Leptin increases energy expenditure of a marsupial by inhibition of daily torpor

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 275, Issue 5 44-5, 1998, Pages

  Geiser, Fritz ^a   Körtner, Gerhard ^a   Schmidt, Ingrid ^b  

^a UNIVERSITY OF NEW ENGLAND   (Australia)

^b MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

Author keywords

Body temperature; Metabolic rate; Sminthopsis macroura; Thermoregulation

Indexed keywords

LEPTIN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BODY MASS; BODY TEMPERATURE; DOG; ENERGY EXPENDITURE; MALE; MARSUPIAL; METABOLIC RATE; NONHUMAN; PHYLOGENY; PRIORITY JOURNAL;

EID: 0031766887     PISSN: 03636119     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpregu.1998.275.5.r1627     Document Type: Article

References (32)

1. Ahima, R. S., D. Prabakaran, C. Mantzoros, D. Qu, B. Lowell, E. Maratos-Flier, and J. S. Flier. Role of leptin in the neuroendocrine response to fasting. Nature 382: 250-252, 1996.
2. Considine, R. V., and J. F. Caro. Leptin and the regulation of body weight. Int. J. Biochem. Cell Biol. 29: 1255-1272, 1997.
3. Döring, H., M. Olbort, K. Schwarzer, B. Nuesslein-Hildesheim, and I. Schmidt. Leptin effects on metabolic rate, food intake and body composition of mice (Abstract). Pflügers Arch., Suppl. 435: R230, 1998.
4. Döring, H., K. Schwarzer, B. Nuesslein-Hildesheim, and I. Schmidt. Leptin selectively increases energy expenditure of food-restricted lean mice. Int. J. Obes. 22: 83-88, 1998.
5. Fleury, C., M. Neverova, S. Collins, S. Raimbault, O. Champigny, C. Levi-Meyrueis, F. Bouillaud, M. F. Seldin, R. S. Surwit, D. Ricquier, and C. H. Warden. Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia. Nat. Genet. 15: 269-272, 1997.
6. Flier, J. S. Leptin expression and action: new experimental paradigms. Proc. Natl. Acad. Sci. USA 94: 4242-4245, 1997.
7. Flier, J. S., and J. K. Elmquist. Energetic pursuit of leptin function. Nat. Biotechnol. 15: 20-21, 1997.
8. Friedman, J. M. The alphabet of weight control. Nature 385: 119-120, 1997.
9. Geiser, F., and R. V. Baudinette. Seasonality of torpor and thermoregulation in three dasyurid marsupials. J. Comp. Physiol. [B] 157: 335-344, 1987.
10. Geiser, F., and G. J. Kenagy. Torpor duration in relation to temperature and metabolism in hibernating ground squirrels. Physiol. Zool. 61: 442-449, 1988.
11. Geiser, F., and T. Ruf. Hibernation versus daily torpor in mammals and birds: physiological variables and classification of torpor patterns. Physiol. Zool. 68: 935-966, 1995.
12. 2 exposure on metabolic rate, thermoregulation, and thermal conductance during normothermia and daily torpor. J. Comp. Physiol. [B] 166: 190-196, 1996.
13. Halaas, J. L., C. Boozer, J. Blair-West, N. Fidahusein, D. A. Denton, and J. M. Friedman. Physiological response to long-term peripheral and central leptin infusion in lean and obese mice. Proc. Natl. Acad. Sci. USA 94: 8878-8883, 1997.
14. Heller, H. C., and H. T. Hammel. CNS control of body temperature during hibernation Comp. Biochem. Physiol. A Physiol. 41: 349-359, 1972.
15. Hope, P. J., G. A. Wittert, I. Chapman, M. Horowitz, and J. Morley. The effect of diet on the response to leptin in the marsupial Sminthopsis crassicaudata (Abstract). Proc. Aust. NZ Soc. Comp. Physiol. Biochem. 14: 27, 1997.
16. Hudson, J. W. Torpidity in mammals. In: Comparative Physiology of Thermoregulation, edited by G. C. Whittow. New York: Academic, 1973, p. 97-165.
17. Hwa, J. J., A. B. Fawzi, M. P. Graziano, L. Ghibaudi, P. Williams, M. van Heek, H. Davis, M. Rudinski, E. Sybertz, and C. D. Strader. Leptin increases energy expenditure and selectively promotes fat metabolism in ob/ob mice. Am. J. Physiol. 272 (Regulatory Integrative Comp. Physiol. 41): R1204-R1209, 1997.
18. Landsberg, L., and J. B. Young. Autonomic regulation of thermogenesis. In: Mammalian Thermogenesis, edited by L. Giradier and M. J. Stock. London: Chapman and Hall, 1983, p. 99-140.
19. Nedergaard, J., and B. Cannon. The uncoupling protein thermogenin and mitochondrial thermogenesis. In: Molecular Mechanisms in Bioenergetics, edited by L. Ernster. Amsterdam, The Netherlands: Elsevier, 1992, p. 385-420.
20. Nicol, S., D. Pavlides, and N. A. Andersen. Nonshivering thermogenesis in marsupials: absence of thermogenic response to β3-adrenergic agonists. Comp. Biochem. Physiol. A Physiol. 117: 399-405, 1997.
21. Pelleymounter, M. A. Leptin and the physiology of obesity. Curr. Pharmaceut. Design 3: 85-98, 1997.
22. Pelleymounter, M. A., M. J. Cullen, M. B. Baker, R. Hecht, D. Winters, T. Boone, and F. Collins. Effects of the obese gene product on body weight regulation in ob/ob mice. Science 269: 540-543, 1995.
23. Schmidt, I., H. Döring, O. Stehling, B. Nuesslein-Hildesheim, S. Steinlechner, and K. Schwarzer. Leptin disinhibits rather than stimulates sympathetically mediated energy expenditure. In: Leptin - The Voice of the Adipose Tissue, edited by W. F. Blum, W. Kiess, and W. Rascher. Heidelberg, Germany: Barth Verlag, 1997, p. 133-139.
24. Siegrist-Kaiser, C. A., V. Pauli, C. E. Juge-Aubry, O. Boss, A. Pernin, W. W. Chin, I. Cusin, F. Rohner-Jeanrenaud, A. G. Burger, J. Zapf, and C. A. Meier. Direct effects of leptin on brown and white adipose tissue. J. Clin. Invest. 100: 2858-2864, 1997.
25. Song, X., and F. Geiser. Daily torpor and energy expenditure in Sminthopsis macroura: interactions between food and water availability and temperature. Physiol. Zool. 70: 331-337, 1997.
26. Song, X., G. Körtner, and F. Geiser. Reduction of metabolic rate and thermoregulation during daily torpor. J. Comp. Physiol. [B] 165: 291-297, 1995.
27. Stehling, O., H. Döring, J. Ertl, G. Preibisch, and I. Schmidt. Leptin reduces juvenile fat stores by altering the circadian cycle of energy expenditure. Am. J. Physiol. 271 (Regulatory Integrative Comp. Physiol. 40): R1770-R1774, 1996.
28. Stehling, O., H. Döring, B. Nuesslein-Hildesheim, M. Olbert, and I. Schmidt. Leptin does not reduce body fat content but augments cold defense abilities in thermoneutrally reared pups. Pflügers Arch. 434: 694-697, 1997.
29. Trayhurn, P., and D. V. Rayner. Hormones and the ob gene product (leptin) in the control of energy balance. Biochem. Soc. Trans. 24: 565-570, 1996.
30. Vidal-Puig, A., G. Solanes, D. Grujic, J. S. Flier, and B. B. Lowell. UCP3: an uncoupling protein homologue expressed preferentially and abundantly in skeletal muscle and brown adipose tissue. Biochem. Biophys. Res. Commun. 235: 79-82, 1997.
31. 2, and evaporative water loss with a flow-through mask. J. Appl. Physiol. 42: 120-123, 1977.
32. Zhou, Y., M. Shimabukuro, K. Koyama, Y. Lee, M. Y. Wang, F. Trieu, C. B. Newgard, and R. H. Unger. Induction by leptin of uncoupling protein-2 and enzymes of fatty acid oxidation. Proc. Natl. Acad. Sci. USA 94: 6386-6390, 1997.