1991) Metabolic substrate change during daily torpor in deer mice. Can J Zool 69:322-327
24. Nicol SC, Pavlides D, Andersen NA (1997) Nonshivering thermogenesis in marsupials: absence of thermogenic response to β3-adrenergic agonists. Comp Biochem Physiol A 117:399-405
25. Nizielski SE, Billington CJ, Levine AS (1989) Brown fat GDP binding and circulating metabolites during hibernation and arousal. Am J Physiol 257:R536-R541
26. Schneider JE, Friedenson DG, Hall AJ, Wade GN (1993) Glucoprivation induces anestrus and lipoprivation may induce hibernation in Syrian hamsters. Am J Physiol 264:R573-R577
27. Shiraishi T, Mager M (1980a) Hypothermia following injection of 2-deoxy-D-glucose into selected hypothalamic sites. Am J Physiol 239:R265-R269
28. Shiraishi T, Mager M (1980b) 2-deoxy-D-glucose-induced hypothermia: thermoregulatory pathways in rat. Am J Physiol 239:R270-R276
29. Snapp BD, Heller HC (1981) Suppression of metabolism during hibernation in ground squirrels (Citellus lateralis). Physiol Zool 54:297-307
30. Song X, Körtner G, Geiser F (1997) Thermal relations of metabolic rate reduction in a hibernating marsupial. Am J Physiol 273:R2097-R2104
31. Song X, Körtner G, Geiser F (1998) Temperature selection and use of torpor by the marsupial Sminthopsis macroura. Physiol Behav 64:675-682
32. Stamper JL, Dark J (1997) Metabolic fuel availability influences thermoregulation in deer mice (Peromyscus maniculatus). Physiol Behav 61:521-524
33. Stamper JL, Dark J, Zucker I (1999) Photoperiod modulates torpor and food intake in Siberian hamsters challenged with metabolic inhibitors. Physiol Behav 66:113-118
34. Tucker VA (1962) Diurnal torpidity in the Californian pocket mouse. Science 136:380-381
35. Twente JW, Twente JA (1967) Concentrations of D-glucose in the blood of Citellus lateralis after known intervals of hibernating periods. J Mamm 48:381-386
36. Westman W, Geiser F (2003) Captive breeding, growth, and development of thermoregulation in the eastern pygmy-possum (Cercartetus nanus) In: Goldingay RL, Jackson SM (eds) The biology of Australian possums and gliders. Southern Cross University Press, Lismore (In Press)
37. Wick AN, Drury DR, Nakada HI, Wolfe JB (1957) Localization of the primary metabolic block produced by 2-Deoxyglucose. J Biol Chem 224:963-969
38. Willis JS (1982) Intermediary metabolism in hibernation. In: Lyman CP, Willis JS, Malan A, Wang LCH (eds) Hibernation and torpor in mammals and birds. Academic Press, New York, pp 124-139
39. 2, and evaporative water loss with a flow-through mask. J Appl Physiol 42:120-123